{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T01:38:13Z","timestamp":1759541893480},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[1982,5,1]],"date-time":"1982-05-01T00:00:00Z","timestamp":389059200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digest Dis Sci"],"published-print":{"date-parts":[[1982,5]]},"DOI":"10.1007\/bf01295645","type":"journal-article","created":{"date-parts":[[2005,3,24]],"date-time":"2005-03-24T22:26:44Z","timestamp":1111703204000},"page":"388-393","source":"Crossref","is-referenced-by-count":11,"title":["Cimetidine or propantheline combined with antacid therapy for short-term treatment of duodenal ulcer"],"prefix":"10.1007","volume":"27","author":[{"given":"Hans-olov","family":"Adami","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olle","family":"Bj\ufffdrklund","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars-Krister","family":"Enander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sven","family":"Gustavsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"L\ufffd\ufffdf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arne","family":"Nordahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anders","family":"Ros\ufffdn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/S0140-6736(76)92347-3","volume":"2","author":"WS Blackwood","year":"1976","unstructured":"Blackwood WS, Maudgal DP, Pickard RG, Lawrence D: Cimetidine in duodenal ulcer. Controlled trial, Lancet 2:174?176, 1976","journal-title":"Lancet"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0140-6736(76)92342-4","volume":"2","author":"G Bodemar","year":"1976","unstructured":"Bodemar G, Walan A.: Cimetidine in the treatment of active duodenal and prepyloric ulcers., Lancet 2:161?164, 1976","journal-title":"Lancet"},{"key":"CR3","doi-asserted-by":"crossref","unstructured":"Multicenter trial: Comparison of two doses of cimetidine and placebo in the treatment of duodenal ulcer: A multicentre trial. Gut 20:68?74, 1979","DOI":"10.1136\/gut.20.1.68"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0140-6736(78)91200-X","volume":"1","author":"G Bodemar","year":"1978","unstructured":"Bodemar G, Walan A: Maintenance treatment of recurrent peptic, ulcer by cimetidine. Lancet 1:403?407, 1978","journal-title":"Lancet"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/0016-5085(78)90770-9","volume":"74","author":"GR Gray","year":"1978","unstructured":"Gray GR, Smith IS, Mackenzie I, Gillespie G: Long-term cimetidine in the management of severe duodenal dyspepsia. Gastroenterology 74:397?401, 1978","journal-title":"Gastroenterology"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/0016-5085(78)90768-0","volume":"74","author":"AF Ippoliti","year":"1978","unstructured":"Ippoliti AF, Sturdevant RAL, Isenberg JI, Binder M, Camacho R, Cano R, Cooney C, Kline MM, Koretz RL, Meyer JH, Samloff IM, Schwabe AD, Strom EA, Valenquela JE, Wintroub RH: Cimetidine versus intensive antacid therapy for duodenal ulcer. Gastroenterology 74:393?395, 1978","journal-title":"Gastroenterology"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1136\/gut.21.4.329","volume":"21","author":"G Vantrappen","year":"1980","unstructured":"Vantrappen G, Rutgeerts P, Broeckaert L, Janssens J: Randomised open controlled trial of colloidal bismuth subcitrate tablets and cimetidine in the treatment of duodenal ulcer. Gut 21:329?33, 1980","journal-title":"Gut"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1056\/NEJM198002213020802","volume":"302","author":"HJ Priebe","year":"1980","unstructured":"Priebe HJ, Skillman JJ, Bushnell LS, Long PG, Silen W: Antacid versus cimetidine in preventing acute gastrointestinal bleeding. A randomized trial in 75 critically ill patients. N Engl J Med 302:426?430, 1980","journal-title":"N Engl J Med"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1007\/BF01308303","volume":"25","author":"J Teres","year":"1980","unstructured":"Teres J, Bordas JM, Rimola A, Bru C, Rodes J: Cimetidine in acute gastric mucosal bleeding. Results of a double-blind randomized trial Dig Dis Sci 25:92?96 (1980)","journal-title":"Dig Dis Sci"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"103","DOI":"10.3109\/00365528009181439","volume":"15","author":"HE Carstensen","year":"1980","unstructured":"Carstensen HE, B\u00fclow S, Hansen OH, Jakobsen BH, Krarup T, Pedersen T, Raahave D, Svendsen LB, Backer O: Cimetidine for severe gastroduodenal haemorrhage: A randomized controlled trial. Scand J Gastroenterol 15:103?105, 1980","journal-title":"Scand J Gastroenterol"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1002\/cpt1977226825","volume":"6","author":"\u00d6 Nordle","year":"1977","unstructured":"Nordle \u00d6, Brantmark G: A self-adjusting randomization plan for allocation of patients into two treatment groups. Clin Pharm Ther 6:825?830, 1977","journal-title":"Clin Pharm Ther"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/j.0954-6820.1968.tb02444.x","volume":"184","author":"J M\u00f6ller","year":"1968","unstructured":"M\u00f6ller J, Ros\u00e9n A: Comparative studies on intramuscular and oral effective doses of some anticholinergic drugs. Acta Med Scand 184:201?209, 1968","journal-title":"Acta Med Scand"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1002\/jps.2600660825","volume":"66","author":"WC Randolph","year":"1977","unstructured":"Randolph WC, Osborne VL, Walkenstein SS, Intoccia AP: High-pressure liquid chromatographic analysis of cimetidine, a, histamin H2-receptor antagonist in blood and urine. J Pharm Sci 66:1148?1150, 1977","journal-title":"J Pharm Sci"},{"key":"CR14","volume-title":"Statistics in Medicine","author":"T Colton","year":"1974","unstructured":"Colton T: Statistics in Medicine. Boston, Little, Brown and Company, 1974"},{"key":"CR15","first-page":"442","volume":"87","author":"DCH Sun","year":"1956","unstructured":"Sun DCH, Shay H: Optimal effective dose of anticholinergic drug in peptic ulcer therary Arch Intern Med 87:442?452, 1956","journal-title":"Arch Intern Med"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/S0016-5085(75)80048-5","volume":"68","author":"FA Bieberdorf","year":"1975","unstructured":"Bieberdorf FA, Walsh JH, Fordtran JS: Effect of optimum therapeutic dose of poldine on acid secretion, gastric acidity, gastric emptying, and serum gastrin concentration after a protein meal. Gastroenterology 68:50?57, 1975","journal-title":"Gastroenterology"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/S0016-5085(75)80062-X","volume":"68","author":"KJ Ivey","year":"1975","unstructured":"Ivey KJ: Anticholinergics: Do they work in peptic ulcer? Gastroenterology 68:154?166, 1975","journal-title":"Gastroenterology"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1056\/NEJM197712292972603","volume":"26","author":"M Feldman","year":"1977","unstructured":"Feldman M, Richardson CT, Peterson WL, Walsh JH, Fordtran JS: Effect of low-dose propantheline on foodstimulated gastric acid secretion N Engl J Med 26:1427?1430, 1977","journal-title":"N Engl J Med"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/S0140-6736(79)90924-3","volume":"1","author":"G Bodemar","year":"1979","unstructured":"Bodemar G, Norlander B, Walan A: Diminished absorption of cimetidine caused by antacids. Lancet 1:444?445, 1979 (letter)","journal-title":"Lancet"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1002\/cpt1972132212","volume":"13","author":"B Beermann","year":"1972","unstructured":"Beermann B, Hellstr\u00f6m K, Ros\u00e9n A: On the metabolism of propantheline in man. Clin Pharm Ther 13:212?220, 1972","journal-title":"Clin Pharm Ther"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"963","DOI":"10.3109\/00365527709181357","volume":"12","author":"G Ekenved","year":"1977","unstructured":"Ekenved G, Magnusson A, Bodemar G, Walan A: Influence of food on the effect of propantheline and 1-hyoscyamine on salivation Scand J Gastroenterol 12:963?966, 1977","journal-title":"Scand J Gastroenterol"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/0016-5085(78)90766-7","volume":"74","author":"HJ Binder","year":"1978","unstructured":"Binder HJ, Cocco A, Crossley RJ, Finkelstein W, Font R, Friedman G, Groarke J, Hughes W, Johnson AF, McGuigan JE, Summers R, Vlahcevic R, Wilson EC, Winship, DH: Cimetidine in the treatment of duodenal ulcer. Gastroenterology 74:380?388, 1978","journal-title":"Gastroenterology"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/0016-5085(79)90339-1","volume":"76","author":"SK Lam","year":"1979","unstructured":"Lam SK, Lam KC, Lai CL, Yeung CK, Yam LYC, Wong WS: Treatment of duodenal ulcer with antacid and sulpiride. Gastroenterology 76:315?322, 1979","journal-title":"Gastroenterology"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1056\/NEJM197708182970701","volume":"297","author":"WL Peterson","year":"1977","unstructured":"Peterson WL, Sturdevant RAL, Frankl HD, Richardson CT, Isenberg JI, Elashoff JD, Sones JQ, Gross RA, McCulhun RW, Fordtran JS: Healing of duodenal ulcer with an antacid regimen. N Engl J Med 297:341?345, 1977","journal-title":"N Engl J Med"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1136\/gut.20.2.158","volume":"20","author":"KD Bardhan","year":"1979","unstructured":"Bardhan KD, Saul DM, Edwards JL, Smith PM, Haggie SJ, Wyllie JH, Duthie HL, Fussey IV: Double-blind comparison of cimetidine and placebo in the maintenance of healing of chronic duodenal ulceration. Gut 20:158?162, 1979","journal-title":"Gut"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01295645.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01295645\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01295645","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,6]],"date-time":"2020-04-06T13:36:43Z","timestamp":1586180203000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01295645"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,5]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1982,5]]}},"alternative-id":["BF01295645"],"URL":"https:\/\/doi.org\/10.1007\/bf01295645","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,5]]}}}