{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T20:27:26Z","timestamp":1773606446774,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"3-4","license":[{"start":{"date-parts":[[1993,9,1]],"date-time":"1993-09-01T00:00:00Z","timestamp":746841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[1993,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We investigated the per\u2010 and postoperative pain\u2010reducing effect of pethidine given intra\u2010articularly (i. art.). Thirty patients subjected to knee joint arthroscopy, diagnostic and surgical procedures, were randomly assigned to one of three groups. Group A consisted of ten patients who received 250\u00a0mg prilocaine +200 \u03bcg adrenaline (i. art.) in a volume of 50\u00a0ml, group B of ten patients who received 200\u00a0mg pethidine (i. art.) in 50\u00a0ml saline, and group C of ten patients who received 200\u00a0mg pethidine +200 \u03bcg adrenaline (i. art.) in 50\u00a0ml saline. During arthroscopy the patients reported on pain intensity and discomfort using visual analogue scales. Ratings were low and did not differ significantly between the three groups. Two of three patients in each group requested additional analgesics or sedatives due to pain and discomfort, but again with no difference between the three groups. Postoperatively all patients rated their pain intensity at rest and during movement (at 0, 1, 2, 3, 4, 5, 6, 12 and 24 h). The patients receiving pethidine (group B) reported significantly less pain at rest and movement than group A patients, in general at 1\u20134 h postoperatively. A significant difference was detected between groups B and C at 4 h postoperatively. Calculating the total sum of pain scores, patients receiving pethidine (group B) reported significantly less pain both at rest and during movement than those receiving prilocaine (group A). Furthermore, patients in group B used significantly less analgesics than those in group A. Adrenaline did not potentiate the effect of pethidine. Reported side effects were mild and did not require clinical action. The present study provides evidence for pethidine as a potential alternative to prilocaine in arthroscopy using local anaesthetic techniques.<\/jats:p>","DOI":"10.1007\/bf01560204","type":"journal-article","created":{"date-parts":[[2005,4,27]],"date-time":"2005-04-27T15:30:43Z","timestamp":1114615843000},"page":"189-194","source":"Crossref","is-referenced-by-count":16,"title":["Is intra\u2010articular pethidine an alternative to local anaesthetics in arthroscopy?"],"prefix":"10.1002","volume":"1","author":[{"given":"A.","family":"Ekblom","sequence":"first","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Anaesthesiology and Intensive Care Karolinska Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Westman","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Anaesthesiology and Intensive Care Karolinska Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"S\u00f6derlund","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Anaesthesiology and Intensive Care Karolinska Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Valentin","sequence":"additional","affiliation":[{"name":"<!--<label>3<\/label>--> Department of Sports Orthopedic Surgery Karolinska Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Eriksson","sequence":"additional","affiliation":[{"name":"<!--<label>3<\/label>--> Department of Sports Orthopedic Surgery Karolinska Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1993,9]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/58.9.1012"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199309000-00010"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1993.tb07008.x"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1983.tb01939.x"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.1989.4.3.135"},{"key":"e_1_2_1_7_2","first-page":"485","article-title":"Action analgesique locale par effet sur les troncs nerveux de la pethidine","volume":"47","author":"Davidas JL","year":"1992","journal-title":"Therapie"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.3928\/0147-7447-19860201-09"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199206000-00008"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/70.1.87"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199208000-00007"},{"key":"e_1_2_1_12_2","unstructured":"LockerB BeguinJ VielpeauC LoyauG ThomassinC BenardM(1988)Arthroscopy of the knee under local anaesthesia \u2014 a 12 year experience (abstract). Third Congress of the European Society of Knee Surgery and Arthroscopy (ESKA) Amsterdam Netherlands pp1\u20132"},{"key":"e_1_2_1_13_2","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1136\/rapm-00115550-199116040-00004","article-title":"The effect of fentanyl, meperidine and diamorphine on nerve conduction in vitro","volume":"16","author":"Power I","year":"1991","journal-title":"Reg Anaesth"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199212000-00015"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199110173251602"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03008225"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/70.1.63"}],"container-title":["Knee Surgery, Sports Traumatology, Arthroscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01560204.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01560204\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/BF01560204","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T09:42:03Z","timestamp":1760866923000},"score":1,"resource":{"primary":{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/10.1007\/BF01560204"}},"subtitle":["A double\u2010blind study comparing prilocaine with pethidine"],"short-title":[],"issued":{"date-parts":[[1993,9]]},"references-count":16,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[1993,9]]}},"alternative-id":["10.1007\/BF01560204"],"URL":"https:\/\/doi.org\/10.1007\/bf01560204","archive":["Portico"],"relation":{},"ISSN":["0942-2056","1433-7347"],"issn-type":[{"value":"0942-2056","type":"print"},{"value":"1433-7347","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,9]]}}}