{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T01:25:00Z","timestamp":1759541100574},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1983,4,18]],"date-time":"1983-04-18T00:00:00Z","timestamp":419472000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Inher Metab Disea"],"published-print":{"date-parts":[[1984,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hair\u2010 and serum\u2010zinc concentrations were measured in six patients with acrodermatitis enteropathica before and sequentially after cessation of zinc supplementation; supplementation was restarted when symptoms appeared. Serum zinc correlated accurately with zinc dosage and was lowest when symptoms of deficiency appeared. Hair zinc was initially age\u2010 and body size\u2010related and was minimally influenced by the supplementation break. Adult patients had continuously normal concentrations. In paediatric patients hair zinc was low. Their serum concentrations should probably be maintained slightly above or at the upper limit of reference values for prolonged periods for normalization of hair and perhaps tissue zinc contents.<\/jats:p>","DOI":"10.1007\/bf01805623","type":"journal-article","created":{"date-parts":[[2005,6,27]],"date-time":"2005-06-27T23:53:45Z","timestamp":1119916425000},"page":"46-48","source":"Crossref","is-referenced-by-count":13,"title":["Serum and hair zinc as predictors of clinical symptoms in acrodermatitis enteropathica"],"prefix":"10.1002","volume":"7","author":[{"given":"P.","family":"Anttila","sequence":"first","affiliation":[{"name":"Department of Paediatrics University of Helsinki  Helsinki 29 00290 Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Simell","sequence":"additional","affiliation":[{"name":"Department of Paediatrics University of Helsinki  Helsinki 29 00290 Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Salmela","sequence":"additional","affiliation":[{"name":"Department of Public Health Science University of Helsinki  Helsinki 29 00290 Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Vuori","sequence":"additional","affiliation":[{"name":"Department of Public Health Science University of Helsinki  Helsinki 29 00290 Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1983,4,18]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(75)92287-4"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0954-6820.1978.tb08400.x"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/31.7.1175"},{"key":"e_1_2_1_5_1","first-page":"81","volume-title":"Zinc and Copper in Clinical Medicine","author":"Hambidge K. M.","year":"1978"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/23.3.284"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00439007"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(74)91772-3"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.110.5.711"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-2670(01)85057-1"}],"container-title":["Journal of Inherited Metabolic Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/BF01805623","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/BF01805623","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T16:59:59Z","timestamp":1694883599000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/BF01805623"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,4,18]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1984,3]]}},"alternative-id":["10.1007\/BF01805623"],"URL":"https:\/\/doi.org\/10.1007\/bf01805623","archive":["Portico"],"relation":{},"ISSN":["0141-8955","1573-2665"],"issn-type":[{"value":"0141-8955","type":"print"},{"value":"1573-2665","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,4,18]]}}}