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By means of analyses of malate in the cytosolic and particulate fractions of the fibroblasts the differences in pH between these two cellular compartments were estimated to be 1.34\u00b10.12 and 1.38\u00b10.18 for control and patient, respectively. Neither difference was statistically significant. The decrease in the rate of ornithine uptake by mitochondria of the patient's fibroblast is therefore not due to an increased intramitochondrial pH.<\/jats:p>","DOI":"10.1007\/bf01805611","type":"journal-article","created":{"date-parts":[[2005,6,27]],"date-time":"2005-06-27T23:53:45Z","timestamp":1119916425000},"page":"9-11","source":"Crossref","is-referenced-by-count":7,"title":["The pH of mitochondria of fibroblasts from a hyperornithinaemia, hyperammonaemia, homocitrullinuria\u2010syndrome patient"],"prefix":"10.1002","volume":"7","author":[{"given":"K.","family":"Metoki","sequence":"first","affiliation":[{"name":"Department of Cell and Molecular Biology Medical College of Georgia  Augusta GA 30912 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. 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