{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T18:45:47Z","timestamp":1780944347156,"version":"3.54.1"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[1991,3,1]],"date-time":"1991-03-01T00:00:00Z","timestamp":667785600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1991,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Hepatic abscess\u2014amebic or pyogenic\u2014can be diagnosed with great accuracy by either ultrasonography or computed tomographic (CT) scanning. Ultrasound is the modality of choice and will detect almost 100% of abscesses. Confirmation of a diagnosis of amebic liver abscess is made by the indirect hemagglutination test that should be positive in almost 100% of cases. Cultures of pus from the abscess and from the blood must be obtained in cases of pyogenic liver abscess. A positive culture of pus from the abscess has been achieved in 90% of cases. Ultrasound or CT guidance is utilized in aspiration of a hepatic abscess<\/jats:bold>.<\/jats:p><jats:p><jats:bold>In the treatment of an amebic liver abscess, metronidazole is the amebicide of choice. Open drainage is contraindicated. For cases that fail to respond to therapy with amebicides, closed drainage guided by CT or ultrasound is performed. Secondary bacterial infection of an amebic liver abscess is an extremely rare event<\/jats:bold>.<\/jats:p><jats:p><jats:bold>The identification and determination of the antibiotic sensitivity of organisms responsible for pyogenic liver abscess is a crucially important step. Unless a celiotomy is necessary to correct an intraabdominal process or the abscess is extremely large, the initial treatment of pyogenic liver abscess is a 2 week course of appropriate antibiotics followed by a 1\u00a0month course of oral antibiotics. The majority of pyogenic liver abscesses will respond to such treatment. If drainage of a pyogenic abscess is required, the preferable technique is with a percutaneous CT\u2010 or ultrasound\u2010directed catheter. Open surgical drainage should be reserved for those cases in which a celiotomy is required for other purposes or for the patient who has failed a course of appropriate antibiotic therapy and closed percutaneous drainage is not feasible<\/jats:bold>.<\/jats:p><jats:p><jats:bold>The mortality for treatment of amebic liver abscess should be approximately zero and for pyogenic liver abscess should be less than 10%<\/jats:bold>.<\/jats:p>","DOI":"10.1007\/bf01659049","type":"journal-article","created":{"date-parts":[[2005,5,8]],"date-time":"2005-05-08T12:56:40Z","timestamp":1115557000000},"page":"162-169","source":"Crossref","is-referenced-by-count":58,"title":["Hepatic abscess"],"prefix":"10.1002","volume":"15","author":[{"given":"Arthur J.","family":"Donovan","sequence":"first","affiliation":[{"name":"Departments of Surgery and Radiology Los Angeles County University of Southern California Medical Center and the University of Southern California School of Medicine Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert E.","family":"Yellin","sequence":"additional","affiliation":[{"name":"Departments of Surgery and Radiology Los Angeles County University of Southern California Medical Center and the University of Southern California School of Medicine Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip W.","family":"Ralls","sequence":"additional","affiliation":[{"name":"Departments of Surgery and Radiology Los Angeles County University of Southern California Medical Center and the University of Southern California School of Medicine Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1991,3]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1987.01400220026003"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(81)80022-0"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198711000-00005"},{"key":"e_1_2_1_5_1","first-page":"235","article-title":"Diagnosis and treatment of amebic liver abscess","volume":"75","author":"Berne C.J.","year":"1942","journal-title":"Surg. Gynecol. Obstet."},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.145.1.7122867"},{"key":"e_1_2_1_7_1","first-page":"499","article-title":"Sonographic features of amebic and pyogenic liver abscesses: A blinded comparison","volume":"149","author":"Ralls P.W.","year":"1987","journal-title":"Am. J. Radiol."},{"key":"e_1_2_1_8_1","first-page":"1297","article-title":"CT of amebic liver abscess","volume":"150","author":"Radin D.R.","year":"1988","journal-title":"Am. J. Radiol."},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.149.2.6622702"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(19)32633-2"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(66)80021-1"},{"key":"e_1_2_1_12_1","volume-title":"Textbook of Surgery","author":"Rosoff L.","year":"1981"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1985.01390290037006"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(79)90210-5"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1965.14.540"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)32004-4"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)32923-9"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)32974-4"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(89)90316-4"},{"key":"e_1_2_1_20_1","first-page":"285","article-title":"Rupture of amoebic liver abscess into the peritoneal cavity: Certain points concerning its diagnosis and treatment","volume":"34","author":"Biggam A.G.","year":"1931","journal-title":"J. Trop. Med. Hygiene"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(38)90618-X"},{"key":"e_1_2_1_22_1","first-page":"460","article-title":"Amebic hepatitis and hepatic abscess","volume":"13","author":"Ochsner A.","year":"1943","journal-title":"Surgery"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.18004116606"},{"key":"e_1_2_1_24_1","first-page":"114","article-title":"Differentiation of pyogenic from amebic hepatic abscesses","volume":"162","author":"Conter R.L.","year":"1986","journal-title":"Surg. Gynecol. Obstet."}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01659049.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01659049\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/BF01659049","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T15:16:33Z","timestamp":1704986193000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/BF01659049"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,3]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1991,3]]}},"alternative-id":["10.1007\/BF01659049"],"URL":"https:\/\/doi.org\/10.1007\/bf01659049","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,3]]}}}