{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T00:30:00Z","timestamp":1771633800424,"version":"3.50.1"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[1985,5,1]],"date-time":"1985-05-01T00:00:00Z","timestamp":483753600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digest Dis Sci"],"published-print":{"date-parts":[[1985,5]]},"DOI":"10.1007\/bf01318177","type":"journal-article","created":{"date-parts":[[2005,3,26]],"date-time":"2005-03-26T03:32:50Z","timestamp":1111807970000},"page":"445-455","source":"Crossref","is-referenced-by-count":38,"title":["Effects of intravenous infusion of amino acids, fat, or glucose on unstimulated pancreatic secretion in healthy humans"],"prefix":"10.1007","volume":"30","author":[{"given":"Claus","family":"Niederau","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amnon","family":"Sonnenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joachim","family":"Erckenbrecht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","first-page":"241","volume":"82","author":"EP DiMagno","year":"1973","unstructured":"DiMagno EP, Go VLW, Summerskill WHJ: Intraluminal and postabsorptive effects of amino acids on pancreatic enzyme secretion. J Lab Clin Med 82:241?248, 1973","journal-title":"J Lab Clin Med"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/S0016-5085(19)33430-4","volume":"61","author":"A Ertan","year":"1971","unstructured":"Ertan A, Brooks FP, Ostrow JD, Arbau DA, Williams CN, Cerda JC: Effects of jejunal amino acid perfusion and exogenous cholecystokinin on exocrine pancreatic and biliary secretion in man. Gastroenterology 61:686?692, 1971","journal-title":"Gastroenterology"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1172\/JCI106373","volume":"49","author":"VLW Go","year":"1970","unstructured":"Go VLW, Hofman AF, Summerskill WZ: Pancreozymin bioassay in man based on pancreatic enzyme secretion. Potency of specific amino acids and other digestive products. J Clin Invest 49:1558?1564, 1970","journal-title":"J Clin Invest"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1007\/BF01468558","volume":"51","author":"C Froehlich","year":"1973","unstructured":"Froehlich C, Locher M, Oldershausen HF: Die Beeinflussung des exokrinen Pankreas durch die intravenoese Infusion einer Naehrloesung. Klin Wochenschr 51:1207?1209, 1973","journal-title":"Klin Wochenschr"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1159\/000176280","volume":"23","author":"R Stastna","year":"1979","unstructured":"Stastna R, Skala I, Hruba F, Shlygin GK, Sysoev Y: The effect of someN-solutions for parenteral nutrition on gastric and pancreatic secretion. Nutr Metab 23:349?356, 1979","journal-title":"Nutr Metab"},{"key":"CR6","first-page":"E678","volume":"236","author":"SJ Konturek","year":"1979","unstructured":"Konturek SJ, Tasler JT, Cieszkowski M, Jaworek J, Konturek J: Intravenous amino acids and fat stimulate pancreatic secretion. Am J Physiol 236:E678-E684, 1979","journal-title":"Am J Physiol"},{"key":"CR7","first-page":"31","volume":"78","author":"E Klein","year":"1983","unstructured":"Klein E, Shnebaum S, Ben-Ari H, Dreiling DA: Effects of total parenteral nutrition on exocrine pancreatic secretion. Am J Gastroenterol 78:31?33, 1983","journal-title":"Am J Gastroenterol"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/BF02468955","volume":"11","author":"S Matsuno","year":"1981","unstructured":"Matsuno S, Miyashita E, Sasaki K, Sato T: Effects of intravenous fat emulsion administration on exocrine and endocrine pancreatic function. Jpn J Surg 11:323?329, 1981","journal-title":"Jpn J Surg"},{"key":"CR9","first-page":"G274","volume":"246","author":"BE Stabile","year":"1984","unstructured":"Stabile BE, Borzatta M, Stubbs RS, Debas HT: Intravenous mixed amino acids and fats do not stimulate exocrine pancreatic secretion. Am J Physiol 246 (Gastrointest Liver Physiol 9):G274-G280, 1984","journal-title":"Am J Physiol"},{"key":"CR10","first-page":"902","volume":"92","author":"GM Fried","year":"1982","unstructured":"Fried GM, Ogden WD, Rhea A, Greeley G, Thompson JC: Pancreatic protein secretion and gastrointestinal hormone release in response to parenteral amino acids and lipid in dogs. Surgery 92:902?905, 1982","journal-title":"Surgery"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/S0016-5085(83)80072-9","volume":"85","author":"K Edelmann","year":"1983","unstructured":"Edelmann K, Valenzuela JE: Effect of intravenous lipid on human pancreatic secretion. Gastroenterology 85:1063?1066, 1983","journal-title":"Gastroenterology"},{"key":"CR12","first-page":"G445","volume":"246","author":"JH Grendell","year":"1984","unstructured":"Grendell JH, Tseng HC, Rothman SS: Regulation of digestion. I. Effects of glucose and lysine on pancreatic secretion. Am J Physiol 246 (Gastrointest Liver Physiol 9):G445-G450, 1984","journal-title":"Am J Physiol"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/S0016-5085(19)34232-5","volume":"53","author":"SJ Malawer","year":"1967","unstructured":"Malawer SJ, Powell DW: An improved turbidimetric analysis of polyethylen glycol utilizing an emulsifier. Gastroenterology 53:250?256, 1967","journal-title":"Gastroenterology"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0003-9861(61)90145-X","volume":"95","author":"BF Erlanger","year":"1961","unstructured":"Erlanger BF, Kokowsky N, Cohen W: The preparation and the proper ties of two new chromogenic substrates of trypsin. Arch Biochem 95:217?278, 1961","journal-title":"Arch Biochem"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1515\/bchm2.1965.340.1-2.1","volume":"340","author":"W Nagel","year":"1965","unstructured":"Nagel W, Willig F, Peschke W, Schmidt FH: Ueber die Bestimmung von Trypsin und Chymotrypsin mit Amino-p-nitroaniliden. Z Physiol Chem 340:1?10, 1965","journal-title":"Z Physiol Chem"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0378-4347(00)80069-9","volume":"223","author":"EO Haegele","year":"1981","unstructured":"Haegele EO, Schaich E, Rauscher E, Lehmann P, Grassl M: Action pattern of human pancreatic alpha-amylase on maltoheptaose. J Chromatogr 223:69?84, 1981","journal-title":"J Chromatogr"},{"key":"CR17","first-page":"356","volume-title":"Handbuch der inneren Medizin, Dritter Band, Teil 6, Pankreas","author":"W Rick","year":"1976","unstructured":"Rick W: Diagnostische Verfahren, Klinisch-chemische Methoden.In Handbuch der inneren Medizin, Dritter Band, Teil 6, Pankreas. MM Forell (ed). Berlin, Springer 1976, pp 356?361"},{"issue":"Suppl","key":"CR18","first-page":"1","volume":"128","author":"HO Lagerloef","year":"1942","unstructured":"Lagerloef HO: Pancreatic function and disease. Acta Med Scand Suppl 128:1?13, 1942","journal-title":"Acta Med Scand"},{"key":"CR19","volume-title":"Statistical Methods, Chapter 10; Correlation","author":"GW Snedecor","year":"1980","unstructured":"Snedecor GW, Cochran WG: Statistical Methods, Chapter 10; Correlation. Ames, Iowa, The Iowa State University Press, 1980"},{"key":"CR20","first-page":"42","volume":"22","author":"C Niederau","year":"1984","unstructured":"Niederau C, Erckenbrecht J, Hellmann A, Sonnenberg A: Intravenoese Infusionen von Fettemulsionen mit mittel- und langkettigen Triglyzeriden (MCT\/LCT) haben keine Auswirkungen auf die basale und die sekretinstimulierte Pankreassekretion beim Menschen. Z Gastroenterol 22:42?46, 1984","journal-title":"Z Gastroenterol"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1097\/00005373-196907000-00008","volume":"9","author":"R Zajtchuk","year":"1969","unstructured":"Zajtchuk R, Amato JC, Shoemaker WC, Baker RJ: The relationship between blood glucose levels and external pancreatic secretion in man. J Trauma 9:629?635, 1969","journal-title":"J Trauma"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0016-5085(76)80009-1","volume":"70","author":"IL MacGregor","year":"1976","unstructured":"MacGregor IL, Deveney C, Way LW, Meyer JH: The effect of acute hyperglycemia on meal-stimulated gastric, biliary, and pancreatic secretion, and serum gastrin. Gastroenterology 70:197?202, 1976","journal-title":"Gastroenterology"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1620\/tjem.124.99","volume":"124","author":"Y Saito","year":"1978","unstructured":"Saito Y, Tokutake K, Matsuno S, Noto N, Honda T, Sato T: Effects of hypertonic glucose and amino acid infusions on pancreatic exocrine function. Tohoku J Exp Med 124:99?115, 1978","journal-title":"Tohoku J Exp Med"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1111\/j.1748-1716.1982.tb07088.x","volume":"115","author":"M Raeder","year":"1982","unstructured":"Raeder M, Mathisen \u00d8: Effect of intravenous infusion of hypertonic glucose solutions on pancreatic HCO3 ? secretion. Acta Physiol Scand 115:349?354, 1982","journal-title":"Acta Physiol Scand"},{"key":"CR25","first-page":"311","volume":"28","author":"H Sommer","year":"1981","unstructured":"Sommer H, Kasper H: The action of synthetic secretin, cholecystokinin-octapeptide and combinations of these hormones on the secretion of the isolated perfused rat pancreas. Hepato-gastroenterol 28:311?315, 1981","journal-title":"Hepato-gastroenterol"},{"key":"CR26","unstructured":"Niederau C, Grendell JH, Rothman SS: The effects of proglumide on pancreatic secretion of digestive enzymes. Am J Physiol (submitted)"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1152\/ajplegacy.1974.226.1.77","volume":"226","author":"SS Rothman","year":"1974","unstructured":"Rothman SS: Molecular regulation by the pancreas: Shortterm and bond-specific. Am J Physiol 226:77?83, 1974","journal-title":"Am J Physiol"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1152\/ajplegacy.1976.231.6.1847","volume":"231","author":"SS Rothman","year":"1976","unstructured":"Rothman SS: Independent secretion of different digestive enzymes by the pancreas. Am J Physiol 231:1847?1851, 1976","journal-title":"Am J Physiol"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1152\/ajplegacy.1943.138.4.676","volume":"138","author":"MI Grossman","year":"1981","unstructured":"Grossman MI, Greengard H, Ivy AC: The effect of dietary composition on pancreatic enzymes. Am J Physiol 138:676?682, 1981","journal-title":"Am J Physiol"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/0006-291X(63)90482-0","volume":"13","author":"G Marchis-Mouren","year":"1963","unstructured":"Marchis-Mouren G, Pasero L, Desnuelle P: Further studies of amylase biosynthesis by pancreas of rats fed on a starchrich or a casein-rich diet. Biochem Biophys Res Commun 13:262?266, 1963","journal-title":"Biochem Biophys Res Commun"},{"key":"CR31","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/0006-291X(66)90608-5","volume":"22","author":"JP Reboud","year":"1966","unstructured":"Reboud JP, Marchis-Mouren G, Cozzone A, Desnuelle P: Variation in the biosynthesis rate of pancreatic amylase and chymotrypsinogen in response to a starch-rich or a proteinrich diet. Biochem Biophys Res Commun 22:94?99, 1966","journal-title":"Biochem Biophys Res Commun"},{"key":"CR32","first-page":"276","volume":"10","author":"A Bucko","year":"1968","unstructured":"Bucko A, Kopec Z: Adaptation of enzymes activity of the rat pancreas on altered food intake. Nutr Dieta Basel 10:276?287, 1968","journal-title":"Nutr Dieta Basel"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0022-2275(20)36904-2","volume":"14","author":"LL Gidez","year":"1973","unstructured":"Gidez LL: Effect of dietary fat on pancreatic lipase level in the rat. J Lipid Res 14:169?171, 1973","journal-title":"J Lipid Res"},{"key":"CR34","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1152\/ajplegacy.1971.221.5.1383","volume":"221","author":"JT Snook","year":"1971","unstructured":"Snook JT: Dietary regulation of pancreatic enzymes in the rat with emphasis on carbohydrate. Am J Physiol 221:1383?1387, 1971","journal-title":"Am J Physiol"},{"key":"CR35","unstructured":"Walther AA: The secretory work of the pancreatic gland. PhD thesis. St. Petersberg, Russia, 1897"},{"key":"CR36","volume-title":"The Work of the Digestive Glands","author":"IP Pavlov","year":"1910","unstructured":"Pavlov IP: The Work of the Digestive Glands. London, Griffith, 1910."},{"key":"CR37","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1093\/ajcn\/24.3.329","volume":"24","author":"RD Feigin","year":"1971","unstructured":"Feigin RD, Beisel WR, Wannemacher RW: Rhythmicity of plasma amino acids and relation to dietary intake. Am J Nutr 24:329?336, 1971","journal-title":"Am J Nutr"},{"key":"CR38","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1093\/ajcn\/9.3.356","volume":"9","author":"JB Longenecker","year":"1961","unstructured":"Longenecker JB, Hause NL: Relationship between plasma amino acids and composition of the ingested food. Am J Nutr 9:356?362, 1961","journal-title":"Am J Nutr"},{"key":"CR39","first-page":"175","volume-title":"Modern Nutrition in Health and Disease","author":"RB Alfin-Slater","year":"1968","unstructured":"Alfin-Slater RB, Aftergood L: Absorption, digestion, and metabolism of lipids.In Modern Nutrition in Health and Disease, 4th ed. MG Wohl, RS Goodhart (eds). Philadelphia, Lea and Febiger, 1968, pp 175?212","edition":"4th ed."},{"key":"CR40","first-page":"156","volume-title":"Modern Nutrition in Health and Disease","author":"R Levine","year":"1968","unstructured":"Levine R: Role of carbohydrates in the diet.In Modern Nutrition in Health and Disease, 4th ed. MG Wohl, RS Goodhart (eds). Philadelphia, Lea and Febiger, 1968, pp 156?174","edition":"4th ed."},{"key":"CR41","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1056\/NEJM197801052980106","volume":"298","author":"JI Isenberg","year":"1978","unstructured":"Isenberg JI, Maxwell V: Intravenous infusion of amino acids stimulates gastric acid secretion in man. N Engl J Med 298:27?29, 1978","journal-title":"N Engl J Med"},{"key":"CR42","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1136\/gut.19.10.859","volume":"19","author":"SJ Konturek","year":"1978","unstructured":"Konturek SJ, Kwiecien N, Obtulowicz W, Mikos E, Sito E, Olesky J: Comparison of intraduodenal and intravenous administration of amino acids on gastric secretion in healthy subjects and patients with duodenal ulcer. Gut 19:859?864, 1978","journal-title":"Gut"},{"key":"CR43","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1111\/j.1748-1716.1961.tb02221.x","volume":"52","author":"G Dotevall","year":"1961","unstructured":"Dotevall G, Muren A: Effect of intravenous infusion of glucose on secretory responses to feeding in Pavlov- and Heidenhainpouch dogs. Acta Physiol Scand 52:234?241, 1961","journal-title":"Acta Physiol Scand"},{"key":"CR44","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/S0016-5085(73)80064-2","volume":"64","author":"JG Moore","year":"1973","unstructured":"Moore JG: Gastric acid suppression by intravenous glucose solutions. Gastroenterology 64:1106?1110, 1973","journal-title":"Gastroenterology"},{"key":"CR45","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1152\/ajplegacy.1969.216.5.1176","volume":"216","author":"LR Johnson","year":"1969","unstructured":"Johnson LR, Grossman MT: Effects of fat, secretin, and cholecystokinin on histamin-stimulated gastric secretion. Am J Physiol 216:1176?1179, 1969","journal-title":"Am J Physiol"},{"key":"CR46","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/0016-5085(80)90444-8","volume":"79","author":"AA Varner","year":"1980","unstructured":"Varner AA, Isenberg JI, Elashoff JD, Lamers CBHW, Maxwell V, Shulkes AA: Effect of intravenous lipid on gastric acid secretion stimulated by intravenous amino acids. Gastroenterology 79:873?876, 1980","journal-title":"Gastroenterology"},{"key":"CR47","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF02237664","volume":"11","author":"PE Baume","year":"1966","unstructured":"Baume PE, Meng HG, Law DH: Intravenous fat emulsion and gastric acid secretion in the rat. Am J Dig Dis 11:1?9, 1966","journal-title":"Am J Dig Dis"},{"key":"CR48","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1056\/NEJM197902013000508","volume":"300","author":"DP Kotler","year":"1979","unstructured":"Kotler DP, Levine GM: Reversible gastric and pancreatic hyposecretion after long-term total parenteral nutrition. N Engl J Med 300:241?242, 1979","journal-title":"N Engl J Med"},{"key":"CR49","first-page":"E524","volume":"233","author":"LR Johnson","year":"1977","unstructured":"Johnson LR, Schanbacher LM, Dudrick SJ, Copeland EM: Effect of long-term parenteral feeding on pancreatic secretion and serum secretin. Am J Physiol 233 (Endocrinology):E524-E529, 1977","journal-title":"Am J Physiol"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01318177.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01318177\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01318177","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T12:12:45Z","timestamp":1625659965000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01318177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,5]]},"references-count":49,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1985,5]]}},"alternative-id":["BF01318177"],"URL":"https:\/\/doi.org\/10.1007\/bf01318177","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[1985,5]]}}}