{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T13:31:49Z","timestamp":1756992709525},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1991,1,1]],"date-time":"1991-01-01T00:00:00Z","timestamp":662688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1991,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Complicated pneumothorax is defined as a recurrent or persistent air leak in the pleural interspace beyond 5\u00a0days despite adequate tube drainage. Up to now, this disorder could only be corrected by open thoracotomy. Endoscopic fibrin pleurodesis is shown to be a method that could obviate, in most cases, the need for thoracotomy. In the last 6 years, 138 of 153 patients presenting with complicated spontaneous pneumothorax were treated with this method. The fibrin sealant consists of 2 components: fibrinogen, factor XIII, and albumin dissolved in aprotinin (3,000\u00a0KIU\/ ml), and a thrombin calcium chloride solution, which is applied through the working channel of a thoracoscope and vaporized with nitrous oxide. In this observation period, 6 (4.4%) recurrences were observed, which were subsequently treated with thoracotomy; a second attempt at fibrin pleurodesis was not undertaken. In all cases, endoscopic sealing was followed by prompt reexpansion of the collapsed lung. Long\u2010term follow\u2010up was satisfactory, pulmonary function tests showed no signs of restrictive dysfunction, and pleural fibrosis was not observed on x\u2010ray as reported in other modes of treatment. Following these results, it is concluded that this method is useful in cases of persistent, therapy\u2010resistant, complicated spontaneous pneumothorax; its effects are durable and it has a low rate of recurrence. It produces a physiological healing process without damage to the pleura<\/jats:bold>.<\/jats:p>","DOI":"10.1007\/bf01658990","type":"journal-article","created":{"date-parts":[[2005,5,8]],"date-time":"2005-05-08T18:16:37Z","timestamp":1115576197000},"page":"146-149","source":"Crossref","is-referenced-by-count":15,"title":["Complicated pneumothorax: Short\u2010 and long\u2010term results of endoscopic fibrin pleurodesis"],"prefix":"10.1002","volume":"15","author":[{"given":"Herwig","family":"Hauck","sequence":"first","affiliation":[{"name":"First Surgical Department Municipal Hospital of Vienna\u2010Lainz Wolkersbergenstrasse 1 1130 Vienna Austria"},{"name":"Department of Thoracic Surgery Pulmonary Centre of the City of Vienna Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe G.","family":"Bull","sequence":"additional","affiliation":[{"name":"First Surgical Department Municipal Hospital of Vienna\u2010Lainz Wolkersbergenstrasse 1 1130 Vienna Austria"},{"name":"Department of Thoracic Surgery Pulmonary Centre of the City of Vienna Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nestor","family":"Pridun","sequence":"additional","affiliation":[{"name":"First Surgical Department Municipal Hospital of Vienna\u2010Lainz Wolkersbergenstrasse 1 1130 Vienna Austria"},{"name":"Department of Thoracic Surgery Pulmonary Centre of the City of Vienna Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1991,1]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.54.3.230"},{"key":"e_1_2_1_3_1","first-page":"983","article-title":"Die Behandlung des Spontanpneumothorax unter Beruecksich\u2010tigung der Rezidivhaeufigkeit","volume":"37","author":"Elert O.","year":"1983","journal-title":"Prax Klin Pneumol."},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.57.1.65"},{"key":"e_1_2_1_5_1","first-page":"235","article-title":"Fibrinklebung, eine neue Behandlungsmethode beim persistierenden und rezidivierenden Spontanpneumothorax","volume":"49","author":"Scheele J.","year":"1978","journal-title":"Chirurg"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.28.6.788"},{"key":"e_1_2_1_7_1","first-page":"291","article-title":"Talc pleurodesis: A controversial issue","volume":"37","author":"Weissberg D.","year":"1981","journal-title":"Poumon Coeur"},{"key":"e_1_2_1_8_1","first-page":"27","volume-title":"Fibrin Sealant in Operative Medicine, Thoracic Surgery\u2010Cardiovascular Surgery, vol. 5","author":"Redl H.","year":"1986"},{"key":"e_1_2_1_9_1","unstructured":"Pridun N. Heindl W.:Die endoskopische Fibrinpleurodese beim komplizierten Pneumothorax. Z. Herz Thorax Gef Suppl. 1 1987."},{"key":"e_1_2_1_10_1","unstructured":"Peacock E.E.:Inflammation and the cellular response to injury. In Wound Repair 3rd edition Philadelphia W.B. Saunders pp.1\u201314."},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1960.tb42862.x"},{"key":"e_1_2_1_12_1","first-page":"295","article-title":"Histologie nach Fibrinklebung","volume":"3","author":"Dinges H.P.","year":"1979","journal-title":"Dtsch. Zschr. Mund\u2010Kiefer\u2010Gesichts\u2010Chir"},{"key":"e_1_2_1_13_1","doi-asserted-by":"crossref","unstructured":"Sp\u00e4ngler H.P. Holle J. Braun F.:Prinzip der Fibrinklebung. Langenbecks Arch. Chir. Suppl. Chir. 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Chemlizek F. Koller I. Heinerman M.:Endoscopic sealing of infected postoperative bronchus stump fistulae with fibrin sealant. Int. Cong. 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