{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T10:59:43Z","timestamp":1758279583325},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1976,12,1]],"date-time":"1976-12-01T00:00:00Z","timestamp":218246400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Membrain Biol."],"published-print":{"date-parts":[[1976,12]]},"DOI":"10.1007\/bf01869137","type":"journal-article","created":{"date-parts":[[2005,7,1]],"date-time":"2005-07-01T14:11:01Z","timestamp":1120227061000},"page":"207-232","source":"Crossref","is-referenced-by-count":9,"title":["Irreversible activation of adenylate cyclase of toad erythrocyte plasma membrane by 5\u2032-guanylylimidodiphosphate"],"prefix":"10.1007","volume":"27","author":[{"given":"Vann","family":"Bennett","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Cuatrecasas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF01869137_CR1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF01868161","volume":"22","author":"V. Bennett","year":"1975","unstructured":"Bennett, V., Cuatrecasas, P. 1975a. Mechanism of action ofVibrio cholerae enterotoxin: Effects on adenylate cyclase of toad and rat erythrocyte plasma membranes.J. Membrane Biol. 22:1","journal-title":"J. Membrane Biol."},{"key":"BF01869137_CR2","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/BF01868162","volume":"22","author":"V. Bennett","year":"1975","unstructured":"Bennett, V., Cuatrecasas, P. 1975b. Mechanism of activation of adenylate cyclase byVibrio cholerae enterotoxin.J. Membrane Biol. 22:29","journal-title":"J. Membrane Biol."},{"key":"BF01869137_CR3","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/BF01868618","volume":"24","author":"V. Bennett","year":"1975","unstructured":"Bennett, V., Mong, L., Cuatrecasas, P. 1975a. Mechanism of activation of adenylate cyclase byVibrio cholerae enterotoxin. Relations to the mode of activation by hormones.J. Membrane Biol. 24:107","journal-title":"J. Membrane Biol."},{"key":"BF01869137_CR4","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1073\/pnas.72.1.33","volume":"72","author":"V. Bennett","year":"1975","unstructured":"Bennett, V., O'Keefe, E., Cuatrecasas, P. 1975b. The mechanism of action of cholera toxin and the mobile receptor theory of hormone receptor-adenylate cyclase interactions.Proc. Nat. Acad. Sci. USA 72:33","journal-title":"Proc. Nat. Acad. Sci. USA"},{"key":"BF01869137_CR5","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0021-9258(19)43105-0","volume":"249","author":"J.P. Bilezikian","year":"1974","unstructured":"Bilezikian, J.P., Aurbach, G.D. 1974. The effects of nucleotides on the expression of \u03b2-adrenergic adenylate cyclase activity in membranes from turkey erythrocytes.J. Biol. Chem. 249:157","journal-title":"J. Biol. Chem."},{"key":"BF01869137_CR6","doi-asserted-by":"crossref","first-page":"7073","DOI":"10.1016\/S0021-9258(19)44695-4","volume":"247","author":"J. Bockhaert","year":"1972","unstructured":"Bockhaert, J., Roy, C., Jard, S. 1972. Oxytocin-sensitive adenylate cyclase in frog bladder epithelial cells.J. Biol. Chem. 247:7073","journal-title":"J. Biol. Chem."},{"key":"BF01869137_CR7","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1073\/pnas.72.4.1451","volume":"72","author":"P. Brulet","year":"1975","unstructured":"Brulet, P., McConnell, H.M. 1975. Magnetic resonance spectra of membrane.Proc. Nat. Acad. Sci. USA 72:1457","journal-title":"Proc. Nat. Acad. Sci. USA"},{"key":"BF01869137_CR8","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1146\/annurev.bi.43.070174.001125","volume":"43","author":"P. Cuatrecasas","year":"1974","unstructured":"Cuatrecasas, P. 1974. Membrane receptors.Annu. Rev. Biochem. 43:169","journal-title":"Annu. Rev. Biochem."},{"key":"BF01869137_CR9","first-page":"79","volume-title":"Advances in Cyclic Nucleotide Research","author":"P. Cuatrecasas","year":"1975","unstructured":"Cuatrecasas, P. 1975. Hormone receptors\u2014Their function in cell membranes and some problems related to methodology.In: Advances in Cyclic Nucleotide Research. P. Greengard and G.A. Robison, editors. Vol. 5, p. 79. Raven Press, New York"},{"key":"BF01869137_CR10","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/BF01870253","volume":"23","author":"P. Cuatrecasas","year":"1975","unstructured":"Cuatrecasas, P., Bennett, V., Jacobs, S. 1975a. Irreversible stimulation of adenylate cyclase activity of fat cell membranes by phosphoramidate and phosphonate analogs of GTP.J. Membrane Biol. 23:249","journal-title":"J. Membrane Biol."},{"key":"BF01869137_CR11","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1073\/pnas.72.5.1739","volume":"72","author":"P. Cuatrecasas","year":"1975","unstructured":"Cuatrecasas, P., Jacobs, S., Bennett, V. 1975b. Activation of adenylate cyclase by phosphoramidate and phosphonate analogs of GTP: Possible role of covalent enzyme-substrate intermediates in the mechanism of hormonal activation.Proc. Nat. Acad. Sci. USA 72:1739","journal-title":"Proc. Nat. Acad. Sci. USA"},{"key":"BF01869137_CR12","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0304-4165(73)90004-4","volume":"329","author":"D.J. Deery","year":"1973","unstructured":"Deery, D.J., Howell, S.L. 1973. Rat anterior pituitary adenyl cyclase activity: GTP requirement of prostaglandin E1 and E2 and synthetic luteinizing hormone-releasing hormone activation.Biochim. Biophys. Acta 329:17","journal-title":"Biochim. Biophys. Acta"},{"key":"BF01869137_CR13","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1146\/annurev.bb.03.060174.001143","volume":"3","author":"M. Edidin","year":"1974","unstructured":"Edidin, M. 1974. Rotational and translational diffusion in membranes.Annu. Rev. Biophys. Bioeng. 3:179","journal-title":"Annu. Rev. Biophys. Bioeng."},{"key":"BF01869137_CR14","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1083\/jcb.57.1.27","volume":"57","author":"M. Edidin","year":"1973","unstructured":"Edidin, M., Fambrough, D. 1973. Fluidity of the surface of cultural muscle fibers.J. Cell Biol. 57:27","journal-title":"J. Cell Biol."},{"key":"BF01869137_CR15","doi-asserted-by":"crossref","first-page":"5788","DOI":"10.1016\/S0021-9258(18)62721-8","volume":"245","author":"C. Frieden","year":"1970","unstructured":"Frieden, C. 1970. Kinetic aspects of regulation of metabolic processess.J. Biol. Chem. 245:5788","journal-title":"J. Biol. Chem."},{"key":"BF01869137_CR16","doi-asserted-by":"crossref","first-page":"4653","DOI":"10.1073\/pnas.71.12.4653","volume":"71","author":"C.W.M. Grant","year":"1974","unstructured":"Grant, C.W.M., McConnell, H.M. 1974. Gycophorin in lipid bilayers.Proc. Nat. Acad. Sci. USA 71:4653","journal-title":"Proc. Nat. Acad. Sci. USA"},{"key":"BF01869137_CR17","doi-asserted-by":"crossref","first-page":"6239","DOI":"10.1016\/S0021-9258(19)43534-5","volume":"248","author":"J.P. Harwood","year":"1973","unstructured":"Harwood, J.P., Low, H., Rodbell, M. 1973. Stimulatory and inhibitory effects of guanyl nucleotides on fat cell adenylate cyclase.J. Biol. Chem. 248:6239","journal-title":"J. Biol. Chem."},{"key":"BF01869137_CR18","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1021\/bi00672a026","volume":"14","author":"K. Jacobson","year":"1975","unstructured":"Jacobson, K., Papahadjopoulos, D. 1975. Phase transitions and phase separations in phospholipid membranes induced by changes in temperature, pH, and concentration of bivalent cations.Biochemistry 14:152","journal-title":"Biochemistry"},{"key":"BF01869137_CR19","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1021\/bi00706a022","volume":"13","author":"D.G. Johnson","year":"1974","unstructured":"Johnson, D.G., Thompson, W.J., Williams, R.H. 1974. Regulation of adenylate cyclase from isolated pancreatic islets by prostaglandins and guanosine 5\u2032-triphosphate.Biochemistry 13:1920","journal-title":"Biochemistry"},{"key":"BF01869137_CR20","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1016\/S0021-9258(19)45524-5","volume":"247","author":"G. Krishna","year":"1972","unstructured":"Krishna, G., Harwood, J., Barber, A., Jamieson, G.A. 1972. Requirement for guanosine triphosphate in the prostaglandin activation of adenylate cyclase of platelet membranes.J. Biol. Chem. 247:2253","journal-title":"J. Biol. Chem."},{"key":"BF01869137_CR21","doi-asserted-by":"crossref","first-page":"3699","DOI":"10.1021\/bi00715a013","volume":"13","author":"A.G. Lee","year":"1974","unstructured":"Lee, A.G., Birdsall, N.J.M., Metcalfe, J.C., Toon, P.A., Warren, G.B. 1974. Clusters in lipid bilayers and the interpretation of thermal effects in biological membranes.Biochemistry 13:3699","journal-title":"Biochemistry"},{"key":"BF01869137_CR22","doi-asserted-by":"crossref","first-page":"6119","DOI":"10.1016\/S0021-9258(19)42228-X","volume":"249","author":"R.J. Lefkowitz","year":"1974","unstructured":"Lefkowitz, R.J. 1974. Stimulation of catecholamine-sensitive adenylate cyclase by 5\u2032-guanylylimidodiphosphate.J. Biol. Chem. 249:6119","journal-title":"J. Biol. Chem."},{"key":"BF01869137_CR23","doi-asserted-by":"crossref","first-page":"4418","DOI":"10.1016\/S0021-9258(19)41318-5","volume":"250","author":"R.J. Lefkowitz","year":"1975","unstructured":"Lefkowitz, R.J., Caron, M.G. 1975. Characteristics of 5\u2032-guanylylimidodiphosphate-activated adenylate cyclase.J. Biol. Chem. 250:4418","journal-title":"J. Biol. Chem."},{"key":"BF01869137_CR24","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1016\/0006-291X(72)90866-2","volume":"48","author":"F. Leray","year":"1972","unstructured":"Leray, F., Chambaut, A.-M., Hanoune, J. 1972. Adenylate cyclase activity of rat-liver plasma membranes. Hormonal stimulations and effect of adrenalectomy.Biochem. Biophys. Res. Commun. 48:1385","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"BF01869137_CR25","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1073\/pnas.70.8.2271","volume":"70","author":"C.D. Linden","year":"1973","unstructured":"Linden, C.D., Wright, K.L., McConnell, H.M., Fox, C.F. 1973. Lateral phase separations in membrane lipids and the mechanism of sugar transport inEscherichia coli.Proc. Nat. Acad. Sci. USA 70:2271","journal-title":"Proc. Nat. Acad. Sci. USA"},{"key":"BF01869137_CR26","doi-asserted-by":"crossref","first-page":"3087","DOI":"10.1073\/pnas.71.8.3087","volume":"71","author":"C. Londos","year":"1974","unstructured":"Londos, C., Salomon, Y., Lin, M.C., Harwood, J.P., Schramm, M., Wolff, J., Rodbell, M. 1974. 5\u2032-Guanylylimidodiphosphate-A potent activator of adenylate cyclase systems in eukaryotic cells.Proc. Nat. Acad. Sci. USA 71:3087","journal-title":"Proc. Nat. Acad. Sci. USA"},{"key":"BF01869137_CR27","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","author":"O.H. Lowry","year":"1951","unstructured":"Lowry, O.H., Rosebrough, N.J., Farr, A.L., Randall, R.J. 1951. Protein measurement with the Folin-phenol reagent.J. Biol. Chem. 193:265","journal-title":"J. Biol. Chem."},{"key":"BF01869137_CR28","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1073\/pnas.72.5.1945","volume":"72","author":"C. Mukherjee","year":"1975","unstructured":"Mukherjee, C., Caron, M., Lefkowitz, R.J. 1975. Catecholamine-induced subsensitivity of adenylate cyclase associated with loss of \u03b2-adrenergic receptor binding sites.Proc. Nat. Acad. Sci. USA 72:1945","journal-title":"Proc. Nat. Acad. Sci. USA"},{"key":"BF01869137_CR29","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/S0021-9258(19)41866-8","volume":"250","author":"T. Pfeuffer","year":"1975","unstructured":"Pfeuffer, T., Helmreich, E.J.M. 1975. Activation of pigeon erythrocyte membrane adenylate cyclase of guanylnucleotide analogues and separation of a nucleotide binding protein.J. Biol. Chem. 250:867","journal-title":"J. Biol. Chem."},{"key":"BF01869137_CR30","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1038\/247438a0","volume":"247","author":"M-m Poo","year":"1974","unstructured":"Poo, M-m, Cone, R. 1974. Lateral diffusion of rhodopsin in the photo-receptor membrane.Nature 247:438","journal-title":"Nature"},{"key":"BF01869137_CR31","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0003-2697(71)90128-X","volume":"43","author":"J. Ramachandran","year":"1971","unstructured":"Ramachandran, J. 1971. A new simple method for separation of adenosine 3\u2032, 5\u2032-cyclic monophosphate from other nucleotides and its use in the assay of adenyl cyclase.Anal. Biochem. 43:227","journal-title":"Anal. Biochem."},{"key":"BF01869137_CR32","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1016\/S0021-9258(18)62390-7","volume":"246","author":"M. Rodbell","year":"1971","unstructured":"Rodbell, M., Birnbaumer, L., Pohl, S.L., Krans, H.M. 1971. The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver.J. Biol. Chem. 246:1877","journal-title":"J. Biol. Chem."},{"key":"BF01869137_CR33","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0021-9258(19)43090-1","volume":"249","author":"M. Rodbell","year":"1974","unstructured":"Rodbell, M., Lin, M.C., Salomon, Y. 1974. Evidence for interdependent action of glucagon and nucleotides on the hepatic adenylate cyclase system.J. Biol. Chem. 249:59","journal-title":"J. Biol. Chem."},{"key":"BF01869137_CR34","doi-asserted-by":"crossref","first-page":"5360","DOI":"10.1021\/bi00750a020","volume":"12","author":"E. Sackmann","year":"1973","unstructured":"Sackmann, E., Trauble, H., Galla, H.-J., Overath, P. 1973. Lateral diffusion protein mobility, and phase transitions inEscherichia coli membrane. A spin label study.Biochemistry 12: 5360","journal-title":"Biochemistry"},{"key":"BF01869137_CR35","doi-asserted-by":"crossref","first-page":"4239","DOI":"10.1016\/S0021-9258(19)41409-9","volume":"250","author":"Y. Salomon","year":"1975","unstructured":"Salomon, Y., Lin, M.C., Londos, C., Rendell, M., Rodbell, M. 1975. The hepatic adenylate cyclase system. I. Evidence for transition states and structural requirements for guanine nucleotides.J. Biol. Chem. 250:4239","journal-title":"J. Biol. Chem."},{"key":"BF01869137_CR36","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1073\/pnas.69.8.2056","volume":"69","author":"C.J. Scandella","year":"1972","unstructured":"Scandella, C.J., Devaux, P., McConnell, H.M. 1972. Rapid lateral diffusion of phospholipids in rabbit saroplasmic reticulum.Proc. Nat. Acad. Sci. USA 69:2056","journal-title":"Proc. Nat. Acad. Sci. USA"},{"key":"BF01869137_CR37","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1016\/S0021-9258(19)41707-9","volume":"250","author":"M. Schramm","year":"1975","unstructured":"Schramm, M., Rodbell, M. 1975. A persistant active state of the adenylate cyclase system produced by the combined actions of isoproterenol and guanylylimidodiphosphate in frog erythrocyte membranes.J. Biol. Chem. 250:2232","journal-title":"J. Biol. Chem."},{"key":"BF01869137_CR38","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1021\/bi00736a026","volume":"12","author":"E.J. Shimshick","year":"1973","unstructured":"Shimshick, E.J., McConnell, H.M. 1973. Lateral phase separation in phospholipid membranes.Biochemistry 12:2351","journal-title":"Biochemistry"},{"key":"BF01869137_CR39","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0303-7207(74)90002-1","volume":"1","author":"M.I. Siegel","year":"1974","unstructured":"Siegel, M.I., Cuatrecasas, P. 1974. Epinephrine stimulation of fat cell adenylate cyclase: Regulation by guanosine-5\u2032-triphosphate and magnesium ion.Molec. Cell. Endocrinol. 1:89","journal-title":"Molec. Cell. Endocrinol."},{"key":"BF01869137_CR40","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1146\/annurev.bi.43.070174.004105","volume":"43","author":"S.J. Singer","year":"1974","unstructured":"Singer, S.J. 1974. The molecular organization of membranes.Annu. Rev. Biochem. 43:805","journal-title":"Annu. Rev. Biochem."},{"key":"BF01869137_CR41","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1126\/science.175.4023.720","volume":"175","author":"S.J. Singer","year":"1972","unstructured":"Singer, S.J., Nicolson, G.L. 1972. The fluid mosaic model of the structure of cell membranes.Science 175:720","journal-title":"Science"},{"key":"BF01869137_CR42","doi-asserted-by":"crossref","first-page":"7630","DOI":"10.1016\/S0021-9258(19)81284-X","volume":"249","author":"A.M. Spiegel","year":"1974","unstructured":"Spiegel, A.M., Aurbach, G.D. 1974. Binding of 5\u2032-guanylylimidodiphosphate to turkey erythrocyte membranes and effects on \u03b2-adrenergic-activated adenylate cyclase.J. Biol. Chem. 249:7630","journal-title":"J. Biol. Chem."},{"key":"BF01869137_CR43","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/0005-2787(68)90205-0","volume":"155","author":"R.H. Symons","year":"1968","unstructured":"Symons, R.H. 1968. Modified procedure for the synthesis of32P-labeled ribonucleoside 5\u2032-monophosphate of high specific activity.Biochim. Biophys. Acta 155:609","journal-title":"Biochim. Biophys. Acta"},{"key":"BF01869137_CR44","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.1073\/pnas.71.7.2684","volume":"71","author":"T.Y. Tsong","year":"1974","unstructured":"Tsong, T.Y. 1974. Kinetics of the crystalline-liquid crystalline phase transitions of dimyristoyll-\u03b1-lecithin bilayers.Proc. Nat. Acad. Sci. USA 71:2684","journal-title":"Proc. Nat. Acad. Sci. USA"},{"key":"BF01869137_CR45","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/0003-2697(71)90156-4","volume":"41","author":"A.A. White","year":"1971","unstructured":"White, A.A., Zenser, T.V. 1971. Separation of cyclic 3\u2032-5\u2032-nucleoside monophosphate from other nucleotides on aluminum oxide columns-Application to the assay of adenyl cyclase and guanyl cyclase.Anal. Biochem. 41:372","journal-title":"Anal. Biochem."},{"key":"BF01869137_CR46","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/S0021-9258(19)44480-3","volume":"248","author":"J. Wolff","year":"1973","unstructured":"Wolff, J., Cook, G.H. 1973. Activation of thyroid membrane adenylate cyclase by purine nucleotides.J. Biol. Chem. 248:350","journal-title":"J. Biol. Chem."},{"key":"BF01869137_CR47","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1021\/bi00675a032","volume":"14","author":"S. Wu","year":"1975","unstructured":"Wu, S., McConnell, H. 1975. Phase separations in phospholipid membranes.Biochemistry 14:847","journal-title":"Biochemistry"}],"container-title":["The Journal of Membrane Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01869137.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01869137\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01869137","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T20:51:17Z","timestamp":1626123077000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01869137"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,12]]},"references-count":47,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1976,12]]}},"alternative-id":["BF01869137"],"URL":"https:\/\/doi.org\/10.1007\/bf01869137","relation":{},"ISSN":["0022-2631","1432-1424"],"issn-type":[{"value":"0022-2631","type":"print"},{"value":"1432-1424","type":"electronic"}],"subject":[],"published":{"date-parts":[[1976,12]]}}}