{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T12:56:54Z","timestamp":1777294614954,"version":"3.51.4"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[1991,7,1]],"date-time":"1991-07-01T00:00:00Z","timestamp":678326400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1991,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Continuous hyperthermic peritoneal perfusion (CHPP) with anticancer agents (mitomycin C and cisplatin) in warm saline was performed in patients with peritoneal dissemination of gastric cancer following resection of the primary lesion. The effect of CHPP was examined by a second\u2010look operation. This study includes 41 cases of gastric cancer with peritoneal dissemination but without liver metastasis treated during the past 6 years. The overall median survival was 14.6\u00a0months to 64.2\u00a0months from CHPP to death and the 3\u2010year survival rate was 28.5%. Second look surgery revealed a remarkable diminution in the degree of peritoneal dissemination in 7 (50%) of 14 patients with disappearance of ascites after only one course of CHPP in 7 (77.8%) of 9 patients. Long\u2010term 3 year\u2010survival was noted in 4 (9.8%) patients on CHPP. Side effects were renal insufficiency in 2 (5%) patients, leukopenia in 2 (5%) patients, and perforation of the small intestine in 1 (2%) patient. These results suggest the effectiveness of CHPP in the treatment of gastric cancer with peritoneal dissemination<\/jats:bold>.<\/jats:p>","DOI":"10.1007\/bf01675656","type":"journal-article","created":{"date-parts":[[2005,5,11]],"date-time":"2005-05-11T11:08:26Z","timestamp":1115809706000},"page":"530-535","source":"Crossref","is-referenced-by-count":103,"title":["Hyperthermo\u2010chemotherapy combined with cytoreductive surgery for the treatment of gastric cancer with peritoneal dissemination"],"prefix":"10.1002","volume":"15","author":[{"given":"Yutaka","family":"Yonemura","sequence":"first","affiliation":[{"name":"Surgery II School of Medicine Kanazawa University Kanazawa City Ishikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Fujimura","sequence":"additional","affiliation":[{"name":"Surgery II School of Medicine Kanazawa University Kanazawa City Ishikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sachio","family":"Fushida","sequence":"additional","affiliation":[{"name":"Surgery II School of Medicine Kanazawa University Kanazawa City Ishikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"Takegawa","sequence":"additional","affiliation":[{"name":"Surgery II School of Medicine Kanazawa University Kanazawa City Ishikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toru","family":"Kamata","sequence":"additional","affiliation":[{"name":"Surgery II School of Medicine Kanazawa University Kanazawa City Ishikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanji","family":"Katayama","sequence":"additional","affiliation":[{"name":"Surgery II School of Medicine Kanazawa University Kanazawa City Ishikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeo","family":"Kosaka","sequence":"additional","affiliation":[{"name":"Surgery II School of Medicine Kanazawa University Kanazawa City Ishikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akio","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Surgery II School of Medicine Kanazawa University Kanazawa City Ishikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kouichi","family":"Miwa","sequence":"additional","affiliation":[{"name":"Surgery II School of Medicine Kanazawa University Kanazawa City Ishikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ituo","family":"Miyazaki","sequence":"additional","affiliation":[{"name":"Surgery II School of Medicine Kanazawa University Kanazawa City Ishikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1991,7]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"189","volume-title":"Cancer of the Stomach","author":"Srivastava A.","year":"1986"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19870115)59:2<245::AID-CNCR2820590212>3.0.CO;2-K"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1986.4.9.1348"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19890701)64:1<154::AID-CNCR2820640126>3.0.CO;2-8"},{"key":"e_1_2_1_6_1","first-page":"1415","article-title":"Continuous hyperthermic peritoneal perfusion with cisplatin and mitomycin C for peritoneal dissemination in gastric cancer","volume":"24","author":"Fujimura T.","year":"1989","journal-title":"J. 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