{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T02:35:47Z","timestamp":1791772547643,"version":"4.3.4"},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[1988,11,9]],"date-time":"1988-11-09T00:00:00Z","timestamp":595036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Inher Metab Disea"],"published-print":{"date-parts":[[1989,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Treatment for phenylketonuria (PKU) involves using low phenylalanine or phenylalanine\u2010free formulas and supplementation with sufficient phenylalanine for normal growth and development. Eighteen infants with phenylketonuria who received breast milk as their primary phenylalanine source were compared with ten other infants with PKU who received their phenylalanine primarily from infant formulas. There were no significant differences between breast\u2010fed and formula\u2010fed infants for serum phenylalanine, serum tyrosine, length, weight, head circumference, haematocrit, haemoglobin, serum iron, total iron binding capacity, percentage iron saturation, ferritin, plasma zinc and total calorie intake. Breast\u2010fed infants did show lower mean corpuscular volume at 3 months and 6 months of age. Breast\u2010fed infants had lower phenylalanine intake at 2, 4, 5 and 6 months of age. Breast\u2010fed infants at 1, 2, 3, 4, 5 and 6 months of age had lower protein intake. Breast feeding may be continued in the newly diagnosed phenylketonuric infant without any apparent adverse nutritional consequences.<\/jats:p>","DOI":"10.1007\/bf01802044","type":"journal-article","created":{"date-parts":[[2005,6,27]],"date-time":"2005-06-27T23:58:04Z","timestamp":1119916684000},"page":"467-474","source":"Crossref","is-referenced-by-count":18,"title":["The management of breast feeding among infants with phenylketonuria"],"prefix":"10.1002","volume":"12","author":[{"given":"L.","family":"McCabe","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Colorado Health Sciences Center  Denver Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. E.","family":"Ernest","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado Health Sciences Center  Denver Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. R.","family":"Neifert","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado Health Sciences Center  Denver Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Yannicelli","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado Health Sciences Center  Denver Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. M.","family":"Nord","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado Health Sciences Center  Denver Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. J.","family":"Garry","sequence":"additional","affiliation":[{"name":"Clinical Nutrition Laboratory University of New Mexico School of Medicine  Albuquerque New Mexico USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. R. B.","family":"McCabe","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado Health Sciences Center  Denver Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1988,11,9]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607181005005406"},{"key":"e_1_2_1_3_1","volume-title":"Diet Management of PKU for Infants and Preschool Children","author":"Acosta P. B.","year":"1977"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1542\/peds.68.3.394","article-title":"Availability of zinc: loading tests with human milk, cow's milk, and infant formulas","volume":"68","author":"Casey C. E.","year":"1981","journal-title":"Pediatrics"},{"key":"e_1_2_1_5_1","unstructured":"Consumer Nutrition Center.Comparison of Foods Raw Processed Prepared. US Department of Agriculture Handbook 8 Sections 8\u20101 to 8\u20109 Washington DC 1976."},{"key":"e_1_2_1_6_1","volume-title":"Guide to Breast Feeding the Infant with PKU","author":"Ernest A. E.","year":"1979"},{"key":"e_1_2_1_7_1","volume-title":"Infant Nutrition","author":"Fomon S. J.","year":"1974"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(79)80025-6"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/29.10.1134"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/29.10.1127"},{"key":"e_1_2_1_11_1","first-page":"125","article-title":"The protein content of human milk. I. A transversal study of Swedish normal material","volume":"13","author":"Lonnerdal B.","year":"1976","journal-title":"Nutr. Rept. Intern."},{"key":"e_1_2_1_12_1","first-page":"589","article-title":"Compostion of human colostrum and milk","volume":"78","author":"Macy I. G.","year":"1949","journal-title":"Am. J. Dis. 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