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Urinary succinylacetone (SA) was detected in her urine prior to transplantation despite strict adherence to a low\u2010tyrosine diet. Other patients with severe liver disease awaiting liver transplantation do not excrete SA in the urine. She continued to excrete SA during the postoperative period despite normal liver functions. Oral tyrosine loading resulted in significant elevation of SA excretion. Possible explanations for this observation and clinical and therapeutic relevance are discussed.<\/jats:p>","DOI":"10.1007\/bf01805479","type":"journal-article","created":{"date-parts":[[2005,6,27]],"date-time":"2005-06-27T22:39:58Z","timestamp":1119911998000},"page":"21-24","source":"Crossref","is-referenced-by-count":18,"title":["Persistent succinylacetone excretion after liver transplantation in a patient with hereditary tyrosinaemia type I"],"prefix":"10.1002","volume":"8","author":[{"given":"M.","family":"Tuchman","sequence":"first","affiliation":[{"name":"Departments of Pediatrics and Surgery University of Minnesota  516 Delaware Street S.E. Minneapolis MN 55455 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. K.","family":"Freese","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics and Surgery University of Minnesota  516 Delaware Street S.E. Minneapolis MN 55455 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. 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