{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T06:39:15Z","timestamp":1759991955192},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[1998,6,1]],"date-time":"1998-06-01T00:00:00Z","timestamp":896659200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur. J. Clin. Microbiol. Infect. Dis."],"published-print":{"date-parts":[[1998,6]]},"DOI":"10.1007\/bf01691579","type":"journal-article","created":{"date-parts":[[2005,5,15]],"date-time":"2005-05-15T06:50:19Z","timestamp":1116139819000},"page":"434-440","source":"Crossref","is-referenced-by-count":29,"title":["Trovafloxacin versus amoxicillin\/clavulanic acid in the treatment of acute exacerbations of chronic obstructive bronchitis"],"prefix":"10.1007","volume":"17","author":[{"given":"P.","family":"L\u00e9ophonte","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. J. T.","family":"Baldwin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Pluck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF01691579_CR1","first-page":"2","volume":"11","author":"MS Niederman","year":"1996","unstructured":"Niederman MS: Acute exacerbations of chronic bronchitis: the role of infection and the selection of appropriate therapy. Pulmonary and Critical Care Update (1996) 11:2\u20137","journal-title":"Pulmonary and Critical Care Update"},{"key":"BF01691579_CR2","first-page":"61","volume":"88","author":"P Ball","year":"1995","unstructured":"Ball P, Harris JM, Lowson D, Tillotson G, Wilson R: Acute infective exacerbations of chronic bronchitis. Quarterly Journal of Medicine (1995) 88:61\u201368","journal-title":"Quarterly Journal of Medicine"},{"issue":"Supplement 6A","key":"BF01691579_CR3","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0002-9343(91)90317-Q","volume":"91","author":"S Chodosh","year":"1991","unstructured":"Chodosh S: Treatment of chronic bronchitis: state of the art. American Journal of Medicine (1991) 91, Supplement 6A:87\u201392","journal-title":"American Journal of Medicine"},{"key":"BF01691579_CR4","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1164\/ajrccm\/142.5.1004","volume":"142","author":"J-Y Fagon","year":"1990","unstructured":"Fagon J-Y, Chastre J, Trouillet J-L, Domart Y, Dombret M-C, Bornet M, Gibert C: Characterization of distal bronchial microflora during acute exacerbation of chronic bronchitis: use of the protected specimen brush technique in 54 mechanically ventilated patients. American Reviews of Respiratory Disease (1990) 142:1004\u20131008","journal-title":"American Reviews of Respiratory Disease"},{"key":"BF01691579_CR5","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1093\/infdis\/134.6.552","volume":"134","author":"CB Smith","year":"1976","unstructured":"Smith CB, Golden C, Klauber MR, Kanner R, Renzetti A: Interactions between viruses and bacteria in patients with chronic bronchitis. Journal of Infectious Disease (1976) 134:552\u2013561","journal-title":"Journal of Infectious Disease"},{"key":"BF01691579_CR6","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1378\/chest.108.2_Supplement.53S","volume":"108","author":"R Wilson","year":"1995","unstructured":"Wilson R: Outcome predictors in bronchitis. Chest (1995) 108:53\u201357","journal-title":"Chest"},{"key":"BF01691579_CR7","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1001\/jama.1995.03520360071042","volume":"273","author":"S Saint","year":"1975","unstructured":"Saint S, Bent S, Vittinghoff E, Grady D: Antibiotics in chronic obstructive pulmonary disease exacerbations: a meta-analysis. Journal of the American Medical Association (1975) 273:957\u2013960","journal-title":"Journal of the American Medical Association"},{"key":"BF01691579_CR8","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/S0149-2918(96)80024-5","volume":"18","author":"ME P\u00e9rez-Gonzalvo","year":"1996","unstructured":"P\u00e9rez-Gonzalvo ME, Mosquera-Pesta\u00f1a JA, Ramos D, Apil\u00e1nez J, Borja J, Arnau C, Garc\u00eda-Barbal J, Mar\u00edn-Pardo J, on behalf of the Study of Ofloxacin in Lower Respiratory Tract Infections Research Group: Ofloxacin versus trimethoprim-sulfamethoxazole in the treatment of patients with acute exacerbation of chronic bronchitis. Clinical Therapeutics (1996) 18:440\u2013447","journal-title":"Clinical Therapeutics"},{"key":"BF01691579_CR9","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1179\/joc.1995.7.5.432","volume":"7","author":"M Cazzola","year":"1995","unstructured":"Cazzola M, Vinciguerra A, Beghi GF, Paizis G, Giura R, Madonini V, Fiorentini F, Consigli GF, Tonna M, Casalini A: Comparative evaluation of the clinical and microbiological efficacy of co-amoxiclav vs cefixime or ciprofloxacin in bacterial exacerbation of chronic bronchitis. Journal of Chemotherapy (1995) 7:432\u2013441","journal-title":"Journal of Chemotherapy"},{"key":"BF01691579_CR10","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/BF01780772","volume":"22","author":"A Polubiec","year":"1994","unstructured":"Polubiec A, Jorasz I, Pietrzak J, Soszka A, Stepka K, Zaryn A: A randomized study comparing low-dose ciprofloxacin and ofloxacin in the treatment of lower respiratory tract infections. Infection (1994) 22:62\u201364","journal-title":"Infection"},{"key":"BF01691579_CR11","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1007\/BF01691573","volume":"17","author":"J-C Pech\u00e8re","year":"1998","unstructured":"Pech\u00e8re J-C, Gootz TD: Bacteriological activity of trovafloxacin, a new quinolone, against respiratory tract pathogens. European Journal of Clinical Microbiology & Infectious Diseases (1998) 17:405\u2013412","journal-title":"European Journal of Clinical Microbiology & Infectious Diseases"},{"key":"BF01691579_CR12","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/S0891-5520(20)30693-0","volume":"9","author":"EF Hendershot","year":"1995","unstructured":"Hendershot EF: Fluoroquinolones. Infectious Disease Clinics of North America (1995) 9:715\u2013730","journal-title":"Infectious Disease Clinics of North America"},{"key":"BF01691579_CR13","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1136\/bmj.295.6602.814","volume":"295","author":"J Cockburn","year":"1987","unstructured":"Cockburn J, Gibberd RW, Reid AL, Sanson-Fisher RW: Determinants of non-compliance with short term antibiotic regimens. British Medical Journal (1987) 295:814\u2013818","journal-title":"British Medical Journal"},{"key":"BF01691579_CR14","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1128\/AAC.38.11.2615","volume":"38","author":"HC Neu","year":"1994","unstructured":"Neu HC, Chin N-X: In vitro activity of the new fluoroquinolone CP-99,219. Antimicrobial Agents and Chemotherapy (1994) 38:2615\u20132622","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF01691579_CR15","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1128\/AAC.40.4.1048","volume":"40","author":"GE Kenny","year":"1996","unstructured":"Kenny GE, Cartwright FD: Susceptibilities ofMycoplasma pneumoniae, Mycoplasma hominis, andUreaplasma urealyticum to a new quinolone, trovafloxacin (CP-99,219). Antimicrobial Agents and Chemotherapy (1996) 40:1048\u20131049","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF01691579_CR16","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1093\/jac\/35.6.869","volume":"35","author":"J Child","year":"1995","unstructured":"Child J, Andrews J, Boswell F, Brenwald N, Wise R: The in vitro activity of CP-99,219, a new naphthyridone antimicrobial agent: a comparison with fluoroquinolone agents. Journal of Antimicrobial Chemotherapy (1995) 35:869\u2013876","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"BF01691579_CR17","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1093\/jac\/37.5.955","volume":"37","author":"R Teng","year":"1996","unstructured":"Teng R, Liston TE, Harris SC: Multiple-dose pharmacokinetics and safety of trovafloxacin in healthy volunteers. Journal of Antimicrobial Chemotherapy (1996) 37:955\u2013963","journal-title":"Journal of Antimicrobial Chemotherapy"},{"issue":"Supplement B","key":"BF01691579_CR18","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1093\/jac\/39.6.797","volume":"39","author":"JM Andrews","year":"1997","unstructured":"Andrews JM, Honeybourne D, Brenwald NP, Bannerjee D, Iredale M, Cunningham D, Wise R: Concentrations of trovafloxacin in bronchial mucosa, epithelial lining fluid, alveolar macrophages and serum after administration of single or multiple oral doses to patients undergoing fibre-optic bronchoscopy. Journal of Antimicrobial Chemotherapy (1997) 39, Supplement B: 797\u2013802","journal-title":"Journal of Antimicrobial Chemotherapy"},{"issue":"Supplement 1","key":"BF01691579_CR19","first-page":"16","volume":"7","author":"PG Behler","year":"1995","unstructured":"Behler PG, Boge K, Bohning W, Gams W, Gartner-Toth M, Wettengel R: Amoxicillin\/clavulanic acid vs cefetamet pivoxil in the treatment of acute exacerbation of chronic bronchitis (AECB) in adults. Journal of Chemotherapy (1995) 7, Supplement 1:16\u201320","journal-title":"Journal of Chemotherapy"},{"issue":"Supplement E","key":"BF01691579_CR20","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1093\/jac\/26.suppl_E.63","volume":"26","author":"P Periti","year":"1990","unstructured":"Periti P, Novelli A, Schildwachter G, Schmidt-Gayk H, Ryo Y, Zuck P: Efficacy and tolerance of cefpodoxime proxetil compared with co-amoxiclav in the treatment of exacerbations of chronic bronchitis. Journal of Antimicrobial Chemotherapy (1990) 26, Supplement E: 63\u201369","journal-title":"Journal of Antimicrobial Chemotherapy"},{"issue":"Supplement D","key":"BF01691579_CR21","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1093\/jac\/26.suppl_D.75","volume":"26","author":"CM Rademaker","year":"1990","unstructured":"Rademaker CM, Sips AP, Beumer HM, Hoepelman IM, Overbeek BP, Mollers MJ, Rozenberg-Arska M, Verhoef J: A double-blind comparison of low-dose ofloxacin and amoxicillin\/clavulanic acid in acute exacerbations of chronic bronchitis. Journal of Antimicrobial Chemotherapy (1990) 26, Supplement D: 75\u201381","journal-title":"Journal of Antimicrobial Chemotherapy"},{"issue":"Supplement A","key":"BF01691579_CR22","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1093\/jac\/37.suppl_A.93","volume":"37","author":"L Allegra","year":"1996","unstructured":"Allegra L, Komnietzko N, Leophonte PJ, Pauwels R, Guyen JM, Petitpretz P: Comparative safety and efficacy of sparfloxacin in the treatment of acute exacerbations of chronic obstructive pulmonary disease: a double-blind, randomised, parallel, multicentre study. Journal of Antimicrobial Chemotherapy (1996) 37, Supplement A:93\u2013104","journal-title":"Journal of Antimicrobial Chemotherapy"},{"issue":"Supplement 6B","key":"BF01691579_CR23","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0002-9343(99)80303-9","volume":"99","author":"GV Doern","year":"1995","unstructured":"Doern GV: Trends in antimicrobial susceptibility of bacterial pathogens of the respiratory tract. American Journal of Medicine (1995) 99, Supplement 6B: 3\u20137","journal-title":"American Journal of Medicine"},{"key":"BF01691579_CR24","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1093\/jac\/37.4.803","volume":"37","author":"AM Sefton","year":"1996","unstructured":"Sefton AM, Maskell JP, Seymour AC, Minassian M, Williams JD: Comparative in-vitro activity of CP-99219, a new quinolone, against respiratory pathogens. Journal of Antimicrobial Chemotherapy (1996) 37:803\u2013808","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"BF01691579_CR25","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/j.1365-2125.1995.tb04453.x","volume":"39","author":"KT Batty","year":"1995","unstructured":"Batty KT, Davis TM, Ilett KF, Dusci LJ, Langton SP: The effect of ciprofloxacin on theophylline pharmacokinetics in healthy subjects. British Journal of Clinical Pharmacology (1995) 39:305\u2013311","journal-title":"British Journal of Clinical Pharmacology"},{"issue":"Supplement B","key":"BF01691579_CR26","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1093\/jac\/39.suppl_2.81","volume":"39","author":"J Vincent","year":"1997","unstructured":"Vincent J, Teng R, Dogolo LC, Willavize SA, Friedman HL: Effect of trovafloxacin, a new fluoroquinolone antibiotic, on the steady-state pharmacokinetics of theophylline in healthy volunteers. Journal of Antimicrobial Chemotherapy (1997) 39, Supplement B:81\u201386","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"BF01691579_CR27","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/BF01691581","volume":"17","author":"F Tr\u00e9moli\u00e8res","year":"1998","unstructured":"Tr\u00e9moli\u00e8res F, de Kock F, Pluck N, Daniel R: Trovafloxacin versus high-dose amoxicillin (1 g three times daily) in the treatment of community-acquired bacterial pneumonia: results of a multicentre, double-blind study. European Journal of Clinical Microbiology & Infectious Diseases (1998) 17:447\u2013453","journal-title":"European Journal of Clinical Microbiology & Infectious Diseases"}],"container-title":["European Journal of Clinical Microbiology &amp; Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01691579.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01691579\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01691579","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,11]],"date-time":"2021-07-11T00:24:43Z","timestamp":1625963083000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01691579"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,6]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1998,6]]}},"alternative-id":["BF01691579"],"URL":"https:\/\/doi.org\/10.1007\/bf01691579","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,6]]}}}