{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T14:47:19Z","timestamp":1778597239294,"version":"3.51.4"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[1993,8,1]],"date-time":"1993-08-01T00:00:00Z","timestamp":744163200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Toxicol"],"published-print":{"date-parts":[[1993,8]]},"DOI":"10.1007\/bf01969271","type":"journal-article","created":{"date-parts":[[2005,7,30]],"date-time":"2005-07-30T13:52:12Z","timestamp":1122731532000},"page":"573-579","source":"Crossref","is-referenced-by-count":11,"title":["Fluoride toxicity: A biochemical and scanning electron microscopic study of enamel surface of rabbit teeth"],"prefix":"10.1007","volume":"67","author":[{"given":"A. K.","family":"Susheela","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Bhatnagar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF01969271_CR1","first-page":"159","volume":"32","author":"J Almano","year":"1982","unstructured":"Almano J, Cutress TW (1982) An epidemiological index of developmental defects on dental enamel. (DDE Index) Int Dent J 32: 159","journal-title":"(DDE Index) Int Dent J"},{"key":"BF01969271_CR2","first-page":"166","volume":"21","author":"Mansson B Angmar","year":"1987","unstructured":"Angmar Mansson B, Whitford GM (1987) Identification of the fluoride sensitive stages of enamel development. Caries Res 21: 166","journal-title":"Caries Res"},{"key":"BF01969271_CR3","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1159\/000260215","volume":"10","author":"BKB Berkavitz","year":"1976","unstructured":"Berkavitz BKB, Head PF (1976) The effect of fluoride on iron, calcium, phosphorus distribution in the rat incisor. Caries Res 10: 337\u2013357","journal-title":"Caries Res"},{"key":"BF01969271_CR4","first-page":"230","volume-title":"Fluorides and human health","author":"BR Bhussry","year":"1970","unstructured":"Bhussry BR (1970) Chronic toxic effects on enamel organs. In: Fluorides and human health. WHO, Geneva, pp 230\u2013238"},{"key":"BF01969271_CR5","first-page":"117","volume":"32","author":"TW Cutress","year":"1982","unstructured":"Cutress TW, Suckling TW (1982) The assessment of non-carious caries defects of enamel. Int Dent J 32: 117\u2013122","journal-title":"Int Dent J"},{"issue":"9","key":"BF01969271_CR6","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/0003-9969(84)90171-7","volume":"29","author":"PK Denbesten","year":"1984","unstructured":"Denbesten PK, Crenshaw MA (1984) The effect of chronic high fluoride levels on forming enamel in the rat. Arch Oral Biol 29 [9]: 675\u2013679","journal-title":"Arch Oral Biol"},{"key":"BF01969271_CR7","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1159\/000260157","volume":"9","author":"O Fejerskov","year":"1975","unstructured":"Fejerskov O, Silverstone LM, Mclsen B, Moller IJ (1975) Histological features of fluorosed human dental enamel. Caries Res 9: 190\u2013210","journal-title":"Caries Res"},{"key":"BF01969271_CR8","first-page":"510","volume":"85","author":"O Fejerskov","year":"1977","unstructured":"Fejerskov O, Thylstrup A, Larsen JM (1977) Clinical and structural and possible pathogenic mechanisms of dental fluorosis. Scand J Dent Res 85: 510\u2013534","journal-title":"Scand J Dent Res"},{"key":"BF01969271_CR9","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0021-9258(18)84756-1","volume":"66","author":"CH Fiske","year":"1925","unstructured":"Fiske CH, Subba Rao (1925) The coloriometric determination of phosphorus. J Biol Chem 66: 375\u2013401","journal-title":"J Biol Chem"},{"key":"BF01969271_CR10","doi-asserted-by":"crossref","first-page":"239","DOI":"10.2330\/joralbiosci1965.13.239","volume":"13","author":"K Hasegawa","year":"1971","unstructured":"Hasegawa K (1971) Studies on formative disturbances of enamel in experimental chronic fluorosis. Jpn J Oral Biol 13: 239\u2013254","journal-title":"Jpn J Oral Biol"},{"key":"BF01969271_CR11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5357\/koubyou.24.1","volume":"24","author":"T Ishiki","year":"1957","unstructured":"Ishiki T (1957) The histologic changes in the tooth and the salivary gland of the rat in the experimental fluorosis. J Jpn Stomatol Soc 24: 1\u201318","journal-title":"J Jpn Stomatol Soc"},{"issue":"3","key":"BF01969271_CR12","first-page":"255","volume":"VI","author":"M Jha","year":"1984","unstructured":"Jha M, Susheela AK (1984) Scanning electron microscopic and electron microprobe X-ray analysis of cortical bone of fluoride treated rabbits. Int J Tissue React VI(3): 255\u2013261","journal-title":"Int J Tissue React"},{"key":"BF01969271_CR13","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0003-9969(70)90046-4","volume":"15","author":"BJ Kruger","year":"1970","unstructured":"Kruger BJ (1970) The effect of different levels of fluoride on the ultrastructure of ameloblasts in the rats. Arch Oral Biol 15: 109\u2013114","journal-title":"Arch Oral Biol"},{"key":"BF01969271_CR14","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1600-0714.1986.tb00583.x","volume":"15","author":"NA Lange","year":"1986","unstructured":"Lange NA, Lendskog S, Ekstrand J et al. (1986) Fluoride induce cystic changes in enamel organ of the rat molar. J Oral Pathol 15: 87\u201392","journal-title":"J Oral Pathol"},{"key":"BF01969271_CR15","first-page":"211","volume":"86","author":"H Mornstad","year":"1978","unstructured":"Mornstad H, Hammarstrom L (1978) Morphological changes in the rat enamel organ following a single intraperitoneal injection of sodium fluoride. Scand J Dent Res 86: 211\u2013220","journal-title":"Scand J Dent Res"},{"key":"BF01969271_CR16","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1002\/ar.1091830207","volume":"183","author":"A Neiman","year":"1975","unstructured":"Neiman A, Eisenmann R (1975) The effect of strontium cobalt and fluoride in rat incisor enamel formation. Anat Res 183: 303\u2013322","journal-title":"Anat Res"},{"key":"BF01969271_CR17","first-page":"185","volume":"94","author":"AL Nordland","year":"1986","unstructured":"Nordland AL and Lendskog S (1986) Scanning electron microscopy of fluoride induced disturbances in enamel surface of rat molar. Scand J Dent Res 94: 185\u2013192","journal-title":"Scand J Dent Res"},{"key":"BF01969271_CR18","first-page":"1","volume":"113","author":"HE Parker","year":"1963","unstructured":"Parker HE (1963) Magnesium, calcium and zinc in animal nutrition. Atom Absorpt News 113: 1","journal-title":"Atom Absorpt News"},{"key":"BF01969271_CR19","first-page":"123","volume":"32","author":"JJ Pindborg","year":"1982","unstructured":"Pindborg JJ (1982) Aetiology of development defects not related to fluorosis. Int Dent J 32: 123\u2013135","journal-title":"Int Dent J"},{"key":"BF01969271_CR20","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/BF02546229","volume":"18","author":"H Shinoda","year":"1975","unstructured":"Shinoda H (1975) Effects of long term administration of fluoride on physio-chemical properties of the rat incisor enamel. Calcif Tissue Res 18: 91\u2013100","journal-title":"Calcif Tissue Res"},{"key":"BF01969271_CR21","first-page":"259","volume-title":"Mechanisms of tooth enamel formation","author":"H Shinoda","year":"1983","unstructured":"Shinoda H (1983) Effects of long term administration of fluoride on the enamel formation in rat. In: Saga S (ed) Mechanisms of tooth enamel formation. Quintesence Publishing Co, Tokyo, pp 259\u2013272"},{"key":"BF01969271_CR22","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1021\/ac60259a017","volume":"40","author":"L Singer","year":"1968","unstructured":"Singer L, Armstrong WD (1968) Determination of fluoride in bone with fluoride electrode. Anal Chem 40: 613\u2013614","journal-title":"Anal Chem"},{"key":"BF01969271_CR23","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0300-5712(78)90004-0","volume":"6","author":"BW Small","year":"1978","unstructured":"Small BW, Murry JJ (1978) Enamel opacities prevalence, classification and aetiological considerations. J Dent Res 6: 33\u201342","journal-title":"J Dent Res"},{"key":"BF01969271_CR24","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1177\/00220345320120010501","volume":"12","author":"MC Smith","year":"1932","unstructured":"Smith MC, Lantz E, Smith MV (1932) The causes of mottled enamel. J Dent Res 12: 149\u2013159","journal-title":"J Dent Res"},{"key":"BF01969271_CR25","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/0014-4800(90)90025-9","volume":"53","author":"AK Susheela","year":"1990","unstructured":"Susheela AK, Kharb P (1990) Aortic calcification in chronic fluoride poisoning: Biochemical and Electron microscopic evidence. Exp Mol Pathol 53: 72\u201380","journal-title":"Exp Mol Pathol"},{"key":"BF01969271_CR26","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1007\/BF00332496","volume":"62","author":"AK Susheela","year":"1988","unstructured":"Susheela AK, Sharma K (1988) Fluoride induced changes in tooth glycosaminoglycans an in vivo study in the rabbit. Arch Toxicol 62: 328\u2013330","journal-title":"Arch Toxicol"},{"issue":"10","key":"BF01969271_CR27","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/0003-9969(88)90011-8","volume":"33","author":"AK Susheela","year":"1988","unstructured":"Susheela AK, Sharma K, Rajan BP, Gnanasundaram N (1988) The status of sulphated isomers of glycosaminoglycans in fluorosed human teeth. Arch Oral Biol 33 [10]: 765\u2013767","journal-title":"Arch Oral Biol"},{"key":"BF01969271_CR28","first-page":"105","volume":"87","author":"A Thylstrup","year":"1979","unstructured":"Thylstrup A, Ferjerskov O (1979) A scanning electron microscopic and microradiographic study of pits in fluorosed human enamel. Scand J Dent Res 87: 105\u2013114","journal-title":"Scand J Dent Res"},{"key":"BF01969271_CR29","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0003-9969(74)90212-X","volume":"19","author":"RE Walton","year":"1974","unstructured":"Walton RE, Eisenmann DR (1974) Ultrastructural examination of various stages of amelogenesis in rat following parenteral fluoride administration. Arch Oral Biol 19: 171\u2013182","journal-title":"Arch Oral Biol"},{"key":"BF01969271_CR30","first-page":"104","volume-title":"Fluorides and human health","author":"SM Weidmann","year":"1970","unstructured":"Weidmann SM, Weatherell JA (1970) Distribution in hard tissue. In: Fluorides and human health. WHO, Geneva, pp 104\u2013128"},{"key":"BF01969271_CR31","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1007\/BF02062608","volume":"7","author":"VC West","year":"1971","unstructured":"West VC (1971) Observation on phase transformation of a precepitative calcium phosphate. Calcif Tissue Res 7: 212\u2013219","journal-title":"Calcif Tissue Res"},{"key":"BF01969271_CR32","first-page":"481","volume":"88","author":"J Westergaard","year":"1980","unstructured":"Westergaard J (1980) Structural changes induced by tetracycline in secretory ameloblasts in young rats. Scand J Dent Res 88: 481\u2013495","journal-title":"Scand J Dent Res"}],"container-title":["Archives of Toxicology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01969271.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01969271\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01969271","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,14]],"date-time":"2021-07-14T08:05:03Z","timestamp":1626249903000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01969271"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,8]]},"references-count":32,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1993,8]]}},"alternative-id":["BF01969271"],"URL":"https:\/\/doi.org\/10.1007\/bf01969271","relation":{},"ISSN":["0340-5761","1432-0738"],"issn-type":[{"value":"0340-5761","type":"print"},{"value":"1432-0738","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,8]]}}}