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Prenatal diagnosis for this disorder may be carried out by galactose\u20101\u2010phosphate uridyl transferase assay in cultured amniotic fluid cells or in chorionic villus biopsies and by galactitol estimation in amniotic fluid supernatant. Although the long\u2010term outcome of patients treated on a galactose\u2010restricted diet is recognized to be unsatisfactory, prenatal diagnosis is only rarely performed with a view to terminating the affected pregnancy.<\/jats:p>","DOI":"10.1007\/bf01799295","type":"journal-article","created":{"date-parts":[[2005,6,21]],"date-time":"2005-06-21T17:33:36Z","timestamp":1119375216000},"page":"202-206","source":"Crossref","is-referenced-by-count":15,"title":["Prenatal diagnosis of disorders of galactose metabolism"],"prefix":"10.1002","volume":"12","author":[{"given":"J. B.","family":"Holton","sequence":"first","affiliation":[{"name":"Department of Clinical Chemistry Southmead Hospital  Bristol BS10 5NB UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. T.","family":"Allen","sequence":"additional","affiliation":[{"name":"Department of Clinical Chemistry Southmead Hospital  Bristol BS10 5NB UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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