{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:12:32Z","timestamp":1761559952298},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[1989,5,1]],"date-time":"1989-05-01T00:00:00Z","timestamp":609984000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1989,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>This retrospective review included 1,694 consecutive cases of colorectal carcinoma diagnosed at the University of Chicago Medical Center during a 25\u2010year period (1960 through 1984). The number and percentage of tumors occurring within 7 anatomic segments of the large bowel were determined. The statistical data for a recent 5\u2010year interval were then compared with those of the 2 preceding decades. There was a 10.2% increase in the frequency of cancers originating in the cecum or ascending colon, while rectal and rectosigmoid carcinomas declined by 15.8% during the same study period. These data provide further evidence for a progressive left\u2010to\u2010right shift in cancer distribution within the colon during the past quarter century. Currently, the most proximal and distal 20\u201325\u00a0cm segments of the large bowel (cecum or ascending colon versus rectum and rectosigmoid) each harbor approximately 25% of the tumors. Therefore, the classic medical teaching that over 50% of colorectal cancers would be detectable by digital examination and\/or proctosigmoidoscopy is no longer accurate. This documented increase in proximal colon cancers and redistribution of lesions within various large bowel segments indicate the growing importance of barium enema and colonoscopy as the optimal techniques for detection of colorectal neoplasms<\/jats:bold>.<\/jats:p>","DOI":"10.1007\/bf01659046","type":"journal-article","created":{"date-parts":[[2005,5,8]],"date-time":"2005-05-08T09:27:36Z","timestamp":1115544456000},"page":"321-324","source":"Crossref","is-referenced-by-count":28,"title":["Colorectal carcinomas: Diagnostic implications of their changing frequency and anatomic distribution"],"prefix":"10.1002","volume":"13","author":[{"given":"Gary G.","family":"Ghahremani","sequence":"first","affiliation":[{"name":"Department of Diagnostic Radiology Evanston Hospital Northwestern University 2650 Ridge Ave. 60201 Evanston Illinois USA"},{"name":"Departments of Surgery University of Chicago Hospitals and the Rush Medical College Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kambiz","family":"Dowlatshahi","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology Evanston Hospital Northwestern University 2650 Ridge Ave. 60201 Evanston Illinois USA"},{"name":"Departments of Surgery University of Chicago Hospitals and the Rush Medical College Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1989,5]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"1","article-title":"Cancer incidence and mortality in the United States","volume":"57","author":"Young J.L.","year":"1981","journal-title":"Natl. 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