{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T05:08:53Z","timestamp":1717477733835},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[1995,3,10]],"date-time":"1995-03-10T00:00:00Z","timestamp":794793600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Inher Metab Disea"],"published-print":{"date-parts":[[1996,9]]},"abstract":"Summary<\/jats:title>Venovenous haemofiltration (VVHF) and haemodiafiltration (VVHDF) were performed with a neonatal haemo(dia)filter (Miniflow 10, Hospal) on 8 anaesthetized rabbits infused with branched\u2010chain amino acids (leucine, isoleucine and valine) and\u03b1<\/jats:italic>\u2010ketoisocaproate. The branched\u2010chain amino acids (BCAA) and\u03b1<\/jats:italic>\u2010ketoisocaproate blood levels were close to those previously observed in neonates with maple syrup urine disease when extracorporeal blood purification was required. VVHF and VVHDF performances were assessed with two different blood flows ( and 16.6 ml\/min). VVHDF was performed with four dialysate flow rates ( and 3.0 L\/h).<\/jats:p>Within each period, clearances of the three BCAA were strictly similar. BCAA clearances obtained by VVHF were similar to ultrafiltration rates (respectively, 0.78\u00b10.14 and 1.79\u00b10.28 ml\/min at high and low;p<\/jats:italic><0.05). The\u03b1<\/jats:italic>\u2010ketoisocaproate clearances obtained by VVHF were 0.39\u00b10.17 and 0.92\u00b10.43 ml\/min at low and high (not significantly different).<\/jats:p>Whatever the value, the VVHDF procedures always allowed higher BCAA and\u03b1<\/jats:italic>\u2010ketoisocaproate clearances as compared with the corresponding VVHF period with similar. BCAA clearances obtained by VVHDF with a 0.5 L\/h dialysate flow were 4.1\u00b10.5 and 5.4\u00b10.5 mL\/min at low and high, respectively. The concurrent\u03b1<\/jats:italic>\u2010ketoisocaproate clearances were 2.5\u00b10.8 and 2.9\u00b11.0 ml\/min.<\/jats:p>","DOI":"10.1007\/bf01799834","type":"journal-article","created":{"date-parts":[[2005,6,21]],"date-time":"2005-06-21T16:38:06Z","timestamp":1119371886000},"page":"610-620","source":"Crossref","is-referenced-by-count":9,"title":["Removal of branched\u2010chain amino acids and\u03b1<\/i>\u2010ketoisocaproate by haemofiltration and haemodiafiltration"],"prefix":"10.1002","volume":"19","author":[{"given":"J. B.","family":"Gouyon","sequence":"first","affiliation":[{"name":"Laboratoire de N\u00e9phrologie\u2010H\u00e9maph\u00e9r\u00e8se\u2010Transplantation Centre Hospitalier Universitaire Dijon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Semama","sequence":"additional","affiliation":[{"name":"Laboratoire de N\u00e9phrologie\u2010H\u00e9maph\u00e9r\u00e8se\u2010Transplantation Centre Hospitalier Universitaire Dijon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Pr\u00e9vot","sequence":"additional","affiliation":[{"name":"Laboratoire de N\u00e9phrologie\u2010H\u00e9maph\u00e9r\u00e8se\u2010Transplantation Centre Hospitalier Universitaire Dijon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Desgres","sequence":"additional","affiliation":[{"name":"Laboratoire de Biochimie, H\u00f4pital d'Enfants Centre Hospitalier Universitaire Dijon France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1995,3,10]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"803","article-title":"H\u00e9mofiltration art\u00e9rioveineuse continue","volume":"49","author":"Casadevall I","year":"1992","journal-title":"Arch Fr Pediatr"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(79)90638-9"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1542\/peds.25.1.72","article-title":"Maple syrup urine disease: branched\u2010chain ketoaciduria","volume":"25","author":"Dancis J","year":"1960","journal-title":"Pediatrics"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00866350"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1989.tb11130.x"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199403000-00017"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(71)92760-7"},{"key":"e_1_2_1_9_1","first-page":"324","article-title":"Peritoneal dialysis, exchange transfusion and continuous hemodialysis in the management of severe decompensation of branched chain amino acid disorders","volume":"18","author":"Jouvet P","year":"1992","journal-title":"Int Care Med"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(78)90433-3"},{"key":"e_1_2_1_11_1","first-page":"176","article-title":"Renal clearance of branched chain 2\u2010oxo\u2010acids in maple syrup urine disease","volume":"17","author":"Langenbeck U","year":"1979","journal-title":"J Clin Chem Clin Biochem"},{"key":"e_1_2_1_12_1","first-page":"133","article-title":"Traitement d'urgence d'une forme aigu\u00eb de leucinose par dialyse p\u00e9riton\u00e9ale","volume":"26","author":"Rey F","year":"1969","journal-title":"Arch Fr Pediatr"},{"key":"e_1_2_1_13_1","first-page":"674","article-title":"H\u00e4mofiltration bei akuten neonatalen Stoffwechselkrisen","volume":"104","author":"Ring E","year":"1992","journal-title":"Wien Klin Wochenschr"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01706202"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1994.119"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03047365"},{"key":"e_1_2_1_17_1","first-page":"137","volume-title":"Inborn Errors of Metabolism","author":"Saudubray JM","year":"1991"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(80)90600-4"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)82198-5"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00442404"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199402000-00025"}],"container-title":["Journal of Inherited Metabolic Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/BF01799834","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/BF01799834","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T11:45:01Z","timestamp":1694778301000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/BF01799834"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,3,10]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1996,9]]}},"alternative-id":["10.1007\/BF01799834"],"URL":"https:\/\/doi.org\/10.1007\/bf01799834","archive":["Portico"],"relation":{},"ISSN":["0141-8955","1573-2665"],"issn-type":[{"value":"0141-8955","type":"print"},{"value":"1573-2665","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,3,10]]}}}