{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T21:42:09Z","timestamp":1773178929916,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[1989,3,1]],"date-time":"1989-03-01T00:00:00Z","timestamp":604713600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1989,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Endoscopic laser treatment was initially applied for gastrointestinal bleeding, but has been actively extended, especially in Japan, to the curative treatment of early upper gastrointestinal cancers.<\/jats:p><jats:p>We have treated 10 cases of early gastric cancer and 1 case of early esophageal cancer by Nd\u2010YAG laser radiation, and 2 cases of early gastric cancer by photochemical therapy (PCT) with argon laser + hematoporphyrin derivative. Also, 62 cases of advanced cancer were treated, 10 of the esophagus and 52 of the stomach, for bleeding (18 cases) or stenosis (34 cases). The cases were nonresectable or they were patients who refused surgery. Satisfactory results were obtained by treatment with YAG laser, but have not yet been obtained with PCT.<\/jats:p><jats:p>In order to find indications for the possible extension of endoscopic laser therapy to operable cases of early gastric cancer, we studied lymph node metastases in 200 cases of early gastric cancer surgically treated by us. It was found that early gastric cancers (both mucosal and submucosal) measuring less than 2\u00a0cm in diameter, of type I, IIa, and IIc (without ulcer scar), had no lymph node metastases and such cases can be treated by local therapy\u2014such as endoscopic laser therapy.<\/jats:p><jats:p>In palliative endoscopic laser therapy for complications of advanced gastrointestinal cancers, there are no major problems with active performance. We obtained a high (90%) hemostatic rate in bleeding cases of upper gastrointestinal cancer and a satisfactory (65%) rate of dilating effect in cases of cancerous stenosis at the esophagus and cardia. A national survey in this field is also discussed in this report to show the present status of endoscopic laser therapy in the curative and palliative treatment of upper gastrointestinal cancer in Japan.<\/jats:p>","DOI":"10.1007\/bf01658393","type":"journal-article","created":{"date-parts":[[2005,5,9]],"date-time":"2005-05-09T05:41:26Z","timestamp":1115617286000},"page":"158-164","source":"Crossref","is-referenced-by-count":47,"title":["Endoscopic laser therapy in the curative and palliative treatment of upper gastrointestinal cancer"],"prefix":"10.1002","volume":"13","author":[{"given":"Hiroaki","family":"Suzuki","sequence":"first","affiliation":[{"name":"Department of Surgery Aoto Hospital Jikei University School of Medicine 6\u201041\u20102, Aoto, Katsushika 125 Tokyo Japan"},{"name":"Department of Endoscopy and Second Department of Surgery Jikei University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Otomi","family":"Miho","sequence":"additional","affiliation":[{"name":"Department of Surgery Aoto Hospital Jikei University School of Medicine 6\u201041\u20102, Aoto, Katsushika 125 Tokyo Japan"},{"name":"Department of Endoscopy and Second Department of Surgery Jikei University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Surgery Aoto Hospital Jikei University School of Medicine 6\u201041\u20102, Aoto, Katsushika 125 Tokyo Japan"},{"name":"Department of Endoscopy and Second Department of Surgery Jikei University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayuki","family":"Kohyama","sequence":"additional","affiliation":[{"name":"Department of Surgery Aoto Hospital Jikei University School of Medicine 6\u201041\u20102, Aoto, Katsushika 125 Tokyo Japan"},{"name":"Department of Endoscopy and Second Department of Surgery Jikei University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fusahiro","family":"Nagao","sequence":"additional","affiliation":[{"name":"Department of Surgery Aoto Hospital Jikei University School of Medicine 6\u201041\u20102, Aoto, Katsushika 125 Tokyo Japan"},{"name":"Department of Endoscopy and Second Department of Surgery Jikei University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1989,3]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"316","article-title":"Endoscopic laser therapy for upper gastrointestinal bleeding, experiences in chirurgische Universit\u00e4t Klinik, Marburg, West Germany","volume":"22","author":"Suzuki H.","year":"1980","journal-title":"Gastroenterol. Endosc."},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1018406"},{"key":"e_1_2_1_4_1","first-page":"94","article-title":"Present status of laser endoscopic treatment for cancers of the gastrointestinal tract in Japan","volume":"29","author":"Oguro Y.","year":"1986","journal-title":"Prog. Dig. Endosc."},{"key":"e_1_2_1_5_1","first-page":"98","article-title":"Laser photo\u2010chemical therapy of cancer","volume":"14","author":"Kato D.","year":"1984","journal-title":"Science"},{"key":"e_1_2_1_6_1","first-page":"1511","article-title":"Diagnosis of depth and extension of gastric cancer by chromoscopy and endoscopic ultrasonography","volume":"39","author":"Ida K.","year":"1984","journal-title":"Clin. Surg."},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(85)72260-2"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1018401"},{"key":"e_1_2_1_9_1","unstructured":"Suzuki H. Kawamura M. Sakaeda T. Kohyama M. Nagata T. Miho O. Watanabe Y. Nagao F.:Endoscopic laser therapy for patients with upper gastrointestinal bleeding. In Laser Tokyo '81 K. Atsumi N. Nimsakul editors Inter Group Corp. 1981 pp.511\u2013513."},{"key":"e_1_2_1_10_1","first-page":"1555","article-title":"Recent topics in gastric cancer. Endoscopic laser therapy of gastric cancer","volume":"39","author":"Suzuki H.","year":"1984","journal-title":"Clin. Surg."},{"key":"e_1_2_1_11_1","first-page":"127","volume-title":"Endoscopic Surgery","author":"Hiki Y.","year":"1984"},{"key":"e_1_2_1_12_1","first-page":"739","article-title":"Cause of death after surgery for early gastric cancer","volume":"19","author":"Kaibara N.","year":"1984","journal-title":"Stomach Intestine"},{"key":"e_1_2_1_13_1","first-page":"773","article-title":"Recurrence and mortality in early gastric carcinoma","volume":"19","author":"Takagi K.","year":"1984","journal-title":"Stomach Intestine"},{"key":"e_1_2_1_14_1","first-page":"297","article-title":"Problem of follow up study in early gastric cancer","volume":"30","author":"Nishi M.","year":"1981","journal-title":"Sogo Rinsho"},{"key":"e_1_2_1_15_1","first-page":"489","article-title":"Endoscopic treatment with Nd\u2010YAG laser in gastrointestinal tract","volume":"37","author":"Watanabe Y.","year":"1982","journal-title":"Clin. Surg."},{"key":"e_1_2_1_16_1","first-page":"969","article-title":"Lymph node preserving surgery for early gastric cancer, indication of local resection","volume":"18","author":"Kitaoka K.","year":"1983","journal-title":"J. Jpn. Soc. Cancer Ther."},{"key":"e_1_2_1_17_1","first-page":"23","volume-title":"Endoscopic Surgery","author":"Suzuki H.","year":"1984"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1018404"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01658393.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01658393\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/BF01658393","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T15:10:09Z","timestamp":1704985809000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/BF01658393"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,3]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1989,3]]}},"alternative-id":["10.1007\/BF01658393"],"URL":"https:\/\/doi.org\/10.1007\/bf01658393","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,3]]}}}