{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T04:27:07Z","timestamp":1694752027854},"reference-count":67,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[1989,6,1]],"date-time":"1989-06-01T00:00:00Z","timestamp":612662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Inher Metab Disea"],"published-print":{"date-parts":[[1989,6]]},"DOI":"10.1007\/bf01800725","type":"journal-article","created":{"date-parts":[[2005,6,21]],"date-time":"2005-06-21T17:06:50Z","timestamp":1119373610000},"page":"184-196","source":"Crossref","is-referenced-by-count":9,"title":["Contributions of Lesch\u2010Nyhan syndrome to the understanding of purine metabolism"],"prefix":"10.1002","volume":"12","author":[{"given":"J. E.","family":"Seegmiller","sequence":"first","affiliation":[{"name":"University of California  San Diego, La Jolla CA 92093 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1989,6]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.78.11.6858"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(73)90174-5"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.179.4078.1123"},{"key":"e_1_2_1_5_1","first-page":"387","volume-title":"Third International Symposium of Purine Metabolism in Man, III. Biochem. Immunol. and Cancer Res.","author":"Becker M. A.","year":"1980"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.218284"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)45615-3"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)56639-4"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2787(72)90424-8"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2944(77)90029-1"},{"key":"e_1_2_1_11_1","first-page":"883","article-title":"A new metabolic disease: the complete deficit of adenine phosphoribosyltransferase and lithiasis of 2,8\u2010dihydroxyadenine","volume":"279","author":"Cartier M. P.","year":"1974","journal-title":"CR Acad. Sci. (Paris)"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01531296"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01464036"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197612232952603"},{"key":"e_1_2_1_15_1","volume-title":"A Short History of the Gout","author":"Copeman W. S. C","year":"1964"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/220272a0"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.39.7.656"},{"key":"e_1_2_1_18_1","first-page":"1","volume-title":"Progress in Neuropathology","author":"Fujita A.","year":"1976"},{"key":"e_1_2_1_19_1","doi-asserted-by":"crossref","unstructured":"Garrod A. B.Observations on certain pathological conditions of the blood and urine in gout rheumatism and Bright's disease.Trans. Med\u2010Chir. Soc. (London)(1848)83\u201389.","DOI":"10.1177\/095952874803100109"},{"key":"e_1_2_1_20_1","volume-title":"The Nature and Treatment of Gout and Rheumatic Gout","author":"Garrod A. B.","year":"1859"},{"key":"e_1_2_1_21_1","first-page":"73","article-title":"The Croonian lectures on inborn errors of metabolism. Lecture II. Alkaptonuria","volume":"2","author":"Garrod A. E.","year":"1908","journal-title":"Lancet"},{"key":"e_1_2_1_22_1","volume-title":"Inborn Errors of Metabolism","author":"Garrod A. E.","year":"1923"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(75)91950-9"},{"key":"e_1_2_1_24_1","first-page":"785","article-title":"2,8\u2010dihydroxyadenine urolithiasis: report of a case first diagnosed after renal transplant","volume":"69","author":"Glicklich D.","year":"1988","journal-title":"Q. J. Med."},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3864246"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4684-5104-7_27"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)40020-2"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.2.477"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)42075-1"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI105643"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.57.6.1735"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196802082780601"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI105913"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-70-1-155"},{"key":"e_1_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-91-22295"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-198807000-00102"},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(64)90104-4"},{"key":"e_1_2_1_38_1","first-page":"903","article-title":"The enzymatic spectrophotometric method for determination of uric acid","volume":"54","author":"Liddle L.","year":"1959","journal-title":"J. Lab. Clin. Med."},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-198807000-00089"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1091647"},{"key":"e_1_2_1_41_1","first-page":"1375","article-title":"Effects of 2\u2010amino\u20101,3,4\u2010thiadiazoale on ribonucleotide pools of leukemia L1210 cells","volume":"36","author":"Nelson J. A.","year":"1976","journal-title":"Cancer Res."},{"key":"e_1_2_1_42_1","first-page":"182","article-title":"Mechanism of action of 2\u2010amino\u20101,3,4\u2010thiadiazole (NSC 4728)","volume":"37","author":"Nelson J. A.","year":"1977","journal-title":"Cancer Res."},{"key":"e_1_2_1_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01543464"},{"key":"e_1_2_1_44_1","first-page":"113","article-title":"Bone marrow transplantation in Lesch\u2010Nyhan disease","volume":"22","author":"Nyhan W. L.","year":"1986","journal-title":"Birth Defects"},{"key":"e_1_2_1_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02263652"},{"key":"e_1_2_1_46_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1967.03130160049007"},{"key":"e_1_2_1_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(67)90137-7"},{"key":"e_1_2_1_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2787(68)90512-1"},{"key":"e_1_2_1_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)56968-X"},{"key":"e_1_2_1_50_1","first-page":"777","volume-title":"Metabolic Control and Disease","author":"Seegmiller J. E.","year":"1980"},{"key":"e_1_2_1_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)81421-7"},{"key":"e_1_2_1_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(57)90131-6"},{"key":"e_1_2_1_53_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI104560"},{"key":"e_1_2_1_54_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196303282681306"},{"key":"e_1_2_1_55_1","first-page":"507","article-title":"The effect of 2\u2010ethylamino\u20101,3,4\u2010thiadiazole on the incorporation of glycine into urinary purines and uric acid in man","volume":"12","author":"Seegmiller J. E.","year":"1963","journal-title":"Metabolism"},{"key":"e_1_2_1_56_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.155.3770.1682"},{"key":"e_1_2_1_57_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI105808"},{"key":"e_1_2_1_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(77)90294-7"},{"key":"e_1_2_1_59_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1976.tb00309.x"},{"key":"e_1_2_1_60_1","first-page":"342","article-title":"Metabolic cooperation by cell to cell transfer between genetically different mammalian cells in tissue culture","volume":"21","author":"Subak\u2010Sharpe H.","year":"1966","journal-title":"Heredity"},{"key":"e_1_2_1_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/201395a0"},{"key":"e_1_2_1_62_1","first-page":"688","article-title":"Xanthine oxidase activity in human tissues and its inhibition by allopurinol (4\u2010hydroxypyrazolo (3,4\u2010d) pyrimidine)","volume":"66","author":"Watts R. W. E.","year":"1965","journal-title":"J. Lab. Clin. Med."},{"key":"e_1_2_1_63_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01800063"},{"key":"e_1_2_1_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4684-8559-2_39"},{"key":"e_1_2_1_65_1","first-page":"287","article-title":"Anin vivo andin vitro evaluation of 1\u2010B\u2010d\u2010ribofuranosyl\u20101,2,4\u2010triazole\u20103\u2010carboxamidine; an inhibitor of human lymphoblast purine nucleoside phosphorylase","volume":"18","author":"Willis R. C.","year":"1980","journal-title":"Mol. Pharmacol."},{"key":"e_1_2_1_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)43023-7"},{"key":"e_1_2_1_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)42870-5"},{"key":"e_1_2_1_68_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI108183"}],"container-title":["Journal of Inherited Metabolic Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/BF01800725","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/BF01800725","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T00:43:31Z","timestamp":1694738611000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/BF01800725"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,6]]},"references-count":67,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1989,6]]}},"alternative-id":["10.1007\/BF01800725"],"URL":"https:\/\/doi.org\/10.1007\/bf01800725","archive":["Portico"],"relation":{},"ISSN":["0141-8955","1573-2665"],"issn-type":[{"value":"0141-8955","type":"print"},{"value":"1573-2665","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,6]]}}}