{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T12:56:07Z","timestamp":1761742567392},"reference-count":58,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[1984,10,1]],"date-time":"1984-10-01T00:00:00Z","timestamp":465436800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1984,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Patients with mansonic schistosomiasis and portal hypertension are usually young, with good liver functional reserve, huge splenomegaly, and hypersplenism detectable only by alterations seen in laboratory tests. Patients who are not operated on do not develop portosystemic encephalopathy (PSE). Angiographic alterations are characteristic and totally different from those observed in patients with liver atrophy or cirrhosis. Digestive tract hemorrhage is the most severe complication. The patient with schistosomiasis is, therefore, a good model for the study of the consequences caused by the surgical treatment of portal hypertension. The evaluation, however, of results published in the literature regarding schistosomiasis is practically impossible. In a review of 130 publications referring to 4,516 surgically treated patients, the absence of prospective or retrospective studies with adequate controls was observed, and only 3.2% of the patients were followed for 5 years. According to available data, a total of 29 different surgical techniques has been employed, 81.6% of which are represented by simple splenectomy, esophagogastric devascularization (EGDS), and splenorenal shunt (SRS). Splenectomy was the surgical procedure showing the highest rate of recurrent hemorrhage (54.3%), and the portocaval shunt had the highest PSE incidence (60%). Portosystemic encephalopathy incidence after SRS was 29%. Thus, in view of a lack of objective information, in 1977 our group started a prospective, randomized study comparing the results of the surgical procedures most widely used in our country: selective portal decompression (SPD), EGDS, and SRS. The randomization was interrupted after 94 patients had been operated on (32 SRS, 30 SPD, and 32 EGDS) because of a highly significant PSE incidence in the SRS group. Preliminary results as of January, 1984, refer to an average follow\u2010up period of 53\u00a0months (minimum 29, maximum 77\u00a0months). In the SRS group, the late mortality rate was 18.7%, and the incidence of PSE was 31.2%. Among the patients included in this group, 18.7% had arterial hypertension. In the SPD group, late mortality occurred in 10% of the cases, and PSE in 13.3%, while a mild hyperbilirubinemia was seen in 43.3% of patients. Recurrent hemorrhage and ascites had an approximately similar incidence in the 3\u00a0groups.<\/jats:p>","DOI":"10.1007\/bf01655771","type":"journal-article","created":{"date-parts":[[2005,5,8]],"date-time":"2005-05-08T06:27:32Z","timestamp":1115533652000},"page":"738-752","source":"Crossref","is-referenced-by-count":35,"title":["Surgical treatment of portal hypertension in schistosomiasis"],"prefix":"10.1002","volume":"8","author":[{"given":"Silvano","family":"Raia","sequence":"first","affiliation":[{"name":"Department of Surgery Liver Unit Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Mies","sequence":"additional","affiliation":[{"name":"Department of Surgery Liver Unit Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Luiz","family":"Macedo","sequence":"additional","affiliation":[{"name":"Department of Surgery Liver Unit Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1984,10]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"1267","volume-title":"Liver and Biliary Disease","author":"Ong G.B.","year":"1979"},{"key":"e_1_2_1_3_1","first-page":"884","volume-title":"Doen\u00e7as infecciosas e parasit\u00e1rias","author":"Prata A.","year":"1982"},{"key":"e_1_2_1_4_1","first-page":"185","article-title":"Fatores relacionados com o desenvolvimento das formas cl\u00ednicas da esquistossomose mans\u00f4nica","volume":"25","author":"Coutinho A.","year":"1979","journal-title":"Rev. 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