{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T22:02:02Z","timestamp":1698444122769},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[1994,7,1]],"date-time":"1994-07-01T00:00:00Z","timestamp":773020800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Immunol"],"published-print":{"date-parts":[[1994,7]]},"DOI":"10.1007\/bf01552309","type":"journal-article","created":{"date-parts":[[2005,4,21]],"date-time":"2005-04-21T00:11:13Z","timestamp":1114042273000},"page":"229-236","source":"Crossref","is-referenced-by-count":23,"title":["Salivary defense factors and oral health in patients with common variable immunodeficiency"],"prefix":"10.1007","volume":"14","author":[{"given":"V.","family":"Kirstil\ufffd","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Tenovuo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Ruuskanen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Nikoskelainen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Irjala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Vilja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","first-page":"71","volume":"79","author":"P Brandtzaeg","year":"1983","unstructured":"Brandtzaeg P: The oral secretory immune system with special emphasis on its relation to dental caries. Proc Finn Dent Soc 79:71?84, 1983","journal-title":"Proc Finn Dent Soc"},{"key":"CR2","first-page":"55","volume-title":"Human Saliva: Clinical Chemistry and Microbiology, Vol II","author":"J Tenovuo","year":"1989","unstructured":"Tenovuo J: Nonimmunoglobulin defense factors in human saliva.In Human Saliva: Clinical Chemistry and Microbiology, Vol II, J Tenovuo (ed). Boca Raton, FL, CRC Press, 1989, pp 55?91"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1146\/annurev.mi.35.100181.003115","volume":"35","author":"JR McGhee","year":"1981","unstructured":"McGhee JR, Michalek SM: Immunobiology of dental caries: microbial aspects and local immunity. Annu Rev Microbiol 35:595?638, 1981","journal-title":"Annu Rev Microbiol"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1128\/IAI.43.1.308-313.1984","volume":"43","author":"O-P Lehtonen","year":"1984","unstructured":"Lehtonen O-P, Gr\u00e5hn E, St\u00e5hlberg T, Laitinen LA: Amount and avidity of salivary and serum antibodies againstStreptococcus mutans in two groups of human subjects with different dental caries susceptibility. Infect Immun 43:308?313, 1984","journal-title":"Infect Immun"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/BF00915169","volume":"5","author":"RL Gregory","year":"1985","unstructured":"Gregory RL, Michalek SM, Filler SJ, Mestecky J, McGhee JR: Prevention ofStreptococcus mutans colonization by salivary IgA antibodies. J Clin Immunol 5:55?62, 1985","journal-title":"J Clin Immunol"},{"key":"CR6","first-page":"85","volume":"20","author":"J Tenovuo","year":"1992","unstructured":"Tenovuo J, Jentsch H, Soukka T, Karhuvaara L: Antimicrobial factors of saliva in relation to dental caries and salivary levels of mutans streptococci. J Biol Buccale 20:85?90, 1992","journal-title":"J Biol Buccale"},{"key":"CR7","first-page":"216","volume":"9","author":"GR Riviere","year":"1987","unstructured":"Riviere GR, Papagiannoulis L: Antibodies to indigenous and laboratory strains ofStreptococcus mutans in saliva from children with dental caries and from caries-free children. Pediatr Dent 9:216?220, 1987","journal-title":"Pediatr Dent"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3109\/00016358809004749","volume":"46","author":"E Gr\u00e5hn","year":"1988","unstructured":"Gr\u00e5hn E, Tenovuo J, Lehtonen O-P, Eerola E, Vilja P: Antimicrobial systems of human whole saliva in relation to dental caries, cariogenic bacteria, and gingival inflammation in young adults. Acta Odontol Scand 46:67?74, 1988","journal-title":"Acta Odontol Scand"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"3597","DOI":"10.1128\/IAI.61.9.3597-3604.1993","volume":"61","author":"H Hocini","year":"1993","unstructured":"Hocini H, Iscaki S, Bouvet J-P, Pillot J: Unexpectedly high levels of some presumably protective secretory immunoglobulin A antibodies to dental plaque bacteria in salivas of both caries-resistant and caries-susceptible subjects. Infect Immun 61:3597?3604, 1993","journal-title":"Infect Immun"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/0003-9969(78)90109-7","volume":"23","author":"T Lehner","year":"1978","unstructured":"Lehner T, Murray JJ, Winter GB, Caldwell J: Antibodies toStreptococcus mutans and immunoglobulin levels in children with dental caries. Arch Oral Biol 23:1061?1067, 1978","journal-title":"Arch Oral Biol"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/0003-9969(85)90006-8","volume":"30","author":"AS Aaltonen","year":"1985","unstructured":"Aaltonen AS, Tenovuo J, Lehtonen O-P, Saksala R, Meurman O: Serum antibodies against oralStreptococcus mutans in young children in relation to dental caries and maternal close-contacts. Arch Oral Biol 30:331?335, 1985","journal-title":"Arch Oral Biol"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1159\/000261240","volume":"24","author":"J Tenovuo","year":"1990","unstructured":"Tenovuo J, Lehtonen O-P, Aaltonen AS: Caries development in children in relation to the presence of mutans streptococci in dental plaque and of serum antibodies against whole cells and protein antigen I\/II ofStreptococcus mutans. Caries Res 24:59?64, 1990","journal-title":"Caries Res"},{"key":"CR13","first-page":"382","volume-title":"Markers of High and Low Risk Groups and Individuals. Dental Caries, Vol I","author":"J Tenovuo","year":"1991","unstructured":"Tenovuo J, Lumikari M: Organic factors in human saliva in relation to dental caries.In Markers of High and Low Risk Groups and Individuals. Dental Caries, Vol I, NW Johnson (ed). Cambridge, Cambridge University Press, 1991, pp 382?399"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/0003-9969(91)90142-H","volume":"36","author":"JD Rudney","year":"1991","unstructured":"Rudney JD, Krig MA, Neuvar EK, Soberay AH, Iverson L: Antimicrobial proteins in human unstimulated whole saliva in relation to each other, and to measures of health status, dental plaque accumulation and composition. Arch Oral Biol 36:497?506, 1991","journal-title":"Arch Oral Biol"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/0003-9969(93)90208-4","volume":"38","author":"JD Rudney","year":"1993","unstructured":"Rudney JD, Krig MA, Neuvar EK: Longitudinal study of relations between human salivary antimicrobial proteins and measures of dental plaque accumulation and composition. Arch Oral Biol 38:377?386, 1993","journal-title":"Arch Oral Biol"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1111\/j.1600-0765.1993.tb01060.x","volume":"28","author":"RA Jalil","year":"1993","unstructured":"Jalil RA, Ashley FP, Wilson RF, Wagaiyu EG: Concentrations of thiocyanate, hypothiocyanite, ?free? and ?total? lysozyme, lactoferrin and secretory IgA in resting and stimulated whole saliva of children aged 12?14 years and the relationship with plaque accumulation and gingivitis. J Periodont Res 28:130?136, 1993","journal-title":"J Periodont Res"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1177\/00220345770560030201","volume":"56","author":"MF Cole","year":"1977","unstructured":"Cole MF, Arnold RR, Rhodes MJ, McGhee JR: Immune dysfunction and dental caries. A preliminary report. J Dent Res 56:198?204, 1977","journal-title":"J Dent Res"},{"key":"CR18","first-page":"449","volume-title":"Proceedings, ?Saliva and Dental Caries","author":"RR Arnold","year":"1979","unstructured":"Arnold RR, Pruitt KM, Cole MF, Adamson JM, McGhee JRM: Salivary antibacterial mechanisms in immunodeficiency.In Proceedings, ?Saliva and Dental Caries,? I Kleinberg, SA Ellison, ID Mandel (eds). New York, Spec Suppl Microbiol Abstr, Information Retrieval, 1979, pp 449?462"},{"key":"CR19","first-page":"159","volume-title":"The Borderland Between Caries and Periodontal Disease","author":"D Bratthall","year":"1980","unstructured":"Bratthall D, Bj\u00f6rkander J: Bacteria and oral fluid components: Report of the oral condition in hypogammaglobulinaemic patients.In The Borderland Between Caries and Periodontal Disease, 2nd ed, T Lehner, G Cimasoni (eds). London, Academic Press, 1980, pp 159?173","edition":"2nd ed"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/0003-9969(81)90150-3","volume":"26","author":"DW Legler","year":"1981","unstructured":"Legler DW, McGhee JR, Lynch DP, Mestecky JF, Schaeffer ME, Carson J, Bradley EL Jr: Immunodeficiency disease and dental caries in man. Arch Oral Biol 26:905?910, 1981","journal-title":"Arch Oral Biol"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"803","DOI":"10.14219\/jada.archive.1982.0472","volume":"105","author":"DW Legler","year":"1982","unstructured":"Legler DW, Arnold RR, Lynch DP, McGhee JR: Immunodeficiency disease and implications for dental treatment. J Am Dent Assoc 105:803?808, 1982","journal-title":"J Am Dent Assoc"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/j.1600-0765.1978.tb00152.x","volume":"13","author":"PB Robertson","year":"1978","unstructured":"Robertson PB, Wright TE, Madder BF, Lenertz DM, Levy BM: Periodontal status of patients with abnormalities of the immune system. J Periodont Res 13:37?45, 1978","journal-title":"J Periodont Res"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1902\/jop.1980.51.2.70","volume":"51","author":"PB Robertson","year":"1980","unstructured":"Robertson PB, Mackler BF, Wright TE, Levy BM: Periodontal status of patients with abnormalities of the immune system. II Observations over a 2-year period. J Periodont 51:70?73, 1980","journal-title":"J Periodont"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1902\/jop.1992.63.12.984","volume":"63","author":"G Norhagen Engstr\u00f6m","year":"1992","unstructured":"Norhagen Engstr\u00f6m G, Engstr\u00f6m P-E, Hammarstr\u00f6m L, Smith CIE: Oral conditions in individuals with selective immunoglobulin A deficiency and common variable immunodeficiency. J Periodontol 63:984?989, 1992","journal-title":"J Periodontol"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1600-051X.1993.tb01752.x","volume":"20","author":"G Dahlen","year":"1993","unstructured":"Dahlen G, Bj\u00f6rkander J, Gahnberg L, Slots J, Hanson L-\u00c5: Periodontal disease and dental caries in relation to primary IgG subclass and other humoral immunodeficiencies. J Clin periodontol 20:7?13, 1993","journal-title":"J Clin periodontol"},{"key":"CR26","first-page":"55","volume":"28","author":"J Eskola","year":"1989","unstructured":"Eskola J, Savilahti E, Nikoskelainen J, Ruuskanen O: Regulatory T-cell function in primary humoral immunodeficiency states. J Clin Lab Immunol 28:55?60, 1989","journal-title":"J Clin Lab Immunol"},{"key":"CR27","volume-title":"Oral Health Surveys, Basic Methods","author":"World Health Organization","year":"1977","unstructured":"World Health Organization: Oral Health Surveys, Basic Methods. Geneva, WHO, 1977"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3109\/00016356408993968","volume":"22","author":"J Silness","year":"1964","unstructured":"Silness J, L\u00f6e H: Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 22:121?135, 1964","journal-title":"Acta Odontol Scand"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/j.1600-0714.1981.tb01273.x","volume":"10","author":"J Rundegren","year":"1981","unstructured":"Rundegren J, Ericson T: Effect of calcium on reactions between a salivary agglutinin and a serotype c strain ofStreptococcus mutans. J Oral Pathol 10:269?275, 1981","journal-title":"J Oral Pathol"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/j.1432-1033.1977.tb11873.x","volume":"80","author":"TM Aune","year":"1977","unstructured":"Aune TM, Thomas EL: Accumulation of hypothiocyanite ion during peroxidase-catalyzed oxidation of thiocyanate ion. Eur J Biochem 80:209?214, 1977","journal-title":"Eur J Biochem"},{"key":"CR31","first-page":"385","volume":"870","author":"KM Pruitt","year":"1986","unstructured":"Pruitt KM, Tenovuo J, M\u00e5nsson-Rahemtulla B, Harrington P, Baldone DC: Is thiocyanate peroxidation at equilibriumin vivo? Biochem Biophys Acta 870:385?391, 1986","journal-title":"Biochem Biophys Acta"},{"key":"CR32","doi-asserted-by":"crossref","first-page":"5721","DOI":"10.1021\/ja01118a069","volume":"75","author":"RH Betts","year":"1953","unstructured":"Betts RH, Dainton FS: Electron transfer and other processes involved in the spontaneous bleaching of acidified solutions of ferric thiocyanate. J Am Chem Soc 75:5721?5727, 1953","journal-title":"J Am Chem Soc"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/0022-1759(85)90482-X","volume":"76","author":"P Vilja","year":"1985","unstructured":"Vilja P, Krohn K, Tuohimaa P: A rapid and sensitive non-competitive avidin-biotin assay for lactoferrin. J Immunol Meth 76:73?83, 1985","journal-title":"J Immunol Meth"},{"key":"CR34","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0022-1759(91)90154-8","volume":"141","author":"P Vilja","year":"1991","unstructured":"Vilja P, Lumikari M, Tenovuo J, Sievers G, Tuohimaa P: Sensitive immunometric assays for secretory peroxidase and myeloperoxidase in human saliva. J Immunol Meth 141:277?284, 1991","journal-title":"J Immunol Meth"},{"key":"CR35","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1177\/00220345900690121001","volume":"69","author":"B M\u00e5nsson-Rahemtulla","year":"1990","unstructured":"M\u00e5nsson-Rahemtulla B, Rahemtulla F, Humphreys-Beher MG: Human salivary peroxidase and bovine lactoperoxidase are cross-reactive. J Dent Res 69:1839?1846, 1990","journal-title":"J Dent Res"},{"key":"CR36","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/0167-4838(82)90463-0","volume":"709","author":"R Wever","year":"1982","unstructured":"Wever R, Kast WM, Kasinoedin JH, Boelens R: The peroxidation of thiocyanate catalysed by myeloperoxidase and lactoperoxidase. Biochim Biophys Acta 709:212?219, 1982","journal-title":"Biochim Biophys Acta"},{"key":"CR37","first-page":"1","volume-title":"Human Saliva: Clinical Chemistry and Microbiology, Vol II","author":"P Brandtzaeg","year":"1989","unstructured":"Brandtzaeg P: Salivary immunoglobulinsIn Human Saliva: Clinical Chemistry and Microbiology, Vol II, J Tenovuo (ed). Boca Raton FL, CRC Press, 1989, pp 1?54"},{"key":"CR38","first-page":"193","volume":"90","author":"M Maltz","year":"1982","unstructured":"Maltz M, Zickert I: Effect of penicillin onStreptococcus mutans, Streptococcus sanguis and lactobacilli in hamsters and in man. Scand J Dent Res 90:193?197, 1982","journal-title":"Scand J Dent Res"},{"key":"CR39","first-page":"293","volume-title":"Antimicrobials: can they be effective","author":"WJ Loesche","year":"1984","unstructured":"Loesche WJ: Antimicrobials: can they be effective?In Cariology Today, B Guggenheim (ed). Basel, Karger, 1984, pp 293?304"},{"key":"CR40","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1128\/AAC.37.5.1158","volume":"37","author":"H J\u00e4rvinen","year":"1993","unstructured":"J\u00e4rvinen H, Tenovuo J, Huovinen P: In vitro susceptibility ofStreptococcus mutans to chlorhexidine and six other antimicrobial agents. Antimicrob Agents Chemother 37:1158?1159, 1993","journal-title":"Antimicrob Agents Chemother"},{"key":"CR41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1600-051X.1988.tb01549.x","volume":"15","author":"RA Seymour","year":"1988","unstructured":"Seymour RA, Heasman PA: Drugs and the periodontium. J Clin Periodontol 15:1?16, 1988","journal-title":"J Clin Periodontol"},{"key":"CR42","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1128\/JCM.10.4.538-543.1979","volume":"10","author":"LL Bamman","year":"1979","unstructured":"Bamman LL, Gibbons RJ: Immunoglobulin A antibodies reactive withStreptococcus mutans in saliva of adults, children and predentate infants. J Clin Microbiol 10:538?543, 1979","journal-title":"J Clin Microbiol"},{"key":"CR43","first-page":"44","volume-title":"Primary and Secondary Immunodeficiency Disorders","author":"DYM Leung","year":"1984","unstructured":"Leung DYM, Rosen FS, Geha RS: Disorders of immunoglobulin-antibody system.In Primary and Secondary Immunodeficiency Disorders, RK Chandra (ed). New York, Churchill Livingstone, 1984, pp 44?61"},{"key":"CR44","doi-asserted-by":"crossref","first-page":"2344","DOI":"10.1177\/00220345790580120301","volume":"58","author":"LR Brown","year":"1979","unstructured":"Brown LR, Mackler BF, Levy BM, Wright TE, Handler SF, Moylan JS, Perkins DH, Keene HJ: Comparison of the plaque microflora in immunodeficient and immunocompetent dental patients. J Dent Res 58:2344?2352, 1979","journal-title":"J Dent Res"},{"key":"CR45","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1159\/000260614","volume":"16","author":"KM Pruitt","year":"1982","unstructured":"Pruitt KM, Tenovuo J, Fleming W, Adamson M: Limiting factors for the generation of hypothiocyanite ion, an antimicrobial agent, in human saliva. Caries Res 16:315?323, 1982","journal-title":"Caries Res"},{"key":"CR46","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1177\/00220345800590090201","volume":"59","author":"EL Thomas","year":"1980","unstructured":"Thomas EL, Bates KP, Jefferson MM: Hypothiocyanite ion: Detection of the antimicrobial agent in human saliva. J Dent Res 59:1466?1472, 1980","journal-title":"J Dent Res"},{"key":"CR47","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1177\/00220345870660021501","volume":"66","author":"J Tenovuo","year":"1987","unstructured":"Tenovuo J, Gr\u00e5hn E, Lehtonen O-P, Hyypp\u00e4 T, Karhuvaara L, Vilja P: Antimicrobial factors in saliva: Ontogeny and relation to oral health. J Dent Res 66:475?479, 1987","journal-title":"J Dent Res"}],"container-title":["Journal of Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01552309.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01552309\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01552309","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,7]],"date-time":"2020-04-07T01:18:33Z","timestamp":1586222313000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01552309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,7]]},"references-count":47,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1994,7]]}},"alternative-id":["BF01552309"],"URL":"https:\/\/doi.org\/10.1007\/bf01552309","relation":{},"ISSN":["0271-9142","1573-2592"],"issn-type":[{"value":"0271-9142","type":"print"},{"value":"1573-2592","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,7]]}}}