{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T18:10:23Z","timestamp":1682964623465},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[1979,5,1]],"date-time":"1979-05-01T00:00:00Z","timestamp":294364800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Blut"],"published-print":{"date-parts":[[1979,5]]},"DOI":"10.1007\/bf01007902","type":"journal-article","created":{"date-parts":[[2005,1,19]],"date-time":"2005-01-19T09:28:46Z","timestamp":1106126926000},"page":"407-420","source":"Crossref","is-referenced-by-count":5,"title":["Polycythemia vera: Electron microscopy of the bone marrow in 10 non-treated patients","Polycyth\ufffdmia vera: Elektronenmikroskopische Befunde am Knochenmark von zehn unbehandelten Patienten"],"prefix":"10.1007","volume":"38","author":[{"given":"J.","family":"Thiele","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Stangel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. F.","family":"Vykoupil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Georgii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1056\/NEJM197610212951702","volume":"295","author":"J.W. Adamson","year":"1976","unstructured":"Adamson, J.W., Fialkow, P.J., Murphy, S., Prchal, J.F., Steinmann, L.: Polycythemia vera: stem-cell and probable clonal origin of the disease. N. Engl. J. Med.295, 913?916 (1976)","journal-title":"N. Engl. J. Med."},{"key":"CR2","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1038\/215196a0","volume":"215","author":"M.J. Ahearn","year":"1967","unstructured":"Ahearn, M.J., Lewis, C.W., Campbell, L.A., Luce, J.K.: Nuclear bleb formation in human bone cells during cytosine arabinoside therapy. Nature (London)215, 196?197 (1967)","journal-title":"Nature (London)"},{"key":"CR3","first-page":"2887","volume":"34","author":"M.J. Ahearn","year":"1974","unstructured":"Ahearn, M.J., Trujillo, J.M., Cork, A., Fowler, A., Hart, J.S.: The association of nuclear blebs with aneuploidy in human acute leukemia. Cancer Res.34, 2887?2896 (1974)","journal-title":"Cancer Res."},{"key":"CR4","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/BF01634375","volume":"28","author":"M. Albrecht","year":"1974","unstructured":"Albrecht, M., F\u00fclle, H.-H.: Morphologie der Megakaryozyten bei Blutkrankheiten. Blut28, 109?121 (1974)","journal-title":"Blut"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1056\/NEJM197308092890608","volume":"289","author":"R.D. Barr","year":"1973","unstructured":"Barr, R.D., Fialkow, P.J.: Clonal origin of chronic myelocytic leukemia. N. Engl. J. Med.289, 307?309 (1973)","journal-title":"N. Engl. J. Med."},{"key":"CR6","first-page":"339","volume":"12","author":"N.I. Berlin","year":"1975","unstructured":"Berlin, N.I.: Diagnosis and classification of the polycythemias. Semin. Hematol.12, 339?351 (1975)","journal-title":"Semin. Hematol."},{"key":"CR7","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/j.1365-2141.1978.tb07106.x","volume":"38","author":"B. Bj\u00f6rkst\u00e9n","year":"1978","unstructured":"Bj\u00f6rkst\u00e9n, B., Holmgren, G., Roos, G., Stenling, R.: Congenital dyserythropoietic anaemia type III: an electron microscopic study. Br. J. Haematol.38, 37?42 (1978)","journal-title":"Br. J. Haematol."},{"key":"CR8","first-page":"23","volume":"13","author":"J. Breton-Gorius","year":"1973","unstructured":"Breton-Gorius, J., Daniel, M.T., Clauvel, J.P., Dreyfus, B.: Anomalies ultrastructurales des \u00e9rythroblastes et des \u00e9rythrocytes dans six cas de dys\u00e9rythropo\u00cf\u00e8se cong\u00e9n\u00cctale. Nouv. Rev. Fr. Hematol.13, 23?50 (1973)","journal-title":"Nouv. Rev. Fr. Hematol."},{"key":"CR9","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1007\/BF01633163","volume":"14","author":"R. Burkhardt","year":"1966","unstructured":"Burkhardt, R.: Pr\u00e4parative Voraussetzungen zur klinischen Histologie des menschlichen Knochenmarkes. Blut14, 30?46 (1966)","journal-title":"Blut"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/BF02889212","volume":"22","author":"A. Conforti","year":"1976","unstructured":"Conforti, A., Medolago-Albani, L., Alessio, L.: Ultrastructural changes in human leukemic cell nuclei. Virchows Archiv [Cell Pathol.]22, 143?149 (1976)","journal-title":"Virchows Archiv [Cell Pathol.]"},{"key":"CR11","first-page":"209","volume":"10","author":"G. Duhamel","year":"1970","unstructured":"Duhamel, G., Najman, A., Andr\u00e9, R.: L'histologie de la moelle osseuse dans la maladie de Vaquez et le probl\u00e8me de la my\u00e9loscl\u00e9rose. A propos de 70 biopsies. Nouv. Rev. Fr. Hematol.10, 209?222 (1970)","journal-title":"Nouv. Rev. Fr. Hematol."},{"key":"CR12","first-page":"205","volume":"9","author":"J.F. Duplan","year":"1969","unstructured":"Duplan, J.F., Bessis, M., Breton-Gorius, J.: Les appendices nucl\u00e9aires (caryoschizes) des granulocytes apr\u00e8s irradiation g\u00e9nerale. Etude au microscope \u00e9lectronique. Nouv. Rev. Fr. Hematol.9, 205?214 (1969)","journal-title":"Nouv. Rev. Fr. Hematol."},{"key":"CR13","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1159\/000208235","volume":"52","author":"A. Dvilansky","year":"1974","unstructured":"Dvilansky, A., Sukenik, S., Stern, J., Djaldetti, M.: Congenital dyserythropoietic anemia with ultrastructure findings compatible with both types I and II. Acta Haematol. (Basel)52, 161?168 (1974)","journal-title":"Acta Haematol. (Basel)"},{"key":"CR14","first-page":"433","volume":"12","author":"J.T. Ellis","year":"1975","unstructured":"Ellis, J.T., Silver, R.T., Coleman, M., Geller, S.A.: The bone marrow in polycythemia vera. Semin. Hematol.12, 433?444 (1975)","journal-title":"Semin. Hematol."},{"key":"CR15","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1073\/pnas.58.4.1468","volume":"58","author":"P.J. Fialkow","year":"1967","unstructured":"Fialkow, P.J., Gartler, S.M., Yoshida, A.: Clonal origin of chronic myelocytic leukemia in man. Proc. Natl. Acad. Sci. USA58, 1468?1471 (1967)","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"CR16","first-page":"283","volume":"458","author":"P.J. Fialkow","year":"1976","unstructured":"Fialkow, P.J.: Clonal origin of human tumors. Biochim. Biophys. Acta Cancer Reviews458, 283?321 (1976)","journal-title":"Acta Cancer Reviews"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0002-9343(77)90124-3","volume":"63","author":"P.J. Fialkow","year":"1977","unstructured":"Fialkow, P.J., Jacobson, R.J., Papayannopoulou, T.: Chronic myelocytic leukemia: clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte\/macrophage. Am. J. Med.63, 125?130 (1977)","journal-title":"Am. J. Med."},{"key":"CR18","unstructured":"Fialkow, P.J., Denman, A.M., Singer, J., Jacobson, R.J., Lowenthal, M.N.: Human myeloproliferative disorders: clonal origin in pluripotent stem cells. Proc. 5th Cold Spring Harbor Conf. on Cell Prolif., 1978 (in press) (1979)"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/j.1365-2141.1975.tb02741.x","volume":"29","author":"B. Frisch","year":"1975","unstructured":"Frisch, B., Lewis, S.M., Sherman, D.: The ultrastructure of dyserythropoiesis in aplastic anaemia. Br. J. Haematol.29, 545?552 (1975)","journal-title":"Br. J. Haematol."},{"key":"CR20","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1182\/blood.V37.3.299.299","volume":"37","author":"H. Heimpel","year":"1971","unstructured":"Heimpel, H., Forteza-Vila, J., Queisser, W., Spiertz, E.: Electron and light microscopic study of the erythroblasts of patients with congenital dyserythropoietic anemia. Blood37, 299?310 (1971)","journal-title":"Blood"},{"key":"CR21","first-page":"11","volume":"26","author":"G. Hug","year":"1972","unstructured":"Hug, G., Wong, K.Y., Lampkin, B.C.: Congenital dyserythropoietic anemia type II. Lab. Invest.26, 11?21 (1972)","journal-title":"Lab. Invest."},{"key":"CR22","first-page":"453","volume":"4","author":"E. Ikkala","year":"1967","unstructured":"Ikkala, E., Rapola, J., Kotilainen, M.: Polycythaemia vera and myelofibrosis. Scand. J. Haematol.4, 453?464 (1967)","journal-title":"J. Haematol."},{"key":"CR23","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1111\/j.1365-2141.1966.tb00134.x","volume":"12","author":"H.E.M. Kay","year":"1966","unstructured":"Kay, H.E.M., Lawler, S.D., Millard, R.E.: The chromosomes in polycythaemia vera. Br. J. Haematol.12, 507?527 (1966)","journal-title":"Br. J. Haematol."},{"key":"CR24","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/BF03160505","volume":"26","author":"G. Krasznai","year":"1969","unstructured":"Krasznai, G., Nagy, G., R\u00e1cz, M.: Bone marrow biopsy in polycythaemia vera. Acta Med. Acad. Sci. Hung.26, 309?316 (1969)","journal-title":"Acta Med. Acad. Sci. Hung."},{"key":"CR25","unstructured":"Krmpotic, E., Stangel, W., Vykoupil, K.F., Georgii, A.: Chromosomal anomalies in polycythemia vera and related conditions. Blut, (submitted) (1979)"},{"key":"CR26","first-page":"489","volume":"94","author":"J.E. Kurnick","year":"1972","unstructured":"Kurnick, J.E., Ward, H.P., Block, M.H.: Bone marrow sections in the differential diagnosis of polycythemia. Arch. Pathol.94, 489?499 (1972)","journal-title":"Arch. Pathol."},{"key":"CR27","first-page":"240","volume":"16","author":"B. Lagerl\u00f6f","year":"1972","unstructured":"Lagerl\u00f6f, B.: Cytophotometric study of megakaryocyte ploidy in polycythemia vera and chronic granulocytic leukemia. Acta Cytol. (Baltimore)16, 240?244 (1972)","journal-title":"Acta Cytol. (Baltimore)"},{"key":"CR28","first-page":"71","volume":"80","author":"B. Lagerl\u00f6f","year":"1972","unstructured":"Lagerl\u00f6f, B., Franz\u00e9n, S.: The ultrastructure of megakaryocytes in polycythaemia vera and chronic granulocytic leukaemia. Acta Pathol. Microbiol. Scand.80, 71?83 (1972)","journal-title":"Acta Pathol. Microbiol. Scand."},{"key":"CR29","first-page":"409","volume":"12","author":"J. Laszlo","year":"1975","unstructured":"Laszlo, J.: Myeloproliferative disorders (MPD): myelofibrosis, myelosclerosis, extramedullary hematopoiesis, undifferentiated MPD, and hemorrhagic thrombocythemia. Semin. Hematol.12, 409?432 (1975)","journal-title":"Semin. Hematol."},{"key":"CR30","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0014-2964(70)90025-3","volume":"6","author":"S.D. Lawler","year":"1970","unstructured":"Lawler, S.D., Millard, R.E., Kay, H.E.M.: Further cytogenetical investigations in polycythaemia vera. Eur. J. Cancer6, 223?233 (1970)","journal-title":"Eur. J. Cancer"},{"key":"CR31","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/j.1365-2141.1972.tb03465.x","volume":"23","author":"S.M. Lewis","year":"1972","unstructured":"Lewis, S.M., Nelson, D.A., Pitcher, C.S.: Clinical and ultrastructural aspects of congenital dyserythropoietic anaemia type I. Br. J. Haematol.23, 113?119 (1972)","journal-title":"Br. J. Haematol."},{"key":"CR32","first-page":"99","volume":"8","author":"S.M. Lewis","year":"1973","unstructured":"Lewis, S.M., Verwilghen, R.L.: Dyserythropoiesis and dyserythropoietic anemias. Prog. Hematol.8, 99?129 (1973)","journal-title":"Prog. Hematol."},{"key":"CR33","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1600-0609.1972.tb00940.x","volume":"9","author":"P.M. Lundin","year":"1972","unstructured":"Lundin, P.M., Ridell, B., Weinfeld, A.: The significance of bone marrow morphology for the diagnosis of polycythaemia vera. Scand. J. Haematol.9, 271?282 (1972)","journal-title":"Scand. J. Haematol."},{"key":"CR34","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1182\/blood.V44.4.495.495","volume":"44","author":"J.E. Maldonado","year":"1974","unstructured":"Maldonado, J.E., Taswell, H.F.: Type I dyserythropoietic anemia in an elderly patient. Blood44, 495?500 (1974)","journal-title":"Blood"},{"key":"CR35","first-page":"167","volume":"2","author":"J.E. Maldonado","year":"1976","unstructured":"Maldonado, J.E., Maigne, J., Lecoq, D.: Comparative electron-microscopic study of the erythrocytic line in refractory anemia (preleukemia) and myelomonocytic leukemia. Blood Cells2, 167?185 (1976)","journal-title":"Blood Cells"},{"key":"CR36","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S0308-2261(21)00084-9","volume":"4","author":"B. Modan","year":"1975","unstructured":"Modan, B.: Inter-relationship between polycythaemia vera, leukaemia and myeloid metaplasia. Clin. Haematol.4, 427?439 (1975)","journal-title":"Clin. Haematol."},{"key":"CR37","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1172\/JCI109003","volume":"61","author":"J.F. Prchal","year":"1978","unstructured":"Prchal, J.F., Adamson, J.W., Murphy, S., Steinmann, L., Fialkow, P.J.: Polycythemia vera: the in vitro response of normal and abnormal stem cell lines to erythropoietin. J. Clin. Invest.61, 1044?1047 (1978)","journal-title":"J. Clin. Invest."},{"key":"CR38","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1159\/000208608","volume":"45","author":"W. Queisser","year":"1971","unstructured":"Queisser, W., Spiertz, E., Jost, E., Heimpel, H.: Proliferation disturbances of erythroblasts in congenital dyserythropoietic anemia type I and II. Acta Haematol. (Basel)45, 65?76 (1971)","journal-title":"Acta Haematol. (Basel)"},{"key":"CR39","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/BF01000172","volume":"32","author":"W. Queisser","year":"1976","unstructured":"Queisser, W., Weidenauer, G., Queisser, U., Kempgens, U., M\u00fcller, U.: Megakaryocyte polyploidization in myeloproliferative disorders. Blut32, 13?20 (1976)","journal-title":"Blut"},{"key":"CR40","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1365-2141.1969.tb00380.x","volume":"16","author":"B.E. Roberts","year":"1969","unstructured":"Roberts, B.E., Miles, D.W., Woods, C.G.: Polycythaemia vera and myelosclerosis: a bone marrow study. Br. J. Haematol.16, 75?85 (1969)","journal-title":"Br. J. Haematol."},{"key":"CR41","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1001\/archinte.1974.00320190115016","volume":"134","author":"M.N. Silverstein","year":"1974","unstructured":"Silverstein, M.N.: Postpolycythemia myeloid metaplasia. Arch. Intern. Med.134, 113?115 (1974)","journal-title":"Arch. Intern. Med."},{"key":"CR42","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1002\/1097-0142(196509)18:9<1071::AID-CNCR2820180904>3.0.CO;2-F","volume":"18","author":"R.C. Stalzer","year":"1965","unstructured":"Stalzer, R.C., Kiely, J.M., Pease, G.L., Brown, A.L., Jr.: Effect of 5-Fluorouracil on human hematopoiesis. Cancer18, 1071?1078 (1965)","journal-title":"Cancer"},{"key":"CR43","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/BF00432237","volume":"373","author":"J. Thiele","year":"1977","unstructured":"Thiele, J., Ballard, A.-Ch., Georgii, A., Vykoupil, K.F.: Chronic megakaryocytic-granulocytic myelosis ? an electron microscopic study. I. Megakaryocytes and Thrombocytes. Virchows Arch. [Pathol. Anat]373, 191?211 (1977)","journal-title":"Virchows Arch. [Pathol. Anat]"},{"key":"CR44","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/BF00428101","volume":"375","author":"J. Thiele","year":"1977","unstructured":"Thiele, J., Ballard, A.-Ch., Georgii, A., Vykoupil, K.F.: Chronic megakaryocytic-granulocytic myelosis ? an electron microscopic study including freeze-fracture. II. Granulocytes, Erythrocytes, Plasma Cells and Myeloid Stroma. Virchows Arch. [Pathol. Anat.]375, 129?146 (1977)","journal-title":"Virchows Arch. [Pathol. Anat.]"},{"key":"CR45","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1007\/BF01632297","volume":"20","author":"E. Undritz","year":"1970","unstructured":"Undritz, E., Nusselt-Bohaumilitzky, K.: \u00fcber das Auftreten von diploiden Megakaryoblasten, Promegakaryozyten und Megakaryozyten bei schweren H\u00e4mopathien, ein R\u00fcckgriff in die Phylogenese. Blut20, 242?249 (1970)","journal-title":"Blut"},{"key":"CR46","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/BF00995915","volume":"32","author":"K.F. Vykoupil","year":"1976","unstructured":"Vykoupil, K.F., Thiele, J., Georgii, A.: Histochemical and immunohistochemical techniques on acrylate embedded bone biopsies. Blut32, 215?218 (1976)","journal-title":"Blut"},{"key":"CR47","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1097\/00005792-197109000-00001","volume":"50","author":"H.P. Ward","year":"1971","unstructured":"Ward, H.P., Block, M.H.: The natural history of agnogenic myeloid metaplasia (AMM) and a critical evaluation of its relationship with the myeloproliferative syndrome. Medicine50, 357?420 (1971)","journal-title":"Medicine"},{"key":"CR48","first-page":"13","volume":"13","author":"D. Wurster-Hill","year":"1976","unstructured":"Wurster-Hill, D., Whang-Peng, J., McIntyre, O.R., Hsu, L.Y.F., Hirschhorn, K., Modan, B., Pisciotta, A.V., Pierre, R., Balcerzak, S.P., Weinfeld, A., Murphy, S.: Cytogenetic studies in polycythemia vera. Semin. Hematol.13, 13?32 (1976)","journal-title":"Semin. Hematol."}],"container-title":["Blut"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01007902.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01007902\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01007902","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T17:40:10Z","timestamp":1682962810000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01007902"}},"subtitle":["A thin section and freeze-fracture study","Eine Untersuchung mit Hilfe der D\ufffdnnschnitt- und Gefrierbrechungsmethode"],"short-title":[],"issued":{"date-parts":[[1979,5]]},"references-count":48,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1979,5]]}},"alternative-id":["BF01007902"],"URL":"https:\/\/doi.org\/10.1007\/bf01007902","relation":{},"ISSN":["0006-5242","1432-0584"],"issn-type":[{"value":"0006-5242","type":"print"},{"value":"1432-0584","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,5]]}}}