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High activity was also measured in other lysosomal storage diseases including Krabbe disease, Wolman disease, GM<jats:sub>1<\/jats:sub>\u2010gangliosidosis and to a lesser extent Niemann\u2010Pick disease type B, but the activities were lower than the lowest values in Gaucher patients.<\/jats:p><jats:p>Kinetic properties of the high activity in Gaucher plasma were similar to those of controls. It is not known whether the increased activity represents intrinsic enzyme activity or increased enzyme concentration. It is possible that this enzyme may help in the detection of Gaucher disease or in the assessment of enzyme therapy with<jats:italic>\u03b2<\/jats:italic>\u2010<jats:sc>d<\/jats:sc>\u2010glucosidase (Ceredase\u00ae).<\/jats:p>","DOI":"10.1007\/bf01799265","type":"journal-article","created":{"date-parts":[[2005,6,21]],"date-time":"2005-06-21T16:33:12Z","timestamp":1119371592000},"page":"344-350","source":"Crossref","is-referenced-by-count":13,"title":["Marked increase of methylumbelliferyl\u2010tetra\u2010<i>N<\/i>\u2010acetylchitotetraoside hydrolase activity in plasma from gaucher disease patients"],"prefix":"10.1002","volume":"19","author":[{"given":"W. 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