{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T09:35:32Z","timestamp":1790069732799,"version":"4.0.1"},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[1986,7,7]],"date-time":"1986-07-07T00:00:00Z","timestamp":521078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Inher Metab Disea"],"published-print":{"date-parts":[[1987,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>A study of 2\u2010deoxyglucose transport into polymorphonuclear leukocytes (PMN) was performed in three patients with glycogen storage disease (GSD) type Ib. The rate of 2\u2010deoxyglucose transport into GSD Ib PMN was 30% of that of cells of normal controls. In GSD Ib lymphocytes, transport was normal.<\/jats:p><jats:p>K<jats:sub>m<\/jats:sub> for 2\u2010deoxyglucose in the PMN of one patient was within the normal range.<\/jats:p><jats:p>The reduced transport was not due to the elevation in K<jats:sub>m<\/jats:sub> for 2\u2010deoxyglucose nor to the decreased rate of phosphorylation of 2\u2010deoxyglucose. The striking limitation of glucose transport across the cell membrane may account for the impairment of leukocyte function which is characteristic of GSD Ib.<\/jats:p>","DOI":"10.1007\/bf01800068","type":"journal-article","created":{"date-parts":[[2005,6,21]],"date-time":"2005-06-21T16:59:49Z","timestamp":1119373189000},"page":"234-241","source":"Crossref","is-referenced-by-count":14,"title":["Impaired glucose transport in polymorphonuclear leukocytes in glycogen storage disease Ib"],"prefix":"10.1002","volume":"10","author":[{"given":"N.","family":"Bashan","sequence":"first","affiliation":[{"name":"Pediatric Research Laboratory, Soroka Medical Center and Faculty of Health Sciences Ben\u2010Gurion University of the Negev  Beer Sheva 84105 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Potashnik","sequence":"additional","affiliation":[{"name":"Pediatric Research Laboratory, Soroka Medical Center and Faculty of Health Sciences Ben\u2010Gurion University of the Negev  Beer Sheva 84105 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Hagay","sequence":"additional","affiliation":[{"name":"Pediatric Research Laboratory, Soroka Medical Center and Faculty of Health Sciences Ben\u2010Gurion University of the Negev  Beer Sheva 84105 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. W.","family":"Moses","sequence":"additional","affiliation":[{"name":"Pediatric Research Laboratory, Soroka Medical Center and Faculty of Health Sciences Ben\u2010Gurion University of the Negev  Beer Sheva 84105 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1986,7,7]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-198610000-00119"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0163-7827(81)90134-X"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(80)80418-5"},{"key":"e_1_2_1_5_1","first-page":"838","article-title":"Latency of glucose\u20106\u2010phosphatase (G6P) in type Ib glycogen storage disease (GSD)","volume":"91","author":"Bialik D. S.","year":"1977","journal-title":"J. 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