{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T13:29:50Z","timestamp":1770989390605,"version":"3.50.1"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[1994,9,1]],"date-time":"1994-09-01T00:00:00Z","timestamp":778377600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cancer Res Clin Oncol"],"published-print":{"date-parts":[[1994,9]]},"DOI":"10.1007\/bf01221027","type":"journal-article","created":{"date-parts":[[2005,2,25]],"date-time":"2005-02-25T20:46:41Z","timestamp":1109364401000},"page":"513-518","source":"Crossref","is-referenced-by-count":67,"title":["Induction of differentiation in the cultured F9 teratocarcinoma stem cells by triterpene acids"],"prefix":"10.1007","volume":"120","author":[{"given":"Ho-Young","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hae-Young","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ki-Heun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jung-Joon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyu-Won","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"MM Bradford","year":"1976","unstructured":"Bradford MM (1976) A rapid and sensitive method for quantification of microgram quantities of protein utilizing the principles of proteindye binding. Anal Biochem 72:248?254","journal-title":"Anal Biochem"},{"key":"CR2","first-page":"6268","volume":"50","author":"TR Breitman","year":"1990","unstructured":"Breitman TR, He R (1990) Combinations of retinoic acid with either sodium butyrate, dimethyl sulfoxide, or hexamethylene bisacetamide synergistically induce differentiation of the human myeloid leukemia cell line HL60. Cancer Res 50:6268?6273","journal-title":"Cancer Res"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/0092-8674(83)90430-0","volume":"33","author":"VL Chandler","year":"1983","unstructured":"Chandler VL, Maler BA, Yamamoto KR (1983) DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo. Cell 33:489?499","journal-title":"Cell"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0003-2697(87)90021-2","volume":"162","author":"P Chomczynski","year":"1987","unstructured":"Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid-guanidinium thiocyanate-phenol-choloform extraction. Anal Biochem 162:156?159","journal-title":"Anal Biochem"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1093\/nar\/11.5.1475","volume":"11","author":"JD Dignam","year":"1983","unstructured":"Dignam JD, Lebowitz RM, Roeder RG (1983) Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11:1475?1489","journal-title":"Nucleic Acids Res"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1126\/science.3283939","volume":"240","author":"RM Evans","year":"1988","unstructured":"Evans RM (1988) The steroid and thyroid hormone receptor superfamily. Science 240:889?895","journal-title":"Science"},{"key":"CR7","first-page":"255","volume":"137","author":"AP Feinberg","year":"1984","unstructured":"Feinberg AP, Vogelstein B (1984) Technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 137:255?267","journal-title":"Anal Biochem"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/0012-1606(86)90213-7","volume":"114","author":"A Grover","year":"1986","unstructured":"Grover A, Adamson ED (1986) Evidence for the expression of an early common biochemical pathway in the differentiation of F9 cells into visceral and parietal endoderm: modulation by cyclic AMP. Dev Biol 114:492?503","journal-title":"Dev Biol"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1089\/cdd.1986.3.101","volume":"3","author":"CI Hong","year":"1986","unstructured":"Hong CI, Kirisits AJ, Buchheit DJ, Nechaev A, West CR (1986) 1-?-d-Arabinofuranosylcytosine conjugates of thioether phospholipids as a new class of potential antitumor drugs. Cancer Drug Deliv 3:101?113","journal-title":"Cancer Drug Deliv"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1056\/NEJM199009203231205","volume":"323","author":"WK Hong","year":"1990","unstructured":"Hong WK, Lippman SM, Itri LM, Karp DD, Lee JS, Byers RM, Schantz SP, Kramer AM, Lotan R, Peter LJ, Dimery IW, Brown BW, Goepfert H (1990) Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck. N Engl J Med 323:795?801","journal-title":"N Engl J Med"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1200\/JCO.1993.11.5.959","volume":"11","author":"JS Lee","year":"1993","unstructured":"Lee JS, Newman RA, Lippman SM, Huber MH, Minor T, Raber MN, Krakoff IH, Hong WK (1993) Phase I evaluation of all-trans-retinoic acid in adults with solid tumors. J Clin Oncol 11:959?966","journal-title":"J Clin Oncol"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"3588","DOI":"10.1073\/pnas.90.8.3588","volume":"90","author":"AP Madan","year":"1983","unstructured":"Madan AP, Defranco DB (1983) Bidirectional transport of glucocorticoid receptors across the nuclear envelope. Proc Natl Acad Sci USA 90:3588?3592","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/0012-1606(85)90005-3","volume":"108","author":"KR Marotti","year":"1985","unstructured":"Marotti KR, Brown GD, Strickland S (1985) Two-stage hormonal control of type IV collagen mRNA levels during differentiation of F9 teratocarcinoma cells. Dev Biol 108:26?31","journal-title":"Dev Biol"},{"key":"CR14","first-page":"5210","volume":"48","author":"H Nishino","year":"1988","unstructured":"Nishino H, Nishino A, Takayasu J, Hasegawa T, Iwashima A, Hirabayashi K, Iwata S, Shibaa S (1988) Inhibition of the tumor-promoting action of 12-O-tetradecanoylphorbol-13-acetate by some oleananetype triterpenoid compounds. Cancer Res 48:5210?5215","journal-title":"Cancer Res"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0304-3835(86)90082-0","volume":"30","author":"H Ohigashi","year":"1986","unstructured":"Ohigashi H, Takamura H, Koshimizu H, Tokuda H, Ito Y (1986) Search for possible antitumor promoters by inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus activation; ursolic acid and oleanolic acid from an anti-inflammatory Chinese medicinal plant,Glechoma hederaceae L. Cancer Lett 30:143?151","journal-title":"Cancer Lett"},{"key":"CR16","unstructured":"Sambrook J, Fritsch EF, Maniatis T (1989) Condition for hybridization of oligonucleotide probes, in: Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor, NY, pp 11.45?11.57"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1038\/304749a0","volume":"304","author":"C Scheidereit","year":"1983","unstructured":"Scheidereit C, Geisse S, Westphal HM, Beato M (1983) The glucocorticoid receptor binds to defined nucleotide sequences near the promoter of mouse mammary tumor. Nature 304:749?752","journal-title":"Nature"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1073\/pnas.84.7.1744","volume":"84","author":"CM Silva","year":"1987","unstructured":"Silva CM, Tully DB, Petch LA, Jewell CM, Cidlowski JA (1987) Amplication of a protein-blotting procedure to the study of human glucocorticoid receptor interactions with DNA. Proc Natl Acad Sci USA 84:1744?1748","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR19","first-page":"3034","volume":"43","author":"MB Sporn","year":"1983","unstructured":"Sporn MB, Roberts AB (1983) Role of retinoids in differentiation and carcinogenesis. Cancer Res 43:3034?3040","journal-title":"Cancer Res"},{"key":"CR20","first-page":"222","volume":"50","author":"VL Stevens","year":"1990","unstructured":"Stevens VL, Owens NF, Winton EF, Kinkade JM, Merill AH (1990) Modulation of retinoic acid-induced differentiation of human leukemia (HL-60) cells by serum factors and sphinganine. Cancer Res 50:222?226","journal-title":"Cancer Res"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/0092-8674(78)90008-9","volume":"15","author":"S Strickland","year":"1978","unstructured":"Strickland S, Madhavi V (1978) The induction of differentiation in teratocarcinoma cells by retinoic acid. Cell 15:393?403","journal-title":"Cell"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/0012-1606(80)90319-X","volume":"78","author":"S Strickland","year":"1980","unstructured":"Strickland S, Sawey MJ (1980) Studies on the effect of retinoids on the differentiation of teratocarcinoma cells in vitro and in vivo. Dev Biol 78:76?85","journal-title":"Dev Biol"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/0092-8674(80)90471-7","volume":"21","author":"S Strickland","year":"1980","unstructured":"Strickland S, Smith KK, Marotti KR (1980) Hormonal induction of differentiation in teratocarcinoma stem cells: generation of parietal endoderm by retinoic acid and dibutyryl cyclic AMP. Cell 21:347?355","journal-title":"Cell"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1248\/cpb.37.340","volume":"37","author":"T Tanaka","year":"1989","unstructured":"Tanaka T, Moriomoto S, Nonaka G, Nishioka I, Yokozawa T, Chung HY, Oura H (1989) Magnesium and ammonium-potassium lithospermates B, the active principles having a uremia-preventive effect fromSalvia miltiorrhiza. Chem Pharm Bull (Tokyo) 37:340?344","journal-title":"Chem Pharm Bull (Tokyo)"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0304-3835(86)90067-4","volume":"33","author":"H Tokuda","year":"1986","unstructured":"Tokuda H, Ohigashi H, Koshimizu K, Ito Y (1986) Inhibitory effects of ursolic acid and oleanolic acid on skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. Cancer Lett 33:279?285","journal-title":"Cancer Lett"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1248\/cpb.40.401","volume":"40","author":"K Umehara","year":"1992","unstructured":"Umehara K, Takagi R, Kuroyanagi M, Ueno A, Taki T, Chen YJ (1992) Studies on differentiation-inducing activities of triterpenes. Chem Pharm Bull (Tokyo) 40:401?405","journal-title":"Chem Pharm Bull (Tokyo)"},{"key":"CR27","first-page":"2367","volume":"40","author":"AK Verma","year":"1980","unstructured":"Verma AK, Slaga TJ, Wertz PW, Mueller GC, Boutwell RK (1980) Inhibition of skin tumor promotion by retinoic acid and its metabolite 5,6-epoxy-retinoic acid. Cancer Res 40:2367?2371","journal-title":"Cancer Res"}],"container-title":["Journal of Cancer Research and Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01221027.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01221027\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01221027","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,30]],"date-time":"2019-04-30T09:38:11Z","timestamp":1556617091000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01221027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,9]]},"references-count":27,"journal-issue":{"issue":"9","published-print":{"date-parts":[[1994,9]]}},"alternative-id":["BF01221027"],"URL":"https:\/\/doi.org\/10.1007\/bf01221027","relation":{},"ISSN":["0171-5216","1432-1335"],"issn-type":[{"value":"0171-5216","type":"print"},{"value":"1432-1335","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,9]]}}}