{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T11:02:46Z","timestamp":1697886166775},"reference-count":9,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[1978,9,6]],"date-time":"1978-09-06T00:00:00Z","timestamp":273888000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Inher Metab Disea"],"published-print":{"date-parts":[[1979,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>4\u2010Methylumbelliferyl\u2010\u03b1\u2010<jats:sc>l<\/jats:sc>\u2010iduronide provided a more sensitive method than phenyl\u2010\u03b1\u2010<jats:sc>l<\/jats:sc>\u2010iduronide for the estimation of \u03b1\u2010<jats:sc>l<\/jats:sc>\u2010iduronidase in cultured cells and could be used to diagnose Hurler's disease. The 4\u2010methylumbelliferyl derivative was no more useful than the phenyl derivative for the detection of heterozygotes. All ten lysosomal enzymes tested could be used as reference enzymes when cell extracts were prepared by freeze\/thawing in distilled water, but only<jats:italic>N<\/jats:italic>\u2010acetyl\u2010\u03b2\u2010<jats:sc>d<\/jats:sc>\u2010glucosaminidase could be used for extracts prepared by freeze\/thawing in formate buffer pH 3.5 containing 150 mmol\/l sodium chloride.<\/jats:p>","DOI":"10.1007\/bf01801722","type":"journal-article","created":{"date-parts":[[2005,6,27]],"date-time":"2005-06-27T23:52:57Z","timestamp":1119916377000},"page":"71-74","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of the substrate 4\u2010Methylumbelliferyl\u2010\u03b1\u2010<scp>l<\/scp>\u2010iduronide with phenyl\u2010\u03b1\u2010<scp>l<\/scp>\u2010iduronide for the diagnosis of Hurler's disease in cultured cells"],"prefix":"10.1002","volume":"2","author":[{"given":"J.","family":"Butterworth","sequence":"first","affiliation":[{"name":"Department of Pathology Royal Hospital for Sick Children and University of Edinburgh  Edinburgh EH9 1LF Scotland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. M.","family":"Broadhead","sequence":"additional","affiliation":[{"name":"Department of Pathology Royal Hospital for Sick Children and University of Edinburgh  Edinburgh EH9 1LF Scotland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1978,9,6]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1042\/bst0010231"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1977.tb00944.x"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01805711"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1978.tb02109.x"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(78)90253-X"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)52451-6"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(78)90441-5"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(74)90212-5"},{"key":"e_1_2_1_10_1","first-page":"265","article-title":"The inhibitory effect of halide ions on human polymorphonuclear leukocyte neuraminidase","volume":"1","author":"Yeh A. K.","year":"1976","journal-title":"J. Mol. Med."}],"container-title":["Journal of Inherited Metabolic Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/BF01801722","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/BF01801722","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T23:43:21Z","timestamp":1694907801000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/BF01801722"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,9,6]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1979,9]]}},"alternative-id":["10.1007\/BF01801722"],"URL":"https:\/\/doi.org\/10.1007\/bf01801722","archive":["Portico"],"relation":{},"ISSN":["0141-8955","1573-2665"],"issn-type":[{"value":"0141-8955","type":"print"},{"value":"1573-2665","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,9,6]]}}}