{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T20:24:49Z","timestamp":1780604689362,"version":"3.54.1"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"1-2","license":[{"start":{"date-parts":[[1987,6,1]],"date-time":"1987-06-01T00:00:00Z","timestamp":549504000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Agents and Actions"],"published-print":{"date-parts":[[1987,6]]},"DOI":"10.1007\/bf01974942","type":"journal-article","created":{"date-parts":[[2005,7,31]],"date-time":"2005-07-31T15:41:58Z","timestamp":1122824518000},"page":"195-202","source":"Crossref","is-referenced-by-count":9,"title":["Antagonists of PAF-acether do not suppress thrombin-induced aggregation of ADP-deprived and aspirin-treated human platelets"],"prefix":"10.1007","volume":"21","author":[{"given":"S.","family":"Adnot","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Joseph","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. B.","family":"Vargaftig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF01974942_CR1","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1084\/jem.136.6.1356","volume":"136","author":"J. Benveniste","year":"1972","unstructured":"J. Benveniste, P. M. Henson and C. G. Cochrane,Leukocyte-dependent histamine release from rabbit platelets: the role of IgE, basophils and platelet-activating factor. J. exp. Med.136, 1356\u20131376 (1972).","journal-title":"J. exp. Med."},{"key":"BF01974942_CR2","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1111\/j.2042-7158.1977.tb11293.x","volume":"29","author":"B. B. Vargaftig","year":"1977","unstructured":"B. B. Vargaftig,Carrageenan and thrombin trigger prostaglandin synthetase-independent aggregation of rabbit platelets: inhibition by phospholipase A2 inhibitors. J. Pharm. Pharmacol.29, 222\u2013228 (1977).","journal-title":"J. Pharm. Pharmacol."},{"key":"BF01974942_CR3","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1073\/pnas.75.2.818","volume":"75","author":"E. G. Lapetina","year":"1978","unstructured":"E. G. Lapetina, K. A. Chandrabose and P. Cuatreacasas,Ionophore A23187 and thrombin-induced platelet aggregation: independence from cyclooxygenase products. Proc. Natl. Acad. Sci. USA75, 818\u2013822 (1978).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BF01974942_CR4","first-page":"707","volume":"90","author":"R. M. L. Kinlough-Rathbone","year":"1977","unstructured":"R. M. L. Kinlough-Rathbone, P. A. Packham, H. J. Reimers, J. P. Cazenave and J. F. Mustard,Mechanisms of platelet shape change, aggregation and release induced by collagen, thrombin, or A23187. J. Lab. Clin. Med.90, 707\u2013719 (1977).","journal-title":"J. Lab. Clin. Med."},{"key":"BF01974942_CR5","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1038\/279799a0","volume":"279","author":"M. Chignard","year":"1979","unstructured":"M. Chignard, J. P. Le Couedic, M. Tence, B. B. Vargaftig and J. Benveniste,The role of platelet-activating factor in platelet aggregation. Nature279, 788\u2013800 (1979).","journal-title":"Nature"},{"key":"BF01974942_CR6","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/j.1365-2141.1980.tb05993.x","volume":"46","author":"M. Chignard","year":"1980","unstructured":"M. Chignard, J. P. Le Couedic, M. Tence, B. B. Vargaftig and J. Benveniste,Platelet-activating factor (PAF-acether) secretion from platelets: effects of aggregating agents. Brit. J. Haematol.46, 455\u2013464 (1980).","journal-title":"Brit. J. Haematol."},{"key":"BF01974942_CR7","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1042\/bj2290811","volume":"230","author":"L. Touqui","year":"1985","unstructured":"L. Touqui, M. Hatmi and B. B. Vargaftig,Human platelets stimulated by thrombin produce PAF-acether (1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when the degradating enzyme acetyl hydrolase is blocked. Biochem. J.230, 811\u2013816 (1985).","journal-title":"Biochem. J."},{"key":"BF01974942_CR8","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1016\/0024-3205(83)90049-8","volume":"32","author":"Z. I. Terashita","year":"1983","unstructured":"Z. I. Terashita, S. Tsushima, Y. Yoshioka, H. Nomura, Y. Inada and K. Nishikawa,CV-3988, a specific antagonist of platelet-activating factor. Life Sci.32, 1957\u20131982 (1983).","journal-title":"Life Sci."},{"key":"BF01974942_CR9","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/0090-6980(85)90035-8","volume":"30","author":"K. Burri","year":"1985","unstructured":"K. Burri, B. Barner, J. M. Cassal, P. Hadvary, G. Hirth and K. Muller,PAF: from agonists to antagonists by synthesis. Prostaglandins30, 691 (1985).","journal-title":"Prostaglandins"},{"key":"BF01974942_CR10","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/0090-6980(85)90032-2","volume":"30","author":"P. S\u00e9divy","year":"1985","unstructured":"P. S\u00e9divy, C. G. Caillard, A. Floch, F. Folliard, S. Mondot, C. Robaut and B. Terlain,48740 RP: a specific PAF-acether antagonist. Prostaglandins30, 688 (1985).","journal-title":"Prostaglandins"},{"key":"BF01974942_CR11","doi-asserted-by":"crossref","unstructured":"P. Braquet, GB Patent 8, 418, 424, July 19 (1984).","DOI":"10.1007\/BF03304676"},{"issue":"n\u00b0 1","key":"BF01974942_CR12","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0041-0101(82)90228-8","volume":"20","author":"G. Marlas","year":"1982","unstructured":"G. Marlas,Purification and preliminary structure of a potent platelet aggregating glycoprotein isolated from the venom of Crotalus durissus cascavella. Toxicon20, n\u00b0 1, 289\u2013290 (1982).","journal-title":"Toxicon"},{"key":"BF01974942_CR13","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0014-2999(83)90108-5","volume":"92","author":"B. B. Vargaftig","year":"1983","unstructured":"B. B. Vargaftig, D. Joseph, F. Wal, G. Marlas, M. Chignard and L. G. Chevance,Convulxin-induced activation of intact and of thrombin-degranulated rabbit platelets: specific crossed desensitization with collagen. Eur. J. Pharmac.92, 57\u201368 (1983).","journal-title":"Eur. J. Pharmac."},{"key":"BF01974942_CR14","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1055\/s-0038-1647940","volume":"35","author":"H. J. Reimers","year":"1976","unstructured":"H. J. Reimers, R. L. Kinlough-Rathbone, J. P. Cazenave, A. F. Senyi, J. Hirsh, A. Packham and J. F. Mustard,In vitro and in vivo functions, of thrombin-treated platelets.Thromb. Haemostas. 35, 151\u2013165 (1976).","journal-title":"Thromb. Haemostas."},{"key":"BF01974942_CR15","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1111\/j.1476-5381.1984.tb16216.x","volume":"83","author":"F. Fouque","year":"1984","unstructured":"F. Fouque and B. B. Vargaftig,Triggering by platelet-activating factor and adrenaline of cyclooxygenase-independent platelet aggregation. Br J. Pharmac.83, 625\u2013633 (1984).","journal-title":"Br J. Pharmac."},{"key":"BF01974942_CR16","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/j.1365-2141.1982.tb08489.x","volume":"51","author":"C. Lalau-Keraly","year":"1982","unstructured":"C. Lalau-Keraly and J. Benveniste,Specific desensitization of rabbit platelets by platelet-activating factor (PAF-acether) and derivatives. Br. H. Haematol.,51, 313\u2013322 (1982).","journal-title":"Br. H. Haematol."},{"key":"BF01974942_CR17","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1055\/s-0038-1661245","volume":"53","author":"F. Wal","year":"1985","unstructured":"F. Wal, D. Joseph, L. Touqui and B. B. Vargaftig,PAF-acether may not mediate the third pathway of platelet aggregation since self-desensitization reduces the effects of low thrombin but enhances those of convulxin. Thromb. Haemost.53, 99\u2013104 (1985).","journal-title":"Thromb. Haemost."},{"key":"BF01974942_CR18","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1007\/BF01952560","volume":"40","author":"L. Touqui","year":"1984","unstructured":"L. Touqui, M. Chignard, C. Jacquemin, F. Wal and B. B. Vargaftig,Dissociation between inhibition of phospholipid methylation and production of PAF-acether by rabbit platelets. Experientia,40, 374\u2013377 (1984).","journal-title":"Experientia"},{"key":"BF01974942_CR19","first-page":"61","volume":"14","author":"J. Westwick","year":"1985","unstructured":"J. Westwick, G. Mark and V. V. Kakkar,The role of platelet-activating factor (PAF) in cyclo-oxygenase independent thrombin and collagen-induced platelet activation. J. Pharmacol. (Paris)14, 61 Abst (1985).","journal-title":"J. Pharmacol. (Paris)"},{"key":"BF01974942_CR20","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/0014-5793(83)81066-7","volume":"162","author":"T. J. Hallam","year":"1983","unstructured":"T. J. Hallam, M. C. Scrutton and R. B. Wallis,The role of 1-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (AcGEPC) and palmitoyl-lysophosphatidate in the responses of human blood platelets to collagen and thrombi. FEBS Letters162, 142\u2013146 (1983).","journal-title":"FEBS Letters"},{"key":"BF01974942_CR21","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/0049-3848(83)90402-4","volume":"30","author":"E. Kloprogge","year":"1983","unstructured":"E. Kloprogge, G. H. de Hass, G. Gorter and J. W. N. Akkerman,Stimulus-response coupling in human platelets. Evidence against a role of PAF-Acether in the \u201cThird Pathway\u201d. Thromb. Res.30, 107\u2013112 (1983).","journal-title":"Thromb. Res."},{"key":"BF01974942_CR22","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1749-6632.1981.tb29727.x","volume":"370","author":"B. B. Vargaftig","year":"1981","unstructured":"B. B. Vargaftig, M. Chignard, J. Benveniste, J. Lefort and F. Wal,Background and present status of research on platelet-activating factor (PAF-acether). Ann. N.Y. Acad. Sci.370, 119\u2013137 (1981).","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"BF01974942_CR23","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/B978-0-12-468780-6.50023-8","volume-title":"Ether Lipids: biochemical and biomedical aspects","author":"J. Benveniste","year":"1983","unstructured":"J. Benveniste and B. B. Vargaftig,Platelet activating factor: an, ether lipid with biological activity. In:Ether Lipids: biochemical and biomedical aspects. (Eds. H. K. Mangold and F. Pantolf), Amsterdam, Elsevier 1983, pp. 355\u2013373."}],"container-title":["Agents and Actions"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01974942.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01974942\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01974942","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T13:48:21Z","timestamp":1586353701000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01974942"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,6]]},"references-count":23,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[1987,6]]}},"alternative-id":["BF01974942"],"URL":"https:\/\/doi.org\/10.1007\/bf01974942","relation":{},"ISSN":["0065-4299","1420-908X"],"issn-type":[{"value":"0065-4299","type":"print"},{"value":"1420-908X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,6]]}}}