{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T04:56:05Z","timestamp":1776142565234,"version":"3.50.1"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[1994,11,1]],"date-time":"1994-11-01T00:00:00Z","timestamp":783648000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer Causes Control"],"published-print":{"date-parts":[[1994,11]]},"DOI":"10.1007\/bf01831382","type":"journal-article","created":{"date-parts":[[2005,6,28]],"date-time":"2005-06-28T03:49:20Z","timestamp":1119930560000},"page":"540-548","source":"Crossref","is-referenced-by-count":24,"title":["Dietary lactose intake, lactose intolerance, and the risk of epithelial ovarian cancer in southern Ontario (Canada)"],"prefix":"10.1007","volume":"5","author":[{"given":"Harvey A.","family":"Risch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meera","family":"Jain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Loraine D.","family":"Marrett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geoffrey R.","family":"Howe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF01831382_CR1","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1056\/NEJM198104233041702","volume":"304","author":"FR Kaufman","year":"1981","unstructured":"Kaufman FR, Kogut MD, Donnell GN, Goebelsmann U, March C, Koch R. Hypergonadotropic hypogonadism in female patients with galactosemia.N Engl J Med 1981;304: 994\u20138.","journal-title":"N Engl J Med"},{"key":"BF01831382_CR2","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1007\/BF01799450","volume":"9","author":"FR Kaufman","year":"1986","unstructured":"Kaufman FR, Donnell GN, Roe TF, Kogut MD. Gonadal function in patients with galactosemia.J Inher Metab Dis 1986;9: 140\u20136.","journal-title":"J Inher Metab Dis"},{"key":"BF01831382_CR3","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1056\/NEJM198108203050819","volume":"305","author":"B Steinmann","year":"1981","unstructured":"Steinmann B, Gitzelmann R, Zachmann M. Hypogonadism and galactosemia.N Engl J Med 1981;305: 464\u20135.","journal-title":"N Engl J Med"},{"key":"BF01831382_CR4","first-page":"321","volume":"39","author":"Y Dessart","year":"1982","unstructured":"Dessart Y, Odi\u00e8vre M, Evain D, Chaussain JL. Insuffisance ovarienne et galactos\u00e9mie cong\u00e9nitale.Arch Fr Pediatr 1982;39: 321\u20132.","journal-title":"Arch Fr Pediatr"},{"key":"BF01831382_CR5","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1111\/j.1471-0528.1984.tb05908.x","volume":"91","author":"ACR Robinson","year":"1984","unstructured":"Robinson ACR, Dockeray CJ, Cullen MJ, Sweeney EC. Hypergonadotrophic hypogonadism in classical galactosemia: evidence for defective oogenesis. Case report.Br J Obstet Gynaecol 1984;91: 199\u2013200.","journal-title":"Br J Obstet Gynaecol"},{"key":"BF01831382_CR6","first-page":"2685","volume":"13","author":"P Beauvais","year":"1984","unstructured":"Beauvais P, Guilhaume A, L'insuffisance ovarienne de la galactos\u00e9mie cong\u00e9nitale.Presse M\u00e9d 1984;13: 2685\u20137.","journal-title":"Presse M\u00e9d"},{"key":"BF01831382_CR7","first-page":"133","volume":"4","author":"IS Fraser","year":"1986","unstructured":"Fraser IS, Russell P, Greco S, Robertson DM. Resistant ovary syndrome and premature ovarian failure in young women with galactosemia.Clin Reprod Fertil 1986;4: 133\u20138.","journal-title":"Clin Reprod Fertil"},{"key":"BF01831382_CR8","first-page":"660","volume":"135","author":"E Schober","year":"1987","unstructured":"Schober E, Scheibenreiter S, Frisch H. Gonadotropinsekretion bie Kindern mit Galaktos\u00e4mie.Monatsschr Kinderbeilkd 1987;135: 660\u20132.","journal-title":"Monatsschr Kinderbeilkd"},{"key":"BF01831382_CR9","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1007\/BF01800204","volume":"13","author":"DD Waggoner","year":"1990","unstructured":"Waggoner DD, Buist NRM, Donnell GN. Long-term prognosis in galactosaemia: results of a survey of 350 cases.J Inher Metab Dis 1990;13: 802\u201318.","journal-title":"J Inher Metab Dis"},{"key":"BF01831382_CR10","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1016\/S0022-3476(88)80697-8","volume":"112","author":"FR Kaufman","year":"1988","unstructured":"Kaufman FR, Xu YK, Ng WG, Donnell GN. Correlation of ovarian function with galactose-1-phosphate uridyl transferase levels in galactosemia.J Pediatr 1988;112: 754\u20136.","journal-title":"J Pediatr"},{"key":"BF01831382_CR11","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1203\/00006450-198902000-00015","volume":"25","author":"YK Xu","year":"1989","unstructured":"Xu YK, Ng WG, Kaufman FR, Lobo RA, Donnell GN. Galactose metabolism in human ovarian tissue.Pediatr Res 1989;25: 151\u20135.","journal-title":"Pediatr Res"},{"key":"BF01831382_CR12","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1530\/acta.0.1200129","volume":"120","author":"FR Kaufman","year":"1989","unstructured":"Kaufman FR, Xu YK, Ng WG, Silva PD, Lobo RA, Donnell GN. Gonadal function and ovarian galactose metabolism in classic galactosemia.Act Endocrinol 1989;120: 129\u201333.","journal-title":"Act Endocrinol"},{"key":"BF01831382_CR13","first-page":"397","volume":"8","author":"WU Gardner","year":"1948","unstructured":"Gardner WU. Hormonal imbalances in tumorigenesis.Cancer Res 1948;8: 397\u2013411.","journal-title":"Cancer Res"},{"key":"BF01831382_CR14","first-page":"717","volume":"71","author":"DW Cramer","year":"1983","unstructured":"Cramer DW, Welch WR. Determinants of ovarian cancer risk. II. Inferences regarding pathogenesis.JNCI 1983;71: 717\u201321.","journal-title":"JNCI"},{"key":"BF01831382_CR15","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1093\/jnci\/86.18.1409","volume":"86","author":"HA Risch","year":"1994","unstructured":"Risch HA, Jain M, Marrett LD, Howe GR. Dietary fat intake and the risk of epithelial ovarian cancer.JNCI 1994;86: 1409\u201315.","journal-title":"JNCI"},{"key":"BF01831382_CR16","doi-asserted-by":"crossref","unstructured":"Risch HA, Marrett LD, Howe GR. Parity, contraception, infertility and the risk of epithelial ovarian cancer.Am J Epidemiol, in press.","DOI":"10.1093\/oxfordjournals.aje.a117296"},{"key":"BF01831382_CR17","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1093\/oxfordjournals.aje.a112568","volume":"107","author":"RW Morgan","year":"1978","unstructured":"Morgan RW, Jain M, Miller AB, et al. A comparison of dietary methods in epidemiologic studies.Am J Epidemiol 1978;107: 488\u201398.","journal-title":"Am J Epidemiol"},{"key":"BF01831382_CR18","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1093\/oxfordjournals.aje.a115146","volume":"129","author":"M Jain","year":"1989","unstructured":"Jain M, Howe GR, Harrison L, Miller AB. A study of repeatability of dietary data over a seven-year period.Am J Epidemiol 1989;129: 422\u20139.","journal-title":"Am J Epidemiol"},{"key":"BF01831382_CR19","series-title":"US Department of Agriculture Handbook","volume-title":"Composition of Foods: Raw, Processed, Prepared","author":"US Department of Agriculture, Agriculture Research Service","year":"1972","unstructured":"US Department of Agriculture, Agriculture Research Service,Composition of Foods: Raw, Processed, Prepared. Washington, DC: US Government Printing Office, 1972; US Department of Agriculture Handbook No. 8."},{"key":"BF01831382_CR20","volume-title":"Nutrient Value of Some Common Foods","author":"Health and Welfare Canada","year":"1971","unstructured":"Health and Welfare Canada.Nutrient Value of Some Common Foods. Ottawa, Canada: Information Canada, 1971."},{"key":"BF01831382_CR21","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0315-5463(72)74114-0","volume":"5","author":"D Arthur","year":"1972","unstructured":"Arthur D. Selenium content of Canadian foods.Can Inst Food Sci Technol J 1972;5: 165\u20139.","journal-title":"Can Inst Food Sci Technol J"},{"key":"BF01831382_CR22","series-title":"US Department of Agriculture Home Economics Research Report","volume-title":"Sugar Content of Selected Foods: Individual and Total Sugars","author":"RH Matthews","year":"1987","unstructured":"Matthews RH, Pehrsson PR, Farhat-Sabet M,Sugar Content of Selected Foods: Individual and Total Sugars. Washington, DC: US Government Printing Office, 1987; US Department of Agriculture Home Economics Research Report No. 48."},{"key":"BF01831382_CR23","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/BF01800599","volume":"14","author":"KC Gross","year":"1991","unstructured":"Gross KC, Acosta PB. Fruits and vegetables as a source of galactose: implications in planning the diets of patients with galactosaemia.J Inher Metab Dis 1991;14: 253\u20138.","journal-title":"J Inher Metab Dis"},{"issue":"Suppl 4","key":"BF01831382_CR24","first-page":"1079","volume":"48","author":"NS Scrimshaw","year":"1988","unstructured":"Scrimshaw NS, Murray EB. The acceptability of milk and milk products in populations with a high prevalence of lactose intolerance.Am J Clin Nutr 1988;48 (Suppl 4) 1079\u2013159.","journal-title":"Am J Clin Nutr"},{"key":"BF01831382_CR25","volume-title":"The GLIM System. Rel 3","author":"RJ Baker","year":"1978","unstructured":"Baker RJ, Nelder JA.The GLIM System. Rel 3. Oxford, UK: Royal Statistical Society, 1978."},{"key":"BF01831382_CR26","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1093\/oxfordjournals.aje.a116113","volume":"134","author":"BL Harlow","year":"1991","unstructured":"Harlow BL, Cramer DW, Geller J, Willett WC, Bell DA, Welch WR. The influence of lactose consumption on the association of oral contraceptive use and ovarian cancer risk.Am J Epidemiol 1991;134: 445\u201353.","journal-title":"Am J Epidemiol"},{"key":"BF01831382_CR27","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1002\/ijc.2910260609","volume":"26","author":"M Jain","year":"1980","unstructured":"Jain M, Cook GM, Davis FG, Grace MG, Howe GR, Miller AB. A case-control study of diet and colo-rectal cancer.Int J Cancer 1980;26: 757\u201368.","journal-title":"Int J Cancer"},{"key":"BF01831382_CR28","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1002\/ijc.2910450405","volume":"45","author":"GR Howe","year":"1990","unstructured":"Howe GR, Jain M, Miller AB. Dietary factors and risk of pancreatic cancer: results of a Canadian populationbased case-control study.Int J Cancer 1990;45: 604\u20138.","journal-title":"Int J Cancer"},{"key":"BF01831382_CR29","first-page":"140","volume-title":"Principles of nutritional assessment","author":"RS Gibson","year":"1990","unstructured":"Gibson RS. Principles of nutritional assessment. New York, NY (USA): Oxford University Press, 1990: 140, 608."},{"key":"BF01831382_CR30","first-page":"33","volume-title":"Recommended Dietary Allowances","author":"Food and Nutrition Board, Subcommittee on the Tenth Edition of the RDAs","year":"1989","unstructured":"Food and Nutrition Board, Subcommittee on the Tenth Edition of the RDAs.Recommended Dietary Allowances, 10th Edition. Washington, DC: National Academy Press, 1989: 33.","edition":"10th Edition"},{"key":"BF01831382_CR31","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1093\/oxfordjournals.aje.a112888","volume":"111","author":"M Jain","year":"1980","unstructured":"Jain M, Howe GR, Johnson KC, Miller AB. Evaluation of a diet history questionnaire for epidemiologic studies.Am J Epidemiol 1980;111: 212\u20139.","journal-title":"Am J Epidemiol"},{"key":"BF01831382_CR32","first-page":"663","volume":"79","author":"C LaVecchia","year":"1987","unstructured":"LaVecchia C, Decarli A, Negri E, et al. Dietary factors and the risk of epithelial ovarian cancer.JNCI 1987;79: 663\u20139.","journal-title":"JNCI"},{"key":"BF01831382_CR33","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/0895-4356(88)90164-3","volume":"128","author":"M Mori","year":"1988","unstructured":"Mori M, Harabuchi I, Miyake H, Casagrande JT, Henderson BE, Ross RK. Reproductive, genetic, and dietary risk factors for ovarian cancer.Am J Epidemiol 1988;128: 771\u20137.","journal-title":"Am J Epidemiol"},{"key":"BF01831382_CR34","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/bjc.1989.18","volume":"59","author":"XO Shu","year":"1989","unstructured":"Shu XO, Gao YT, Yuan JM, Ziegler RG, Brinton LA. Dietary factors and epithelial ovarian cancer.Br J Cancer 1989;59: 92\u20136.","journal-title":"Br J Cancer"},{"key":"BF01831382_CR35","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1080\/01635589109514132","volume":"15","author":"A Engle","year":"1991","unstructured":"Engle A, Muscat JE, Harris RE. Nutritional risk factors and ovarian cancer.Nutr Cancer 1991;15: 239\u201347.","journal-title":"Nutr Cancer"},{"key":"BF01831382_CR36","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1002\/ijc.2910550314","volume":"55","author":"A Tzonou","year":"1993","unstructured":"Tzonou A, Hsieh C-c, Polychronopoulou A, et al. Diet and ovarian cancer: a case-control study in Greece.Int J Cancer 1993;55: 411\u20134.","journal-title":"Int J Cancer"},{"key":"BF01831382_CR37","unstructured":"Herrinton LJ, Weiss NS, Beresford SAA,et al. Lactose and galactose intake and metabolism in relation to the risk of epithelial ovarian cancer. (Submitted)."},{"key":"BF01831382_CR38","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1093\/oxfordjournals.aje.a115729","volume":"132","author":"CJ Mettlin","year":"1990","unstructured":"Mettlin CJ, Piver MS. A case-control study of milkdrinking and ovarian cancer risk.Am J Epidemiol 1990;132: 871\u20136.","journal-title":"Am J Epidemiol"},{"key":"BF01831382_CR39","first-page":"833","volume":"63","author":"DW Cramer","year":"1984","unstructured":"Cramer DW, Welch WR, Hutchison GB, Willett W, Scully RE. Dietary animal fat in relation to ovarian cancer risk.Obstet Gynecol 1984;63: 833\u20138.","journal-title":"Obstet Gynecol"},{"key":"BF01831382_CR40","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/S0140-6736(89)90313-9","volume":"2","author":"DW Cramer","year":"1989","unstructured":"Cramer DW, Harlow BL, Willett WC et al. Galactose consumption and metabolism in relation to the risk of ovarian cancer.Lancet 1989;2: 66\u201371.","journal-title":"Lancet"},{"key":"BF01831382_CR41","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1093\/oxfordjournals.aje.a116114","volume":"134","author":"DW Cramer","year":"1991","unstructured":"Cramer DW, Harlow BL. Commentary: Re: \u2018A casecontrol study of milk drinking and ovarian cancer risk.\u2019Am J Epidemiol 1991;134: 454\u20136.","journal-title":"Am J Epidemiol"},{"key":"BF01831382_CR42","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1093\/oxfordjournals.aje.a115423","volume":"130","author":"DW Cramer","year":"1989","unstructured":"Cramer DW. Lactase persistence and milk consumption as determinanst of ovarian cancer risk.Am J Epidemiol 1989;130: 904\u201310.","journal-title":"Am J Epidemiol"},{"key":"BF01831382_CR43","first-page":"219","volume-title":"Metabolic Effects of Dietary Carbohydrates","author":"CA Williams","year":"1986","unstructured":"Williams CA. Metabolism of lactose and galactose in man. In: Macdonald I, Vr\u00e1na A, eds.Metabolic Effects of Dietary Carbohydrates. Basel, Switzerland: Karger, 1986: 219\u201347."},{"key":"BF01831382_CR44","first-page":"131","volume-title":"Physiological Chemistry of Carbohydrates in Mammals","author":"WW Shreeve","year":"1974","unstructured":"Shreeve WW.Physiological Chemistry of Carbohydrates in Mammals. Philadelphia, PA (USA): WB Saunders Co., 1974; 131\u20132."},{"key":"BF01831382_CR45","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1007\/BF01799506","volume":"13","author":"S Segal","year":"1990","unstructured":"Segal S, Rogers S. Regulation of galactose metabolism: implications for therapy.J Inher Metab Dis 1990;13: 487\u2013500.","journal-title":"J Inher Metab Dis"},{"key":"BF01831382_CR46","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/0026-0495(83)90189-0","volume":"32","author":"CA Williams","year":"1983","unstructured":"Williams CA, Phillips T, Macdonald I. The influence of glucose on serum galactose levels in man.Metabolism 1983;32: 250\u20136.","journal-title":"Metabolism"},{"key":"BF01831382_CR47","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1203\/00006450-199310000-00006","volume":"34","author":"RA Heidenreich","year":"1994","unstructured":"Heidenreich RA, Mallee J, Rogers S, Segal S. Developmental and tissue-specific modulation of rat galactose-1-phosphate uridyltransferase steady state messenger RNA and specific activity levels.Pediatr Res 1994;34: 416\u20139.","journal-title":"Pediatr Res"},{"key":"BF01831382_CR48","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S0015-0282(16)60608-8","volume":"51","author":"DW Cramer","year":"1989","unstructured":"Cramer DW, harlow BL, Barbieri RL, Ng WG. Galactose-1-phosphate uridyl transferase activity associated with age at menopause and reproductive history.Fertil Steril 1989;51: 609\u201315.","journal-title":"Fertil Steril"},{"key":"BF01831382_CR49","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/0026-0495(92)90321-Z","volume":"41","author":"GT Berry","year":"1992","unstructured":"Berry GT, Palmieri MJ, Heales S, Leonard JV, Segal S. Red blood cell uridine sugar nucleotide levels in patients with classic galactosemia and other metabolic disorders.Metabolism 1992;41: 783\u20137.","journal-title":"Metabolism"},{"key":"BF01831382_CR50","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/S0022-3476(05)80386-5","volume":"123","author":"JB Gibson","year":"1993","unstructured":"Gibson JB, Reynolds RA, Rogers S, Palmieri MJ, Segal S. Uridine diphosphoglucose content of human erythrocytes: assessment by conversion to uridine diphosphoglucuronate.J Pediatr 1993;123: 906\u201314.","journal-title":"J Pediatr"},{"key":"BF01831382_CR51","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/S0022-3476(05)80404-4","volume":"123","author":"JB Holton","year":"1993","unstructured":"Holton JB, de la Cruz F, Levy HL. Galactosemia: the uridine diphosphate galactose deficiency-uridine treatment controversy.J Pediatr 1993;123: 1009\u201314.","journal-title":"J Pediatr"},{"key":"BF01831382_CR52","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/BF01799215","volume":"12","author":"WG Ng","year":"1989","unstructured":"Ng WG, Xu YK, Kaufman FR, Donnell GN. Deficit of uridine diphosphate galactose in galactosaemia.J Inher Metab Dis 1989;12: 257\u201366.","journal-title":"J Inher Metab Dis"},{"key":"BF01831382_CR53","first-page":"190","volume":"3","author":"K Helzlsouer","year":"1994","unstructured":"Helzlsouer K, Alberg A, Gordon G, Bush T, Longcope C, Comstock G. Serum gonadotropic and steriod hormones in relation to the risk of developing ovarian cancer.Cancer Epidemiol Biomarkers Prev 1994;3: 190.","journal-title":"Cancer Epidemiol Biomarkers Prev"}],"container-title":["Cancer Causes & Control"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01831382.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01831382\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01831382","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T19:05:23Z","timestamp":1557428723000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01831382"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,11]]},"references-count":53,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1994,11]]}},"alternative-id":["BF01831382"],"URL":"https:\/\/doi.org\/10.1007\/bf01831382","relation":{},"ISSN":["0957-5243","1573-7225"],"issn-type":[{"value":"0957-5243","type":"print"},{"value":"1573-7225","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,11]]}}}