{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T19:01:26Z","timestamp":1761764486705},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[1978,11,30]],"date-time":"1978-11-30T00:00:00Z","timestamp":281232000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Inher Metab Disea"],"published-print":{"date-parts":[[1978,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A collagen\u2010type pattern of peptide and amino acid spots was obtained when partial hydrolysates of normal human dermis were examined by a specially developed thin\u2010layer chromatographic (TLC) \u2018finger\u2010printing\u2019 technique. The pattern was consistent and independent of age and sex. Two clinically similar cases of osteogenesis imperfecta congenita gave identical patterns which differed in specific regions from those given by their age\u2010matched, normal controls. A single case of osteogenesis imperfecta tarda showed the same overall pattern as the congenita cases. It is concluded that an abnormal amino acid sequence occurs in the collagen molecule of both types of osteogenesis imperfecta.<\/jats:p>","DOI":"10.1007\/bf01805580","type":"journal-article","created":{"date-parts":[[2005,6,28]],"date-time":"2005-06-28T00:02:21Z","timestamp":1119916941000},"page":"123-128","source":"Crossref","is-referenced-by-count":2,"title":["Osteogenesis imperfecta: Evidence for the existence of an abnormal amino acid sequence in the molecule of dermal collagen"],"prefix":"10.1002","volume":"1","author":[{"given":"J. G.","family":"Heathcote","sequence":"first","affiliation":[{"name":"The Department of Biochemistry The University of Salford  M5 4WT UK"},{"name":"The Skin Hospital The University of Manchester School of Medicine  M3 3HL UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samirah","family":"Al\u2010Alawi","sequence":"additional","affiliation":[{"name":"The Department of Biochemistry The University of Salford  M5 4WT UK"},{"name":"The Skin Hospital The University of Manchester School of Medicine  M3 3HL UK"},{"name":"Department of Biomedical Chemistry Al Mustansiriyah University  Baghdad"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1978,11,30]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.57B1.2"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00446347"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.183.4130.1200"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02013724"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5905.421"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(00)87781-X"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(76)93146-9"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/003693307702200127"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-197509020-00005"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01468935"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1975.tb02429.x"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.72.2.586"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4757-4602-0_1"},{"key":"e_1_2_1_15_1","first-page":"501","article-title":"Osteogenesis imperfecta congenita. Evidence for a generalized molecular disorder of collagen","volume":"36","author":"Trelstad R. L.","year":"1977","journal-title":"Lab. Invest."}],"container-title":["Journal of Inherited Metabolic Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/BF01805580","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/BF01805580","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T19:50:10Z","timestamp":1694893810000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/BF01805580"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,11,30]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1978,12]]}},"alternative-id":["10.1007\/BF01805580"],"URL":"https:\/\/doi.org\/10.1007\/bf01805580","archive":["Portico"],"relation":{},"ISSN":["0141-8955","1573-2665"],"issn-type":[{"value":"0141-8955","type":"print"},{"value":"1573-2665","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,11,30]]}}}