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After healing, maintenance treatment is useful in preventing ulcer recurrence, but once the drug is stopped, recurrence soon follows. At present the evidence suggests that treatment with cimetidine may have to be life\u2010long. Most surgeons would not accept this as an alternative to surgery in the treatment of chronic duodenal ulcer. However, in the treatment of recurrent ulceration after surgery, and where symptoms are relieved by cimetidine, the patient may prefer drugs to further operation.<\/jats:p>","DOI":"10.1007\/bf01654808","type":"journal-article","created":{"date-parts":[[2005,5,9]],"date-time":"2005-05-09T09:17:33Z","timestamp":1115630253000},"page":"745-750","source":"Crossref","is-referenced-by-count":5,"title":["Cimetidine and the gastric surgeon"],"prefix":"10.1002","volume":"3","author":[{"given":"Charles G.","family":"Clark","sequence":"first","affiliation":[{"name":"Surgical Unit University College Hospital Medical School WC1E 6JJ London England"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul B.","family":"Boulos","sequence":"additional","affiliation":[{"name":"Surgical Unit University College Hospital Medical School WC1E 6JJ London England"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1979,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01654717"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(78)90771-0"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6120.1095"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6130.123-a"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(72)92719-5"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/00325481.1978.11714808"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(77)92954-3"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6134.433"},{"key":"e_1_2_1_10_1","first-page":"163","volume-title":"Cimetidine; Proceedings of the 2nd International Symposium on H2\u2010Receptor Antagonists","author":"Spence R.W.","year":"1976"},{"key":"e_1_2_1_11_1","first-page":"124","volume-title":"Cimetidine; Proceedings of the 2nd International Symposium on H2\u2010Receptor Antagonists","author":"Blackwood W.S.","year":"1976"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(78)91200-X"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6134.433"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6134.433-a"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800650302"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01563693"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1954.01270020006002"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(76)80415-5"},{"key":"e_1_2_1_19_1","first-page":"150","article-title":"Cimetidine and postgastrectomy recurrent ulcer","volume":"9","author":"Delle Fave G.F.","year":"1977","journal-title":"Rend. 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