{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T22:29:26Z","timestamp":1757543366807},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1988,2,1]],"date-time":"1988-02-01T00:00:00Z","timestamp":570672000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experientia"],"published-print":{"date-parts":[[1988,2]]},"DOI":"10.1007\/bf01952198","type":"journal-article","created":{"date-parts":[[2005,8,1]],"date-time":"2005-08-01T23:27:52Z","timestamp":1122938872000},"page":"142-145","source":"Crossref","is-referenced-by-count":15,"title":["Human platelet 5-hydroxytryptamine receptors: Binding of [3H]-lysergic acid diethylamide (LSD). Effects of chronic neuroleptic and antidepressant drug administration"],"prefix":"10.1007","volume":"44","author":[{"given":"D. G.","family":"Grahame-Smith","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. P.","family":"Geaney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Schachter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. M.","family":"Elliott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF01952198_CR1","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/BF00175205","volume":"89","author":"I. M. Anderson","year":"1986","unstructured":"Anderson, I. M., and Cowen, P. J., Clomipramine enhances prolactin and growth hormone responses tol-tryptophan. Psychopharmacology89 (1986) 131\u2013133.","journal-title":"Psychopharmacology"},{"key":"BF01952198_CR2","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/0006-8993(75)90234-6","volume":"94","author":"J. P. Bennet","year":"1975","unstructured":"Bennet, J. P., and Snyder, S. H., Stereospecific binding ofd-lysergic acid diethylamide (LSD) to brain membranes: relationship to serotonin receptors. Brain Res.94 (1975) 523.","journal-title":"Brain Res."},{"key":"BF01952198_CR3","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/j.1476-5381.1980.tb10889.x","volume":"69","author":"M. Baldacci","year":"1980","unstructured":"Baldacci, M., Bergel, T. D., Born, G. V. R., and Hickman, M., Increases in aggregation by uptake of 5-hydroxytryptamine with platelets from rabbits treated with chlorpromazine. Br. J. Pharmac. Chemother.69 (1980) 113\u2013118.","journal-title":"Br. J. Pharmac. Chemother."},{"key":"BF01952198_CR4","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.1476-5381.1975.tb07338.x","volume":"53","author":"D. J. Boullin","year":"1975","unstructured":"Boullin, D. J., Grahame-Smith, D. G., Grimes, R. P. J., and Woods, H. F., Inhibition of hydroxytryptamine induced human blood platelet aggregation by chlorpromazine and its metabolites. Br. J. Pharmac. Chemother.53 (1975) 121\u2013125.","journal-title":"Br. J. Pharmac. Chemother."},{"key":"BF01952198_CR5","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1365-2125.1975.tb00468.x","volume":"2","author":"D. J. Boullin","year":"1975","unstructured":"Boullin, D. J., Woods, H. F., Grimes, R. P. J., Grahame-Smith, D. G., Wiles, D., Gelder, M. G., and Kolakowska, T., Increased platelet aggregation responses to 5-hydroxytryptamine in patients taking chlorpromazine. Br. J. clin. Pharmac.2 (1975) 29\u201335.","journal-title":"Br. J. clin. Pharmac."},{"key":"BF01952198_CR6","volume-title":"Platelets: a Multi-disciplinary Approach","author":"D. J. Boullin","year":"1978","unstructured":"Boullin, D. J., Orr, M. W., and Peters, J. R., The platelet as a model for investigating clinical efficacy of centrally acting drugs: relations between platelet aggregation and clinical condition in schizophrenics treated with chlorpromazine, in: Platelets: a Multi-disciplinary Approach. Eds S. E. de Gaetano and S. Gorathine. Raven Press, New York 1978."},{"key":"BF01952198_CR7","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1111\/j.1365-2125.1978.tb00881.x","volume":"6","author":"D. J. Boullin","year":"1978","unstructured":"Boullin, D. J., Knox, J. M., Peters, J., and Orr, M., Platelet aggregation and chlorpromazine therapy. Br. J. clin. Pharmac.6 (1978) 538\u2013540.","journal-title":"Br. J. clin. Pharmac."},{"key":"BF01952198_CR8","unstructured":"Cowen, P. J., and Anderson, I. M., in: Recent advances in the biology of depression. Eds. J. F. W. Deakin and H. Freeman. Royal College of Psychiatrists, special publication, 1986."},{"key":"BF01952198_CR9","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1001\/archpsyc.1986.01800010063008","volume":"43","author":"P. J. Cowen","year":"1986","unstructured":"Cowen, P. J., Geaney, D. P., Schacter, M., Green, A. R., and Elliott, M. J., Desipramine treatment in normal subjects effects on neuroendocrine response to tryptophan and on platelet serotonin (5-HT)-related receptors. Archs gen. Psychiat.43 (1986) 61\u201367.","journal-title":"Archs gen. Psychiat."},{"key":"BF01952198_CR10","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0014-2999(82)90555-6","volume":"82","author":"A. J. Cross","year":"1982","unstructured":"Cross, A. J., Interactions of [3H]-LSD with serotonin receptors in human brain. Eur. J. Pharmac.82 (1982) 77.","journal-title":"Eur. J. Pharmac."},{"key":"BF01952198_CR11","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1476-5381.1981.tb16784.x","volume":"73","author":"D. Dawbarn","year":"1981","unstructured":"Dawbarn, D., Long, S. K., and Pycock, C. J., Increased central 5-hydroxytryptamine receptor mechanisms in rats after chronic neuroleptic treatment. Br. J. Pharmac. Chemother.73 (1981) 149\u2013156.","journal-title":"Br. J. Pharmac. Chemother."},{"key":"BF01952198_CR12","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0014-2999(84)90515-6","volume":"97","author":"D. P. Geaney","year":"1984","unstructured":"Geaney, D. P., Schacter, M., Elliott, J. M., and Grahame-Smith, D. G., Characterization of [3H]-Lysergic acid diethylamide binding to a 5-hydroxytryptamine receptor on human platelet membranes. Eur. J. Pharmac.97 (1984) 87\u201393.","journal-title":"Eur. J. Pharmac."},{"key":"BF01952198_CR13","first-page":"398","volume":"90","author":"P. W. Glue","year":"1986","unstructured":"Glue, P. W., Cowen, P. J., Nutt, D. J., Kolakowska, T., and Grahame-Smith, D. G., The effect of Lithium on 5-HT mediated neuroendocrine responses and platelet 5-HT receptors. Psychopharmacology90 (1986) 398\u2013402.","journal-title":"Psychopharmacology"},{"key":"BF01952198_CR14","first-page":"77","volume-title":"Enzymes and Neurotransmitters in Mental Disease","author":"A. Hefez","year":"1980","unstructured":"Hefez, A., Oppenheim, B., and Youdim, M. B. H., Human platelet aggregation response to serotonin as an index of efficacy of chlorpromazine, in: Enzymes and Neurotransmitters in Mental Disease, pp. 77\u201393. Eds E. Usdin, T. L. Sourkes and M. B. H. Youdim. John Wiley, New York 1980."},{"key":"BF01952198_CR15","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/j.1365-2125.1981.tb00531.x","volume":"11","author":"J. M. Knox","year":"1981","unstructured":"Knox, J. M., Orr, M. W., Allen, R., Gelder, M. G., and Grahame-Smith, D. G., The reliability of 5-hydroxytryptamine reduced platelet aggregation responses in schizophrenic patients with neuroleptic drugs. Br. J. clin. Pharmac.11 (1981) 261\u2013263.","journal-title":"Br. J. clin. Pharmac."},{"key":"BF01952198_CR16","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1016\/0024-3205(79)90233-9","volume":"24","author":"A. Laubscher","year":"1979","unstructured":"Laubscher, A., and Pletscher, A., Shape change and uptake of 5-hydroxytryptamine in human blood platelets: actions of neuropsychotropic drugs. Life Sci.24 (1979) 1833.","journal-title":"Life Sci."},{"key":"BF01952198_CR17","first-page":"385","volume":"216","author":"A. Laubscher","year":"1981","unstructured":"Laubscher, A., Pletscher, A., and Noll, H., Interaction ofd-LSD with blood platelets of rabbits: shape, change and specific binding. J. Pharmac. exp. Ther.216 (1981) 385.","journal-title":"J. Pharmac. exp. Ther."},{"key":"BF01952198_CR18","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0014-2999(83)90401-6","volume":"88","author":"J. E. Leysen","year":"1983","unstructured":"Leysen, J. E., Commeren, W., and de Clerck, F., Demonstration of S2-receptor binding sites in cat platelets using [3H]-ketanserin. Eur. J. Pharmac.88 (1983) 125\u2013130.","journal-title":"Eur. J. Pharmac."},{"key":"BF01952198_CR19","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/213035a0","volume":"213","author":"D. C. B. Mills","year":"1967","unstructured":"Mills, D. C. B., and Roberts, G. C. K., Membrane active drugs and the aggregation of human blood platelets. Nature213 (1967) 35\u201338.","journal-title":"Nature"},{"key":"BF01952198_CR20","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1111\/j.1365-2125.1976.tb00648.x","volume":"3","author":"M. W. Orr","year":"1976","unstructured":"Orr, M. W., and Boullin, D. J., The relationship between changes in 5-HT induced platelet aggregation and the clinical state in patients treated with fluphenazine. Br. J. clin. Pharmac.3 (1976) 925\u2013928.","journal-title":"Br. J. clin. Pharmac."},{"key":"BF01952198_CR21","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1365-2125.1981.tb00530.x","volume":"11","author":"M. W. Orr","year":"1981","unstructured":"Orr, M. W., Knox, J. M., Allen, R., Gelder, M. G., and Grahame-Smith, D. G., The effects of neuroleptic drugs on 5-hydroxytryptamine induced platelet aggregation in schizophrenic patients. Br. J. clin. Pharmac.11 (1981) 255\u2013259.","journal-title":"Br. J. clin. Pharmac."},{"key":"BF01952198_CR22","first-page":"687","volume":"16","author":"S. J. Peroutka","year":"1979","unstructured":"Peroutka, S. J., and Snyder, S. H., Multiple serotonin receptors differential binding of [3H]-5-hydroxytryptamine, [3H]-lysergic acid diethylamide and [3H]-spiroperidol. Molec. Pharmac.16 (1979) 687\u2013698.","journal-title":"Molec. Pharmac."},{"key":"BF01952198_CR23","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1126\/science.6251550","volume":"210","author":"S. J. Peroutka","year":"1980","unstructured":"Peroutka, S. J., and Snyder, S. H., Long-term antidepressant treatment decreases spiroperidol-labelled serotonin receptor treatment. Science210 (1980) 88\u201390.","journal-title":"Science"},{"key":"BF01952198_CR24","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/0014-2999(80)90522-1","volume":"68","author":"J. R. Peters","year":"1980","unstructured":"Peters, J. R., and Grahame-Smith, D. G., Human platelet 5-HT receptors: characterisation and functional association. Eur. J. Pharmac.68 (1980) 243.","journal-title":"Eur. J. Pharmac."},{"key":"BF01952198_CR25","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.1365-2125.1985.tb02670.x","volume":"19","author":"M. Schacter","year":"1985","unstructured":"Schacter, M., Geaney, D. P., Grahame-Smith, D. G., Cowen, P., and Elliott, J. M., Increased platelet membrane [3H]-LSD binding in patients on chronic neuroleptic treatment. Br. J. clin. Pharmac.19 (1985) 453\u2013457.","journal-title":"Br. J. clin. Pharmac."}],"container-title":["Experientia"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01952198.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01952198\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01952198","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,13]],"date-time":"2019-05-13T13:14:18Z","timestamp":1557753258000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01952198"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,2]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1988,2]]}},"alternative-id":["BF01952198"],"URL":"https:\/\/doi.org\/10.1007\/bf01952198","relation":{},"ISSN":["0014-4754","1420-9071"],"issn-type":[{"value":"0014-4754","type":"print"},{"value":"1420-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,2]]}}}