{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T18:56:54Z","timestamp":1760295414192},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"3-4","license":[{"start":{"date-parts":[[1994,10,1]],"date-time":"1994-10-01T00:00:00Z","timestamp":780969600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Agents and Actions"],"published-print":{"date-parts":[[1994,10]]},"DOI":"10.1007\/bf01983470","type":"journal-article","created":{"date-parts":[[2005,8,3]],"date-time":"2005-08-03T22:05:18Z","timestamp":1123106718000},"page":"86-91","source":"Crossref","is-referenced-by-count":6,"title":["Study of the activation mechanism of adriamycin on rat mast cells"],"prefix":"10.1007","volume":"42","author":[{"given":"M. D.","family":"Est\u00e9vez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. R.","family":"Vieytes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. M.","family":"Botana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF01983470_CR1","series-title":"Cell Biology of the Secretory Process","volume-title":"Mast Cell Secretion","year":"1984","unstructured":"T. W. Martin and D. Lagunoff, Ed.,Mast Cell Secretion. Cell Biology of the Secretory Process, Basel Karger 1984."},{"key":"BF01983470_CR2","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/BF00684855","volume":"29","author":"L. M. Botana","year":"1992","unstructured":"L. M. Botana, E. Arnaez, M. R. Vieytes, A. Alfonso, M. J. Bujan, M. C. Louzao and A. Cabado,Non-immunological release of histamine from rat mast cells elicited by antineoplastic agents. Cancer Chemother. Pharmacol.29, 495\u2013498 (1992).","journal-title":"Cancer Chemother. Pharmacol."},{"key":"BF01983470_CR3","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1007\/BF00685603","volume":"30","author":"L. M. Botana","year":"1992","unstructured":"L. M. Botana, E. Arnaez, M. R. Vieytes, A. Alfonso and M. C. Louzao,Nonimmunological release of histamine from rat mast cells elicited by antineoplastic agents: Effect of drug combinations. Cancer Chemother. Pharmacol.30, 487\u2013490 (1992).","journal-title":"Cancer Chemother. Pharmacol."},{"key":"BF01983470_CR4","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/0006-2952(92)90446-P","volume":"44","author":"E. Arnaez","year":"1992","unstructured":"E. Arnaez, A. Alfonso, M. Estevez, M. R. Vieytes, M. C. Louzao and L. M. Botana,Effect of purification, theophylline and sodium fluoride on histamine release produced by antineoplastic drugs on rat mast cells. A distinctive mechanism of action for carboplatin. Biochem. Pharmacol.44, 533\u2013538 (1992).","journal-title":"Biochem. Pharmacol."},{"key":"BF01983470_CR5","first-page":"142","volume":"49","author":"B. Diamant","year":"1990","unstructured":"B. Diamant,New insights into the mechanisms of histamine release from rat peritoneal mast cells. Chem. Immunol.49, 142\u2013172 (1990).","journal-title":"Chem. Immunol."},{"key":"BF01983470_CR6","first-page":"455","volume":"24","author":"K. F. Bartoli","year":"1989","unstructured":"K. F. Bartoli, G. Decorti, L. Candussio and L. Baldini,Effect of phosphatidylserine on adriamycin uptake and histamine release in rat peritoneal mast cells. Pharmacol. Res.24, 455\u2013456 (1989).","journal-title":"Pharmacol. Res."},{"key":"BF01983470_CR7","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0163-7258(91)90060-Y","volume":"49","author":"T. R. Tritton","year":"1991","unstructured":"T. R. Tritton,Cell Surface Actions of Adriamycin. Pharmacol. Ther.49, 293\u2013309 (1991).","journal-title":"Pharmacol. Ther."},{"key":"BF01983470_CR8","first-page":"1921","volume":"49","author":"G. Decorti","year":"1989","unstructured":"G. Decorti, F. B. Klugmann, L. Candussio, A. Furlani, V. Scarcia and L. Baldini,Uptake of adriamycin by rat and mouse mast cells and correlation with histamine release. Cancer Res.49, 1921\u20131926 (1989).","journal-title":"Cancer Res."},{"key":"BF01983470_CR9","doi-asserted-by":"crossref","first-page":"3523","DOI":"10.1016\/0006-2952(88)90706-X","volume":"37","author":"N. Eleno","year":"1988","unstructured":"N. Eleno, L. M. Botana and J. Espinosa,Veratridine elicits histamine release and promotes calcium uptake in mast cells. Biochem. Pharmacol.37, 3523\u20133525 (1988).","journal-title":"Biochem. Pharmacol."},{"key":"BF01983470_CR10","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/0076-6879(71)17150-9","volume":"XVII","author":"P. A. Shore","year":"1971","unstructured":"P. A. Shore,Fluorometric assay of histamine. Meth. Enz.XVII, 842\u2013845 (1971).","journal-title":"Meth. Enz."},{"key":"BF01983470_CR11","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/0006-2952(94)90194-5","volume":"47","author":"M. D. Est\u00e9vez","year":"1994","unstructured":"M. D. Est\u00e9vez, M. R. Vieytes, M. C. Louzao and L. M. Botana,Effect of okadaic acid on immunologic and non-immunologic histamine release in rat mast cells. Biochem. Pharmacol.47, 591\u2013593 (1994).","journal-title":"Biochem. Pharmacol."},{"key":"BF01983470_CR12","first-page":"449","volume":"42","author":"L. M. Botana","year":"1986","unstructured":"L. M. Botana, J. Espinosa and O. M. P. Fernandez, [Response of pleural and peritoneal mastocyte populations in the rat to agents with different mechanisms of action]. Rev. Esp. Fisiol.42, 449\u2013453 (1986).","journal-title":"Rev. Esp. Fisiol."},{"key":"BF01983470_CR13","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1016\/0006-2952(86)90724-0","volume":"35","author":"G. Decorti","year":"1986","unstructured":"G. Decorti, K. F. Bartoli, L. Candussio and L. Baldini,Characterization of histamine secretion induced by anthracyclines in rat peritoneal mast cells. Biochem. Pharmacol.35, 1939\u20131942 (1986).","journal-title":"Biochem. Pharmacol."},{"key":"BF01983470_CR14","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0014-5793(90)80983-P","volume":"268","author":"T. Johansen","year":"1990","unstructured":"T. Johansen,Estimation of adenosine triphosphate utilization of rat mast cells during and after anaphylactic histamine secretion. FEBS Lett.268, 103\u2013106 (1990).","journal-title":"FEBS Lett."},{"key":"BF01983470_CR15","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1083\/jcb.105.6.2745","volume":"105","author":"S. Cockcroft","year":"1987","unstructured":"S. Cockcroft, T. W. Howell and B. D. Gomperts,Two G-proteins act in series to control stimulus-secretion coupling in mast cells: use of neomycin to distinguish between G-proteins controlling polyphosphoinositide phosphodiesterase and exocytosis. J. Cell Biol.105, 2745\u20132750 (1987).","journal-title":"J. Cell Biol."},{"key":"BF01983470_CR16","doi-asserted-by":"crossref","first-page":"3927","DOI":"10.4049\/jimmunol.138.11.3927","volume":"138","author":"H. Saito","year":"1987","unstructured":"H. Saito, F. Okajima, T. F. Molski, R. I. Shaafi, M. Ui and T. Ishizaka,Effects of ADP-ribosylation of GTP-binding protein by pertussis toxin on immunoglobulin E-dependent and-independent histamine release from mast cells and basophils. J. Immunol.138, 3927\u20133934 (1987).","journal-title":"J. Immunol."},{"key":"BF01983470_CR17","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1083\/jcb.111.3.909","volume":"111","author":"M. Aridor","year":"1990","unstructured":"M. Aridor, L. M. Traub and R. Sagi-Eisenberg,Exocytosis in mast cells by basic secretagogues: evidence for direct activation of GTP-binding proteins. J. Cell Biol.111, 909\u2013917 (1990).","journal-title":"J. Cell Biol."},{"key":"BF01983470_CR18","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/0008-8749(92)90167-N","volume":"141","author":"M. A. Mulkins","year":"1992","unstructured":"M. A. Mulkins, N. G. May and R. A. Lewis,Mycophenolic acid inhibits the degranulation of rat peritoneal mast cells. Cellular Immunol.141, 508\u2013517 (1992).","journal-title":"Cellular Immunol."},{"key":"BF01983470_CR19","first-page":"17","volume":"41","author":"T. Ishizaka","year":"1982","unstructured":"T. Ishizaka,Biochemical analysis of triggering signals induced by bridging of IgE receptors. Fed. Proc.41, 17\u201321 (1982).","journal-title":"Fed. Proc."},{"key":"BF01983470_CR20","doi-asserted-by":"crossref","first-page":"161","DOI":"10.4049\/jimmunol.139.1.161","volume":"139","author":"J. A. Warner","year":"1987","unstructured":"J. A. Warner, K. B. Yancey and D. W. J. MacGlashan,The effect of pertussis toxin on mediator release from human basophils. J. Immunol.139, 161\u2013165 (1987).","journal-title":"J. Immunol."},{"key":"BF01983470_CR21","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/0014-5793(90)80023-C","volume":"259","author":"M. Mousli","year":"1990","unstructured":"M. Mousli, C. Bronner, Y. Landry, J. Bockaert and B. Rouot,Direct activation of GTP-binding regulatory proteins (G-proteins) by substance P and compound 48\/80. FEBS Lett.259, 260\u2013262 (1990).","journal-title":"FEBS Lett."},{"key":"BF01983470_CR22","first-page":"816","volume":"38","author":"J. L. Bueb","year":"1990","unstructured":"J. L. Bueb, M. Mousli, C. Bronner, B. Rouot and Y. Landry,Activation of Gi-like proteins, a receptor-independent effect of kinins in mast cells. Mol. Pharmacol.38, 816\u2013822 (1990).","journal-title":"Mol. Pharmacol."},{"key":"BF01983470_CR23","doi-asserted-by":"crossref","first-page":"2973","DOI":"10.1016\/0024-3205(83)90648-3","volume":"32","author":"K. Saeki","year":"1983","unstructured":"K. Saeki, S. Ikeda and M. Nishibori,Calcium requirement for the inhibition by theophylline of histamine release from mast cells. Life Sci.32, 2973\u20132980 (1983).","journal-title":"Life Sci."},{"key":"BF01983470_CR24","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/0166-2236(89)90091-X","volume":"12","author":"K. P. Huang","year":"1989","unstructured":"K. P. Huang,The mechanism of protein kinase C activation. Trends Neurosci.12, 425\u2013432 (1989).","journal-title":"Trends Neurosci."},{"key":"BF01983470_CR25","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/0165-6147(91)90545-4","volume":"12","author":"G. Powis","year":"1991","unstructured":"G. Powis,Signalling Targets for Anticancer Drug Development. Trends Pharmacol. Sci.12, 188\u2013194 (1991).","journal-title":"Trends Pharmacol. Sci."},{"key":"BF01983470_CR26","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1007\/BF00689696","volume":"28","author":"R. Hoffman","year":"1991","unstructured":"R. Hoffman and E. S. Newlands,Role of protein kinase C in adriamycin-induced erythroid differentiation of K562 cells. Cancer Chemother. Pharmacol.28, 102\u2013104 (1991).","journal-title":"Cancer Chemother. Pharmacol."},{"key":"BF01983470_CR27","doi-asserted-by":"crossref","first-page":"548","DOI":"10.4049\/jimmunol.134.1.548","volume":"134","author":"A. S. Heiman","year":"1985","unstructured":"A. S. Heiman and F. T. Crews,Characterization of the effects of phorbol esters on rat mast cell secretion. J. Immunol.134, 548\u2013555 (1985).","journal-title":"J. Immunol."},{"key":"BF01983470_CR28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF01987883","volume":"37","author":"L. M. Botana","year":"1992","unstructured":"L. M. Botana, A. Alfonso, M. A. Botana, M. R. Vieytes, M. C. Louzao and A. G. Cabado,Influence of protein kinase C, cAMP and phosphatase activity on histamine release produced by compound 48\/80 and sodium fluoride on rat mast cells. Agents and Actions37, 1\u20137 (1992).","journal-title":"Agents and Actions"},{"key":"BF01983470_CR29","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0006-2952(92)90667-8","volume":"43","author":"W. N. Hait","year":"1992","unstructured":"W. N. Hait and D. T. Aftab,Rational design and preclinical pharmacology of drugs for reversing multidrug resistance. Biochem. Pharmacol.43, 103\u2013107 (1992).","journal-title":"Biochem. Pharmacol."},{"key":"BF01983470_CR30","doi-asserted-by":"crossref","unstructured":"K. Dano,Active outward transport ofdaunomycin. Biochem. Biophys. Acta323 (1973).","DOI":"10.1016\/0005-2736(73)90191-0"},{"key":"BF01983470_CR31","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/0968-0004(90)90192-E","volume":"15","author":"P. Cohen","year":"1990","unstructured":"P. Cohen, C. F. Holmes and Y. Tsukitani,Okadaic acid: A new probe for the study of cellular regulation. Trends Biochem. Sci.15, 98\u2013102 (1990).","journal-title":"Trends Biochem. Sci."},{"key":"BF01983470_CR32","unstructured":"M. D. Est\u00e9vez, M. R. Vieytes, A. Alfonso, R. Riguera and L. M. Botana,Study of the activation mechanism of human GRF (1\u201329) NH 2 on rat mast cell histamine release. (Submitted)"}],"container-title":["Agents and Actions"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01983470.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01983470\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01983470","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T00:27:59Z","timestamp":1683160079000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01983470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,10]]},"references-count":32,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[1994,10]]}},"alternative-id":["BF01983470"],"URL":"https:\/\/doi.org\/10.1007\/bf01983470","relation":{},"ISSN":["0065-4299","1420-908X"],"issn-type":[{"value":"0065-4299","type":"print"},{"value":"1420-908X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,10]]}}}