{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T14:25:41Z","timestamp":1756995941460},"reference-count":8,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[1977,5,1]],"date-time":"1977-05-01T00:00:00Z","timestamp":231292800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008392","name":"Sundhed og Sygdom, Det Frie Forskningsr\u00e5d","doi-asserted-by":"publisher","award":["512-4226"],"award-info":[{"award-number":["512-4226"]}],"id":[{"id":"10.13039\/100008392","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1977,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>The role of bile in the pathogenesis of chronic gastric ulcer was studied in 10\u00a0grown\u2010up miniature pigs. After an observation period of 14\u2013186\u00a0days, 4 pigs out of 5 with total diversion of bile into the stomach developed peptic ulcers in the glandular part of the stomach, whereas none of 5 sham operated pigs developed ulcers after an observation period of 150\u2013196\u00a0days. This difference was significant<\/jats:bold> (<jats:italic>p<\/jats:italic>&lt;<jats:bold>0.05). In all 5 pigs with bile diversion the pyloric gland area enlarged at the cost of the fundic gland area, whereas this was not the case in the 5 controls. This difference was also significant<\/jats:bold> (<jats:italic>p<\/jats:italic>&lt;<jats:bold>0.01). There was no significant change in gastric emptying after the operations. It is concluded that bile can cause gastric ulcer in the pig<\/jats:bold>.<\/jats:p>","DOI":"10.1007\/bf01556863","type":"journal-article","created":{"date-parts":[[2005,4,27]],"date-time":"2005-04-27T19:36:52Z","timestamp":1114630612000},"page":"371-377","source":"Crossref","is-referenced-by-count":12,"title":["Bile induced chronic gastric ulcer in swine"],"prefix":"10.1002","volume":"1","author":[{"given":"Mogens","family":"Rokkjaer","sequence":"first","affiliation":[{"name":"Surgical Gastroenterological Dept. L and Institute of Pathological Anatomy University of Aarhus Kommunehospitalet Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helmer","family":"S\u00f8gaard","sequence":"additional","affiliation":[{"name":"Surgical Gastroenterological Dept. L and Institute of Pathological Anatomy University of Aarhus Kommunehospitalet Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aksel","family":"Kruse","sequence":"additional","affiliation":[{"name":"Surgical Gastroenterological Dept. L and Institute of Pathological Anatomy University of Aarhus Kommunehospitalet Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik","family":"Amdrup","sequence":"additional","affiliation":[{"name":"Surgical Gastroenterological Dept. L and Institute of Pathological Anatomy University of Aarhus Kommunehospitalet Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1977,5]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(68)80001-0"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-110-27674"},{"key":"e_1_2_1_4_1","first-page":"21","article-title":"Factors in the pathogenesis of gastric ulcer","volume":"40","author":"Capper W.M.","year":"1967","journal-title":"Ann. R. Coll. Surg. Engl."},{"key":"e_1_2_1_5_1","first-page":"101","article-title":"Some aspects of the pathogenesis and surgical management of peptic ulcers","volume":"34","author":"Du Plessis D.J.","year":"1960","journal-title":"S. Afr. Med. J."},{"issue":"0","key":"e_1_2_1_6_1","first-page":"73","article-title":"Gastric mucosal alterations, benign and malignant","volume":"6","author":"Du Plessis D.J.","year":"1974","journal-title":"Surg. 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