{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:10:00Z","timestamp":1786979400383,"version":"build-2736575974"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[1991,11,1]],"date-time":"1991-11-01T00:00:00Z","timestamp":688953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1991,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Twenty\u2010five patients with permanent postoperative hypoparathyroidism received cryopreserved parathyroid autografts. Twelve patients had undergone cervical re\u2010operations due to persistent or recurrent hyperparathyroidism and 10 patients had malfunction of a fresh autograft after total parathyroidectomy. Hypoparathyroidism occurred in 2 patients after subtotal parathyroidectomy and in 1 after the resection of a solitary adenoma following previous thyroid resection. The viability of the tissue was examined histologically prior to replantation in 22 patients and the amount of tissue needed for transplantation was determined by the ratio of necrotic cells vs. viable cells in the material. The patients were examined between 6\u00a0months and 125\u00a0months (median: 40\u00a0months) after replantation. Pre\u2010operatively each patient required high doses of calcium and vitamin D metabolites to establish normocalcemia. This medication was reduced postoperatively, with 16 patients requiring no supplemental treatment. Nine patients still needed low doses of calcium and\/or vitamin D. At follow\u2010up all patients were free of hypocalcemic symptoms. Our results demonstrate that replantation of autologous cryopreserved parathyroid tissue is safe and effective therapy for permanent postoperative hypoparathyroidism. Thus, we regard it as an essential part of today's parathyroid surgery.<\/jats:p>","DOI":"10.1007\/bf01665310","type":"journal-article","created":{"date-parts":[[2005,5,9]],"date-time":"2005-05-09T01:56:58Z","timestamp":1115603818000},"page":"751-755","source":"Crossref","is-referenced-by-count":54,"title":["Replantation of cryopreserved human parathyroid tissue"],"prefix":"10.1002","volume":"15","author":[{"given":"Peter K.","family":"Wagner","sequence":"first","affiliation":[{"name":"Department of Surgery Philipps University Marburg Federal Republic of Germany"},{"name":"Klinik f\u00fcr Allgemeinchirurgie Baidingerstra\u00dfe D\u20103550 Marburg Federal Republic of Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hinrich G.","family":"Seesko","sequence":"additional","affiliation":[{"name":"Department of Surgery Philipps University Marburg Federal Republic of Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Rothmund","sequence":"additional","affiliation":[{"name":"Department of Surgery Philipps University Marburg Federal Republic of Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1991,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1985.27"},{"key":"e_1_2_1_3_1","first-page":"646","article-title":"Histomorphometrische und ultrastrukurelle Skelletver\u00e4nderungen beim prim\u00e4ren Hyperparathyreoidismus","volume":"28","author":"Delling G.","year":"1978","journal-title":"Therapiewoche"},{"key":"e_1_2_1_4_1","first-page":"86","article-title":"The successful transplantation of frozen parathyroid tissue in man","volume":"81","author":"Wells S.A.","year":"1977","journal-title":"Surgery"},{"key":"e_1_2_1_5_1","first-page":"206","volume-title":"Hyperparathyroidism","author":"Wagner P.K.","year":"1986"},{"key":"e_1_2_1_6_1","first-page":"720","article-title":"Vereinfachtes Lagerungsverfahren von k\u00e4ltekonserviertem menschlichen Nebenschilddr\u00fcsengewebe","volume":"61","author":"Wagner P.K.","year":"1990","journal-title":"Chirurg"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198803000-00014"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1210\/edrv-3-3-245"},{"key":"e_1_2_1_9_1","first-page":"378","article-title":"Reoperation for secondary hyperparathyroidism in hemodialyzed patients","volume":"10","author":"Dubost C.","year":"1980","journal-title":"World J. 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