{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T14:27:44Z","timestamp":1770215264913,"version":"3.49.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[1992,11,1]],"date-time":"1992-11-01T00:00:00Z","timestamp":720576000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vichows Archiv A Pathol Anat"],"published-print":{"date-parts":[[1992,11]]},"DOI":"10.1007\/bf01606875","type":"journal-article","created":{"date-parts":[[2005,4,29]],"date-time":"2005-04-29T21:03:35Z","timestamp":1114808615000},"page":"467-475","source":"Crossref","is-referenced-by-count":7,"title":["Production of anti-NC1 antibody by affected male dogs with X-linked hereditary nephritis: A probe for assessing the NC1 domain of collagen type IV in dogs and humans with hereditary nephritis"],"prefix":"10.1007","volume":"421","author":[{"given":"Paul S.","family":"Thorner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reuben","family":"Baumal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor E. O.","family":"Valli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Don","family":"Mahuran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula M.","family":"Marrano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Jacobs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","first-page":"617","volume-title":"Strauss and Welt's diseases of the kidney","author":"CL Atkin","year":"1986","unstructured":"Atkin CL, Gregory MC, Broder WA (1986) Alport syndrome. In: Schier RW, Gottschalk CW (eds) Strauss and Welt's diseases of the kidney, 4th edn. Little Brown, Boston, pp 617\u2013641","edition":"4th edn."},{"key":"CR2","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1126\/science.2349482","volume":"248","author":"DF Barker","year":"1990","unstructured":"Barker DF, Hostikka SL, Zhou J, Chow LT, Oliphant AR, Gerken SC, Gregory MC, Skolnick MH, Atkin CL, Tryggvason K (1990) Identification of mutations in the COL4A5 collagen gene in Alport syndrome. Science 248:1224\u20131227","journal-title":"Science"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/S0272-6386(87)80177-4","volume":"10","author":"J Bernstein","year":"1987","unstructured":"Bernstein J (1987) The glomerular basement membrane abnormality in Alport's syndrome. Am J Kidney Dis 10:222\u2013229","journal-title":"Am J Kidney Dis"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"7874","DOI":"10.1016\/S0021-9258(18)47648-X","volume":"262","author":"RJ Butkowski","year":"1987","unstructured":"Butkowski RJ, Langeveld JP, Wieslander J, Hamilton J, Hudson BG (1987) Loalization of the Goodpasture epitope to a novel chain of basement membrane collagen. J Biol Chem 262:7874\u20137877","journal-title":"J Biol Chem"},{"key":"CR5","first-page":"365","volume":"115","author":"RJ Butkowski","year":"1990","unstructured":"Butkowski RJ, Shen G-Q, Wieslander J, Michael AF, Fish AJ (1990) Characterization of type IV collagen NC1 monomers and Goodpasture antigen in human renal basement membranes. J Lab Clin Med 115:365\u2013373","journal-title":"J Lab Clin Med"},{"key":"CR6","first-page":"38","volume":"38","author":"BS Emanuel","year":"1986","unstructured":"Emanuel BS, Sellinger BT, Gudas LJ, Myers JC (1986) Localization of the human procollagen \u03b11(IV) gene to chromosome 13q34 by in situ hybridization. Am J Hum Genet 38:38\u201344","journal-title":"Am J Hum Genet"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1038\/ki.1985.63","volume":"27","author":"J Feingold","year":"1985","unstructured":"Feingold J, Bois E, Chompret A, Broyer M, Gubler M-C, Gr\u00fcnfeld J-P (1985) Genetic heterogeneity of Alport syndrome. Kidney Int 27:672\u2013677","journal-title":"Kidney Int"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1097\/00007890-198812000-00013","volume":"46","author":"SJ Fleming","year":"1988","unstructured":"Fleming SJ, Savage CO, McWilliam LJ, Pickering SJ, Ralston AJ, Johnson RW, Ackrill P (1988) Anti-glomerular basement membrane antibody-mediated nephritis complicating transplantation in a patient with Alport's syndrome. Transplantation 46:857\u2013859","journal-title":"Transplantation"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1073\/pnas.84.2.512","volume":"84","author":"CA Griffin","year":"1987","unstructured":"Griffin CA, Emanuel BS, Hansen JR, Cavenee WK, Myers JC (1987) Human collagen genes encoding basement membrane \u03b11(IV) and \u03b12(IV) chains map to the distal long arm of chromosome 13. Proc Natl Acad Sci USA 84:512\u2013516","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/ki.1985.14","volume":"27","author":"J-P Gr\u00fcnfeld","year":"1985","unstructured":"Gr\u00fcnfeld J-P (1985) The clinical spectrum of hereditary nephritis. Kidney Int 27:83\u201392","journal-title":"Kidney Int"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"19488","DOI":"10.1016\/S0021-9258(19)77660-1","volume":"263","author":"SL Hostikka","year":"1988","unstructured":"Hostikka SL, Tryggvason K (1988) The complete primary structure of the \u03b12 chain of human type IV collagen and comparison with the \u03b11(IV) chain. J Biol Chem 263:19488\u201319493","journal-title":"J Biol Chem"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1073\/pnas.87.4.1606","volume":"87","author":"SL Hostikka","year":"1990","unstructured":"Hostikka SL, Eddy RL, Byers MG, Hoyhtya, Shows TB, Tryggvason K (1990) Identification of a distinct type IV collagen \u03b1 chain with restricted kidney distribution and assignment of its gene to the locus of X chromosome-linked Alport syndrome. Proc Natl Acad Sci USA 87:1606\u20131610","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR13","first-page":"256","volume":"61","author":"BG Hudson","year":"1989","unstructured":"Hudson BG, Wieslander J, Wisdom BJ Jr, Noelken ME (1989) Biology of disease. Goodpasture syndrome: molecular architecture and function of basement membrane antigen. Lab Invest 61:256\u2013269","journal-title":"Lab Invest"},{"key":"CR14","first-page":"536","volume":"125","author":"B Jansen","year":"1986","unstructured":"Jansen B, Thorner P, Baumal R, Valli V, Maxie MG, Singh A (1986a) Samoyed hereditary glomerulopathy (SHG). Evolution of splitting of glomerular capillary basement membranes. Am J Pathol 125:536\u2013545","journal-title":"Am J Pathol"},{"key":"CR15","first-page":"551","volume":"107","author":"B Jansen","year":"1986","unstructured":"Jansen B, Tryphonas L, Wong J, Thorner P, Maxie MG, Valli VE, Baumal R, Basrur PK (1986b) Mode of inheritance of Samoyed hereditary glomerulopathy: an animal model of hereditary nephritis in humans. J Lab Clin Med 107:551\u2013555","journal-title":"J Lab Clin Med"},{"key":"CR16","first-page":"387","volume":"51","author":"B Jansen","year":"1987","unstructured":"Jansen B, Valli VE, Thorner P, Baumal R, Lumsden JH (1987) Samoyed hereditary glomerulopathy: serial, clinical and laboratory (urine, serum biochemistry and hematology) studies. Can J Vet Res 51:387\u2013393","journal-title":"Can J Vet Res"},{"key":"CR17","first-page":"111","volume":"15","author":"EH Jenis","year":"1981","unstructured":"Jenis EH, Valeski JE, Calcagno PL (1981) Variability of anti-GBM binding in hereditary nephritis. Clin Nephrol 15:111\u2013114","journal-title":"Clin Nephrol"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/S0272-6386(83)80043-2","volume":"2","author":"K Jeraj","year":"1983","unstructured":"Jeraj K, Kim Y, Vernier RL, Fish AJ, Michael AF (1983) Absence of Goodpasture's antigen in male patients with familial nephritis. Am J Kidney Dis 2:626\u2013629","journal-title":"Am J Kidney Dis"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1172\/JCI112658","volume":"78","author":"C Kashtan","year":"1986","unstructured":"Kashtan C, Fish AJ, Kleppel M, Yoshioka K, Michael AF (1986) Nephritogenic antigen determinants in epidermal and renal basement membranes of kindreds with Alport-type familial nephritis. J Clin Invest 78:1035\u20131044","journal-title":"J Clin Invest"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1172\/JCI113057","volume":"80","author":"MM Kleppel","year":"1987","unstructured":"Kleppel MM, Kashtan CE, Butkowski RJ, Fish AJ, Michael AF (1987) Alport familial nephritis: absence of 28 kilodalton noncollagenous monomers of type IV collagen in glomerular basement membrane. J Clin Invest 80:263\u2013266","journal-title":"J Clin Invest"},{"key":"CR21","first-page":"278","volume":"61","author":"MM Kleppel","year":"1989","unstructured":"Kleppel MM, Kashtan C, Santi PA, Wieslander J, Michael AF (1989) Distribution of familial nephritis antigen in normal tissue and renal basement membranes of patients with homozygous and heterozygous Alport familial nephritis. Relationship of familial nephritis and Goodpasture antigens to novel collagen chains and type IV collagen. Lab Invest 61:278\u2013289","journal-title":"Lab Invest"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"4137","DOI":"10.1016\/S0021-9258(19)50639-1","volume":"267","author":"MM Kleppel","year":"1992","unstructured":"Kleppel MM, Fan WW, Cheong HI, Michael AF (1992) Evidence for separate networks of classical and novel basement membrane collagen. Characterization of \u03b13(IV)-Alport antigen heterodimer. J Biol Chem 267:4137\u20134142","journal-title":"J Biol Chem"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"10481","DOI":"10.1016\/S0021-9258(19)81541-7","volume":"263","author":"JPM Langeveld","year":"1988","unstructured":"Langeveld JPM, Wieslander J, Timoneda J, McKinney P, Butkowski RJ, Wisdom BJ Jr, Hudson BG (1988) Structural heterogeneity of the non-collagenous domain of basement membrane collagen. J Biol Chem 263:10481\u201310488","journal-title":"J Biol Chem"},{"key":"CR24","first-page":"656","volume":"48","author":"A Martinez-Hernandez","year":"1983","unstructured":"Martinez-Hernandez A, Amenta PS (1983) The basement membrane in pathology. Lab Invest 48:656\u2013677","journal-title":"Lab Invest"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1038\/ki.1982.72","volume":"21","author":"RC McCoy","year":"1982","unstructured":"McCoy RC, Johnson HK, Stone WJ, Wilson CB (1982) Absence of nephritogenic GBM antigen(s) in some patients with hereditary nephritis. Kidney Int 21:642\u2013652","journal-title":"Kidney Int"},{"key":"CR26","first-page":"35","volume":"57","author":"DS Milliner","year":"1982","unstructured":"Milliner DS, Pierides AM, Holley KE (1982) Renal transplantation in Alport's syndrome. Anti-glomerular basement membrane glomerulonephritis in the allograft. Mayo Clin Proc 57:35\u201343","journal-title":"Mayo Clin Proc"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"6005","DOI":"10.1016\/S0021-9258(18)68738-1","volume":"263","author":"M Moos Jr","year":"1988","unstructured":"Moos M Jr, Nguyen NY, Liu T-Y (1988) Reproducible high yield sequencing of proteins electrophoretically separated and transferred to an inert support. J Biol Chem 263:6005\u20136008","journal-title":"J Biol Chem"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/S0022-3476(80)80746-3","volume":"96","author":"DL Olson","year":"1980","unstructured":"Olson DL, Anand SK, Landing BH, Heuser E, Grushkin CM, Lieberman E (1980) Diagnosis of hereditary nephritis by failure of glomeruli to bind anti-glomerular basement membrane antibodies. J Pediatr 96:697\u2013699","journal-title":"J Pediatr"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"7681","DOI":"10.1016\/S0021-9258(17)39662-X","volume":"260","author":"T Pihlajaniemi","year":"1985","unstructured":"Pihlajaniemi T, Tryggvason K, Myers JC, Kurkinen M, Lebo R, Cheung M-C, Prockop DJ, Boyd CD (1985) cDNA clones coding for the pro-\u03b11(IV) chain of human type IV procollagen reveal and unusual homology of amino acid sequences in two halves of the carboxyl-terminal domain. J Biol Chem 260:7681\u20137687","journal-title":"J Biol Chem"},{"key":"CR30","first-page":"134","volume":"25","author":"S Qu\u00e9rin","year":"1986","unstructured":"Qu\u00e9rin S, No\u00ebl L-H, Gr\u00fcnfeld J-P, Droz D, Mahieu P, Berger J, Kreis H (1986) Linear glomerular IgG fixation in renal allografts: incidence and significance in Alport's syndrome. Clin Nephrol 25:134\u2013140","journal-title":"Clin Nephrol"},{"key":"CR31","doi-asserted-by":"crossref","first-page":"13374","DOI":"10.1016\/S0021-9258(18)37714-7","volume":"263","author":"J Saus","year":"1988","unstructured":"Saus J, Wieslander J, Langeveld JP, Quinones S, Hudson BG (1988) Identification of the Goodpasture antigen as the alpha 3(IV) chain of collagen IV. J Biol Chem 263:13374\u201313380","journal-title":"J Biol Chem"},{"key":"CR32","first-page":"613","volume":"60","author":"COS Savage","year":"1989","unstructured":"Savage COS, Noel L-H, Crutcher E, Price SRG, Grunfeld JP, Lockwood CM (1989) Hereditary nephritis: immunoblotting studies of the glomerular basement membrane. Lab Invest 60:613\u2013618","journal-title":"Lab Invest"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1159\/000185113","volume":"50","author":"B Shah","year":"1988","unstructured":"Shah B, First MR, Mendoza NC, Clyne DH, Alexander JW, Weiss MA (1988) Alport's syndrome: risk of glomerulonephritis induced by anti-glomerular-basement-membrane antibody after renal transplantation. Nephron 50:34\u201338","journal-title":"Nephron"},{"key":"CR34","first-page":"435","volume":"56","author":"P Thorner","year":"1987","unstructured":"Thorner P, Jansen B, Baumal R, Valli VE, Goldberger A (1987) Samoyed hereditary glomerulopathy. Immunohistochemical staining of basement membrane sof kidney for laminin, collagen type IV, fibronectin, and Goodpasture antigen, and correlation with electron microscopy of glomerular capillary basement membranes. Lab Invest 56:435\u2013443","journal-title":"Lab Invest"},{"key":"CR35","first-page":"1047","volume":"134","author":"P Thorner","year":"1989","unstructured":"Thorner P, Baumal R, Binnington A, Valli VEO, Marrano P, Clarke H (1989a) The NC1 domain of collagen type IV in neonatal dog glomerular basement membranes. Significance in Samoyed hereditary glomerulopathy. Am J Pathol 134:1047\u20131054","journal-title":"Am J Pathol"},{"key":"CR36","first-page":"160","volume":"31","author":"PS Thorner","year":"1989","unstructured":"Thorner PS, Baumal R, Eddy A, Marrano P (1989b) Characterization of the NC1 domain of collagen type IV in glomerular basement membranes (GBM) and of antibodies to GBM in a patient with anti-GBM nephritis. Clin Nephrol 31:160\u2013168","journal-title":"Clin Nephrol"},{"key":"CR37","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1038\/ki.1989.62","volume":"35","author":"P Thorner","year":"1989","unstructured":"Thorner P, Baumal R, Valli VEO, Mahuran D, McInnes R, Marrano P (1989c) Abnormalities in the NC1 domain of collagen type IV in GBM in canine hereditary nephritis. Kidney Int 35:843\u2013850","journal-title":"Kidney Int"},{"key":"CR38","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/BF01678979","volume":"416","author":"PS Thorner","year":"1990","unstructured":"Thorner PS, Baumal R, Eddy A, Marrano PM (1990) A study by immunofluorescence microscopy of the NC1 domain of collagen type IV in glomerular basement membranes of two patients with hereditary nephritis. Virchows Arch [A] 416:205\u2013212","journal-title":"Virchows Arch [A]"},{"key":"CR39","doi-asserted-by":"crossref","first-page":"3838","DOI":"10.1073\/pnas.81.12.3838","volume":"81","author":"J Wieslander","year":"1984","unstructured":"Wieslander J, Barr JF, Butkowski RJ, Edwards SJ, Bygren P, Heineg\u00e5rd D, Hudson BG (1984a) Goodpasture antigen of the glomerular basement membrane: localization to noncollagenous regions of type IV collagen. Proc Natl Acad Sci USA 81:3838\u20133842","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR40","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1073\/pnas.81.5.1544","volume":"81","author":"J Wieslander","year":"1984","unstructured":"Wieslander J, Bygren P, Heineg\u00e5rd D (1984b) Isolation of the specific glomerular basement membrane antigen involved in Goodpasture syndrome. Proc Natl Acad Sci USA 81:1544\u20131548","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR41","doi-asserted-by":"crossref","first-page":"8564","DOI":"10.1016\/S0021-9258(17)39510-8","volume":"260","author":"J Wieslander","year":"1985","unstructured":"Wieslander J, Langeveld J, Butkowski R, Jodlowski M, Noelken M, Hudson BG (1985) Physical and immunochemical studies of the globular domain of type IV collagen: cryptic properties of the Goodpasture antigen. J Biol Chem 260:8564\u20138570","journal-title":"J Biol Chem"},{"key":"CR42","doi-asserted-by":"crossref","first-page":"3831","DOI":"10.4049\/jimmunol.134.6.3831","volume":"134","author":"K Yoshioka","year":"1985","unstructured":"Yoshioka K, Kleppel M, Fish AJ (1985a) Analysis of nephritogenic antigens in human glomerular basement membrane by two-dimensional gel electrophoresis. J Immunol 134:3831\u20133837","journal-title":"J Immunol"},{"key":"CR43","first-page":"156","volume":"121","author":"K Yoshioka","year":"1985","unstructured":"Yoshioka K, Michael AF, Velosa J, Fish AJ (1985b) Detection of hidden nephritogenic antigen determinants in human renal and nonrenal basement membranes. Am J Pathol 121:156\u2013165","journal-title":"Am J Pathol"},{"key":"CR44","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/0888-7543(91)90215-Z","volume":"91","author":"J Zhou","year":"1991","unstructured":"Zhou J, Barker DF, Hostikka SL, Gregory MC, Atkin CL, Tryggvason K (1991) Single base mutation in \u03b15(IV) collagen chain gene converting a conserved cysteine to serine in Alport syndrome. Genomics 91:10\u201318","journal-title":"Genomics"}],"container-title":["Virchows Archiv A Pathological Anatomy and Histopathology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01606875.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01606875\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01606875","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T11:36:12Z","timestamp":1706182572000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01606875"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,11]]},"references-count":44,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1992,11]]}},"alternative-id":["BF01606875"],"URL":"https:\/\/doi.org\/10.1007\/bf01606875","relation":{},"ISSN":["0174-7398","1432-2307"],"issn-type":[{"value":"0174-7398","type":"print"},{"value":"1432-2307","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,11]]}}}