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The data suggest that mucopolysaccharidosis (MPS) type IVA (Morquio disease), multiple sulphatase deficiency, Niemann\u2010Pick disease type B, GM2 gangliosidosis type \u20180\u2019 (Sandhoff disease), and ceroid lipofuscinosis (Jansky\u2010Bielschowsky and Batten\u2010Spielmeyer\u2010Vogt syndromes) are encountered frequently in Saudi Arabia, as compared to other storage diseases. In contrast, some other diseases such as the adult variant of Gaucher's disease were not observed. Half of the GM2 gangliosidosis type \u20180\u2019 cases originated from one large tribe in the country. Other conditions did not show tribal predilection. The ceroid lipofuscinosis cases in Saudi Arabia originated from four large families. Consanguineous marriages taking place within tribal boundaries probably account for the pattern observed.<\/jats:p>","DOI":"10.1007\/bf01800209","type":"journal-article","created":{"date-parts":[[2005,6,21]],"date-time":"2005-06-21T16:30:05Z","timestamp":1119371405000},"page":"849-861","source":"Crossref","is-referenced-by-count":40,"title":["Prevalence of different types of lysosomal storage diseases in saudi arabia"],"prefix":"10.1002","volume":"13","author":[{"given":"P. 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