{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T18:47:29Z","timestamp":1793126849935,"version":"4.5.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[1994,4,1]],"date-time":"1994-04-01T00:00:00Z","timestamp":765158400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intensive Care Med"],"published-print":{"date-parts":[[1994,4]]},"DOI":"10.1007\/bf01708961","type":"journal-article","created":{"date-parts":[[2005,6,12]],"date-time":"2005-06-12T08:10:18Z","timestamp":1118563818000},"page":"260-267","source":"Crossref","is-referenced-by-count":205,"title":["A new therapy of post-trauma brain oedema based on haemodynamic principles for brain volume regulation"],"prefix":"10.1007","volume":"20","author":[{"given":"B.","family":"Asgeirsson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. O.","family":"Gr\u00e4nde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. H.","family":"Nordstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF01708961_CR1","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1378\/chest.98.1.180","volume":"198","author":"C Borel","year":"1990","unstructured":"Borel C, Hanley D, Diringer MN, Rogers MC (1990) Intensive management of severe head injury. Chest 198:180\u2013189","journal-title":"Chest"},{"key":"BF01708961_CR2","first-page":"383","volume-title":"Edema","author":"JD Fenstermacher","year":"1984","unstructured":"Fenstermacher JD (1984) Volume regulation of the central nervous system. In: Staub NC, Taylor AE (eds) Edema. Raven Press, New York, pp 383\u2013404"},{"key":"BF01708961_CR3","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3171\/jns.1982.56.1.0019","volume":"56","author":"TW Langfitt","year":"1982","unstructured":"Langfitt TW, Gennarelli TA (1982) Can outcome from head injury be improved? J Neurosurg 56:19\u201325","journal-title":"J Neurosurg"},{"key":"BF01708961_CR4","unstructured":"Jennett B, Mendelow AD (1989) Head injuries. In: Nunn JF, Utting JE, Brown Jr BR (eds) General anaesthesia. Butterworth 109, pp 1304\u20131317"},{"key":"BF01708961_CR5","doi-asserted-by":"crossref","first-page":"450","DOI":"10.3171\/jns.1992.76.3.0450","volume":"76","author":"EF Aldrich","year":"1992","unstructured":"Aldrich EF, Eisenberg HM, Saydjari C, Luerssen TG, Foulkes MA, Jane JA, Marshall LF, Marmarou A, Young HF (1992) Diffuse brain swelling in severely head-injured children. A report from the NIH traumatic coma data bank. J Neurosurg 76:450\u2013454","journal-title":"J Neurosurg"},{"key":"BF01708961_CR6","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1093\/bja\/57.1.120","volume":"57","author":"JD Miller","year":"1985","unstructured":"Miller JD (1985) Head injury and brain ischaemia, implications for therapy. Br J Anaesth 57:120\u2013129","journal-title":"Br J Anaesth"},{"key":"BF01708961_CR7","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1097\/00005373-199008000-00001","volume":"30","author":"MJ Rosner","year":"1990","unstructured":"Rosner MJ, Daughton S (1990) Cerebral perfusion pressure management in head injury. J Trauma 30:933\u2013941","journal-title":"J Trauma"},{"key":"BF01708961_CR8","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3171\/sup.1991.75.1s.0s59","volume":"75","author":"A Marmarou","year":"1991","unstructured":"Marmarou A, Andersson RL, Ward JD, Choi SC, Young HF (1991) Impact of ICP instability and hypotension on outcome in patients with severe head trauma. J Neurosurg 75:59\u201366","journal-title":"J Neurosurg"},{"issue":"Suppl 1","key":"BF01708961_CR9","first-page":"317","volume":"9","author":"JD Miller","year":"1992","unstructured":"Miller JD, Dearden MM, Piper IR, Chan KH (1992) Control of intracranial pressure in patients with severe head injury. J Neurotrauma 9 [Suppl 1]:317\u2013326","journal-title":"J Neurotrauma"},{"key":"BF01708961_CR10","doi-asserted-by":"crossref","first-page":"231","DOI":"10.3171\/jns.1986.64.2.0231","volume":"64","author":"K Messeter","year":"1986","unstructured":"Messeter K, Nordstr\u00f6m CH, Sundb\u00e4rg G, Algotsson L, Ryding E (1986) Cerebral hemodynamics in patients with acute severe head trauma. J Neurosurg 64:231\u2013237","journal-title":"J Neurosurg"},{"key":"BF01708961_CR11","doi-asserted-by":"crossref","first-page":"424","DOI":"10.3171\/jns.1988.68.3.0424","volume":"68","author":"CH Nordstr\u00f6m","year":"1988","unstructured":"Nordstr\u00f6m CH, Messeter K, sundb\u00e4rg G, Schalen W, Werner M, Ryding E (1988) Cerebral blood flow, vasoreactivity and oxygen consumption during barbiturate therapy in severe traumatic brain lesions. J Neurosurg 68:424\u2013431","journal-title":"J Neurosurg"},{"key":"BF01708961_CR12","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/j.1399-6576.1991.tb03258.x","volume":"35","author":"W Schalen","year":"1991","unstructured":"Schalen W, Messeter K, Nordstr\u00f6m CH (1991) Cerebral vasoreactivity and the prediction of outcome in severe traumatic brain lesions. Acta Anaesth Scand 35:113\u2013122","journal-title":"Acta Anaesth Scand"},{"key":"BF01708961_CR13","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1097\/00001503-199110000-00005","volume":"4","author":"J Astrup","year":"1991","unstructured":"Astrup J (1991) Drug treatment in head injury. Current Opin Anaesthesiol 4:653\u2013656","journal-title":"Current Opin Anaesthesiol"},{"key":"BF01708961_CR14","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1056\/NEJM199211193272108","volume":"327","author":"RL White","year":"1992","unstructured":"White RL, Likavec MJ (1992) The diagnosis and initial management of head injury. N Engl J Med 327:1507\u20131511","journal-title":"N Engl J Med"},{"key":"BF01708961_CR15","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3171\/jns.1992.77.1.0055","volume":"77","author":"KH Chan","year":"1992","unstructured":"Chan KH, Miller JD, Dearden NM, Andrews PJD, Midgley S (1992) The effect of changes in cerebral perfusion pressure upon middle cerebral artery blood flow velocity and jugular bulb venous oxygen saturation after severe brain injury. J Neurosurg 77:55\u201361","journal-title":"J Neurosurg"},{"key":"BF01708961_CR16","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0022-510X(78)90124-7","volume":"39","author":"DI Graham","year":"1987","unstructured":"Graham DI, Adams JH, Doyle D (1987) Ischemic brain damage in fatal non-missile head injuries. J Neurol Sci 39:213\u2013234","journal-title":"J Neurol Sci"},{"key":"BF01708961_CR17","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/BF01456166","volume":"96","author":"GE Cold","year":"1989","unstructured":"Cold GE (1989) Does acute hyperventilation provoke cerebral oligemia in comatose patients after head injury? Acta Neurochir 96:100\u2013106","journal-title":"Acta Neurochir"},{"key":"BF01708961_CR18","doi-asserted-by":"crossref","first-page":"241","DOI":"10.3171\/jns.1984.61.2.0241","volume":"61","author":"WD Obrist","year":"1984","unstructured":"Obrist WD, Langfitt TW, Jaggi JL, Cruz J, Gennarelli TA (1984) Cerebral flood flow and metabolism in comatose patients with acute head injury. J Neurosurg 61:241\u2013253","journal-title":"J Neurosurg"},{"key":"BF01708961_CR19","doi-asserted-by":"crossref","first-page":"383","DOI":"10.3171\/jns.1985.62.3.0383","volume":"62","author":"JD Ward","year":"1985","unstructured":"Ward JD, Becker DP, Miller JD, Choi SC, Marmarou A, Wood C, Newlon PG, Keenan R (1985) Fallure of prophylactic barbiturate coma in the treatment of severe head injury. J Neurosurg 62: 383\u2013388","journal-title":"J Neurosurg"},{"key":"BF01708961_CR20","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/j.1399-6576.1992.tb03483.x","volume":"36","author":"W Schalen","year":"1992","unstructured":"Schalen W, Messeter K, Nordstr\u00f6m CH (1992) Complications and side-effects during thiopental therapy in patients with severe head injuries. Acta Anaesth Scand 36:369\u2013377","journal-title":"Acta Anaesth Scand"},{"key":"BF01708961_CR21","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/BF01735179","volume":"16","author":"PO Gr\u00e4nde","year":"1990","unstructured":"Gr\u00e4nde PO, Gustafsson D, Lindberg L (1990) Effects of thiopental on resistance vessels in cat skeletal muscle. Intensive Care Med 16:399\u2013404","journal-title":"Intensive Care Med"},{"key":"BF01708961_CR22","first-page":"94","volume":"36","author":"NM Dearden","year":"1986","unstructured":"Dearden NM (1986) Management of raised ICP after severe head injury. Br J Hosp Med 36:94\u2013103","journal-title":"Br J Hosp Med"},{"key":"BF01708961_CR23","doi-asserted-by":"crossref","first-page":"584","DOI":"10.3171\/jns.1992.77.4.0584","volume":"77","author":"AM Kaufmann","year":"1992","unstructured":"Kaufmann AM, Cardoso ER (1992) Aggravation of vasogenic cerebral edema by multiple dose mannitol. J Neurosurg 77:584\u2013589","journal-title":"J Neurosurg"},{"issue":"Suppl 1","key":"BF01708961_CR24","first-page":"15","volume":"8","author":"B Jennet","year":"1991","unstructured":"Jennet B (1991) Diagnosis and management of head trauma. J Neurotrauma 8 [Suppl 1]:15\u201319","journal-title":"J Neurotrauma"},{"key":"BF01708961_CR25","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/978-4-431-68231-8_72","volume-title":"Recent advances in neurotraumatology","author":"PO Gr\u00e4nde","year":"1993","unstructured":"Gr\u00e4nde PO, Asgeirsson B, Nordstr\u00f6m CH (1993) A new potential therapy for treatment of posttraumatic brain oedema based on haemodynamic principles for brain volume regulation. In: Nakamura N, Hashimoto T, Yasue M (eds) Recent advances in neurotraumatology. Springer, Tokyo, pp 319\u2013322"},{"key":"BF01708961_CR26","doi-asserted-by":"crossref","first-page":"386","DOI":"10.3171\/jns.1988.69.3.0386","volume":"69","author":"CJ McClain","year":"1988","unstructured":"McClain CJ, Henning B, Ott LG, Goldblum S, Young AB (1988) Mechanisms and implications of hypoalbuminemia in head-injured patients. J Neurosurg 69:386\u2013392","journal-title":"J Neurosurg"},{"issue":"Suppl","key":"BF01708961_CR27","first-page":"296","volume":"51","author":"NV Todd","year":"1990","unstructured":"Todd NV, Graham DI (1990) Blood-brain barrier damage in traumatic brain contusions. Acta Neurochir [Suppl] 51:296\u2013299","journal-title":"Acta Neurochir"},{"key":"BF01708961_CR28","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/BF00273564","volume":"15","author":"PO Gr\u00e4nde","year":"1989","unstructured":"Gr\u00e4nde PO (1989) The effect of dihydroergotamine in patients with head injury and raised intracranial pressure. Intensive Care Med 15:523\u2013527","journal-title":"Intensive Care Med"},{"key":"BF01708961_CR29","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/BF01708372","volume":"19","author":"B Roth","year":"1993","unstructured":"Roth B, Gr\u00e4nde PO, Nilsson-Ehle P, Eliasson I (1993) Possible role of short-term parenteral nutrition with fat emulsions for development of haemophagocytosis with multiple organ failure in a patient with traumatic brain injury. Intensive Care Med 19:111\u2013114","journal-title":"Intensive Care Med"},{"key":"BF01708961_CR30","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1111\/j.1399-6576.1977.tb01213.x","volume":"21","author":"GE Cold","year":"1977","unstructured":"Cold GE, Taagehoj Jensen F, Malmros R (1977) The cerebrovascular CO2 reactivity during the acute phase of brain injury. Acta Anaesth Scand 21:222\u2013231","journal-title":"Acta Anaesth Scand"},{"key":"BF01708961_CR31","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1227\/00006123-198409000-00023","volume":"15","author":"JH Piatt","year":"1984","unstructured":"Piatt JH, Schiff SJ (1984) High dose barbiturate therapy in neurosurgery and intensive care. Neurosurgery 15:427\u2013444","journal-title":"Neurosurgery"},{"key":"BF01708961_CR32","doi-asserted-by":"crossref","first-page":"723","DOI":"10.3171\/jns.1973.39.6.0723","volume":"39","author":"K Yada","year":"1973","unstructured":"Yada K, Nagakawa Y, Tsuru M (1973) Circulatory disturbance of the venous system during experimental intracranial hypertension. J Neurosurg 39:723\u2013729","journal-title":"J Neurosurg"},{"issue":"2","key":"BF01708961_CR33","first-page":"41","volume":"6","author":"PO Gr\u00e4nde","year":"1992","unstructured":"Gr\u00e4nde PO (1992) New haemodynamic aspects on treatment of posttraumatic brain oedema. Svensk F\u00f6rening f\u00f6r Anestesi och Intensivv\u00e5rd sept, Vol. 6; 2: pp 41\u201346","journal-title":"Svensk F\u00f6rening f\u00f6r Anestesi och Intensivv\u00e5rd sept"},{"key":"BF01708961_CR34","doi-asserted-by":"crossref","first-page":"32c","DOI":"10.1016\/0002-9149(89)90403-7","volume":"63","author":"JM Simard","year":"1989","unstructured":"Simard JM, Bellefleur M (1989) Systemic arterial hypertension in head trauma. Am J Cardiol 63:32c-35c","journal-title":"Am J Cardiol"},{"key":"BF01708961_CR35","doi-asserted-by":"crossref","first-page":"447","DOI":"10.3171\/jns.1983.59.3.0447","volume":"59","author":"GL Clifton","year":"1983","unstructured":"Clifton GL, Robertson CS, Kyper K, Taylor AA, Dhekne RD, Grossman RG (1983) Cardiovascular responses to severe head injury. J Neurosurg 59:447\u2013454","journal-title":"J Neurosurg"},{"key":"BF01708961_CR36","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S0140-6736(87)92984-9","volume":"I","author":"JM Cruickshank","year":"1987","unstructured":"Cruickshank JM, Neil-Dwyer G, Degaute JP, Hayes Y, Kuurne T, Kytta J, Vincent JL, Carruthers ME, Patel S (1987) Reduction of stress\/catecholamine-induced cardiac necrosis by \u03b21-selective blockade. Lancet I:585\u2013589","journal-title":"Lancet"},{"key":"BF01708961_CR37","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1093\/brain\/91.2.281","volume":"91","author":"HS Schutta","year":"1986","unstructured":"Schutta HS, Kassell NF, Langfitt TW (1986) Brain swelling produced by injury and aggravated by arterial hypertension. Brain 91:281\u2013294","journal-title":"Brain"},{"key":"BF01708961_CR38","first-page":"198","volume-title":"Update in intensive care and emergency medicine. Brain failure","author":"K Gunning","year":"1989","unstructured":"Gunning K, Forster A (1989) Cerebral blood flow in head injury. In: Bihari D, Holaday JW (eds) Update in intensive care and emergency medicine. Brain failure. Springer, Berlin Heidelberg New York, 9:198\u2013205"},{"key":"BF01708961_CR39","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/978-1-4613-0701-3_11","volume-title":"Implications of the blood-brain barrier and its manipulation, vol 1","author":"HM Pappius","year":"1989","unstructured":"Pappius HM (1989) Cerebral edema and the blood-brain barrier. In: Neuwelt EA (ed) Implications of the blood-brain barrier and its manipulation, vol 1. Plenum, New York, pp 293\u2013309"},{"key":"BF01708961_CR40","first-page":"48","volume":"110","author":"CJ McClain","year":"1987","unstructured":"McClain CJ, Cohen D, Ott L, Dinarello CA, Young B (1987) Ventricular fluid interleukin-1 activity in patients with head injury. J Lab Clin Med 110:48\u201354","journal-title":"J Lab Clin Med"},{"key":"BF01708961_CR41","series-title":"Fidia Research Series","first-page":"153","volume-title":"Traumatic brain oedema, vol 8","author":"T Doczi","year":"1987","unstructured":"Doczi T, Jojart I, Laszlo FA, Szerdahelyi P, Joo F, Bodosi M (1987) Significance of central vasopressin in the regulation of the water and ion balance in the central nervous system. In: Cohadon F, Baethmann A, Go KG, Miller JD (eds) Traumatic brain oedema, vol 8. Fidia Research Series, Liviana Press, Padova, pp 153\u2013160"},{"key":"BF01708961_CR42","doi-asserted-by":"crossref","first-page":"292","DOI":"10.3171\/jns.1979.51.3.0292","volume":"51","author":"W Obrist","year":"1979","unstructured":"Obrist W, Gennarelli TA, Segawa H, Dolinskas C, Langfitt TW (1979) Relation of cerebral blood flow to neutrological status and outcome in head-injured patients. J Neurosurg 51:292\u2013300","journal-title":"J Neurosurg"},{"issue":"Suppl 1","key":"BF01708961_CR43","first-page":"333","volume":"9","author":"GJ Bouma","year":"1992","unstructured":"Bouma GJ, Muizelaar JP (1992) Cerebral blood flow, cerebral blood volume, and cerebrovascular reactivity after severe head injury. J Neurotrauma 9 [Suppl 1]:333\u2013348","journal-title":"J Neurotrauma"},{"key":"BF01708961_CR44","doi-asserted-by":"crossref","first-page":"170","DOI":"10.3171\/jns.1981.54.2.0170","volume":"54","author":"DA Bruce","year":"1981","unstructured":"Bruce DA, Alavi A, Bilaniuk L, Dolinskas C, Obrist W, Uzzell B (1981) Diffuse cerebral swelling following head injuries in children: the syndrome of malignant brain oedema. J Neurosurg 54:170\u2013178","journal-title":"J Neurosurg"}],"container-title":["Intensive Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01708961.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01708961\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01708961","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,8]],"date-time":"2019-05-08T12:42:21Z","timestamp":1557319341000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01708961"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,4]]},"references-count":44,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1994,4]]}},"alternative-id":["BF01708961"],"URL":"https:\/\/doi.org\/10.1007\/bf01708961","relation":{},"ISSN":["0342-4642","1432-1238"],"issn-type":[{"value":"0342-4642","type":"print"},{"value":"1432-1238","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,4]]}}}