{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T07:27:42Z","timestamp":1761290862124},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[1984,12,1]],"date-time":"1984-12-01T00:00:00Z","timestamp":470707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1984,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>The collective term \u201cpancreatic cancer\u201d should be replaced by more specific terminology indicating the histological subtype, e.g., pancreatic ductal adenocarcinoma, ampullary adenocarcinoma, duodenal carcinoma, pancreatic cystadenocarcinoma, cholangiocarcinoma, and malignant islet cell carcinoma. Each of these tumors has its own inherent prognostic and therapeutic characteristics\u201095% of ampullary lesions being resectable in contrast to \u00b110% of pancreatic ductal malignancies and comparable 5\u2010year survival figures for these two subtypes are 40% and 5%, respectively<\/jats:bold>.<\/jats:p><jats:p><jats:bold>Since the results of adjuvant therapy (chemo\u2010 and\/or radiotherapy) have been dismal, the only chance of cure remains resective therapy, either by the performance of a total or subtotal pancreatectomy (Whipple procedure). The operative mortality rate for these procedures at our institution has been 12% and 4%, respectively, with corresponding 5\u2010year survival rates of 2% and 4%. Despite earlier promise that total pancreatectomy only would be a superior procedure (elimination of the pancreatojejunal anastomosis, wider lymphadenectomy, irradication of multicentric disease), the operation has thus far not fulfilled these expectations<\/jats:bold>.<\/jats:p><jats:p><jats:bold>The Whipple procedure remains the resective procedure of choice at our institution\u2014total pancreatectomy being performed principally in those patients in whom a safe pancreatojejunal anastomosis cannot be constructed<\/jats:bold>.<\/jats:p><jats:p><jats:bold>Value of early diagnosis in patients with ductal adenocarcinoma does not appear to imply improved prognosis. Energies should be diverted toward etiological identification of this lethal malignancy which is steadily increasing in incidence<\/jats:bold>.<\/jats:p>","DOI":"10.1007\/bf01656028","type":"journal-article","created":{"date-parts":[[2005,5,8]],"date-time":"2005-05-08T02:23:31Z","timestamp":1115519011000},"page":"880-888","source":"Crossref","is-referenced-by-count":99,"title":["Pancreatic resection for carcinoma of the pancreas: Whipple versus total pancreatectomy\u2014An institutional perspective"],"prefix":"10.1002","volume":"8","author":[{"given":"Jon A.","family":"van Heerden","sequence":"first","affiliation":[{"name":"Department of Surgery Mayo Clinic 55905 Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1984,12]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(81)90163-X"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1977.01370040103016"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(67)90256-5"},{"key":"e_1_2_1_5_1","first-page":"959","article-title":"Preservation of the pylorus in pancreaticoduodenectomy","volume":"146","author":"Traverso L.W.","year":"1978","journal-title":"Surg. 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Proc."},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1983.03340110047033"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197811)42:5<2494::AID-CNCR2820420554>3.0.CO;2-R"},{"key":"e_1_2_1_17_1","first-page":"371","volume":"71","author":"McPherson G.A.D.","year":"1984","journal-title":"Preoperative percutaneous transhepatic biliary damage: The results of a controlled trial"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01656028.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01656028\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/BF01656028","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T17:27:32Z","timestamp":1703698052000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/BF01656028"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,12]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1984,12]]}},"alternative-id":["10.1007\/BF01656028"],"URL":"https:\/\/doi.org\/10.1007\/bf01656028","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,12]]}}}