{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T00:17:31Z","timestamp":1705018651694},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[1987,6,1]],"date-time":"1987-06-01T00:00:00Z","timestamp":549504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1987,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>In a prospective multicenter trial, 560 patients with peptic ulcer were treated with proximal gastric vagotomy (PGV) without drainage. Four hundred ninety\u2010three patients had duodenal ulcer (DU), 35 pyloric (PU), and 32 prepyloric ulceration (PPU). Actuarial 5\u2010year recurrence rates were 14%, 35%, and 33%, respectively, and were significantly higher in PU and PPU than in DU. In a separate study, thickness of the pyloric and antral wall was assessed in the resection specimens of patients with similarly defined ulcer types and in controls. There was significant thickening of the muscular layer of the pylorus and antrum in patients with PU and PPU compared to those with DU and controls. It appears that this muscular hypertrophy and fibrosis could be one factor responsible for the failure of PGV without drainage in PU and PPU. Preliminary results indicate a possible beneficial effect of adding a drainage procedure to PGV when treating pyloric channel ulcers. Our results emphasize that pyloric channel ulcers must be considered as a particular entity of peptic ulcer disease and should no longer be assigned to the duodenal ulcer group<\/jats:bold>.<\/jats:p>","DOI":"10.1007\/bf01658112","type":"journal-article","created":{"date-parts":[[2005,5,8]],"date-time":"2005-05-08T09:13:50Z","timestamp":1115543630000},"page":"339-344","source":"Crossref","is-referenced-by-count":9,"title":["Pyloric and prepyloric ulcers"],"prefix":"10.1002","volume":"11","author":[{"given":"Claude","family":"Muller","sequence":"first","affiliation":[{"name":"Department of Surgery University of Basel Kantonsspital CH\u20104031 Basel Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doris","family":"Liebermann\u2010Meffert","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Basel Kantonsspital CH\u20104031 Basel Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Allg\u00f6wer","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Basel Kantonsspital CH\u20104031 Basel Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1987,6]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-196512000-00005"},{"key":"e_1_2_1_3_1","first-page":"323","article-title":"Recurrent ulcer after proximal gastric vagotomy","volume":"493","author":"Palmu A.","year":"1981","journal-title":"Acta Chir. 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Acid secretory patterns in patients with prepyloric, pyloric and duodenal ulcer","volume":"26","author":"\u00f8rnsholt J.","year":"1983","journal-title":"Digestion"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000399582"},{"key":"e_1_2_1_12_1","first-page":"9","article-title":"Elektive chirurgische Eingriffe in der Ulcus duodeni\u2010Therapie","volume":"53","author":"Muller C.","year":"1982","journal-title":"Chirurg"},{"key":"e_1_2_1_13_1","first-page":"128","article-title":"Klinische Studien: Berechnen und Vergleichen von Ueberlebenskurven","volume":"111","author":"Berchtold W.","year":"1981","journal-title":"Schweiz. Med. 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