{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T01:30:21Z","timestamp":1759541421987},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1982,1,1]],"date-time":"1982-01-01T00:00:00Z","timestamp":378691200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008392","name":"Sundhed og Sygdom, Det Frie Forskningsr\u00e5d","doi-asserted-by":"publisher","award":["SLF 512\u20135456"],"award-info":[{"award-number":["SLF 512\u20135456"]}],"id":[{"id":"10.13039\/100008392","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1982,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In a prospective, randomized study, 691 patients with duodenal (DU), pyloric (PU), or prepyloric (PPU) ulcers have been followed for 2\u20135 years after operation with parietal cell vagotomy (PCV) or selective gastric vagotomy with drainage (SGV+D). About half the patients have been followed for 5 years. Cumulative 5\u2010year recurrence rates, calculated by a life table method, suggest a higher recurrence rate for patients with DU when operated with PCV (15%) than when operated with SGV + D (9%), but the difference was not statistically significant (<jats:italic>p<\/jats:italic>&gt;0.05). Patients with PU\/PPU had higher recurrence rates following either procedure than patients with DU (PCV: 33%; SGV+D: 14%).<\/jats:p><jats:p>A study of the change in recurrence risk as a function of time after operation suggests that the recurrence rate following SGV+D when used for DU will continue to rise after 5 years, but probably very slowly. The recurrence rate after 5 years is unpredictable, however, for PCV when used for DU, and unpredictable for both methods when used for PU\/PPU.<\/jats:p><jats:p>The recurrence rate was found to be independent of the level of preoperative gastric acid secretion, and this was true for both PCV and SGV+D, An increased recurrence rate was, on the other hand, found to be associated with &lt;50% postoperative reduction in pentagastrin\u2010stimulated acid secretion.<\/jats:p>","DOI":"10.1007\/bf01656378","type":"journal-article","created":{"date-parts":[[2005,5,8]],"date-time":"2005-05-08T01:50:10Z","timestamp":1115517010000},"page":"86-92","source":"Crossref","is-referenced-by-count":62,"title":["The Aarhus County Vagotomy Trial: Trends in the problem of recurrent ulcer after parietal cell vagotomy and selective gastric vagotomy with drainage"],"prefix":"10.1002","volume":"6","author":[{"given":"Daniel","family":"Andersen","sequence":"first","affiliation":[{"name":"Departments of Surgical Gastroenterology Kommunehospitalet and Amtssygehuset Aarhus"},{"name":"Department of Surgery, Centralsygehuset, Randers University of Aarhus Denmark"},{"name":"Department K of Surgical Gastroenterology Odense University Hospital DK\u20105000 Odense C Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik","family":"Amdrup","sequence":"additional","affiliation":[{"name":"Departments of Surgical Gastroenterology Kommunehospitalet and Amtssygehuset Aarhus"},{"name":"Department of Surgery, Centralsygehuset, Randers University of Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans","family":"H\u00d8strup","sequence":"additional","affiliation":[{"name":"Departments of Surgical Gastroenterology Kommunehospitalet and Amtssygehuset Aarhus"},{"name":"Department of Surgery, Centralsygehuset, Randers University of Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Finn Hanberg","family":"S\u00d8rensen","sequence":"additional","affiliation":[{"name":"Departments of Surgical Gastroenterology Kommunehospitalet and Amtssygehuset Aarhus"},{"name":"Department of Surgery, Centralsygehuset, Randers University of Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1982,1]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01574469"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01574470"},{"key":"e_1_2_1_4_1","first-page":"223","volume-title":"Gastrins and the Vagus","author":"Andersen D.","year":"1979"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1958.10501452"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/00401706.1972.10488991"},{"key":"e_1_2_1_7_1","first-page":"15","article-title":"Nonparametric inference in connection with multiple decrement models","volume":"3","author":"Aalen O.","year":"1976","journal-title":"Scand. 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