{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T02:47:52Z","timestamp":1769309272160,"version":"3.49.0"},"reference-count":67,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[1996,4,1]],"date-time":"1996-04-01T00:00:00Z","timestamp":828316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[1996,4,1]],"date-time":"1996-04-01T00:00:00Z","timestamp":828316800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta neurochir"],"published-print":{"date-parts":[[1996,4]]},"DOI":"10.1007\/bf01420306","type":"journal-article","created":{"date-parts":[[2005,4,11]],"date-time":"2005-04-11T19:12:58Z","timestamp":1113246778000},"page":"435-444","source":"Crossref","is-referenced-by-count":35,"title":["Arterio-jugular differences of oxygen (AVDO2) for bedside assessment of CO2-reactivity and autoregulation in the acute phase of severe head injury"],"prefix":"10.1007","volume":"138","author":[{"given":"J.","family":"Sahuquillo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. A.","family":"Poca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ausina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"B\u00e1guena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. M.","family":"Gracia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Rubio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF01420306_CR1","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1161\/01.STR.4.5.725","volume":"4","author":"RH Ackerman","year":"1973","unstructured":"Ackerman RH (1973) The relationship of cerebrovascular CO2-reactivity to blood pressure and regional resting flow. Stroke 4: 725\u2013731","journal-title":"Stroke"},{"key":"BF01420306_CR2","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1152\/jappl.1964.19.4.561","volume":"19","author":"SC Alexander","year":"1964","unstructured":"Alexander SC, Wollman H, Cohen PJ, Chase PE, Behar M (1964) Cerebral vascular response to PaCO2 during halothane anesthesia in man. J Appl Physiol 19: 561\u2013565","journal-title":"J Appl Physiol"},{"key":"BF01420306_CR3","first-page":"230","volume":"12","author":"SJ Allen","year":"1984","unstructured":"Allen SJ, Tonnesen AS, Cruz J, Mackey-Hagardine JR, Miener ME (1984) Cerebral oxygen extraction in patients with head injuries. Abstract. Crit Care Med 12: 230","journal-title":"Abstract. Crit Care Med"},{"key":"BF01420306_CR4","first-page":"396","volume-title":"Practical statistics for medical research","author":"DG Altman","year":"1991","unstructured":"Altman DG (1991) Some common problems in medical research. In: Altman DG (ed) Practical statistics for medical research. Chapman and Hall, London, pp 396\u2013439"},{"key":"BF01420306_CR5","first-page":"437","volume":"164","author":"J Bankier","year":"1995","unstructured":"Bankier J, Fleischmann D, Windisch A, Germann P, Petritschek W, Wiesmayr MN, H\u00fcbsch P (1995) Position of jugular oxygen saturation catheter in patients with head trauma: assessment by use of plain films. Am J Radiol 164: 437\u2013441","journal-title":"Am J Radiol"},{"key":"BF01420306_CR6","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/978-3-642-65814-3_16","volume-title":"Cerebral circulation and metabolism","author":"BM Bloor","year":"1975","unstructured":"Bloor BM (1975) Cerebral hemodynamics: the effect of hypoxia on autoregulation and CO2reactivity. In: Langfitt TWet al (eds) Cerebral circulation and metabolism. Springer, Berlin Heidelberg New York, pp 55\u201358"},{"key":"BF01420306_CR7","doi-asserted-by":"crossref","first-page":"368","DOI":"10.3171\/jns.1990.73.3.0368","volume":"73","author":"GJ Bouma","year":"1990","unstructured":"Bouma GJ, Muizelaar JP (1990) Relationship between cardiac output and cerebral blood flow in patients with intact and with impaired autoregulation. J Neurosurg 73: 368\u2013374","journal-title":"J Neurosurg"},{"key":"BF01420306_CR8","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/BF01407342","volume":"98","author":"GE Cold","year":"1989","unstructured":"Cold GE (1989) Measurements of CO2-reactivity and barbiturate reactivity in patients with severe head injury. Acta Neurochir (Wien) 98: 153\u2013163","journal-title":"Acta Neurochir (Wien)"},{"key":"BF01420306_CR9","first-page":"35","volume":"42","author":"J Cruz","year":"1988","unstructured":"Cruz J (1988) Continuous versus serial global cerebral hemometabolic monitoring applications in acute brain trauma. Acta Neurochir (Wien) [Suppl] 42: 35\u201339","journal-title":"Acta Neurochir (Wien) [Suppl]"},{"key":"BF01420306_CR10","first-page":"162","volume":"77","author":"J Cruz","year":"1992","unstructured":"Cruz J (1992) Jugular venous oxygen saturation monitoring (letter). J Neurosurg 77: 162\u2013163","journal-title":"J Neurosurg"},{"key":"BF01420306_CR11","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1097\/00003246-199308000-00025","volume":"21","author":"J Cruz","year":"1993","unstructured":"Cruz J (1993) Combined continuous monitoring of systemic and cerebral oxygenation in acute brain injury \u2014 preliminary observations. Crit Care Med 21: 1225\u20131232","journal-title":"Crit Care Med"},{"key":"BF01420306_CR12","first-page":"397A","volume":"76","author":"J Cruz","year":"1992","unstructured":"Cruz J, Gennarelli TA (1992) Cerebral extraction of oxygen and related variables in anemic brain-injured patients. J Neurosurg 76: 397A (Abstract)","journal-title":"J Neurosurg"},{"key":"BF01420306_CR13","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1097\/00005373-199203000-00020","volume":"32","author":"J Cruz","year":"1992","unstructured":"Cruz J, Gennarelli TA, Alves WM (1992) Continuous monitoring of cerebral oxygenation in acute brain injury: multivariate assessment of severe intracranial \u201cplateau\u201d wave. Case report. J Trauma 32: 401\u2013403","journal-title":"J Trauma"},{"key":"BF01420306_CR14","first-page":"55","volume-title":"Neurotrauma 1. Treatment, rehabilitation and related issues","author":"J Cruz","year":"1986","unstructured":"Cruz J, Mine ME (1986) Modulating cerebral oxygen delivery and extraction in acute traumatic coma. In: Miner MEet al (eds) Neurotrauma 1. Treatment, rehabilitation and related issues. Butterworths, Boston, pp 55\u201372"},{"key":"BF01420306_CR15","doi-asserted-by":"crossref","first-page":"725","DOI":"10.3171\/jns.1990.73.5.0725","volume":"73","author":"J Cruz","year":"1990","unstructured":"Cruz J, Miner ME, Allen SJ, Alves WM, Gennarelli TA (1990) Continuous monitoring of cerebral oxygenation in acute brain injury: injection of mannitol during hyperventilation. J Neurosurg 73: 725\u2013730","journal-title":"J Neurosurg"},{"key":"BF01420306_CR16","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1097\/00003246-199308000-00027","volume":"21","author":"J Cruz","year":"1993","unstructured":"Cruz J, Raps EC, Hoffstad OJ, Jaggi JL, Gennarelli TA (1993) Cerebral oxygenation monitoring. Crit Care Med 21: 1242\u20131246","journal-title":"Crit Care Med"},{"key":"BF01420306_CR17","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1212\/WNL.33.4.391","volume":"33","author":"SM Davis","year":"1983","unstructured":"Davis SM, Ackerman RH, Correia JA, Alpert NM, Chang J, Buonanno F, Kelley RE, Rosner B, Taveras JM (1983) Cerebral blood flow and cerebrovascular CO2-reactivity in strokeage normal controls. Neurology (Cleveland) 33: 391\u2013399","journal-title":"Neurology (Cleveland)"},{"key":"BF01420306_CR18","first-page":"553","volume-title":"Cerebral blood flow and metabolism","author":"L Edvinsson","year":"1993","unstructured":"Edvinsson L, MacKenzie ET, McCulloch J (1993) Autoregulation. Arterial and intracranial pressure. In: Edvinssonet al (eds) Cerebral blood flow and metabolism. Raven, New York, pp 553\u2013580"},{"key":"BF01420306_CR19","first-page":"3","volume-title":"Cerebral blood flow and metabolism","author":"L Edvinsson","year":"1993","unstructured":"Edvinsson L, MacKenzie ET, McCulloch J (1993) General and comparative anatomy of the cerebral circulation. In: Edwinsson Let al (eds) Cerebral blood flow and metabolism. Raven, New York, pp 3\u201339"},{"key":"BF01420306_CR20","first-page":"524","volume-title":"Cerebral blood flow and metabolism","author":"L Edvinsson","year":"1993","unstructured":"Edvinsson L, MacKenzie ET, McCulloch J (1993) Changes in arterial gas tensions. In: Edvinsson Let al (eds) Cerebral blood flow and metabolism. Raven, New York, pp 524\u2013552"},{"key":"BF01420306_CR21","volume-title":"Cerebral blood flow and metabolism","author":"L Edvinsson","year":"1993","unstructured":"Edvinsson L, MacKenzie ET, McCulloch J (1993) Disturbed cerebral autoregulation. In: Edvinsson Let al (eds) Cerebral blood flow and metabolism. Raven, New York"},{"key":"BF01420306_CR22","first-page":"698","volume":"48","author":"EM Enevoldsens","year":"1978","unstructured":"Enevoldsens EM, Jensen FT (1978) Autoregulation and CO2 responses of cerebral blood flow in patients with acute severe head injury. J Neurosurg 48: 698\u2013703","journal-title":"J Neurosurg"},{"key":"BF01420306_CR23","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1136\/jnnp.37.12.1378","volume":"37","author":"C Fieschi","year":"1974","unstructured":"Fieschi C, Battistini N, Beduschi A, Boselli L, Rossanda M (1974) Regional cerebral blood flow and intraventricular pressure in acute head injuries. J Neurol Neurosurg Psychiatry 37: 1378\u20131388","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"BF01420306_CR24","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/978-3-642-73987-3_31","volume-title":"Intracranial pressure VII","author":"MG Goetting","year":"1989","unstructured":"Goetting MG, Preston G (1989) Jugular bulb catheterization in children. In: Hoff JTet al (eds) Intracranial pressure VII. Springer, Berlin Heidelberg New York Tokyo, pp 119\u2013120"},{"key":"BF01420306_CR25","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1007\/978-3-642-73987-3_30","volume-title":"Intracranial pressure VII","author":"MG Goetting","year":"1989","unstructured":"Goetting MG, Preston G (1989) Effect of jugular bulb catheterization on intracranial pressure. In: Hoffet al (eds) Intracranial pressure VII. Springer, Berlin Heidelberg New York Tokyo, pp 116\u2013118"},{"key":"BF01420306_CR26","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1097\/00003246-199011000-00006","volume":"18","author":"MG Goetting","year":"1990","unstructured":"Goetting MG, Preston G (1990) Jugular bulb catheterization: experience with 123 patients. Crit Care Med 18: 1220\u20131223","journal-title":"Crit Care Med"},{"key":"BF01420306_CR27","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1161\/01.STR.5.5.630","volume":"5","author":"RLJ Grubb","year":"1974","unstructured":"Grubb RLJ, Raichle ME, Eichung JO (1974) The effects of changes in PaCO2 on cerebral blood flow, and vascular mean transit time. Stroke 5: 630\u2013639","journal-title":"Stroke"},{"key":"BF01420306_CR28","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1136\/jnnp.29.5.398","volume":"29","author":"AM Harper","year":"1966","unstructured":"Harper AM (1966) Autoregulation of cerebral blood flow: influence of the arterial blood pressure on the blood flow through the cerebral cortex. J Neurol Neurosurg Psychiatry 29: 398\u2013403","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"BF01420306_CR29","doi-asserted-by":"crossref","first-page":"176","DOI":"10.3171\/jns.1990.72.2.0176","volume":"72","author":"JL Jaggi","year":"1990","unstructured":"Jaggi JL, Obrist WD, Gennarelli TA, Eangfitt TW (1990) Relationship of early cerebral blood flow and metabolism to outcome in acute head injury. J Neurosurg 72: 176\u2013182","journal-title":"J Neurosurg"},{"key":"BF01420306_CR30","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1152\/ajplegacy.1945.143.1.53","volume":"143","author":"SS Kety","year":"1945","unstructured":"Kety SS, Schmidt CF, (1945) The determination of cerebral blood flow in man by the use of nitrous oxide in low concentrations. Am J Physiol 143: 53\u201366","journal-title":"Am J Physiol"},{"key":"BF01420306_CR31","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1172\/JCI101680","volume":"25","author":"SS Kety","year":"1948","unstructured":"Kety SS, Schmidt CF (1948) The effects of active and passive hyperventilation on cerebral blood flow, cerebral oxygen consumption, and blood pressure of normal young men. J Clin Invest 25: 107\u2013119","journal-title":"J Clin Invest"},{"key":"BF01420306_CR32","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1172\/JCI101995","volume":"27","author":"SS Kety","year":"1948","unstructured":"Kety SS, Schmidt CF (1948) Effects of altered arterial tensions of carbon dioxide and oxygen on cerebral blood flow and cerebral oxygen consumption of normal young men. J Clin Invest 27: 484\u2013492","journal-title":"J Clin Invest"},{"key":"BF01420306_CR33","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1172\/JCI101994","volume":"27","author":"SS Kety","year":"1948","unstructured":"Kety SS, Schmidt CF (1948) The nitrous oxide method for the quantitative determination of cerebral blood flow in man: theory, procedure and normal values. J Clin Invest 27: 476\u2013483","journal-title":"J Clin Invest"},{"key":"BF01420306_CR34","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/S0003-4975(10)60353-0","volume":"40","author":"T Lundar","year":"1985","unstructured":"Lundar T, Lindegaard KF, Froysaker T, Aaslid R, Grip A, Nornes H (1985) Dissociation between cerebral autoregulation and carbon dioxide reactivity during nonpulsatile cardiopulmonary bypass. Annals Thorac Surg 40: 582\u2013587","journal-title":"Annals Thorac Surg"},{"key":"BF01420306_CR35","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1007\/BF01809461","volume":"106","author":"FF Madsen","year":"1990","unstructured":"Madsen FF (1990) Changes of regional cerebral blood flow after hyperventilation in the pig with an induced focal cerebral contusion. Acta Neurochir (Wien) 106: 164\u2013169","journal-title":"Acta Neurochir (Wien)"},{"key":"BF01420306_CR36","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1227\/00006123-199112000-00011","volume":"29","author":"DW Marion","year":"1991","unstructured":"Marion DW, Bouma GJ (1991) The use of stable xenonenhanced computed tomographic studies of cerebral blood flow to define changes in cerebral carbon dioxide vasoresponsivity caused by a severe head injury. Neurosurgery 29: 869\u2013873","journal-title":"Neurosurgery"},{"key":"BF01420306_CR37","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3171\/sup.1991.75.1s.0s21","volume":"75","author":"A Marmarou","year":"1991","unstructured":"Marmarou A, Anderson RL, Ward JD, Choi SC, Young HF, Eisenberg HM, Foulkes MA, Marshall LF, Janes JA (1991) NINDS traumatic coma data bank: intracranial pressure monitoring methodology. J Neurosurg [Suppl] 75: 21\u201327","journal-title":"J Neurosurg [Suppl]"},{"key":"BF01420306_CR38","doi-asserted-by":"crossref","first-page":"883","DOI":"10.3171\/jns.1987.66.6.0883","volume":"66","author":"A Marmarou","year":"1987","unstructured":"Marmarou A, Maset AL, Ward JD, Choi S, Brooks D, Lutz HA, Moulton RJ, Muizelaar JP, DeSalles A, Young HF (1987) Contribution of CSF and vascular factors to elevation of ICP inseverely head-injured patients. J Neurosurg 66: 883\u2013890","journal-title":"J Neurosurg"},{"key":"BF01420306_CR39","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1007\/978-3-642-73987-3_179","volume-title":"Intracranial pressure VII","author":"A Marmarou","year":"1989","unstructured":"Marmarou A, Wachi A (1989) Blood volume responsivity to ICP change in head injured patients. In: Hoff JTet al (eds) Intracranial pressure VII. Springer, Berlin Heidelberg New York Tokyo, pp 688\u2013690"},{"key":"BF01420306_CR40","doi-asserted-by":"crossref","first-page":"832","DOI":"10.3171\/jns.1987.67.6.0832","volume":"67","author":"AL Maset","year":"1987","unstructured":"Maset AL, Marmarou A, Ward JD, Choi S, Lutz HA, Brooks D, Moulton RJ, DeSalles A, Muizelaar JP, Turner H, Young HF (1987) Pressure-volume index in head injpry. J Neurosurg 67: 832\u2013840","journal-title":"J Neurosurg"},{"key":"BF01420306_CR41","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1001\/archneur.1965.00460270046006","volume":"12","author":"LCJ McHenry","year":"1965","unstructured":"McHenry LCJ, Slocum HC, Bivens HE, Mayes HA, Hayes GJ (1965) Hyperventilation in awake and anesthetized man. Effects on cerebral blood flow and cerebral metabolism. Arch Neurol 12: 270\u2013277","journal-title":"Arch Neurol"},{"key":"BF01420306_CR42","first-page":"223","volume":"89","author":"LCJ McHenry","year":"1964","unstructured":"McHenry LCJ, Slocum HC, Hayes GJ (1964) The effects of hyperventilation on the cerebral circulation and metabolism. Trans Ann Neurol Assoc 89: 223\u2013225","journal-title":"Trans Ann Neurol Assoc"},{"key":"BF01420306_CR43","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1111\/j.1365-2044.1992.tb03142.x","volume":"47","author":"FM Messahel","year":"1992","unstructured":"Messahel FM, Al-Mazroa AA (1992) Cannulation of the internal jugular vein. The very high approach. Anesthesia 47: 842\u2013844","journal-title":"Anesthesia"},{"key":"BF01420306_CR44","first-page":"5","volume-title":"Measuring ICP in patients \u2014 its value now and in the future?","author":"JD Miller","year":"1989","unstructured":"Miller JD (1989) Measuring ICP in patients \u2014 its value now and in the future? In: Hoff JTet al (eds) Springer, Berlin Heidelberg New York Tokyo, pp 5\u201315"},{"key":"BF01420306_CR45","first-page":"507","volume-title":"Textbook of head injury","author":"JD Miller","year":"1989","unstructured":"Miller JD (1989) Pathophysiology of human head injury. In: Becker DPet al (eds) Textbook of head injury. Saunders, Philadelphia, pp 507\u2013524"},{"key":"BF01420306_CR46","first-page":"28","volume":"2","author":"JD Miller","year":"1992","unstructured":"Miller JD (1992) Evaluation and treatment of head injury in adults. Neurosurg Quart 2: 28\u201343","journal-title":"Neurosurg Quart"},{"key":"BF01420306_CR47","first-page":"331","volume-title":"Head injury","author":"JD Miller","year":"1993","unstructured":"Miller JD (1993) Traumatic brain swelling and edema. In: Cooper PR (ed) Head injury. Williams and Wilkins, Baltimore, pp 331\u2013354"},{"key":"BF01420306_CR48","first-page":"221","volume-title":"Textbook of head injury","author":"JP Muizelaar","year":"1989","unstructured":"Muizelaar JP (1989) Cerebral blood flow, cerebral blood volume, and cerebral metabolism after severe head injury. In: Becker DPet al (eds) Textbook of head injury. Saunders, Philadelphia, pp 221\u2013240"},{"key":"BF01420306_CR49","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1007\/978-3-642-73987-3_132","volume-title":"Intracranial pressure VII","author":"JP Muizelaar","year":"1989","unstructured":"Muizelaar JP (1989) Induced arterial hypertension in the treatment of high ICP. In: Hoff JTet al (eds) Intracranial pressure VII. Springer, Berlin Heidelberg New York Tokyo, pp 508\u2013510"},{"key":"BF01420306_CR50","first-page":"91","volume-title":"Trauma of the central nervous system","author":"JP Muizelaar","year":"1985","unstructured":"Muizelaar JP, Becker DP, Lutz HA (1985) Present application and future promise of cerebral blood flow monitoring in head injury. In: Dacey Jr (ed) Trauma of the central nervous system. Raven, New York, pp 91\u2013102"},{"key":"BF01420306_CR51","doi-asserted-by":"crossref","first-page":"63","DOI":"10.3171\/jns.1989.71.1.0063","volume":"71","author":"JP Muizelaar","year":"1989","unstructured":"Muizelaar JP, Marmarou A, DeSalles AAF, Ward JD, Zimmerman RS, Li Z, Choi SC, Young HF (1989) Cerebral blood flow and metabolism in severely head-injury children. Part 1: relationship with GCS score, outcome, ICP and PVI. J Neurosurg 71: 63\u201371","journal-title":"J Neurosurg"},{"key":"BF01420306_CR52","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3171\/jns.1989.71.1.0072","volume":"71","author":"JP Muizelaar","year":"1989","unstructured":"Muizelaar JP, Ward JD, Marmarou A, Newlon PG, Wachi A (1989) Cerebral blood flow and metabolism in severely headinjured children. Part 2: autoregulation. J Neurosurg 71: 72\u201376","journal-title":"J Neurosurg"},{"key":"BF01420306_CR53","doi-asserted-by":"crossref","first-page":"241","DOI":"10.3171\/jns.1984.61.2.0241","volume":"61","author":"WD Obrist","year":"1984","unstructured":"Obrist WD, Eangfitt TW, Jaggi JL, Cruz J, Gennarelli TA (1984) Cerebral blood flow and metabolism in comatose patients with acute head injury. Relationship to intracranial hypertension. J Neurosurg 61: 241\u2013253","journal-title":"J Neurosurg"},{"key":"BF01420306_CR54","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1097\/00000542-199310000-00006","volume":"79","author":"KS Olsen","year":"1993","unstructured":"Olsen KS, Videbaek C, Agerlin N, Kroll M, Bogerasmussen T, Paulson OB, Gjerris F (1993) The effect of tirilazad mesylate (u74006f) on cerebral oxygen consumption, and reactivity of cerebral blood flow to carbon dioxide in healthy volunteers. Anesthesiology 79: 666\u2013671","journal-title":"Anesthesiology"},{"key":"BF01420306_CR55","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1212\/WNL.22.3.286","volume":"22","author":"OB Paulson","year":"1972","unstructured":"Paulson OB, Olesen J, Christensen MS (1972) Restoration of autoregulation of cerebral blood flow by hypocapnia. Neurology (Minneap) 22: 286\u2013293 (Abstract)","journal-title":"Neurology (Minneap)"},{"key":"BF01420306_CR56","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/0002-9149(89)90396-2","volume":"63","author":"OB Paulson","year":"1989","unstructured":"Paulson OB, Waldemar G, Schmidt JF, Strandgaard S (1989) Cerebral circulation under normal and pathologic conditions. Am J Cardiol 63: 26\u201356","journal-title":"Am J Cardiol"},{"key":"BF01420306_CR57","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1152\/ajplegacy.1964.206.1.25","volume":"206","author":"M Reivich","year":"1964","unstructured":"Reivich M (1964) Arterial PCO2 and cerebral hemodynamics. Am J Physiol 206: 25\u201335","journal-title":"Am J Physiol"},{"key":"BF01420306_CR58","doi-asserted-by":"crossref","first-page":"361","DOI":"10.3171\/jns.1987.67.3.0361","volume":"67","author":"CS Robertson","year":"1987","unstructured":"Robertson CS, Grossman RG, Goodman JC, Narayan RK (1987) The predictive value of cerebral anaerobic metabolism with cerebral infarction after head injury. J Neurosurg 67: 361\u2013368","journal-title":"J Neurosurg"},{"key":"BF01420306_CR59","doi-asserted-by":"crossref","first-page":"222","DOI":"10.3171\/jns.1989.70.2.0222","volume":"70","author":"CS Robertson","year":"1989","unstructured":"Robertson CS, Narayan RK, Gokaslan ZL, Pahwa R, Grossman RG, Caram P, Allen E (1989) Cerebral arteriovenous oxygen difference as an estimate of cerebral blood flow in comatose patients. J Neurosurg 70: 222\u2013230","journal-title":"J Neurosurg"},{"key":"BF01420306_CR60","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/BF00304204","volume":"7","author":"P Sanker","year":"1991","unstructured":"Sanker P, Richard KE, Weigl HC, Klug N, van Leyen K (1991) Transcranial Doppler sonography and intracranial pressure monitoring in children and juveniles with acute brain injuries or hydrocephalus. Childs Nerv Syst 7: 391\u2013393","journal-title":"Childs Nerv Syst"},{"key":"BF01420306_CR61","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1097\/00005344-199006000-00017","volume":"15","author":"JF Schmidt","year":"1990","unstructured":"Schmidt JF, Waldemar G, Vorstrup S, Andersen AR, Gjerris F, Paulson OB (1990) Computerized analysis of cerebral blood flow autoregulation in humans: validation of a method for pharmacologie studies. J Cardiovasc Pharmacol 15: 983\u2013988","journal-title":"J Cardiovasc Pharmacol"},{"key":"BF01420306_CR62","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1001\/archneur.1965.00470020020003","volume":"13","author":"W Shapiro","year":"1965","unstructured":"Shapiro W, Wasserman AJ, Patterson JL, Jr (1965) Human cerebrovascular response time to elevation of arterial carbon dioxide tension. Arch Neurol 13: 130\u2013138","journal-title":"Arch Neurol"},{"key":"BF01420306_CR63","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1136\/jnnp.1.3.226","volume":"1","author":"GE Smyth","year":"1938","unstructured":"Smyth GE, Henderson WR (1938) Observations on the cerebrospinal fluid pressure on simultaneous ventricular and lumbar punctures. J Neurol Psychiatry 1: 226\u2013237","journal-title":"J Neurol Psychiatry"},{"key":"BF01420306_CR64","first-page":"772","volume":"33","author":"RF Spetzler","year":"1993","unstructured":"Spetzler RF, Hamilton MG (1993) Pressure autoregulation is intact after arteriovenous malformation resection (letter). Neurosurgery 33: 772\u2013773","journal-title":"Neurosurgery"},{"key":"BF01420306_CR65","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1161\/01.STR.15.3.413","volume":"15","author":"S Strandgaard","year":"1984","unstructured":"Strandgaard S, Paulson OB (1984) Cerebral autoregulation. Stroke 15: 413\u2013416","journal-title":"Stroke"},{"key":"BF01420306_CR66","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/BF01842829","volume":"104","author":"H Tenjun","year":"1990","unstructured":"Tenjun H, Yamaki T, Nakagawa Y, Kuboyama T, Ebisu T, Kobori N, Ueda S, Mizukawa N (1990) Impairment of CO2 reactivity in severe head injury patients: an investigation using thermal diffusion method. Acta Neurochir (Wien) 104: 121\u2013125","journal-title":"Acta Neurochir (Wien)"},{"key":"BF01420306_CR67","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1172\/JCI104359","volume":"40","author":"AJ Wasserman","year":"1961","unstructured":"Wasserman AJ, Patterson JL, Jr (1961) The cerebral vascular response to reduction in arterial carbon dioxide tension. J Clin Invest 40: 1297\u20131303","journal-title":"J Clin Invest"}],"container-title":["Acta Neurochirurgica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01420306.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/BF01420306\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01420306","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01420306.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T01:41:44Z","timestamp":1744162904000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/BF01420306"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,4]]},"references-count":67,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1996,4]]}},"alternative-id":["BF01420306"],"URL":"https:\/\/doi.org\/10.1007\/bf01420306","relation":{},"ISSN":["0001-6268","0942-0940"],"issn-type":[{"value":"0001-6268","type":"print"},{"value":"0942-0940","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,4]]}}}