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Artificial colloids are free from the risk of transmitting diseases and easy to provide at low costs. The intravascular volume effect of colloid solutions based on dextran, gelatin, or hydroxyethyl starch depends on the physicochemical characteristics of the polymer solution. For the given colloid, the half\u2010life varies from 2 to 8 hours. In addition to the volume effect, dextran provides specific antithrombotic properties. None of the colloids are free from the risk of untoward effects, such as anaphylactoid\/anaphylactic reactions. The low frequency of these reactions and the possibility to prevent and to treat them justifies the use of artificial colloids on a routine basis for shock treatment, volume support, and perioperative hemodilution.<\/jats:p>","DOI":"10.1007\/bf01658463","type":"journal-article","created":{"date-parts":[[2005,5,9]],"date-time":"2005-05-09T05:38:09Z","timestamp":1115617089000},"page":"69-74","source":"Crossref","is-referenced-by-count":34,"title":["The use of plasma substitutes with special attention to their side effects"],"prefix":"10.1002","volume":"11","author":[{"given":"K. F. 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