{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T13:35:30Z","timestamp":1776692130951,"version":"3.51.2"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1997,3,1]],"date-time":"1997-03-01T00:00:00Z","timestamp":857174400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Osteoporosis Int"],"published-print":{"date-parts":[[1997,3]]},"DOI":"10.1007\/bf01623688","type":"journal-article","created":{"date-parts":[[2005,5,1]],"date-time":"2005-05-01T05:34:10Z","timestamp":1114925650000},"page":"133-137","source":"Crossref","is-referenced-by-count":8,"title":["Intermittent etidronate partially prevents bone loss in hirsute hyperandrogenic women treated with GnRH agonist"],"prefix":"10.1007","volume":"7","author":[{"given":"N.","family":"Zamberlan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Castello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Gatti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Rossini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Braga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Fracassi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Adami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1210\/jcem-61-5-905","volume":"61","author":"CC Johnston Jr","year":"1985","unstructured":"Johnston CC Jr, Hui SL, Witt RM, Appledorn R, Baker RS, Longcope C. Early menopausal changes in bone mass and sex steroids. J Clin Endocrinol Metab 1985;61:905\u201311.","journal-title":"J Clin Endocrinol Metab"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1210\/jcem-55-6-1124","volume":"55","author":"C Christiansen","year":"1982","unstructured":"Christiansen C, Christensen MS, Larsen NE, Transbol I. Pathophysiological mechanism of estrogen effect on bone metabolism: dose-response relationship in early postmenopausal women. J Clin Endocrinol Metab 1982;55:1124\u201330.","journal-title":"J Clin Endocrinol Metab"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1056\/NEJM198411153112002","volume":"311","author":"LS Richelson","year":"1984","unstructured":"Richelson LS Wahner HW, Melton LJ III, Riggs BL. Relative contributions of aging and estrogen deficiency to postmenopausal bone loss. N Engl J Med 1984;311:1273\u20135.","journal-title":"N Engl J Med"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1210\/jcem-70-4-1055","volume":"70","author":"Sh Scharla","year":"1990","unstructured":"Scharla Sh, Minne HW, Waibel-Treber S, Schaible A, Lempert UG, Wuster C, et al. Bone mass reduction after estrogen deprivation by long-acting gonadotropin-releasing hormone agonists and its relation to pretreatment serum concentrations of 1,25-dihydroxyvitamin D3. J Clin Endocrinol Metab 1990;70:1055\u201361.","journal-title":"J Clin Endocrinol Metab"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1210\/jcem-67-4-701","volume":"67","author":"JS Johansen","year":"1988","unstructured":"Johansen JS, Riis BJ, Hassager C, Moen M, Jacobson J, Christiansen C. The effect of a gonadotropin-releasing hormone agonist analog (nafarelin) on bone metabolism. J Clin Endocrinol Metab 1988;67:701\u20136.","journal-title":"J Clin Endocrinol Metab"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1210\/jcem-65-1-159","volume":"65","author":"JA Gudmundsson","year":"1987","unstructured":"Gudmundsson JA, Ljunghall S, Bergquist C, Wide L, Nillius SJ. Increased bone turnover during gonadotrophin-releasing hormone superagonist-induced ovulation inhibition. J Clin Endocrinol Metab 1987;65:159\u201363.","journal-title":"J Clin Endocrinol Metab"},{"key":"CR7","first-page":"3406","volume":"80","author":"R Azziz","year":"1995","unstructured":"Azziz R, Ochoa TM, Bradley ELJ, Potter HD, Boots LR. Leuprolide and estrogen versus oral contraceptive pills for the treatment of hirsutism: a prospective randomized study. J Clin Endocrinol Metab 1995;80:3406\u201311.","journal-title":"J Clin Endocrinol Metab"},{"key":"CR8","first-page":"3412","volume":"80","author":"JS Heiner","year":"1995","unstructured":"Heiner JS, Greendale GA, Kawakami AK, Lapolt PS, Fisher M, Young D, Judd HL. Comparison of a gonadotropin-releasing hormone agonist and a low dose oral contraceptive given alone or together in the treatment of hirsutism. J Clin Endocrinol Metab 1995;80:3412\u20138.","journal-title":"J Clin Endocrinol Metab"},{"key":"CR9","first-page":"3403","volume":"80","author":"RS Rittmaster","year":"1995","unstructured":"Rittmaster RS. Gonadotropin-releasing hormone (GnRH) agonist and estrogen-progestin replacement for the treatment of hirsutism: evaluating the results. J Clin Endocrinol Metab 1995;80:3403\u20135.","journal-title":"J Clin Endocrinol Metab"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/S0015-0282(16)54837-7","volume":"57","author":"C Carlo Di","year":"1992","unstructured":"Di Carlo C, Shoham Z, MacDougall J, Patel A, Hall ML, Jacobs HS. Polycystic ovaries as a relative protective factor for bone mineral loss in young women with amenorrhea. Fertil Steril 1992;57:314\u20139.","journal-title":"Fertil Steril"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1365-2265.1989.tb02235.x","volume":"30","author":"JE Dixon","year":"1989","unstructured":"Dixon JE, Rodin A, Murby B, Chapman MG, Fogelman I. Bone mass in hirsute women with androgen excess. Clin Endocrinol 1989;30:271\u20137.","journal-title":"Clin Endocrinol"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1210\/jcem-70-4-920","volume":"70","author":"BJ Riis","year":"1990","unstructured":"Riis BJ, Christiansen C, Johansen JS, Jacobson J. Is it possible to prevent bone loss in young women treated with luteinizing hormone-releasing hormone agonists? J Clin Endocrinol Metab 1990;70:920\u20134.","journal-title":"J Clin Endocrinol Metab"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1365-2265.1988.tb00248.x","volume":"29","author":"WH Matta","year":"1988","unstructured":"Matta WH, Shaw RW, Hesp R, Evans R. Reversible trabecular bone density loss following induced hypo-estrogenism with the GnRH analogue buserelin in premenopausal women. Clin Endocrinol 1988;29:45\u201351.","journal-title":"Clin Endocrinol"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/8756-3282(94)00038-2","volume":"16","author":"JE Compston","year":"1995","unstructured":"Compston JE, Yamaguchi K, Croucher PI, Garrahan NJ, Lindsay PC, Shaw RW. The effects of gonadotropin-releasing hormone agonists on iliac crest cancellous bone structure in women with endometriosis. Bone 1995;16:261\u20137.","journal-title":"Bone"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/BF02106098","volume":"5","author":"C Roux","year":"1995","unstructured":"Roux C, Pelissier C, Listrat V, Kolta S, Simonetta C, Guignard M, Dougados M, Amor B. Bone loss during gonadotropin releasing hormone agonist treatment and use of nasal calcitonin. Osteoporos Int 1995;5:185\u201390.","journal-title":"Osteoporos Int"},{"key":"CR16","first-page":"36","volume":"99","author":"SJ Wimalawansa","year":"1995","unstructured":"Wimalawansa SJ. Combined therapy with estrogen and etidronate has an additive effect on bone mineral density in the hip and vertebrae: four-year randomized study. Ann Intern Med 1995;99:36\u201342.","journal-title":"Ann Intern Med"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/0002-9343(93)90350-X","volume":"95","author":"ST Harris","year":"1993","unstructured":"Harris ST, Watts NB, Jackson RD, Genant HK, Wasnich RD, Ross P, et al. Four year study of intermittent cyclic etidronate treatment of postmenopausal osteoporosis: three years of blinded therapy followed by one year of open therapy. Am J Med 1993;95:552\u201366.","journal-title":"Am J Med"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1210\/er.16.3.322","volume":"16","author":"DA Ehrmann","year":"1995","unstructured":"Ehrmann DA, Barnes RB, Rosenfield RL. Polycystic ovary syndrome as a form of functional ovarian hyperandrogenism due to dysregulation of androgen secretion. Endocr Rev 1995;16:322\u201353.","journal-title":"Endocr Rev"},{"key":"CR19","first-page":"397","volume":"15","author":"G Mazzi","year":"1990","unstructured":"Mazzi G, Fioravanzo S, Scapini P. Acid hydrolysis internal standard chromatography by an ion exchange column instead of the classical apolar P-18 column. Giom It Chim Clin 1990;15:397\u2013404.","journal-title":"Giom It Chim Clin"},{"key":"CR20","first-page":"345","volume-title":"The current status of endometriosis: research and management","author":"JP Devogelaer","year":"1993","unstructured":"Devogelaer JP, Nagant de Deuxchaisnes C, Donnez J. Action of the luteinizing hormone releasing hormone agonists on bone mineral density. In: Brosens I, Donnez J, editors. The current status of endometriosis: research and management. Proceedings of the 3rd world congress on endometriosis, Brussels, June 1992. New York: Parthenon Publishing, 1993:345\u201368."},{"key":"CR21","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1210\/jcem-69-4-837","volume":"69","author":"F Comite","year":"1989","unstructured":"Comite F, Delman M, Hutchinson-Williams K, DeCherney AH, Jensen P. Reducedbone mass in reproductive-aged women with endometriosis. J Clin Endocrinol Metab 1989;69:837\u201342.","journal-title":"J Clin Endocrinol Metab"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1002\/jbmr.5650091003","volume":"9","author":"RP Heaney","year":"1949","unstructured":"Heaney RP. The bone-remodeling transient: implications for the interpretation of clinical studies of bone mass change. J Bone Miner Res 1949;9:1515\u201323.","journal-title":"J Bone Miner Res"},{"key":"CR23","first-page":"104","volume":"81","author":"AT Leather","year":"1993","unstructured":"Leather AT, Studd JWW, Watson NR, Holland EFN. The prevention of bone loss in young women treated with GnRH analogues with \u201cadd-back\u201d estrogen therapy. Obstet Gynecol 1993;81:104\u20137.","journal-title":"Obstet Gynecol"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1056\/NEJM199412153312404","volume":"331","author":"JS Finkelstein","year":"1994","unstructured":"Finkelstein JS, Klibanski A, Schaefer EH, Hornstein MD, Schiff I, Neer R. Parathyroid hormone for the prevention of bone loss induced by estrogen deficiency. N Engl J Med 1994;331:1618\u201323.","journal-title":"N Engl J Med"}],"container-title":["Osteoporosis International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01623688.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01623688\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01623688","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,7]],"date-time":"2019-05-07T20:25:27Z","timestamp":1557260727000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01623688"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,3]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1997,3]]}},"alternative-id":["BF01623688"],"URL":"https:\/\/doi.org\/10.1007\/bf01623688","relation":{},"ISSN":["0937-941X","1433-2965"],"issn-type":[{"value":"0937-941X","type":"print"},{"value":"1433-2965","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,3]]}}}