{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T11:57:51Z","timestamp":1778068671613,"version":"3.51.4"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[1994,2,1]],"date-time":"1994-02-01T00:00:00Z","timestamp":760060800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cancer Res Clin Oncol"],"published-print":{"date-parts":[[1994,2]]},"DOI":"10.1007\/bf01372559","type":"journal-article","created":{"date-parts":[[2005,4,2]],"date-time":"2005-04-02T06:01:17Z","timestamp":1112421677000},"page":"213-220","source":"Crossref","is-referenced-by-count":24,"title":["Amylase mRNA transcripts in normal tissues and neoplasms: the implication of different expressions of amylase isogenes"],"prefix":"10.1007","volume":"120","author":[{"given":"Kuniaki","family":"Seyama","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiro","family":"Nukiwa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhisa","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiro","family":"Kira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1038\/333858a0","volume":"333","author":"J Chelly","year":"1988","unstructured":"Chelly J, Kaplan J-C, Maire P, Gautron S, Kahn A (1988) Transcription of the dystrophin gene in human muscle and non-muscle tissues. Nature 333:858?860","journal-title":"Nature"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"5294","DOI":"10.1021\/bi00591a005","volume":"18","author":"JM Chirgwin","year":"1979","unstructured":"Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ (1979) Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294?5299","journal-title":"Biochemistry"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1136\/jcp.34.7.803","volume":"34","author":"PD Clarke","year":"1981","unstructured":"Clarke PD, Bain BC, Davies A, Levin GE, Lambert HP (1981) Aspiration in seriously ill patients: a study of amylase in bronchial secretions. J Clin Pathol 34:803?805","journal-title":"J Clin Pathol"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/0016-5085(78)90152-X","volume":"74","author":"MB Corlette","year":"1978","unstructured":"Corlette MB, Dratch M, Sorger K (1978) Amylase elevation attributable to an ovarian neoplasm. Gastroenterology 74:907?909","journal-title":"Gastroenterology"},{"key":"CR5","first-page":"3544","volume":"51","author":"S Doi","year":"1991","unstructured":"Doi S, Tomita N, Higasiyama M, Yokouchi H, Horii A, Yasuda T, Kobayashi T, Takai S, Ogawa M, Mori T, Matsubara K (1991) Expression of ?-amylase isozymes in human thyroid tissues. Cancer Res 51:3544?3549","journal-title":"Cancer Res"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0378-1119(88)90561-6","volume":"62","author":"M Emi","year":"1988","unstructured":"Emi M, Horrii A, Tomita N, Nishide T, Ogawa M, Mori T, Matsubara K (1988) Overlapping two genes in human DNA: a salivary amylase gene overlaps with a gamma-actin pseudogene that carries an integrated human endogenous retroviral DNA. Gene 62:229?235","journal-title":"Gene"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"5275","DOI":"10.1093\/nar\/14.13.5275","volume":"14","author":"HP Erba","year":"1986","unstructured":"Erba HP, Gunning P, Kedes L (1986) Nucleotide sequence of the human ? cytoskeletal actin mRNA: anomalous evolution of vertebrate nonmuscle actin genes. Nucleic Acids Res 14:5275?5294","journal-title":"Nucleic Acids Res"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1128\/MCB.8.4.1775","volume":"8","author":"HP Erba","year":"1988","unstructured":"Erba HP, Eddy R, Shows T, Kedes L, Gunning P (1988) Structure, chromosome location, and expression of the human ?-actin gene: differential evolution, location, and expression of the cytoskeletal ?- and ?-actin genes. Mol Cell Biol 8:1775?1789","journal-title":"Mol Cell Biol"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/S0002-9378(16)37361-6","volume":"73","author":"CL Green","year":"1957","unstructured":"Green CL (1957) Identification of alpha-amylase as a secretion of the human fallopian tube and ?tubelike? epithelium of M\u00fcllerian and mesonephric duct origin. Am J Obstet Gynecol 73:402?408","journal-title":"Am J Obstet Gynecol"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0888-7543(89)90083-9","volume":"5","author":"PC Groot","year":"1989","unstructured":"Groot PC, Bleeker MJ, Pronk JC, Arwert F, Mager WH, Planta RJ, Eriksson AW, Frants RR (1989a) The human ?-amylase multigene family consists of haplotypes with variable numbers of genes. Genomics 5:29?42","journal-title":"Genomics"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/0378-1119(89)90454-X","volume":"85","author":"PC Groot","year":"1989","unstructured":"Groot PC, Mager WH, Frants RR, Meisler MH, Samuelson LC (1989b) The human amylase-encoding genesamy2 andamy3 are identical toAMY2A andAMY2B. Gene 85:567?568","journal-title":"Gene"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1128\/MCB.8.3.1197","volume":"8","author":"DL Gumucio","year":"1988","unstructured":"Gumucio DL, Wiebauer K, Caldwell RM, Samuelson LC, Meisler MH (1988) Concerted evolution of human amylase genes. Mol Cell Biol 8:1197?1205","journal-title":"Mol Cell Biol"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1002\/1097-0142(19881015)62:8<1511::AID-CNCR2820620811>3.0.CO;2-L","volume":"62","author":"H Hata","year":"1988","unstructured":"Hata H, Matsuzaki H, Tanaka K, Nomura H, Kagimoto T, Takeya M, Yamane N, Takatsuki K (1988) Ectopic production of salivary-type amylase by a IgA-?-type multiple myeloma. Cancer 62:1511?1515","journal-title":"Cancer"},{"key":"CR14","first-page":"246","volume":"20","author":"H Hata","year":"1990","unstructured":"Hata H, Matsuzaki H, Sanada I, Takatsuki K (1990) Genetic analysis of amylase0producing cell lines: ectopic activation of the amylase gene by translocation. Jpn J Clin Oncol 20:246?251","journal-title":"Jpn J Clin Oncol"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1002\/1097-0142(19841015)54:8<1662::AID-CNCR2820540829>3.0.CO;2-U","volume":"54","author":"T Hayakawa","year":"1984","unstructured":"Hayakawa T, Kameya A, Mizuno R, Noda A, Kondo T, Hirabayashi N (1984) Hyperamylasemia with papillary serous cystadenocarcinoma of the ovary. Cancer 54:1662?1665","journal-title":"Cancer"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1007\/BF00508431","volume":"85","author":"Y Hayashi","year":"1986","unstructured":"Hayashi Y, Fukayama M, Koike M, Nakayama T (1986) Amylase in human lungs and the female genital tract. Histochemical and immuno-histochemical localization. Histochemistry 85:491?496","journal-title":"Histochemistry"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1159\/000226039","volume":"42","author":"ME Hodes","year":"1985","unstructured":"Hodes ME, Sisk CJ, Karn RC, Ehrlich CE, Lehrner LM, Roth LM, Morley DJ, Merritt AD (1985) An amylase-producing serous cystadeno-carcinoma of the ovary. Oncology 42:242?247","journal-title":"Oncology"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0378-1119(87)90213-7","volume":"60","author":"A Horii","year":"1987","unstructured":"Horii A, Emi M, Tomita N, Nishide T, Ogawa M, Mori T, Matsubara K (1987) Primary structure of human pancreatic ?-amylase gene: its comparison with human salivary ?-amylase gene. Gene 60:57?64","journal-title":"Gene"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1002\/1097-0142(19811201)48:11<2499::AID-CNCR2820481125>3.0.CO;2-8","volume":"48","author":"S Katayama","year":"1981","unstructured":"Katayama S, Ikeuchi M, Kanazawa Y, Akanuma Y, Kosaka K, Takeuchi T, Nakayama T (1981) Amlyase-producing lung cancer: case report and review of the literature. Cancer 48:2499?2502","journal-title":"Cancer"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0277-5379(82)90054-2","volume":"18","author":"M Maeda","year":"1982","unstructured":"Maeda M, Otsuki M, Yuu H, Saeki S, Yamasaki T, Baba S (1982) Salivary-type hyperamylasemia in primary lung cancer: observation of a possible precursor of the salivary-type isoamylase. Eur J Cancer Clin Oncol 18:123?128","journal-title":"Eur J Cancer Clin Oncol"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1182\/blood.V72.3.978.bloodjournal723978","volume":"72","author":"H Matsuzaki","year":"1988","unstructured":"Matsuzaki H, Hata H, Takatsuki K (1988) Establishment and characterization of an amylase-producing human myeloma cell line. Blood 72:978?982","journal-title":"Blood"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0378-1119(90)90235-J","volume":"93","author":"H Mocharla","year":"1990","unstructured":"Mocharla H, Mocharla R, Hodes ME (1990) Coupled reverse transcription-polymerase chain reaction (RT-PCR) as a sensitive and rapid method for isozyme genotyping. Gene 93:271?275","journal-title":"Gene"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0378-1119(84)90265-8","volume":"28","author":"Y Nakamura","year":"1984","unstructured":"Nakamura Y, Ogawa M, Nishide T, Emi M, Kosaki G, Himeno S, Matsubara K (1984) Sequences of cDNAs for human salivary and pancreatic ?-amylases. Gene 28:263?270","journal-title":"Gene"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0378-1119(86)90110-1","volume":"41","author":"T Nishide","year":"1986","unstructured":"Nishide T, Nakamura Y, Emi M, Yamamoto T, Ogawa M, Mori T, Matsubara K (1986a) Primary structure of human salivary ?-amylase gene. Gene 41:299?304","journal-title":"Gene"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0378-1119(86)90341-0","volume":"50","author":"T Nishide","year":"1986","unstructured":"Nishide T, Emi M, Nakamura Y, Matsubara K (1986b) Corrected sequences of cDNAs for human salivary and pancreatic ?-amylases. Gene 50:371?372","journal-title":"Gene"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1111\/j.1365-2141.1989.tb00252.x","volume":"73","author":"T Ohtsuki","year":"1989","unstructured":"Ohtsuki T, Yawata Y, Wada H, Sugihara T, Mori M, Namba M (1989) Two human myeloma cell lines, amylase-producing KMS-12-PE and amylase-non-producing KMS-12-BM, were established from a patient, having the same chromosome marker, t(11; 14)(q13;q32). Br J Haematol 73:199?204","journal-title":"Br J Haematol"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1093\/oxfordjournals.jbchem.a123895","volume":"112","author":"K Omichi","year":"1992","unstructured":"Omichi K, Hase S (1992) Detection of human urinary ?-amylase encoded by theAMY2B gene using fluorogenic substrate, FG5P. J Biochem (Tokyo) 112:303?305","journal-title":"J Biochem (Tokyo)"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1002\/1097-0142(197704)39:4<1656::AID-CNCR2820390440>3.0.CO;2-8","volume":"39","author":"M Otsuki","year":"1977","unstructured":"Otsuki M, Yuu H, Maeda M, Saeki S, Yamasaki T, Baba S (1977) Amylase in the lung. Cancer 39:1656?1663","journal-title":"Cancer"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0010-7824(72)90038-8","volume":"6","author":"F Robles","year":"1972","unstructured":"Robles F, L\u00f3pez de la Osa E, Lerner U, Johannisson E, Brenner P, Hagenfeldt K, Diczfalusy E (1972) ?-Amylase, glycogen synthetase and phosphorylase in the human endometrium: influence of the cycle and of the Cu?T device. Contraception 6:373?384","journal-title":"Contraception"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"8261","DOI":"10.1093\/nar\/16.17.8261","volume":"16","author":"LC Samuelson","year":"1988","unstructured":"Samuelson LC, Wiebauer K, Gumucio DL, Meisler MH (1988) Expression of the human amylase genes: recent origin of a salivary amylase promoter from an actin pseudogene. Nucleic Acids Res 16:8261?8276","journal-title":"Nucleic Acids Res"},{"key":"CR31","doi-asserted-by":"crossref","first-page":"2513","DOI":"10.1128\/MCB.10.6.2513","volume":"10","author":"LC Samuelson","year":"1990","unstructured":"Samuelson LC, Wiebauer K, Snow CM, Meisler MH (1990) Retroviral and pseudogene insertion sites reveal the lineage of human salivary and pancreatic amylase genes from a single gene during primate evolution. Mol Cell Biol 10:2513?2520","journal-title":"Mol Cell Biol"},{"key":"CR32","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/0002-9378(76)90513-5","volume":"126","author":"G Skude","year":"1976","unstructured":"Skude G, M\u00e5rdh PA, Westr\u00f6m L (1976) Amylases of the genital tract. I. Isoamylases of genital tract tissue homogenates and peritoneal fluid. Am J Obstet Gynecol 126:652?656","journal-title":"Am J Obstet Gynecol"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1101\/gad.6.8.1457","volume":"6","author":"C-N Ting","year":"1992","unstructured":"Ting C-N, Rosenberg MP, Snow CM, Samuelson LC, Meisler MH (1992) Endogenous retroviral sequences are required for tissue-specific expression of a human saliry amylase gene. Genes Dev 6:1457?1465","journal-title":"Genes Dev"},{"key":"CR34","first-page":"3292","volume":"48","author":"N Tomita","year":"1988","unstructured":"Tomita N, Matsuura N, Horii A, Emi M, Nishide T, Ogawa M, Mori T, Doi O, Matsubara K (1988) Expression of ?-amylase in human lung cancers. Cancer Res 48:3292?3296","journal-title":"Cancer Res"},{"key":"CR35","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0378-1119(89)90003-6","volume":"76","author":"N Tomita","year":"1989","unstructured":"Tomita N, Horii A, Doi S, Yokouchi H, Shiosaki K, Higashiyama M, Matsuura N, Ogawa M, Mori T, Matsubara K (1989) A novel type of human ?-amylase produced in lung carcinoid tumor. Gene 76:11?18","journal-title":"Gene"},{"key":"CR36","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1093\/ajcp\/21.11.1057","volume":"21","author":"MJ Weiss","year":"1951","unstructured":"Weiss MJ, Edmondson HA, Wertman M (1951) Elevated serum amylase associated with bronchogenic carcinoma. Am J Clin Pathol 21:1057?1061","journal-title":"Am J Clin Pathol"},{"key":"CR37","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0378-1119(90)90191-S","volume":"90","author":"H Yokouchi","year":"1990","unstructured":"Yokouchi H, Horii A, Emi M, Tomita N, Doi S, Ogawa M, Mori T, Matsubara K (1990) Cloning and characterization of a third type of human ?-amylase gene,AMY2B. Gene 90:281?286","journal-title":"Gene"},{"key":"CR38","doi-asserted-by":"crossref","first-page":"6932","DOI":"10.1073\/pnas.80.22.6932","volume":"80","author":"BU Zabel","year":"1983","unstructured":"Zabel BU, Naylor SL, Sakaguchi AY, Bell GI, Shows TB (1983) High-resolution chromosomal localization of human genes for amylase, proopiomelanocortin, somatostatin, and a DNA fragment (D3S1) by in situ hybridization. Proc Natl Acad Sci USA 80:6932?6936","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["Journal of Cancer Research and Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01372559.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01372559\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01372559","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,6]],"date-time":"2020-04-06T16:29:43Z","timestamp":1586190583000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01372559"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,2]]},"references-count":38,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1994,2]]}},"alternative-id":["BF01372559"],"URL":"https:\/\/doi.org\/10.1007\/bf01372559","relation":{},"ISSN":["0171-5216","1432-1335"],"issn-type":[{"value":"0171-5216","type":"print"},{"value":"1432-1335","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,2]]}}}