{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T08:49:47Z","timestamp":1791103787369,"version":"4.1.0"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1991,1,1]],"date-time":"1991-01-01T00:00:00Z","timestamp":662688000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anat Embryol"],"published-print":{"date-parts":[[1991,1]]},"DOI":"10.1007\/bf01744263","type":"journal-article","created":{"date-parts":[[2005,6,17]],"date-time":"2005-06-17T08:59:16Z","timestamp":1118998756000},"page":"71-82","source":"Crossref","is-referenced-by-count":41,"title":["Microglia in tadpoles ofXenopus laevis: Normal distribution and the response to optic nerve injury"],"prefix":"10.1007","volume":"184","author":[{"given":"I. A.","family":"Goodbrand","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. M.","family":"Gaze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF01744263_CR1","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1097\/00005072-198109000-00005","volume":"40","author":"A Bignami","year":"1981","unstructured":"Bignami A, Dahl D, Nguyen BT, Crosby CJ (1981) The fate of axonal debris in Wallerian degeneration of rat optic and sciatic nerves. J Neuropath Exp Neurol 40:537\u2013550","journal-title":"J Neuropath Exp Neurol"},{"key":"BF01744263_CR2","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1083\/jcb.106.4.1281","volume":"106","author":"P Caroni","year":"1988","unstructured":"Caroni P, Schwab ME (1988) Two membrane protein fractions from rat central myelin with inhibitory properties for neurite growth and fibroblast spreading. J Cell Biol 106:1281\u20131288","journal-title":"J Cell Biol"},{"key":"BF01744263_CR3","doi-asserted-by":"crossref","first-page":"4042","DOI":"10.1523\/JNEUROSCI.09-11-04042.1989","volume":"9","author":"DA Carter","year":"1989","unstructured":"Carter DA, Bray GM, Aguayo AJ (1989) Regenerated retinal ganglion cell axons can form well-differentiated synapses in the superior colliculus of adult hamsters. J Neurosci 9:4042\u20134050","journal-title":"J Neurosci"},{"key":"BF01744263_CR4","first-page":"389","volume-title":"Molecular bases of neural development","author":"WM Cowan","year":"1985","unstructured":"Cowan WM, Hunt RK (1985) The development of the retinotectal projection: an overview. In: Edelman GM, Gall WE, Cowan WM (eds) Molecular bases of neural development. Wiley, New York, pp 389\u2013428"},{"key":"BF01744263_CR5","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1523\/JNEUROSCI.04-04-01052.1984","volume":"4","author":"SS Easter Jr","year":"1984","unstructured":"Easter SS Jr, Stuermer CAO (1984) An evaluation of the hypothesis of shifting terminals in goldfish optic tectum. J Neurosci 4:1052\u20131063","journal-title":"J Neurosci"},{"key":"BF01744263_CR6","first-page":"201","volume":"44","author":"RM Gaze","year":"1978","unstructured":"Gaze RM, Grant P (1978) The diencephalic course of regenerating retinotectal fibres inXenopus tadpoles. J Embryol Exp Morphol 44:201\u2013216","journal-title":"J Embryol Exp Morphol"},{"key":"BF01744263_CR7","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1098\/rspb.1974.0021","volume":"185","author":"RM Gaze","year":"1974","unstructured":"Gaze RM, Keating MJ, Chung SH (1974) The evolution of the retinotectal map during development inXenopus. Proc R Soc Lond [Biol] 185:301\u2013330","journal-title":"Proc R Soc Lond [Biol]"},{"key":"BF01744263_CR8","first-page":"181","volume":"182","author":"RM Gaze","year":"1990","unstructured":"Gaze RM, Wilson MA, Taylor JSH (1990) Regeneration of optic fibres through the chiasma inXenopus laevis tadpoles. Anat Embryol 182:181\u2013194","journal-title":"Anat Embryol"},{"key":"BF01744263_CR9","unstructured":"Goodbrand IA (1991) The microglial response to optic nerve injury inXenopus. J Physiol (Lond) 434:56p"},{"key":"BF01744263_CR10","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1242\/jcs.1986.Supplement_4.16","volume":"Suppl 4","author":"S Gordon","year":"1986","unstructured":"Gordon S (1986) Biology of the Macrophage. J Cell Sci [Suppl 4]:267\u2013286","journal-title":"J Cell Sci"},{"key":"BF01744263_CR11","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1083\/jcb.97.1.253","volume":"97","author":"DA Hume","year":"1983","unstructured":"Hume DA, Perry VH, Gordon S (1983) Immunohistochemical localization of a macrophage-specific antigen in developing mouse retina: phagocytosis of dying axons and differentiation of microglial cells to form a regular array in the plexiform layers. J Cell Biol 97:253\u2013257","journal-title":"J Cell Biol"},{"key":"BF01744263_CR12","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0165-3806(83)90201-8","volume":"11","author":"GM Innocenti","year":"1983","unstructured":"Innocenti GM, Clarke S, Koppel H (1983) Transitory macrophages in the white matter of the developing visual cortex. II. Development and relations with axonal pathways. Dev Brain Res 11:55\u201366","journal-title":"Dev Brain Res"},{"key":"BF01744263_CR13","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/BF00318336","volume":"174","author":"S Jenkins","year":"1986","unstructured":"Jenkins S, Straznicky C (1986) Naturally occurring and induced ganglion cell death: a retinal whole-mount autoradiographic study inXenopus. Anat Embryol 174:59\u201366","journal-title":"Anat Embryol"},{"key":"BF01744263_CR14","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1126\/science.2799387","volume":"246","author":"SA Kierstead","year":"1989","unstructured":"Kierstead SA, Rasminski M, Fukuda Y, Carter DA, Aguayo AJ, Vidal-Sanz M (1989) Electrophysiologic responses in Hamster superior colliculus evoked by regenerating retinal axons. Science 246:255\u2013257","journal-title":"Science"},{"key":"BF01744263_CR15","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/256495a0","volume":"256","author":"G Kohler","year":"1975","unstructured":"Kohler G, Milstein C (1975) Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256:495\u2013497","journal-title":"Nature"},{"key":"BF01744263_CR16","first-page":"245","volume":"30","author":"G L\u00e1z\u00e1r","year":"1979","unstructured":"L\u00e1z\u00e1r G (1979) Elimination of cobalt from the frog brain introduced into the optic centres through the optic nerve. Acta Biol Acad Sci Hung 30:245\u2013255","journal-title":"Acta Biol Acad Sci Hung"},{"key":"BF01744263_CR17","volume-title":"Normal Table ofXenopus laevis (Daudin)","author":"PD Nieuwkoop","year":"1967","unstructured":"Nieuwkoop PD, Faber J (1967) Normal Table ofXenopus laevis (Daudin). North Holland, Amsterdam"},{"key":"BF01744263_CR18","first-page":"119","volume-title":"Neuroimmune networks: physiology and diseases","author":"VH Perry","year":"1989","unstructured":"Perry VH, Gordon S (1989) Resident macrophages of the central nervous system: modulation of phenotype in relation to a specialized microenvironment. In: Goetzl EJ (ed) Neuroimmune networks: physiology and diseases. Liss, New York, pp 119\u2013125"},{"key":"BF01744263_CR19","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0074-7696(08)61220-6","volume":"125","author":"VH Perry","year":"1991","unstructured":"Perry VH, Gordon S (1991) Macrophages and the nervous system. Int Rev Cytol 125:203\u2013244","journal-title":"Int Rev Cytol"},{"key":"BF01744263_CR20","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/0306-4522(85)90215-5","volume":"15","author":"VH Perry","year":"1985","unstructured":"Perry VH, Hume DA, Gordon S (1985) Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain. Neuroscience 15:313\u2013326","journal-title":"Neuroscience"},{"key":"BF01744263_CR21","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1084\/jem.165.4.1218","volume":"165","author":"VH Perry","year":"1987","unstructured":"Perry VH, Brown MC, Gordon S (1987) The macrophage response to central and peripheral nerve injury. J Exp Med 165:1218\u20131223","journal-title":"J Exp Med"},{"key":"BF01744263_CR22","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/BF01187134","volume":"20","author":"LL Phillips","year":"1991","unstructured":"Phillips LL, Turner JE (1991) Biphasic cellular response to transection in the newt optic nerve: glial reactivity precedes axonal degeneration. J Neurocytol 20:51\u201364","journal-title":"J Neurocytol"},{"key":"BF01744263_CR23","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/0306-4522(89)90409-0","volume":"33","author":"DV Pow","year":"1989","unstructured":"Pow DV, Perry VH, Morris JF, Gordon S (1989) Microglia in the neurohypophysis associate with and endocytose terminal portions of neurosecretory neurons. Neuroscience 33:567\u2013578","journal-title":"Neuroscience"},{"key":"BF01744263_CR24","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1523\/JNEUROSCI.04-02-00442.1984","volume":"4","author":"TA Reh","year":"1984","unstructured":"Reh TA, Constantine-Paton M (1984) Retinal ganglion cell terminals change their projection sites during larval development ofRana pipiens. J Neurosci 4:442\u2013457","journal-title":"J Neurosci"},{"key":"BF01744263_CR25","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1007\/BF01097626","volume":"3","author":"PJ Reier","year":"1974","unstructured":"Reier PJ, Webster H deF (1974) Regeneration and remyelination ofXenopus tadpole optic nerve fibres following transection or crush. J Neurocytol 3:591\u2013618","journal-title":"J Neurocytol"},{"key":"BF01744263_CR26","first-page":"483","volume-title":"Cytology and cellular pathology of the nervous system","author":"P Rio-Hortega del","year":"1932","unstructured":"del Rio-Hortega P (1932) Microglia. In: Penfield W (ed) Cytology and cellular pathology of the nervous system. Hoeber, New York, pp 483\u2013534"},{"key":"BF01744263_CR27","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0166-2236(82)90069-8","volume":"5","author":"JT Schmidt","year":"1982","unstructured":"Schmidt JT (1982) The formation of retinotectal projections. Trends Neurosci 5:111\u2013116","journal-title":"Trends Neurosci"},{"key":"BF01744263_CR28","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1038\/343269a0","volume":"343","author":"L Schnell","year":"1990","unstructured":"Schnell L, Schwab ME (1990) Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors. Nature 343:269\u2013272","journal-title":"Nature"},{"key":"BF01744263_CR29","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1038\/276269a0","volume":"276","author":"M Schulman","year":"1978","unstructured":"Schulman M, Wilde CD, Kohler G (1978) A better cell line for making hybridomas and creating specific antibodies. Nature 276:269\u2013270","journal-title":"Nature"},{"key":"BF01744263_CR30","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/cne.902820207","volume":"282","author":"J Schnitzer","year":"1989","unstructured":"Schnitzer J (1989) Enzyme-histochemical demonstration of microglial cells in the adult and postnatal rabbit retina. J Comp Neurol 282:249\u2013263","journal-title":"J Comp Neurol"},{"key":"BF01744263_CR31","doi-asserted-by":"crossref","first-page":"2381","DOI":"10.1523\/JNEUROSCI.08-07-02381.1988","volume":"8","author":"ME Schwab","year":"1988","unstructured":"Schwab ME, Caroni P (1988) Oligodendrocytes and CNS myelin are nonpermissive substrates for neurite growth and fibroblast spreading in vitro. J Neurosci 8:2381\u20132393","journal-title":"J Neurosci"},{"key":"BF01744263_CR32","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1002\/cne.902820109","volume":"282","author":"AD Springer","year":"1989","unstructured":"Springer AD, Wilson BR (1989) Light microscopic study of degnerating cobalt-filled optic axons in goldfish: role of microglia and radial glia in debris removal. J Comp Neurol 282:119\u2013132","journal-title":"J Comp Neurol"},{"key":"BF01744263_CR33","doi-asserted-by":"crossref","first-page":"2327","DOI":"10.1523\/JNEUROSCI.09-07-02327.1989","volume":"9","author":"G Stoll","year":"1989","unstructured":"Stoll G, Trapp BD, Griffin JW (1989) Macrophage function during Wallerian degeneration of rat optic nerve: clearance of degenerating myelin and 1a expression. J Neurosci 9:2327\u20132335","journal-title":"J Neurosci"},{"key":"BF01744263_CR34","first-page":"87","volume":"28","author":"K Straznicky","year":"1972","unstructured":"Straznicky K, Gaze RM (1972) The development of the tectum inXenopus laevis: an autoradiographic study. J Embryol Exp Morphol 28:87\u2013115","journal-title":"J Embryol Exp Morphol"},{"key":"BF01744263_CR35","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/BF01795308","volume":"16","author":"WJ Streit","year":"1987","unstructured":"Streit WJ, Kreutzberg GW (1987) Lectin binding by resting and reactive microglia. J Neurocytol 16:249\u2013260","journal-title":"J Neurocytol"},{"key":"BF01744263_CR36","first-page":"393","volume":"181","author":"JSH Taylor","year":"1990","unstructured":"Taylor JSH, Gaze RM (1990) The induction of an anomalous ipsilateral retinotectal projection ofXenopus laevis. Anat Embryol 181:393\u2013404","journal-title":"Anat Embryol"},{"key":"BF01744263_CR37","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1002\/ar.1091870303","volume":"187","author":"JE Turner","year":"1977","unstructured":"Turner JE, Glaze KA (1977) The early stages of Wallerian degeneration in the severed optic nerve of the newt (Triturus viridescens). Anat Rec 187:291\u2013310","journal-title":"Anat Rec"},{"key":"BF01744263_CR38","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/ar.1091810208","volume":"181","author":"JE Turner","year":"1975","unstructured":"Turner JE, Singer M (1975) The ultrastructure of Wallerian degeneration in the severed optic nerve of the Newt (Triturus viridescens). Anat Rec 181:267\u2013286","journal-title":"Anat Rec"},{"key":"BF01744263_CR39","doi-asserted-by":"crossref","first-page":"2894","DOI":"10.1523\/JNEUROSCI.07-09-02894.1987","volume":"7","author":"M Vidal-Sanz","year":"1987","unstructured":"Vidal-Sanz M, Bray GM, Villegas-Perez MP, Thanos S, Aguayo AJ (1987) Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat. J Neurosci 7:2894\u20132909","journal-title":"J Neurosci"},{"key":"BF01744263_CR40","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1242\/dev.102.3.537","volume":"102","author":"MA Wilson","year":"1988","unstructured":"Wilson MA, Taylor JSH, Gaze RM (1988) A developmental and ultrastructural study on the optic chiasma inXenopus. Development 102:537\u2013553","journal-title":"Development"}],"container-title":["Anatomy and Embryology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01744263.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01744263\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01744263","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,11]],"date-time":"2021-07-11T23:28:44Z","timestamp":1626046124000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01744263"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,1]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1991,1]]}},"alternative-id":["BF01744263"],"URL":"https:\/\/doi.org\/10.1007\/bf01744263","relation":{},"ISSN":["0340-2061","1432-0568"],"issn-type":[{"value":"0340-2061","type":"print"},{"value":"1432-0568","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,1]]}}}