{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T15:10:08Z","timestamp":1683126608469},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1992,2,1]],"date-time":"1992-02-01T00:00:00Z","timestamp":696902400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Hematol"],"published-print":{"date-parts":[[1992,2]]},"DOI":"10.1007\/bf01715348","type":"journal-article","created":{"date-parts":[[2005,6,28]],"date-time":"2005-06-28T00:30:51Z","timestamp":1119918651000},"page":"72-77","source":"Crossref","is-referenced-by-count":2,"title":["Presence of more than two rearranged immunoglobulin heavy-chain genes in adult precursor B-cell acute lymphoblastic leukemia"],"prefix":"10.1007","volume":"64","author":[{"given":"C.","family":"Schardt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Hoelzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ganser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF01715348_CR1","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/0092-8674(81)90421-9","volume":"27","author":"F Alt","year":"1981","unstructured":"Alt F, Rosenberg N, Lewis S, Thomas E, Baltimore D (1981) Organisation and reorganisation of immunoglobulin genes in A-MuLV-transformed cells: rearrangement of heavy but not light chain genes. Cell 27: 381\u2013390","journal-title":"Cell"},{"key":"BF01715348_CR2","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1056\/NEJM198312293092601","volume":"309","author":"A Arnold","year":"1983","unstructured":"Arnold A, Cossmann J, Bakshi A, Jaffe ES, Waldmann TA, Korsmeyer SJ (1983) Immunoglobulin gene rearrangements as unique clonal markers in human lymphoid neoplasms. N Engl J Med 309: 1593\u20131599","journal-title":"N Engl J Med"},{"key":"BF01715348_CR3","first-page":"165","volume":"7","author":"DC Arthur","year":"1982","unstructured":"Arthur DC, Bloomfield CD, Linquist LL, Nesbit ME jr (1982) Translocation (4; 11) in acute lymphoblastic leukemia: clinical characteristics and prognostic significance. Blood 7: 165\u2013172","journal-title":"Blood"},{"key":"BF01715348_CR4","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1056\/NEJM198310063091404","volume":"309","author":"A Bakshi","year":"1983","unstructured":"Bakshi A, Minowada J, Arnold A, Cosman J, Jensen JP, Whang-Peng J, Waldmann T, Korsmeyer SJ (1983) Lymphoid blast crises of chronic myelogenous leukemia represent stages in the development of B-cell precursors. N Engl J Med 309: 826\u2013830","journal-title":"N Engl J Med"},{"key":"BF01715348_CR5","first-page":"657","volume":"5","author":"A Beishuizen","year":"1991","unstructured":"Beishuizen A, H\u00e4hlen K, Hagemeijer A, Verhoeven MAJ, Hooijkaas H, Adriaansen HJ, Wolvers-Tettero ILM, van Wering ER, van Dongen JJM (1991) Multiple rearranged immunoglobulin genes in childhood acute lymphoblastic leukemia of precursor B-cell origin. Leukemia 5: 657\u2013667","journal-title":"Leukemia"},{"key":"BF01715348_CR6","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1084\/jem.168.1.229","volume":"168","author":"J Bird","year":"1988","unstructured":"Bird J, Galili N, Link M, Stites D, Sklar J (1988) Continuing rearrangement but absence of somatic hypermutation in immunoglobulin genes of human B-cell precursor leukemia. J Exp Med 168: 229\u2013245","journal-title":"J Exp Med"},{"key":"BF01715348_CR7","doi-asserted-by":"crossref","first-page":"2303","DOI":"10.1093\/nar\/3.9.2303","volume":"3","author":"N Blin","year":"1975","unstructured":"Blin N, Stafford DW (1975) Isolation of high-molecular-weight DNA. Nucleic Acids Res 3: 2303\u20132308","journal-title":"Nucleic Acids Res"},{"key":"BF01715348_CR8","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0092-8674(86)90488-5","volume":"44","author":"ML Cleary","year":"1986","unstructured":"Cleary ML, Meeker TC, Levy E, Lee M, Trela M, Sklar J, Levy R (1986) Clustering of extensive somatic mutations in the variable region of an immunoglobulin heavy chain gene from a human B-cell lymphoma. Cell 44: 97\u2013109","journal-title":"Cell"},{"key":"BF01715348_CR9","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/0092-8674(80)90089-6","volume":"19","author":"P Early","year":"1980","unstructured":"Early P, Huang H, Davis M, Calame K, Hood L (1980) An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: Vh, D and Jh. Cell 19: 981\u2013992","journal-title":"Cell"},{"key":"BF01715348_CR10","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1200\/JCO.1990.8.3.431","volume":"8","author":"CA Felix","year":"1990","unstructured":"Felix CA, Poplack DG, Reaman GH, Steinberg SM, Cole DE, Taylor BJ, Begley CG, Kirsch IR (1990) Characterisation of immunoglobulin and T-cell receptor gene patterns in B-cell precursor acute lymphoblastic leukemia of childhood. J Clin Oncol 8: 431\u2013442","journal-title":"J Clin Oncol"},{"key":"BF01715348_CR11","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1172\/JCI111594","volume":"74","author":"R Foa","year":"1984","unstructured":"Foa R, Migone N, Saitta M, Fiero MT, Giubellino MC, Lusso P, Cordero di Montezemolo L, Miniero R, Lauria F (1984) Different stages of B-cell differentiation in non-T acute lymphoblastic leukemia. J Clin Invest 74: 1756\u20131763","journal-title":"J Clin Invest"},{"key":"BF01715348_CR12","first-page":"1","volume":"68","author":"KA Foon","year":"1986","unstructured":"Foon KA, Todd III RF (1986) Immunologic classification of leukemia and lymphoma. Blood 68: 1\u201331","journal-title":"Blood"},{"key":"BF01715348_CR13","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1126\/science.3535067","volume":"234","author":"MF Greaves","year":"1986","unstructured":"Greaves MF (1986) Differentiation-linked leukemogenesis in lymphocytes. Science 234: 697\u2013704","journal-title":"Science"},{"key":"BF01715348_CR14","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1172\/JCI111310","volume":"70","author":"K Ha","year":"1984","unstructured":"Ha K, Minden M, Hozumi N, Gelfand EW (1984) Immunoglobulin \u03bc-chain gene rearrangement in a patient with T-cell acute lymphoblastic leukemia. J Clin Invest 70: 1232\u20131236","journal-title":"J Clin Invest"},{"key":"BF01715348_CR15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0145-2126(86)90098-6","volume":"10","author":"K Ha","year":"1986","unstructured":"Ha K, Minden M, Hozumi N, Gelfand EW (1986) Single allelic C\u03bc gene rearrangements in patients with T-cell and undifferentiated leukemia. Leuk Res 10: 1\u20138","journal-title":"Leuk Res"},{"key":"BF01715348_CR16","first-page":"24","volume":"1","author":"A Hagemeijer","year":"1987","unstructured":"Hagemeijer A, van Dongen JJM, Slater RM, van't Veer MB, Behrendt H, H\u00e4hlen K, Sizzo W, Abels J (1987) Characterization of the blast cells in acute leukemia with translocation (4; 11): report of eight additional cases and of one case with a variant translocation. Leukemia 1: 24\u201331","journal-title":"Leukemia"},{"key":"BF01715348_CR17","volume-title":"ISCN: An International System of Human cytogenetic nomenclature","year":"1985","unstructured":"Hardnen DG, Klinger HP (eds) (1985) ISCN: An International System of Human cytogenetic nomenclature. Karger, Basel"},{"key":"BF01715348_CR18","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1182\/blood.V71.1.123.123","volume":"71","author":"D Hoelzer","year":"1988","unstructured":"Hoelzer D, Thiel E, Loeffler H, B\u00fcchner T, Ganser A, Heil G, Koch P, Freund M, Diedrich H, R\u00fchl H, Marschmeyer G, Lipp T, Nowrousian MR, Burkert M, Gerecke D, Pralle H, M\u00fcller U, Lunscken Ch, F\u00fclle H, Ho AD, K\u00fcchler R, Busch FW, Schneider W, G\u00f6rg CH, Emmerich B, Braumann D, Vaupel HA, von Paleske A, Bartels H, Neiss A, Messerer D (1988) Prognostic factors in a multicenter study for treatment of acute lymphoblastic leukemia in adults. Blood 71: 123\u2013131","journal-title":"Blood"},{"key":"BF01715348_CR19","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1146\/annurev.bi.54.070185.004103","volume":"54","author":"T Honjo","year":"1985","unstructured":"Honjo T, Habu S (1985) Origin of immune diversity: genetic variation and selection. Ann Rev Biochem 54: 803\u2013830","journal-title":"Ann Rev Biochem"},{"key":"BF01715348_CR20","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1182\/blood.V71.5.1438.1438","volume":"71","author":"F Katz","year":"1988","unstructured":"Katz F, Malcolm S, Gibbons B, Tilly R, Lam G, Robertson ME, Czepulkowski B, Chessel J (1988) Cellular and molecular studies on infant null acute lymphoblastic leukemia. Blood 71: 1438\u20131447","journal-title":"Blood"},{"key":"BF01715348_CR21","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/j.1365-2141.1989.tb00249.x","volume":"73","author":"F Katz","year":"1989","unstructured":"Katz F, Ball L, Gibbons B, Chessel J (1989) The use of DNA probes to monitor minimal residual disease in childhood acute lymphoblastic leukemia. Br J Haematol 73: 173\u2013180","journal-title":"Br J Haematol"},{"key":"BF01715348_CR22","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1182\/blood.V65.3.725.725","volume":"65","author":"GR Kitchingman","year":"1985","unstructured":"Kitchingman GR, Rovigatti U, Mauer AM, Melvin S, Murphy SB, Stass S (1985) Rearrangement of immunoglobulin heavy chain genes in T-cell acute lymphoblastic leukemia. Blood 65: 725\u2013729","journal-title":"Blood"},{"key":"BF01715348_CR23","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1182\/blood.V67.3.698.698","volume":"67","author":"GR Kitchingman","year":"1986","unstructured":"Kitchingman GR, Mirro J, Stass S, Rovigatti U, Melvin SL, Williams DL, Raimondi SC, Murphy SB (1986) Biologic and prognostic significance of the presence of more than two \u03bc heavy-chain genes in childhood acute lymphoblastic leukemia of B-precursor cell origin. Blood 67: 698\u2013703","journal-title":"Blood"},{"key":"BF01715348_CR24","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1172\/JCI110770","volume":"71","author":"SJ Korsmeyer","year":"1983","unstructured":"Korsmeyer SJ, Arnold A, Bakshi A, Ravetch JV, Siebenlist U, Hieter PH, Sharrow SO, Le Bien TW, Kersey JH, Poplack DG, Leder P, Waldmann TA (1983) Immunoglobulin gene rearrangement and cell surface expression in acute lymphoblastic leukemia of T-cell and B-cell precursor origins. J Clin Invest 71: 301\u2013313","journal-title":"J Clin Invest"},{"key":"BF01715348_CR25","doi-asserted-by":"crossref","first-page":"63","DOI":"10.3109\/00313028409067912","volume":"16","author":"MD Levin","year":"1984","unstructured":"Levin MD, Michael PM, Garson OM, Tiedemann K, Firkin FC (1984) Clinicopathological characteristics of acute lymphoblastic leukemia with the (4; 11) translocation. Pathology 16: 63\u201366","journal-title":"Pathology"},{"key":"BF01715348_CR26","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1182\/blood.V67.3.689.689","volume":"67","author":"J Mirro","year":"1986","unstructured":"Mirro J, Kitchingman G, Williams D, Lauzon GJ, Lin C-C, Callihan T, Zipf TF (1986) Clinical and laboratory characteristics of acute leukemia with the (4; 11) translocation. Blood 67: 689\u2013697","journal-title":"Blood"},{"key":"BF01715348_CR27","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1182\/blood.V77.3.440.440","volume":"77","author":"CH Pui","year":"1991","unstructured":"Pui CH, Frankel LS, Carroll AJ, Raimondi SC, Shuster JJ, Head DR, Crist WM, Land WJ, Pullen DJ, Steuber CP, Behm FG, Borowitz MJ (1991) Clinical characteristics and treatment outcome of childhood acute lymphoblastic leukemia with the t (4; 11) (q21; q23): a collaborative study of 40 cases. Blood 77: 440\u2013447","journal-title":"Blood"},{"key":"BF01715348_CR28","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1182\/blood.V68.3.658.658","volume":"68","author":"A Raghvachar","year":"1986","unstructured":"Raghvachar A, Bartram C, Ganser A, Heil G, Kleihauer E, Kubanek B (1986) Acute undifferentiated leukemia: implications of cellular origin and clonality suggested by analysis of surface markers and immunoglobulin gene rearrangement. Blood 68: 658\u2013662","journal-title":"Blood"},{"key":"BF01715348_CR29","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/0092-8674(81)90400-1","volume":"27","author":"JV Ravetch","year":"1981","unstructured":"Ravetch JV, Siebenlist U, Korsmeyer S, Waldmann T, Leder P (1981) The structure of the human immunoglobulin \u03bc locus: characterization of embryonic and rearranged J and D genes. Cell 27: 583\u2013591","journal-title":"Cell"},{"key":"BF01715348_CR30","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1084\/jem.161.4.850","volume":"161","author":"MH Siegelman","year":"1985","unstructured":"Siegelman MH, Cleary ML, Warnke R, Sklar J (1985) Frequent biclonality and Ig gene alterations among B-cell lymphomas that show multiple histologic forms. J Exp Med 161: 850\u2013863","journal-title":"J Exp Med"},{"key":"BF01715348_CR31","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1056\/NEJM198407053110104","volume":"311","author":"J Sklar","year":"1984","unstructured":"Sklar J, Cleary ML, Thielemanns K, Gralow J, Warnke R, Levy R (1984) Biclonal B-cell lymphoma. N Engl J Med 311: 21\u201327","journal-title":"N Engl J Med"},{"key":"BF01715348_CR32","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1038\/304172a0","volume":"304","author":"RA Taub","year":"1983","unstructured":"Taub RA, Hollis RF, Hieter PA, Korsmeyer S, Waldmann TA, Leder P (1983) Variable amplification of immunoglobulin \u03bb light-chain genes in human populations. Nature 304: 172\u2013175","journal-title":"Nature"},{"key":"BF01715348_CR33","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1038\/302575a0","volume":"302","author":"S Tonegawa","year":"1983","unstructured":"Tonegawa S (1983) Somatic generation of antibody diversity. Nature 302: 575\u2013581","journal-title":"Nature"},{"key":"BF01715348_CR34","doi-asserted-by":"crossref","first-page":"3144","DOI":"10.4049\/jimmunol.135.5.3144","volume":"135","author":"JJM Dongen Van","year":"1985","unstructured":"Van Dongen JJM, Hooijkaas H, Comans-Bitter M, H\u00e4hlen K, de Klein A, van Zanen GE, van't Veer MB, Abels J, Benner R (1985) Human bone marrow cells positive for terminal deoxynucleotidyl transferase (TdT), HLA-DR, and a T-cell marker may represent prothymocytes. J Immunol 135: 3144\u20133150","journal-title":"J Immunol"},{"key":"BF01715348_CR35","first-page":"298","volume":"33","author":"JJM Dongen Van","year":"1988","unstructured":"Van Dongen JJM, Adriaansen HJ, Hooijkaas H (1988) Immunophenotyping of leukemias and non-Hodgkin lymphomas: immunological markers and their CD codes. Neth J Med 33: 298\u2013314","journal-title":"Neth J Med"},{"key":"BF01715348_CR36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0009-8981(91)90246-9","volume":"198","author":"JJM Dongen Van","year":"1991","unstructured":"Van Dongen JJM, Wolvers-Tettero ILM (1991) Analysis of immunoglobulin and T-cell receptor genes. I. Basic and technical aspects. Clin Chim Acta 198: 1\u201391","journal-title":"Clin Chim Acta"},{"key":"BF01715348_CR37","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0009-8981(91)90247-A","volume":"198","author":"JJM Dongen Van","year":"1991","unstructured":"Van Dongen JJM, Wolvers-Tettero ILM (1991) Analysis of immunoglobulin and T-cell receptor genes. II. Possibilities and limitations in the diagnosis and management of lymphoproliferative diseases and related disorders. Clin Chim Acta 198: 93\u2013174","journal-title":"Clin Chim Acta"},{"key":"BF01715348_CR38","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/BF00320838","volume":"47","author":"J-U Walther","year":"1983","unstructured":"Walther J-U, Wirtz A, Thiel E, Bender-G\u00f6tze CH (1983) Specific translocation t (4; 11) in an infant with acute lymphoblastic leukemia of null cell type. Blut 47: 195\u2013202","journal-title":"Blut"},{"key":"BF01715348_CR39","doi-asserted-by":"crossref","first-page":"3430","DOI":"10.1073\/pnas.82.10.3430","volume":"82","author":"Y Yanagi","year":"1985","unstructured":"Yanagi Y, Chan A, Chin B, Minden M, Mak TW (1985) Analyses of cDNA clones specific for human T cells and the \u03b1 and \u03b2 chains of the T-cell receptor heterodimer from a human T-cell line. Proc Natl Acad Sci USA 82: 3430\u20133434","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["Annals of Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01715348.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01715348\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01715348","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T14:35:12Z","timestamp":1683124512000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01715348"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,2]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1992,2]]}},"alternative-id":["BF01715348"],"URL":"https:\/\/doi.org\/10.1007\/bf01715348","relation":{},"ISSN":["0939-5555","1432-0584"],"issn-type":[{"value":"0939-5555","type":"print"},{"value":"1432-0584","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,2]]}}}