{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T04:49:40Z","timestamp":1770698980967,"version":"3.49.0"},"reference-count":75,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1995,3,1]],"date-time":"1995-03-01T00:00:00Z","timestamp":794016000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intensive Care Med"],"published-print":{"date-parts":[[1995,3]]},"DOI":"10.1007\/bf01701489","type":"journal-article","created":{"date-parts":[[2005,6,10]],"date-time":"2005-06-10T21:04:49Z","timestamp":1118437489000},"page":"277-285","source":"Crossref","is-referenced-by-count":161,"title":["Neutrophil-mediated tissue injury and its modulation"],"prefix":"10.1007","volume":"21","author":[{"given":"S.","family":"Fujishima","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Aikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF01701489_CR1","doi-asserted-by":"crossref","unstructured":"ACCP\/SCCM Consensus Conference Committee (1992) Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 101:1644\u20131655","DOI":"10.1378\/chest.101.6.1644"},{"key":"BF01701489_CR2","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/S0140-6736(85)92312-8","volume":"I","author":"S Braude","year":"1985","unstructured":"Braude S, Apperley J, Krausz T, Goldman JM, Royston D (1985) Adult respiratory distress syndrome after allogenic bone-marrow transplantation: Evidence for a neutrophil-independent mechanism. Lancet, I:1239\u20131242","journal-title":"Lancet"},{"key":"BF01701489_CR3","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1056\/NEJM198608283150904","volume":"315","author":"FP Ognibene","year":"1986","unstructured":"Ognibene FP, Martin SE, Parker MM, Schlesinger T, Roach P, Burch C, Shelhamer JH, Parrillo JE (1986) Adult respiratory distress syndrome in patients with severe neutropenia. N Engl J Med 315:547\u2013551","journal-title":"N Engl J Med"},{"key":"BF01701489_CR4","first-page":"313","volume":"133","author":"RJ Maunder","year":"1986","unstructured":"Maunder RJ, Hackman RC, Riff E, Albert RK, Springmeyer SC (1986) Occurrence of the adult respiratory distress syndrome in neutropenic patients. Am Rev Respir Dis 133:313\u2013316","journal-title":"Am Rev Respir Dis"},{"key":"BF01701489_CR5","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0272-5231(21)00140-4","volume":"3","author":"TL Petty","year":"1982","unstructured":"Petty TL (1982) Adult respiratory distress syndrome: Definition and historical perspective. Clin Chest Med 3:3\u20137","journal-title":"Clin Chest Med"},{"key":"BF01701489_CR6","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1164\/ajrccm\/137.4.783","volume":"137","author":"A Ishizaka","year":"1988","unstructured":"Ishizaka A, Stephens K, Tazelaar HD, Hall EW, O'Hanley P, Raffin TA (1988) Pulmonary edema afterE. coli peritonitis correlates with thiobarbituric acid reactive materials in bronchoalveolar lavage fluid. Am Rev Respir Dis 137:783\u2013789","journal-title":"Am Rev Respir Dis"},{"key":"BF01701489_CR7","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1172\/JCI110371","volume":"68","author":"AC Heflin","year":"1981","unstructured":"Heflin AC, Brigham KL (1981) Prevention by granulocyte depletion of increased vascular permeability of sheep lung following endotoxemia. J Clin Invest 68:1253\u20131260","journal-title":"J Clin Invest"},{"key":"BF01701489_CR8","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1172\/JCI113431","volume":"81","author":"S Okusawa","year":"1988","unstructured":"Okusawa S, Gelfand JA, Ikejima T, Connolly RJ, Dinarello CA (1988) Interleukin I induces a shock-like state in rabbits. J Clin Invest 81:1162\u20131172","journal-title":"J Clin Invest"},{"key":"BF01701489_CR9","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1126\/science.3764421","volume":"234","author":"KJ Tracey","year":"1986","unstructured":"Tracey KJ, Beutler B, Lowry SF, Merryweather J, Wolpe S, Milsark LW, Hariri RJ, Fahey III TJ, Zentella A, Albert JD, Shires GT, Cerami A (1986) Shock and tissue injury induced by recombinant human cachectin. Science 234:470\u2013474","journal-title":"Science"},{"key":"BF01701489_CR10","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1164\/ajrccm\/138.5.1300","volume":"138","author":"KE Stephens","year":"1988","unstructured":"Stephens KE, Ishizaka A, Wu ZH, Larrick JW, Raffin TA (1988) Granulocyte depletion prevents TNF-mediated acute lung injury in guinea pigs. Am Rev Respir Dis 138:1300\u20131307","journal-title":"Am Rev Respir Dis"},{"key":"BF01701489_CR11","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1084\/jem.167.6.1883","volume":"167","author":"K Matsushima","year":"1988","unstructured":"Matsushima K, Morishita K, Yoshimura T, Lavu S, Kobayashi Y, Lee W, Appella E, Kung HF, Leonard EJ, Oppenheim JJ (1988) Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor. J Exp Med 167:1883\u20131893","journal-title":"J Exp Med"},{"key":"BF01701489_CR12","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/0140-6736(93)90416-E","volume":"341","author":"SC Donnelly","year":"1993","unstructured":"Donnelly SC, Strieter RM, Kunkel SL, Walz A, Robertson CR, Carter DC, Grant IS, Pollok AJ, Haslett C (1993) Interleukin-8 and development of adult respiratory distress syndrome in at-risk patient groups. Lancet 341:643\u2013647","journal-title":"Lancet"},{"key":"BF01701489_CR13","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0140-6736(93)92325-N","volume":"342","author":"S Fujishima","year":"1993","unstructured":"Fujishima S, Sasaki J, Shinozawa Y, Takuma K, Hori S, Aikawa N (1993) Interleukin 8 in ARDS. Lancet 342:237\u2013238","journal-title":"Lancet"},{"key":"BF01701489_CR14","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1161\/01.RES.67.1.68","volume":"67","author":"DC Hocking","year":"1990","unstructured":"Hocking DC, Phillips PG, Ferro TJ, Johnson A (1990) Mechanisms of pulmonary edema induced by TNF. Circ Res 67:68\u201377","journal-title":"Circ Res"},{"key":"BF01701489_CR15","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1159\/000234610","volume":"86","author":"A Ferrante","year":"1988","unstructured":"Ferrante A, Nandoskar M, Walz A, Goh DH, Kowanko IC (1988) Effects of tumor necrosis factor alpha and interleukin-1 alpha and beta on human neutrophil migration, respiratory burst and degranulation. Int Arch Allergy Appl Immunol 86:82\u201391","journal-title":"Int Arch Allergy Appl Immunol"},{"key":"BF01701489_CR16","doi-asserted-by":"crossref","first-page":"857","DOI":"10.4049\/jimmunol.130.2.857","volume":"130","author":"C Dahinden","year":"1983","unstructured":"Dahinden C, Galanos C, Fehr J (1983) Granulocyte activation by endotoxin I. Correlation between adherence and other granulocyte functions, and role of endotoxin structure on biologic activity. J Immunol 130:857\u2013862","journal-title":"J Immunol"},{"key":"BF01701489_CR17","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1126\/science.1698311","volume":"249","author":"SD Wright","year":"1990","unstructured":"Wright SD, Ramos RA, Tobias PS, Ulevitch RJ, Mathison JC (1990) CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249:1431\u20131433","journal-title":"Science"},{"key":"BF01701489_CR18","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0162-3109(80)90050-8","volume":"2","author":"RO Webster","year":"1980","unstructured":"Webster RO, Hong SR, Johnston RB Jr, Henson PM (1980) The biological effects of the human complement fragments C5a and C5a desarg on neutrophil function. Immunopharmacology 2:201\u2013219","journal-title":"Immunopharmacology"},{"key":"BF01701489_CR19","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1073\/pnas.72.3.1059","volume":"72","author":"E Schiffman","year":"1975","unstructured":"Schiffman E, Corcoran BA, Wahl SA (1975) N-formylmethionyl peptides as chemoattractants for leukocytes. Proc Natl Acad Sci USA 72:1059\u20131062","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF01701489_CR20","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1084\/jem.167.5.1547","volume":"167","author":"P Peveri","year":"1988","unstructured":"Peveri P, Walz A, Dewald B, Baggiolini M (1988) A novel neutrophil-activating factor produced by human mononuclear phagocytes. J Exp Med 167:1547\u20131559","journal-title":"J Exp Med"},{"key":"BF01701489_CR21","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1126\/science.6390681","volume":"226","author":"JC Gasson","year":"1984","unstructured":"Gasson JC, Weisbart RH, Kaufman SE, Clark SC, Hewick RM, Wong GG (1984) Purified human granulocytemacrophage colony-stimulating factor: Direct action on neutrophils. Science 226:1339\u20131342","journal-title":"Science"},{"key":"BF01701489_CR22","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1128\/IAI.58.6.1647-1652.1990","volume":"58","author":"Y Ichinose","year":"1990","unstructured":"Ichinose Y, Hara N, Ohta M, Aso H, Chikama H, Kawasaki M, Kubota I, Shimizu T, Yagawa K (1990) Recombinant granulocyte colony-stimulating factor and liopolysaccharide maintain the phenotype of and superoxide anion generation by neutrophils. Infect Immun 58:1647\u20131652","journal-title":"Infect Immun"},{"key":"BF01701489_CR23","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.4049\/jimmunol.135.3.2069","volume":"135","author":"MR Shalaby","year":"1985","unstructured":"Shalaby MR, Aggarwal, BB, Rinderknecht E, Svedersky LP, Finkle BS, Palladino MA Jr (1985) Activation of human polymorphonuclear neutrophil functions by interferon-\u03b3 and tumor necrosis factors. J Immunol 135:2069\u20132073","journal-title":"J Immunol"},{"key":"BF01701489_CR24","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1038\/286264a0","volume":"286","author":"AW Ford-Hutchinson","year":"1980","unstructured":"Ford-Hutchinson AW, Bray MA, Doing MV, Shipley ME, Smith JH (1980) Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes. Nature 286:264\u2013265","journal-title":"Nature"},{"key":"BF01701489_CR25","doi-asserted-by":"crossref","first-page":"16168","DOI":"10.1016\/S0021-9258(18)41982-5","volume":"267","author":"S Fiore","year":"1992","unstructured":"Fiore S, Ryeom SW, Weller PF, Serhan CN (1992) Lipoxin recognition sites. J Biol Chem 267:16168\u201316176","journal-title":"J Biol Chem"},{"key":"BF01701489_CR26","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1182\/blood.V71.1.159.159","volume":"71","author":"JC Gay","year":"1988","unstructured":"Gay JC, Stitt ES (1988) Platelet-activating factor induces protein kinase activity in the particulate fraction of human neutrophils. Blood 71:159\u2013165","journal-title":"Blood"},{"key":"BF01701489_CR27","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1172\/JCI114249","volume":"84","author":"M F\u00e4llma","year":"1989","unstructured":"F\u00e4llma M, Lew DP, Stendahl O, Andersson T (1989) Receptor-mediated phagocytosis in human neutrophils is associated with increased formation of inositol phosphates and diacylglycerol. J Clin Invest 84:886\u2013891","journal-title":"J Clin Invest"},{"key":"BF01701489_CR28","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/0167-5699(92)90159-5","volume":"13","author":"R Pardi","year":"1992","unstructured":"Pardi R, Inverardi L, Bender JR (1992) Regulatory mechanisms in leukocyte adhesion: flexible receptors for sophisticated travelers. Immunol Today 13:224\u2013229","journal-title":"Immunol Today"},{"key":"BF01701489_CR29","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1083\/jcb.109.3.1341","volume":"109","author":"C Nathan","year":"1989","unstructured":"Nathan C, Srimal S, Farber C, Sanchez E, Kabbash L, Asch A, Gailit J, Wright SD (1989) Cytokine-induced respiratory burst and CD11\/CD18 integrins. J Cell Biol 109:1341\u20131349","journal-title":"J Cell Biol"},{"key":"BF01701489_CR30","doi-asserted-by":"crossref","first-page":"3659","DOI":"10.4049\/jimmunol.143.11.3659","volume":"143","author":"M Cluzel","year":"1989","unstructured":"Cluzel M, Undem BJ, Chilton FH (1989) Release of platelet-activating factor and the metabolism of leukotriene B4 by the human neutrophil when studied in a cell superfusion model. J Immunol 143:3659\u20133665","journal-title":"J Immunol"},{"key":"BF01701489_CR31","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0006-291X(84)80066-2","volume":"122","author":"SM Prescott","year":"1984","unstructured":"Prescott SM, Zimmerman GA, Seeger AR (1984) Leukotriene B4 is an incomplete agonist for the activation of human neutrophils. Biochem Biophys Res Commun 122:535\u2013541","journal-title":"Biochem Biophys Res Commun"},{"key":"BF01701489_CR32","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/BF01978732","volume":"11","author":"PM Henson","year":"1981","unstructured":"Henson PM (1981) Platelet activating factor (PAF) as a mediator of neutrophil-platelet interactions in inflammation. Agents Action 11:545\u2013547","journal-title":"Agents Action"},{"key":"BF01701489_CR33","doi-asserted-by":"crossref","first-page":"2748","DOI":"10.4049\/jimmunol.135.4.2748","volume":"135","author":"F Bussolino","year":"1985","unstructured":"Bussolino F, Aglietta M, Sanavio F, Stacchini A, Lauri D, Camussi G (1985) Alkylether phosphoglycerides influence calcium fluxes into human endothelial cells. J Immunol 135:2748\u20132755","journal-title":"J Immunol"},{"key":"BF01701489_CR34","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1084\/jem.128.5.1137","volume":"128","author":"A Janoff","year":"1968","unstructured":"Janoff A, Scherer J (1968) Mediators of inflammation in leukocyte lysosomes. IX. Elastinolytic activity in granules of human polymorphonuclear leukocytes. J Exp Med 128:1137\u20131155","journal-title":"J Exp Med"},{"key":"BF01701489_CR35","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1016\/S0006-291X(80)80110-0","volume":"95","author":"JE Gadek","year":"1980","unstructured":"Gadek JE, Fells GA, Wright DG, Crystal RG (1980) Human neutrophil elastase functions as a type III collagen collagenase. Biochem Biophys Res Commun 95:1815\u20131822","journal-title":"Biochem Biophys Res Commun"},{"key":"BF01701489_CR36","doi-asserted-by":"crossref","first-page":"5435","DOI":"10.1016\/S0021-9258(19)70805-9","volume":"255","author":"CL Mainardi","year":"1980","unstructured":"Mainardi CL, Dixit SN, Kang AH (1980) Degradation of type IV (basement membrane) collagen by a proteinase isolated from human polymorphonuclear leukocyte granules. J Biol Chem 255:5435\u20135441","journal-title":"J Biol Chem"},{"key":"BF01701489_CR37","doi-asserted-by":"crossref","first-page":"8848","DOI":"10.1016\/S0021-9258(18)43580-6","volume":"255","author":"JA McDonald","year":"1980","unstructured":"McDonald JA, Kelley DG (1980) Degradation of fibronectin by leukocytes elastase. Release of biologically active fragments. J Biol Chem 255:8848\u20138858","journal-title":"J Biol Chem"},{"key":"BF01701489_CR38","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/j.1432-1033.1983.tb07118.x","volume":"130","author":"HW Macartney","year":"1983","unstructured":"Macartney HW, Tschesche H (1983) Latent and active human polymorphonuclear leukocyte collagenases. Isolation, purification and characterization. Eur J Biochem 130:71\u201378","journal-title":"Eur J Biochem"},{"key":"BF01701489_CR39","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1172\/JCI110643","volume":"70","author":"B Dewald","year":"1982","unstructured":"Dewald B, Bretz U, Baggiolini M (1982) Release of gelatinase from a novel secretory compartment of human neutrophils. J Clin Invest 70:518\u2013525","journal-title":"J Clin Invest"},{"key":"BF01701489_CR40","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1172\/JCI112104","volume":"76","author":"Y Matzner","year":"1985","unstructured":"Matzner Y, Barner M, Yahalom J, Ishai-Michaeli R, Fuks Z, Vlodavsky I (1985) Degradation of haparan sulfate in the subendothelial extracellular matrix by a readily released haparanase from human neutrophils. Possible role in invasion through basement membranes. J Clin Invest 76:1306\u20131313","journal-title":"J Clin Invest"},{"key":"BF01701489_CR41","doi-asserted-by":"crossref","first-page":"15208","DOI":"10.1016\/S0021-9258(18)48159-8","volume":"262","author":"K Morishita","year":"1987","unstructured":"Morishita K, Tsuchiya M, Asano S, Kaziro Y, Nagata S (1987) Chromosomal gene structure of human myeloperoxidase and regulation of its expression by granulocyte colony-stimulating factor. J Biol Chem 262:15208\u201315213","journal-title":"J Biol Chem"},{"key":"BF01701489_CR42","doi-asserted-by":"crossref","first-page":"13479","DOI":"10.1016\/S0021-9258(18)68262-6","volume":"263","author":"PS Tobias","year":"1988","unstructured":"Tobias PS, Mathison JC, Ulevitch RJ (1988) A family of lipopolysaccharide binding proteins involved in responses to gram-negative sepsis. J Biol Chem 263:13479\u201313481","journal-title":"J Biol Chem"},{"key":"BF01701489_CR43","doi-asserted-by":"crossref","first-page":"4286","DOI":"10.4049\/jimmunol.140.12.4286","volume":"140","author":"RM Jack","year":"1988","unstructured":"Jack RM, Fearon DT (1988) Selective synthesis of mRNA and proteins by human peripheral blood neutrophils. J Immunol 140:4286\u20134293","journal-title":"J Immunol"},{"key":"BF01701489_CR44","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1002\/jcp.1041540305","volume":"154","author":"S Fujishima","year":"1993","unstructured":"Fujishima S, Hoffman AR, Vu T, Kim KJ, Xheng H, Daniek D, Kim Y, Wallace EF, Larrick JW, Raffin TA (1993) The regulation of neutrophil interleukin 8 gene expression and protein secretion by LPS, TNF-\u03b1 and IL-1\u03b2. J Cell Physiol 154:478\u2013485","journal-title":"J Cell Physiol"},{"key":"BF01701489_CR45","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1084\/jem.178.1.63","volume":"178","author":"T Kasama","year":"1993","unstructured":"Kasama T, Strieter RM, Standiford TJ, Burdick MD, Kunkel SL (1993) Expression and regulation of human neutrophil-derived macrophage inflammatory protein 1\u03b1. J Exp Med 178:63\u201372","journal-title":"J Exp Med"},{"key":"BF01701489_CR46","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1172\/JCI115134","volume":"87","author":"PCW Lord","year":"1991","unstructured":"Lord PCW, Wilmoth LMG, Mizel SB, McCall CE (1991) Expression of interleukin-1\u03b1 and \u03b2 genes by human blood polymorphonuclear leukocytes. J Clin Invest 87:1312\u20131321","journal-title":"J Clin Invest"},{"key":"BF01701489_CR47","doi-asserted-by":"crossref","first-page":"837","DOI":"10.4049\/jimmunol.140.3.837","volume":"140","author":"A Lindemann","year":"1988","unstructured":"Lindemann A, Riedel D, Oster W, Meuer SC, Blohm D, Mertelsmann RH, Herrmann F (1988) Granulocyte\/macrophage colony-stimulating factor induced interleukin 1 production by human polymorphonuclear neutrophils. J Immunol 140:837\u2013839","journal-title":"J Immunol"},{"key":"BF01701489_CR48","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1182\/blood.V75.10.2049.2049","volume":"75","author":"NA Cicco","year":"1990","unstructured":"Cicco NA, Lindemann A, Content J, Vandenbussche P, L\u00fcbbert M, Gauss J, Merteismann R, Hermann F (1990) Inducible production of interleukin-6 by human polymorphonuclear neutrophils. Role of granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha. Blood 75:2049\u20132052","journal-title":"Blood"},{"key":"BF01701489_CR49","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1084\/jem.173.3.771","volume":"173","author":"F Bazzoni","year":"1991","unstructured":"Bazzoni F, Cassatella MA, Rossi F, Ceska M, Dewald B, Baggiolini M (1991) Phagocytosing neutrophils produce and release high amounts of the neutrophil-activating peptide 1\/interleukin 8. J Exp Med 173:771\u2013774","journal-title":"J Exp Med"},{"key":"BF01701489_CR50","doi-asserted-by":"crossref","first-page":"6758","DOI":"10.1073\/pnas.87.17.6758","volume":"87","author":"DB Dubravec","year":"1990","unstructured":"Dubravec DB, Spriggs DR, Mannick JA, Rodrick ML (1990) Circulating human peripheral blood granulocytes synthesize and secrete tumor necrosis factor \u03b1. Proc Natl Acad Sci USA 87:6758\u20136761","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF01701489_CR51","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1182\/blood.V76.7.1405.1405","volume":"76","author":"JY Djeu","year":"1990","unstructured":"Djeu JY, Serbousek D, Blanchard DK (1990) Release of tumor necrosis factor by human polymorphonuclear leukocytes. Blood 76:1405\u20131409","journal-title":"Blood"},{"key":"BF01701489_CR52","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1182\/blood.V75.1.17.17","volume":"75","author":"N Shirafuji","year":"1990","unstructured":"Shirafuji N, Matsuda S, Ogura H, Tani K, Kodo H, Ozawa K, Nagata S, Asano S, Takaku F (1990) Granulocyte colonystimulating factor stimulates human mature neutrophilic granulocytes to produce interferon-\u03b1. Blood 75:17\u201319","journal-title":"Blood"},{"key":"BF01701489_CR53","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1172\/JCI114016","volume":"83","author":"A Lindemann","year":"1989","unstructured":"Lindemann A, Riedel D, Oster W, Ziegler-Heitbrock HWL (1989) Granulocyte-macrophage colony-stimulating factor induces cytokine secretion by human polymorphonuclear leukocytes. J Clin Invest 83:1308\u20131312","journal-title":"J Clin Invest"},{"key":"BF01701489_CR54","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1084\/jem.174.3.745","volume":"174","author":"H Kita","year":"1991","unstructured":"Kita H, Ohnishi T, Okubo Y, Weiler D, Abrams JS, Gleich GJ (1991) Granulocyte\/macrophage colony-stimulating factor and interleukin 3 release from human peripheral blood eosinophils and neutrophils. J Exp Med 174:745\u2013748","journal-title":"J Exp Med"},{"key":"BF01701489_CR55","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1002\/jcp.1041400226","volume":"140","author":"GR Grotendorst","year":"1989","unstructured":"Grotendorst GR, Smale G, Pencev D (1989) Production of transforming growth factor beta by human peripheral blood monocytes and neutrophils. J Cell Physiol 140:396\u2013402","journal-title":"J Cell Physiol"},{"key":"BF01701489_CR56","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1084\/jem.176.2.593","volume":"176","author":"SR McColl","year":"1992","unstructured":"McColl SR, Paquin R, M\u00e9nard C, Beaulieu A (1992) Human neutrophils produce high levels of the interleukin 1 receptor antagonist in response to granulocyte\/macrophage colony-stimulating factor and tumor necrosis factor \u03b1. J Exp Med 176:593\u2013598","journal-title":"J Exp Med"},{"key":"BF01701489_CR57","first-page":"390","volume":"12","author":"CJ Fisher Jr","year":"1993","unstructured":"Fisher Jr CJ, Dhainaut JF, Pribble JP, Pharm D, Knaus WA, Thompson RC, the IL-1ra Phase III Sepsis Syndrome Study Group (1993) A phase III multicenter trial of human recombinant interleukin-1 receptor antagonist (IL-1r\u03b1) in the treatment of patients with sepsis syndrome. Lymphokine Cytokine Res 12:390","journal-title":"Lymphokine Cytokine Res"},{"key":"BF01701489_CR58","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1001\/jama.1993.03500140081040","volume":"269","author":"CA Dinarello","year":"1993","unstructured":"Dinarello CA, Gelfand JA, Wolff SM (1993) Anticytokine strategies in the treatment of the systemic inflammatory response syndrome. JAMA 269:1829\u20131835","journal-title":"JAMA"},{"key":"BF01701489_CR59","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.4049\/jimmunol.151.3.1548","volume":"151","author":"KM Mohler","year":"1993","unstructured":"Mohler KM, Torrance DS, Smith CA, Goodwin RG, Stremler KE, Fung VP, Madani H, Widmer MB (1993) Soluble tumor necrosis factor (TNF), receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists. J Immunol 151:1548\u20131561","journal-title":"J Immunol"},{"key":"BF01701489_CR60","doi-asserted-by":"crossref","first-page":"7125","DOI":"10.1016\/S0021-9258(18)53154-9","volume":"268","author":"B Moser","year":"1993","unstructured":"Moser B, Dewald B, Barella L, Schumacher C, Baggiolini M, Clark-Lewis I (1993) Interleukin-8 antagonists generated by N-terminal modification. J Biol Chem 268:7125\u20137128","journal-title":"J Biol Chem"},{"key":"BF01701489_CR61","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1136\/bmj.304.6820.132","volume":"304","author":"CJ Hinds","year":"1992","unstructured":"Hinds CJ (1992) Monoclonal antibodies in sepsis and septic shock: recent progress, vast potential. BMJ 304:132\u2013133","journal-title":"BMJ"},{"key":"BF01701489_CR62","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1126\/science.8420003","volume":"259","author":"A Rustici","year":"1993","unstructured":"Rustici A, Velucchi M, Faggioni R, Sironi M, Ghezzi P, Quataert S, Green B, Porro M (1993) Molecular mapping and detoxification of the lipid A binding site by synthetic peptides. Science 259:361\u2013365","journal-title":"Science"},{"key":"BF01701489_CR63","doi-asserted-by":"crossref","first-page":"231","DOI":"10.4049\/jimmunol.152.1.231","volume":"152","author":"JW Larrick","year":"1994","unstructured":"Larrick JW, Hirata M, Zheng H, Bolin D, Cavaillon J, Warren HS, Wright SC (1994) A novel granulocyte-derived peptide with lipopolysaccharide-neutralizing activity. J Immunol 152:231\u2013240","journal-title":"J Immunol"},{"key":"BF01701489_CR64","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1164\/ajrccm\/139.6.1553","volume":"139","author":"SI Said","year":"1989","unstructured":"Said SI, Foda HD (1989) Pharmacologic modulation of lung injury. Am Rev Respir Dis 139:1553\u20131564","journal-title":"Am Rev Respir Dis"},{"key":"BF01701489_CR65","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1038\/349164a0","volume":"349","author":"SR Watson","year":"1991","unstructured":"Watson SR, Fennie C, Lasky LA (1991) Neutrophil influx into an inflammatory site inhibited by a soluble homing receptor-IgG chimaera. Nature 349:164\u2013167","journal-title":"Nature"},{"key":"BF01701489_CR66","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1172\/JCI115446","volume":"88","author":"MS Mulligan","year":"1991","unstructured":"Mulligan MS, Varani J, Dame MK, Lane CL, Smith CW, Anderson DC, Ward PA (1991) Role of endothelial-leukocyte adhesion molecule 1 (ELAM-1) in neutrophil-mediated lung injury in rats. J Clin Invest 88:1396\u20131406","journal-title":"J Clin Invest"},{"key":"BF01701489_CR67","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/S0021-9258(17)36058-1","volume":"261","author":"T Takenawa","year":"1986","unstructured":"Takenawa T, Ishitoya J, Nagai Y (1986) Inhibitory effect of prostaglandin E2, forskolin and dibutyryl cAMP on arachidonic acid release and inositol phospholipid metabolism in guinea pig neutrophils. J Biol Chem 261:1092\u20131098","journal-title":"J Biol Chem"},{"key":"BF01701489_CR68","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.4049\/jimmunol.135.2.1366","volume":"135","author":"BN Cronstein","year":"1985","unstructured":"Cronstein BN, Rosenstein ED, Kramer SB, Weissmann G, Hirschhorn R (1985) Adenosine; a physiologic modulator of superoxide anion generation by human neutrophils. Adenosine acts via an A2 receptor on human neutrophils. J Immunol 135:1366\u20131371","journal-title":"J Immunol"},{"key":"BF01701489_CR69","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1159\/000138831","volume":"43","author":"S Fujishima","year":"1991","unstructured":"Fujishima S, Kraft SA, McGuire GP, Raffin TA, Pearl RG (1991) Isoproterenol prevents oxidant-induced injury in isolated rabbit lungs. Pharmacology 43:78\u201383","journal-title":"Pharmacology"},{"key":"BF01701489_CR70","doi-asserted-by":"crossref","first-page":"2138","DOI":"10.1152\/jappl.1988.65.5.2138","volume":"65","author":"RE Parker","year":"1988","unstructured":"Parker RE, Hardin JR, Brigham KL (1988) Verapamil attenuates lung vascular responses to endotoxin in sheep. J Appl Physiol 65:2138\u20132143","journal-title":"J Appl Physiol"},{"key":"BF01701489_CR71","doi-asserted-by":"crossref","unstructured":"Claman H (1992) Corticosteroids as immunomodulators: In: Georgiev V, Yamaguchi H (eds) Immunodulating drugs. Ann New York Acad Sci 685:288\u2013292","DOI":"10.1111\/j.1749-6632.1993.tb35877.x"},{"key":"BF01701489_CR72","doi-asserted-by":"crossref","first-page":"4306","DOI":"10.4049\/jimmunol.151.8.4306","volume":"151","author":"M Perretti","year":"1993","unstructured":"Perretti M, Ahluwalia A, Harris JG, Goulding NJ, Flower RJ (1993) Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil-dependent edema in the mouse. J Immunol 151:4306\u20134314","journal-title":"J Immunol"},{"key":"BF01701489_CR73","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1164\/ajrccm\/140.2.531","volume":"140","author":"JE Heffner","year":"1989","unstructured":"Heffner JE, Repine JE (1989) Pulmonary strategies of antioxidant defense. Am Rev Respir Dis 140:531\u2013554","journal-title":"Am Rev Respir Dis"},{"key":"BF01701489_CR74","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1097\/00005373-199307000-00018","volume":"35","author":"I Marzi","year":"1993","unstructured":"Marzi I, B\u00fchren V, Sch\u00fcttler A, Trentz O (1993) Value of superoxide dismutase for prevention of multiple organ failure after multiple trauma. J Trauma 35:110\u2013120","journal-title":"J Trauma"},{"key":"BF01701489_CR75","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1126\/science.7687073","volume":"261","author":"N Zhu","year":"1993","unstructured":"Zhu N, Liggitt D, Liu Y, Debs R (1993) Systemic gene expression after intravenous DNA delivery into adult mice. Science 261:209\u2013211","journal-title":"Science"}],"container-title":["Intensive Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01701489.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01701489\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01701489","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T10:09:00Z","timestamp":1683108540000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01701489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,3]]},"references-count":75,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1995,3]]}},"alternative-id":["BF01701489"],"URL":"https:\/\/doi.org\/10.1007\/bf01701489","relation":{},"ISSN":["0342-4642","1432-1238"],"issn-type":[{"value":"0342-4642","type":"print"},{"value":"1432-1238","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,3]]}}}