{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T18:33:58Z","timestamp":1771871638401,"version":"3.50.1"},"reference-count":66,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1996,2,1]],"date-time":"1996-02-01T00:00:00Z","timestamp":823132800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur. J. Clin. Microbiol. Infect. Dis."],"published-print":{"date-parts":[[1996,2]]},"DOI":"10.1007\/bf01591482","type":"journal-article","created":{"date-parts":[[2005,4,28]],"date-time":"2005-04-28T18:44:46Z","timestamp":1114713886000},"page":"107-115","source":"Crossref","is-referenced-by-count":24,"title":["Penicillin tolerance and treatment failure in group A streptococcal pharyngotonsillitis"],"prefix":"10.1007","volume":"15","author":[{"given":"G. J.","family":"Asselt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. P.","family":"Mouton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. P. A.","family":"Boven","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/0736-4679(92)90146-K","volume":"10","author":"RB Vukmir","year":"1992","unstructured":"Vukmir RB: Adult and pediatric pharyngitis: a review. Journal of Emergency Medicine 1992, 10: 607\u2013616.","journal-title":"Journal of Emergency Medicine"},{"issue":"Supplement 2","key":"CR2","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1093\/clinids\/14.Supplement_2.S218","volume":"14","author":"G Peter","year":"1992","unstructured":"Peter G: Streptococcal pharyngitis: current therapy and criteria for evaluation of new agents. Clinical Infectious Diseases 1992, 14, Supplement 2: 218\u2013223.","journal-title":"Clinical Infectious Diseases"},{"issue":"Supplement 3A","key":"CR3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0002-9343(91)90393-C","volume":"91","author":"RC Moellering","year":"1991","unstructured":"Moellering RC: Revolutionary changes in the macrolide and azalide antibiotics. American Journal of Medicine 1991, 91, Supplement 3A: 1\u20134.","journal-title":"American Journal of Medicine"},{"issue":"Supplement 3A","key":"CR4","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0002-9343(91)90397-G","volume":"91","author":"TM Hooton","year":"1991","unstructured":"Hooton TM: A comparison of azithromycin and penicillin V for the treatment of streptococcal pharyngitis. American Journal of Medicine 1991, 91, Supplement 3A: 23\u201326.","journal-title":"American Journal of Medicine"},{"key":"CR5","first-page":"622","volume":"35","author":"CG Schrock","year":"1992","unstructured":"Schrock CG: Clarithromycih vs. penicillin in the treatment of streptococcal pharyngitis. Journal of Family Practice 1992, 35:622\u2013626.","journal-title":"Journal of Family Practice"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S0022-3476(87)80023-9","volume":"110","author":"TD Smith","year":"1987","unstructured":"Smith TD, Huskins WC, Kim KS, Kaplan EL: Efficacy of \u03b2-lactamase-resistant penicillin and influence of penicillin tolerance in eradicating streptococci from the pharynx after failure of penicillin therapy for group A streptococcal pharyngitis. Journal of Pediatrics 1987, 110: 777\u2013782.","journal-title":"Journal of Pediatrics"},{"key":"CR7","first-page":"192","volume":"20","author":"A Kaufhold","year":"1992","unstructured":"Kaufhold A, Podbielski A, K\u00fchnemund O, L\u00fctticken R: Infektionen durchStreptococcus pyogenes: neuere Aspekte zur Diagnostik, Epidemiologie, Klinik und Therapie. Immunit\u00e4t und Infektion 1992, 20: 192\u2013199.","journal-title":"Immunit\u00e4t und Infektion"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1093\/infdis\/159.1.101","volume":"159","author":"EL Kaplan","year":"1989","unstructured":"Kaplan EL, Johnson DR, Cleary PP: Group A streptococcal serotypes isolated from patients and sibling contacts during the resurgence of rheumatic fever in the United States in the mid-1980s. Journal of Infectious Diseases 1989, 159: 101\u2013103.","journal-title":"Journal of Infectious Diseases"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1056\/NEJM199109123251106","volume":"325","author":"AL Bisno","year":"1991","unstructured":"Bisno AL: Group A streptococcal infections and acute rheumatic fever. New England Journal of Medicine 1991, 325: 783\u2013793.","journal-title":"New England Journal of Medicine"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"68","DOI":"10.3109\/00016489209136813","volume":"Supplement 492","author":"A Stjernquist-Desatnik","year":"1992","unstructured":"Stjernquist-Desatnik A, Orrling A, Schal\u00e9n C, Kamme C: Penicillin tolerance in group A streptococci and treatment failure in streptococcal tonsillitis. Acta Oto-Laryngologica 1992, Supplement 492: 68\u201371.","journal-title":"Acta Oto-Laryngologica"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/S0022-3476(85)80392-9","volume":"107","author":"KS Kim","year":"1985","unstructured":"Kim KS, Kaplan EL: Association of penicillin tolerance with failure to eradicate group A streptococci from patients with pharyngitis. Journal of Pediatrics 1985, 107: 681\u2013684.","journal-title":"Journal of Pediatrics"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"357","DOI":"10.3109\/inf.1985.17.issue-3.04","volume":"17","author":"K Roos","year":"1985","unstructured":"Roos K, Holm SE, Ekedahl C: Treatment failure in acute streptococcal tonsillitis in children over the age of 10 and in adults. Scandinavian Journal of Infectious Diseases 1985, 17:357\u2013365.","journal-title":"Scandinavian Journal of Infectious Diseases"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1093\/infdis\/156.3.514","volume":"156","author":"R Dagan","year":"1987","unstructured":"Dagan R, Ferne M, Scheinis M, Alkan M, Katzenelson E: An epidemic of penicillin-tolerant group A streptococcal pharyngitis in children living in a closed community: mass treatment with erythromycin. Journal of Infectious Diseases 1987, 156: 514\u2013516.","journal-title":"Journal of Infectious Diseases"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/S0140-6736(80)91832-2","volume":"ii","author":"AS Gastanaduy","year":"1980","unstructured":"Gastanaduy AS, Kaplan EL, Huwe BB, McKay C, Wannamaker LW: Failure of penicillin to eradicate group A streptococci during an outbreak of pharyngitis. Lancet 1980, ii: 498\u2013502.","journal-title":"Lancet"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1007\/BF01963451","volume":"8","author":"D Milatovic","year":"1989","unstructured":"Milatovic D, Knauer J: Cefadroxil versus penicillin in the treatment of streptococcal tonsillopharyngitis. European Journal of Clinical Microbiology & Infectious Diseases 1989, 8:282\u2013288.","journal-title":"European Journal of Clinical Microbiology & Infectious Diseases"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/S0022-3476(87)80024-0","volume":"110","author":"S Feldman","year":"1987","unstructured":"Feldman S, Bisno AL, Lott L, Dodge R, Jackson RE: Efficacy of benzathine penicillin G in group A streptococcal pharyngitis: reevaluation. Journal of Pediatrics 1987, 110:783\u2013787.","journal-title":"Journal of Pediatrics"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1128\/AAC.37.8.1620","volume":"37","author":"D Milatovic","year":"1993","unstructured":"Milatovic D, Adam D, Hamilton H, Matermen E: Cefprozil versus penicillin V in treatment of streptococcal tonsillopharyngitis. Antimicrobial Agents and Chemotherapy 1993, 37: 1620\u20131623.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/S0022-3476(85)80437-6","volume":"107","author":"I Brook","year":"1985","unstructured":"Brook I: Penicillin V and rifampicin for streptococcal pharyngitis. Journal of Pediatrics 1985, 107: 825\u2013826.","journal-title":"Journal of Pediatrics"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"313","DOI":"10.3109\/00365548609032342","volume":"18","author":"K Roos","year":"1986","unstructured":"Roos K, Grahn E, Holm SA: Evaluation of beta-lactamase activity and microbial interference in treatment failures of acute streptococcal tonsillitis. Scandinavian Journal of Infectious Diseases 1986, 18: 313\u2013319.","journal-title":"Scandinavian Journal of Infectious Diseases"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1093\/clinids\/6.5.601","volume":"6","author":"I Brook","year":"1984","unstructured":"Brook I: The role of \u03b2-lactamase-producing bacteria in the persistence of streptococcal tonsillar infection. Reviews of Infectious Diseases 1984, 6: 601\u2013607.","journal-title":"Reviews of Infectious Diseases"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1080\/00365549309169666","volume":"25","author":"K Roos","year":"1993","unstructured":"Roos K, Holm SA, Grahn E, Lind L: Alpha-streptococci as supplementary treatment of recurrent streptococcal tonsillitis: a randomized placebo controlled study. Scandinavian Journal of Infectious Diseases 1993, 25: 31\u201335.","journal-title":"Scandinavian Journal of Infectious Diseases"},{"key":"CR22","first-page":"443","volume":"i","author":"BJ Wilkinson","year":"1977","unstructured":"Wilkinson BJ: A new type of penicillin resistance ofStaphylococcus aureus. Lancet 1977, i: 443\u2013447.","journal-title":"Lancet"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1128\/AAC.23.1.142","volume":"23","author":"PC Taylor","year":"1983","unstructured":"Taylor PC, Schoenknecht FD, Sherris JC, Linner EC: Determination of minimal bactericidal concentrations of oxacillin forStaphylococcus aureus: influence and significance of technical factors. Antimicrobial Agents and Chemotherapy 1983, 23: 142\u2013150.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"issue":"Supplement A","key":"CR24","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/jac\/20.suppl_A.41","volume":"20","author":"CW Stratton","year":"1987","unstructured":"Stratton CW: The role of the microbiology laboratory in the treatment of infective endocarditis. Journal of Antimicrobial Chemotherapy 1987, 20, Supplement A: 41\u201349.","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"CR25","first-page":"453","volume-title":"Manual of clinical microbiology","author":"JA Washington II","year":"1980","unstructured":"Washington JA II, Sutter VL: Dilution susceptibility test: agar and macro-broth dilution procedures. In: Lenette EH, Balows A, Hausier WJ Jr, Truant JP (ed): Manual of clinical microbiology. American Society for Microbiology, Washington, DC, 1980, p. 453\u2013458."},{"key":"CR26","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1128\/AAC.30.5.633","volume":"30","author":"JC Sherris","year":"1986","unstructured":"Sherris JC: Problems in in vitro determination of antibiotic tolerance in clinical isolates. Antimicrobial Agents and Chemotherapy 1986, 30: 633\u2013637.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"CR27","first-page":"1153","volume-title":"Manual of clinical microbiology","author":"CW Stratton","year":"1991","unstructured":"Stratton CW, Cooksey RC: Susceptibility test: special tests. In: Balows A, Hausier WJ Jr, Herrmann KL, Isenberg HD, Shadomy HJ (ed): Manual of clinical microbiology. American Society for Microbiology, Washington, DC, 1991, p. 1153\u20131165."},{"key":"CR28","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1093\/clinids\/7.3.368","volume":"7","author":"S Handwerger","year":"1985","unstructured":"Handwerger S, Tomasz A: Antibiotic tolerance among clinical isolates of bacteria. Reviews of Infectious Diseases 1985, 7: 368\u2013386.","journal-title":"Reviews of Infectious Diseases"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1099\/00222615-38-3-197","volume":"38","author":"GJ Asselt Van","year":"1993","unstructured":"Van Asselt GJ, Mouton RP: Detection of penicillin tolerance inStreptococcus pyogenes. Journal of Medical Microbiology 1993, 38: 197\u2013202.","journal-title":"Journal of Medical Microbiology"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/BF01965265","volume":"8","author":"MF Michel","year":"1989","unstructured":"Michel MF, Van Leeuwen WB: Degree and stability to penicillin inStreptococcus pyogenes. European Journal of Clinical Microbiology & Infectious Diseases 1989, 8: 225\u2013232.","journal-title":"European Journal of Clinical Microbiology & Infectious Diseases"},{"key":"CR31","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1007\/BF01968144","volume":"8","author":"R Dagan","year":"1989","unstructured":"Dagan R, Ferne M: Association of penicillin-tolerant streptococci with epidemics of streptococcal pharyngitis in closed communities. European Journal of Clinical Microbiology & Infectious Diseases 1989, 8: 629\u2013631.","journal-title":"European Journal of Clinical Microbiology & Infectious Diseases"},{"key":"CR32","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1128\/AAC.25.5.575","volume":"25","author":"WHF Goessens","year":"1984","unstructured":"Goessens WHF, Fontijne P, Van Raffe M, Michel MF: Tolerance percentage as a criterion for the detection of tolerantStaphylococcus aureus strains. Antimicrobial Agents and Chemotherapy 1984, 25: 575\u2013578.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"CR33","first-page":"587","volume":"144","author":"RR Wittler","year":"1990","unstructured":"Wittler RR, Yamada SM, Bass JW, Hamill R, Wiebe RA, Ascher DP: Penicillin tolerance and erythromycin resistance of group A \u03b2-hemolytic streptococci in Hawaii and the Philippines. American Journal of Diseases of Children 1990, 144: 587\u2013589.","journal-title":"American Journal of Diseases of Children"},{"key":"CR34","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1093\/jac\/35.4.555","volume":"35","author":"GJ Asselt Van","year":"1995","unstructured":"Van Asselt GJ, Mouton RP: Low prevalence of penicillin tolerance in group A streptococci. Journal of Antimicrobial Chemotherapy 1995, 35: 555\u2013557.","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"CR35","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/S0022-3476(85)80687-9","volume":"106","author":"S Chaudhary","year":"1985","unstructured":"Chaudhary S, Bilinski SA, Hennessy JL, Soler SM, Wallace SE, Schacht LM, Bisno AI: Penicillin V and rifampin for the treatment of group A streptococcal pharyngitis: a randomized trial of 10 days penicillin vs. 10 days penicillin with rifampin during the final four days of therapy. Journal of Pediatrics 1985, 106: 481\u2013486 and 107: 825\u2013826 (letter).","journal-title":"Journal of Pediatrics"},{"key":"CR36","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1007\/BF02185849","volume":"8","author":"C Betriu","year":"1989","unstructured":"Betriu C, Campos E, Cabronero C, Fernandez A, Picazo JJ, Noriega AR: Penicillin tolerance in group A streptococci. European Journal of Clinical Microbiology & Infectious Diseases 1989, 8: 799\u2013800.","journal-title":"European Journal of Clinical Microbiology & Infectious Diseases"},{"key":"CR37","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0022-3476(78)80603-9","volume":"93","author":"JL Allen","year":"1978","unstructured":"Allen JL, Sprunt K: Discrepancy between minimum inhibitory and minimum bactericidal concentrations of penicillin for group A and group B \u03b2-hemoiytic streptococci. Journal of Pediatrics 1978, 93: 69\u201371.","journal-title":"Journal of Pediatrics"},{"key":"CR38","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/0732-8893(86)90069-6","volume":"4","author":"K Krasinski","year":"1986","unstructured":"Krasinski K, Hanna B, LaRussa P, Desiderio D: Penicillin tolerant group A streptococci. Diagnostic Microbiology and Infectious Disease 1986, 4: 291\u2013297.","journal-title":"Diagnostic Microbiology and Infectious Disease"},{"key":"CR39","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1093\/jac\/33.3.668","volume":"33","author":"MSY Brett","year":"1994","unstructured":"Brett MSY: Antibiotic susceptibilities and penicillin tolerance of group A streptococci isolated in New Zealand in 1990. Journal of Antimicrobial Chemotherapy 1994, 33: 668\u2013689.","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"CR40","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1128\/AAC.30.4.521","volume":"30","author":"E Tuomanen","year":"1986","unstructured":"Tuomanen E, Durack DT, Tomasz A: Antibiotic tolerance among clinical isolates of bacteria. Antimicrobial Agents and Chemotherapy 1986, 30: 521\u2013526.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"CR41","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1093\/infdis\/158.2.487","volume":"158","author":"BF Woolfrey","year":"1988","unstructured":"Woolfrey BF, Lally RT, Gresser-Burns M: Penicillin tolerance in group A streptococci. Journal of Infectious Diseases 1988, 158: 487\u2013488.","journal-title":"Journal of Infectious Diseases"},{"key":"CR42","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1093\/jac\/25.2.209","volume":"25","author":"PA James","year":"1990","unstructured":"James PA: Comparison of four methods for the determination of MIC and MBC of penicillin for viridans streptococci and the implications for penicillin tolerance. Journal of Antimicrobial Chemotherapy 1990, 25: 209\u2013216.","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"CR43","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1128\/AAC.30.5.792","volume":"30","author":"BF Woolfrey","year":"1986","unstructured":"Woolfrey BF, Lally RT, Ederer MN: Influence of technical factor variations during inoculum preparation on the agar dilution plate-count method for quantitation ofStaphylococcus aureus oxacillin persisters. Antimicrobial Agents and Chemotherapy 1986, 30: 792\u2013793.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"CR44","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1128\/AAC.20.1.66","volume":"20","author":"PR Murray","year":"1981","unstructured":"Murray PR, Jorgensen JH: Quantitative susceptibility test methods in major United States medical centers. Antimicrobial Agents and Chemotherapy 1981, 20: 66\u201370.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"CR45","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1128\/AAC.18.5.784","volume":"18","author":"CG Mayhall","year":"1980","unstructured":"Mayhall CG, Apollo E: Effect of storage and changes in bacterial growth phase and antibiotic concentrations on antimicrobial tolerance inStaphylococcus aureus. Antimicrobial Agents and Chemotherapy 1980, 18: 784\u2013788.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"CR46","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1007\/BF01963072","volume":"7","author":"A Str\u00f6mberg","year":"1988","unstructured":"Str\u00f6mberg A, Schwan A, Cars O: Bacteriological and serological aspects of group A streptococcal pharyngotonsillitis caused by group A streptococci. European Journal of Clinical Microbiology & Infectious Diseases 1988, 7:172\u2013174.","journal-title":"European Journal of Clinical Microbiology & Infectious Diseases"},{"key":"CR47","doi-asserted-by":"crossref","first-page":"421","DOI":"10.3109\/00365548709021674","volume":"19","author":"E Grahn","year":"1987","unstructured":"Grahn E, Holm SE, Roos K: Penicillin tolerance in betastreptococci isolated from patients with tonsillitis. Scandinavian Journal of Infectious Diseases 1987, 19: 421\u2013426.","journal-title":"Scandinavian Journal of Infectious Diseases"},{"key":"CR48","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1093\/infdis\/158.2.488","volume":"158","author":"R Dagan","year":"1988","unstructured":"Dagan R, Ferne M: Reply. Journal of Infectious Diseases 1988, 158: 488.","journal-title":"Journal of Infectious Diseases"},{"key":"CR49","first-page":"1105","volume-title":"Manual of clinical microbiology","author":"DF Sahm","year":"1991","unstructured":"Sahm DF, Washington JA II: Antibacterial susceptibility test: dilution methods. In: Balows A, Hausler WJ Jr, Herrmann KL, Isenberg HD, Shadomy HJ (ed): Manual of clinical microbiology. American Society for Microbiology, Washington, DC, 1991, p. 1105\u20131116."},{"key":"CR50","volume-title":"Proposed guidelines M26-P","author":"National Committee for Clinical Laboratory Standards","year":"1987","unstructured":"National Committee for Clinical Laboratory Standards. Methods for determining bactericidal activity of antimicrobial agents. Proposed guidelines M26-P. NCCLS, Villanova, PA, 1987."},{"key":"CR51","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1093\/clinids\/11.3.361","volume":"11","author":"I Brook","year":"1989","unstructured":"Brook I: Inoculum effect. Reviews of Infectious Diseases 1989, 11: 361\u2013368.","journal-title":"Reviews of Infectious Diseases"},{"key":"CR52","volume-title":"Approved standard M7-A2","author":"National Committee for Clinical Laboratory Standards","year":"1990","unstructured":"National Committee for Clinical Laboratory Standards. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Approved standard M7-A2. NCCLS, Villanova, PA, 1990."},{"key":"CR53","volume-title":"Fourth informational supplement M100-S4","author":"National Committee for Clinical Laboratory Standards","year":"1992","unstructured":"National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial susceptibility testing. Fourth informational supplement M100-S4. NCCLS, Villanova, PA, 1992."},{"key":"CR54","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1128\/AAC.11.3.376","volume":"11","author":"G Masuda","year":"1977","unstructured":"Masuda G, Tomioka S, Uchida H, Hasegawa M: Bacteriostatic and bactericidal activities of selected beta-lac tam antibiotics studied on agar plates. Antimicrobial Agents and Chemotherapy 1977, 11: 376\u2013382.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"CR55","first-page":"358","volume-title":"Current clinical topics in infectious diseases","author":"LD Sabath","year":"1983","unstructured":"Sabath LD, Mokhbat JE: What is the clinical significance of tolerance to \u03b2-lactam antibiotics? In: Remington JS, Schwarz MN (ed): Current clinical topics in infectious diseases. McGraw-Hill, New York, 1983, p. 358\u2013377."},{"key":"CR56","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1093\/infdis\/148.3.488","volume":"148","author":"KS Kim","year":"1983","unstructured":"Kim KS, Anthony BF: Use of penicillin-gradient and replicate plates for the demonstration of tolerance to penicillin in streptococci. Journal of Infectious Diseases 1983, 148:488\u2013491.","journal-title":"Journal of Infectious Diseases"},{"key":"CR57","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1128\/JCM.16.4.744-746.1982","volume":"16","author":"J Dankert","year":"1982","unstructured":"Dankert J, Holloway Y, Joldersma W, Hess J: Screening for penicillin tolerance in viridans streptococci by a simple disk method. Journal of Clinical Microbiology 1982, 16: 744\u2013746.","journal-title":"Journal of Clinical Microbiology"},{"key":"CR58","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1136\/jcp.36.12.1353","volume":"36","author":"GJ Slater","year":"1983","unstructured":"Slater GJ, Greenwood D: Detection of penicillin tolerance in streptococci. Journal of Clinical Pathology 1983, 36: 1353\u20131356.","journal-title":"Journal of Clinical Pathology"},{"key":"CR59","volume-title":"Methods for quantitative synthesis in medicine","author":"DB Petitti","year":"1994","unstructured":"Petitti DB: Meta-analysis, decision analysis, and cost-effectiveness analysis. Methods for quantitative synthesis in medicine. Oxford University Press, Oxford, UK, 1994."},{"key":"CR60","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1093\/infdis\/163.3.640","volume":"163","author":"GP Voorn","year":"1991","unstructured":"Voorn GP, Thompson J, Goessens WHF, Schmal-Bauer WC, Broeders PHM: Role of tolerance in cloxacillin treatment of experimentalStaphylococcus aureus endocarditis. Journal of Infectious Diseases 1991, 163: 640\u2013643.","journal-title":"Journal of Infectious Diseases"},{"key":"CR61","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1128\/AAC.23.2.273","volume":"23","author":"RO Brennan","year":"1983","unstructured":"Brennan RO, Durack DT: Therapeutic significance of penicillin tolerance in experimental streptococcal endocarditis. Antimicrobial Agents and Chemotherapy 1983, 23: 273\u2013277.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"CR62","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1128\/AAC.26.6.829","volume":"26","author":"WHF Goessens","year":"1984","unstructured":"Goessens WHF, Fontijne P, Michel MF: Responses of tolerant and nontolerantStaphylococcus aureus strains to methicillin treatment in an experimental infection in mice. Antimicrobial Agents and Chemotherapy 1984, 26: 829\u2013832.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"CR63","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1093\/jac\/11.6.555","volume":"11","author":"J Hess","year":"1983","unstructured":"Hess J, Dankert J, Durack D: Significance of penicillin tolerance in vivo: prevention of experimentalStreptococcus sanguis endocarditis. Journal of Antimicrobial Chemotherapy 1983, 11: 555\u2013564.","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"CR64","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1093\/jac\/25.1.103","volume":"25","author":"J Meeson","year":"1990","unstructured":"Meeson J, McColm AA, Acred P, Greenwood D: Differential response to benzylpenicillin in vivo of tolerant and non-tolerant variants ofStreptococcus sanguis II. Journal of Antimicrobial Chemotherapy 1990, 25: 103\u2013109.","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"CR65","doi-asserted-by":"crossref","first-page":"95","DOI":"10.3109\/00365548909035686","volume":"21","author":"JJ Hoogeterp","year":"1989","unstructured":"Hoogeterp JJ, Mattie H, Krul AM, Terporteren P, Van Furth R: Comparison of in vivo and in vitro activities of antibiotics with different modes of action against a tolerant and non-tolerantStaphylococcus aureus strain. Scandinavian Journal of Infectious Diseases 1989, 21: 95\u2013101.","journal-title":"Scandinavian Journal of Infectious Diseases"},{"key":"CR66","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1128\/AAC.38.3.487","volume":"38","author":"GP Voorn","year":"1994","unstructured":"Voorn GP, Kuyvenhoven J, Goessens WHF, Schmal-Bauer WC, Breeders PHM, Thompson J, Michel MF: Role of tolerance in treatment and prophylaxis of experimentalStaphylococcus aureus endocarditis with vancomycin, teicoplanin, and daptomycin. Antimicrobial Agents and Chemotherapy 1994, 38: 487\u2013493.","journal-title":"Antimicrobial Agents and Chemotherapy"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01591482.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01591482\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01591482","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,7]],"date-time":"2020-04-07T04:15:58Z","timestamp":1586232958000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01591482"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,2]]},"references-count":66,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1996,2]]}},"alternative-id":["BF01591482"],"URL":"https:\/\/doi.org\/10.1007\/bf01591482","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,2]]}}}