{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T22:44:27Z","timestamp":1785710667876,"version":"3.56.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1995,2,1]],"date-time":"1995-02-01T00:00:00Z","timestamp":791596800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digest Dis Sci"],"published-print":{"date-parts":[[1995,2]]},"DOI":"10.1007\/bf02065431","type":"journal-article","created":{"date-parts":[[2005,8,13]],"date-time":"2005-08-13T13:11:08Z","timestamp":1123938668000},"page":"419-426","source":"Crossref","is-referenced-by-count":7,"title":["Toxic effects of cholelitholytic solvents on gallbladder and liver"],"prefix":"10.1007","volume":"40","author":[{"given":"Chiung-Yu","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuo-Kuan","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan-Hwa","family":"Chow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tay-Chen","family":"Leow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tse-Chuan","family":"Chou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi-Zhang","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF02065431_CR1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1056\/NEJM198501243120406","volume":"312","author":"MJ Allen","year":"1985","unstructured":"Allen MJ, Borody TJ, Bugliosi TF, May GR, LaRusso NF, Thistle JL: Rapid dissolution of gallstones by methyltert-butyl ether: Preliminary observations. N Engl J Med 312:217\u2013220, 1985","journal-title":"N Engl J Med"},{"key":"BF02065431_CR2","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1056\/NEJM198903093201004","volume":"320","author":"JL Thistle","year":"1989","unstructured":"Thistle JL, May GR, Bender CE, Williams HJ, LeRoy AJ, Nelson PE, Peine CJ, Petersen BT, McCullough JE: Dissolution of cholesterol gallbladder stones by methyltert-butyl ether administered by percutaneous transphepatic catheter. N Engl J Med 320:633\u2013639, 1989","journal-title":"N Engl J Med"},{"key":"BF02065431_CR3","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/bjs.1800770111","volume":"77","author":"JP Neoptolemos","year":"1990","unstructured":"Neoptolemos JP, Hall C, O'Connor HJ, Murray WR, Carr-Locke DL: Methyltert-butyl ether for treating bile duct stones: The British experience. Br J Surg 77:32\u201335, 1990","journal-title":"Br J Surg"},{"key":"BF02065431_CR4","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0889-8553(21)00540-9","volume":"20","author":"AF Hofmann","year":"1991","unstructured":"Hofmann AF, Schteingart CD, vanSonnenberg E, Esch O, Zakko SF: Contact dissolution of cholesterol gallstones with organic solvents. Gastroenterol Clin North Am 20:183\u2013199, 1991","journal-title":"Gastroenterol Clin North Am"},{"key":"BF02065431_CR5","unstructured":"Zakko SF, Scirica JC, Guttermuth CF, Dodge J, Rashid S, Khan M, Srb SM, Ramsby GR, Hajjar JJ: Ethyl propionate for cholesterol gallstone dissolution: More effective and less cytotoxic than MTBE. Gastroenterology 102:A339, 1992 (abstract)"},{"key":"BF02065431_CR6","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1620\/tjem.125.121","volume":"125","author":"Y Nakamura","year":"1978","unstructured":"Nakamura Y, Suzuki N, Takahashi W, Sato T: Study on dissolution and disintegration of calcium bilirubinate stone. Tohoku J Exp Med 125:121\u2013134, 1978","journal-title":"Tohoku J Exp Med"},{"key":"BF02065431_CR7","doi-asserted-by":"crossref","first-page":"497","DOI":"10.3109\/00365528109182004","volume":"16","author":"U Leuschner","year":"1981","unstructured":"Leuschner U, Wurbs D, Baumgartel H, Helms EB, Classen M: Alternating treatment of common bile duct stones with a modified glyceryl-1-monooctanoate preparation and a bile acid-EDTA solution by nasobiliary tube. Scand J Gastroenterol 16:497\u2013503, 1981","journal-title":"Scand J Gastroenterol"},{"key":"BF02065431_CR8","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0168-8278(92)90124-8","volume":"14","author":"U Wosiewitz","year":"1992","unstructured":"Wosiewitz U, Sabinski F, Haus C, Guldutuna S, Leuschner U: Experimental dissolution of pigment gallstone material using alkaline EDTA and adjuvant bile salts\/non-bile salt detergents, thiol and urea, with respect to local chemolysis. J Hepatol 14:7\u201315, 1992","journal-title":"J Hepatol"},{"key":"BF02065431_CR9","first-page":"1674","volume":"88","author":"U Leuschner","year":"1985","unstructured":"Leuschner U, Baumgartel H, Wosiewitz U: Dissolution of black pigment stones of the gallbladder. Gastroenterology 88:1674, 1985 (abstract)","journal-title":"Gastroenterology"},{"key":"BF02065431_CR10","first-page":"1666","volume":"88","author":"H Igimi","year":"1985","unstructured":"Igimi H, Asakawa S, Kataoka A, Shimura H: Clinical trials of DMSO on the cases with intrahepatic stones. Gastroenterology 88:1666, 1985 (abstract)","journal-title":"Gastroenterology"},{"key":"BF02065431_CR11","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0168-8278(89)90138-4","volume":"9","author":"KY Dai","year":"1989","unstructured":"Dai KY, Montet JC, Zhao XM, Amic J, Montet AM: Dissolution of human brown pigment biliary stones. J Hepatol 9:301\u2013311, 1989","journal-title":"J Hepatol"},{"key":"BF02065431_CR12","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1007\/BF01296436","volume":"37","author":"CH Su","year":"1992","unstructured":"Su CH, Lui WY, P'Eng FK: Relative prevalence of gallstone diseases in Taiwan: A nationwide cooperative study. Dig Dis Sci 37:764\u2013768, 1992","journal-title":"Dig Dis Sci"},{"key":"BF02065431_CR13","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1016\/0016-5085(90)90355-5","volume":"98","author":"PE Nelson","year":"1990","unstructured":"Nelson PE, Moyer TP, Thistle JL: Dissolution of calcium bilirubinate and calcium carbonate debris remaining after methyl-tert-butyl ether dissolution of cholesterol gallstones. Gastroenterology 98:1345\u20131350, 1990","journal-title":"Gastroenterology"},{"key":"BF02065431_CR14","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1002\/hep.1840160422","volume":"16","author":"O Esch","year":"1992","unstructured":"Esch O, Spinosa JC, Hamilton RL, Crombie DL, Schteingart CD, Rondinone JF, D'Agostino HB, Lillienau J, Hofmann AF: Acute effects of topical methyltert-butyl ether or ethyl propionate on gallbladder histology in animals: A comparison of two solvents for contact dissolution of cholesterol gallstones. Hepatology 16:984\u2013991, 1992","journal-title":"Hepatology"},{"key":"BF02065431_CR15","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1016\/0016-5085(91)90674-A","volume":"100","author":"E vanSonnenberg","year":"1991","unstructured":"vanSonnenberg E, Zakko S, Hofmann AF, D'Agostino HB, Jinich H, Hoyt DB, Miyai K, Ramsby G, Moossa AR: Human gallbladder morphology after gallstone dissolution with methyltert-butyl ether. Gastroenterology 100:1718\u20131723, 1991","journal-title":"Gastroenterology"},{"key":"BF02065431_CR16","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/BF01300756","volume":"36","author":"U Leuschner","year":"1991","unstructured":"Leuschner U, Hellstern A, Schmidt K, Hubner K, Fischer H, Guldutuna S, Jubner K, Leuschner M: Gallstone dissolution with methyltert-butyl ether in 120 patients: Efficacy and safety. Dig Dis Sci 36:193\u2013199, 1991","journal-title":"Dig Dis Sci"},{"key":"BF02065431_CR17","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1097\/00004424-199001000-00015","volume":"25","author":"G Adam","year":"1990","unstructured":"Adam G, Knuechel R, Vorwerk D, Held C, Guenther RW: Tissue response of the biliary and digestive system of rabbits after MTBE infusion into the gallbladder. Invest Radiol 25:58\u201361, 1990","journal-title":"Invest Radiol"},{"key":"BF02065431_CR18","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/0022-4804(92)90257-Z","volume":"53","author":"R Akimoto","year":"1992","unstructured":"Akimoto R, Rieger E, Moossa AR, Hofmann AF, Wahlstrom HE: Systemic and local toxicity in the rat of methyltert-butyl ether: A gallstone dissolution agent. J Surg Res 53:572\u2013577, 1992","journal-title":"J Surg Res"},{"key":"BF02065431_CR19","doi-asserted-by":"crossref","unstructured":"Amelsberg A, vanSonnenberg E, Esch O, Schteingart CD, Hofmann AF: Contact dissolution of cholesterol gallstones with ethyl propionate (EP): Further clinical experience. Hepatology 18:98A, 1993 (abstract)","DOI":"10.1016\/0270-9139(93)91921-E"},{"key":"BF02065431_CR20","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1002\/hep.1840180222","volume":"18","author":"O Esch","year":"1993","unstructured":"Esch O, Schteingart CD, Pappert D, Kirby D, Streich R, Hofmann AF: Increased blood levels of methyl tert-butyl ether but not of ethyl propionate during instillation with contact gallstone dissolution agents in the pig. Hepatology 18:373\u2013379, 1993","journal-title":"Hepatology"},{"key":"BF02065431_CR21","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1159\/000198553","volume":"21","author":"J Lohse","year":"1981","unstructured":"Lohse J, Verine HJ, Sarles H: Study on pancreatic stones. Digestion 21:125\u2013132, 1981","journal-title":"Digestion"},{"key":"BF02065431_CR22","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1056\/NEJM197902153000704","volume":"300","author":"SP Dretler","year":"1979","unstructured":"Dretler SP, Pfister RC, Newhouse JH: Renal-stone dissolution via percutaneous nephrostomy. N Engl J Med 300:341\u2013343, 1979","journal-title":"N Engl J Med"},{"key":"BF02065431_CR23","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1440-1746.1992.tb00991.x","volume":"7","author":"XZ Lin","year":"1992","unstructured":"Lin XZ, Lin CY, Chang TT, Shin JS, Liou TC, Chang KK: Choloedocholithiasis treated by ethylenediamine tetraacetic acid infusion through endoscopic nasobiliary catheter. J Gastroenterol Hepatol 7:335\u2013338, 1992","journal-title":"J Gastroenterol Hepatol"},{"key":"BF02065431_CR24","first-page":"1907","volume-title":"Physicians' Desk Reference","author":"MA Duffy","year":"1993","unstructured":"Duffy MA, Williams C, Hiller KV, Schumacher MM, Karst EA, Akerlind JK, Napolitano LV: Physicians' Desk Reference, 47 ed. Montvale, New Jersey, Medical Economics Data, 1993, p 1907","edition":"47 ed."},{"key":"BF02065431_CR25","first-page":"1417","volume-title":"Harrison's Principles of Internal Medicine","author":"AS Cohen","year":"1991","unstructured":"Cohen AS: Amyloidosis.In Harrison's Principles of Internal Medicine, 12th ed. JD Wilson, E Braunwald, KJ Isselbacher, RG Petersdorf, JB Martin, AS Fauci, RK Root (eds). New York, McGraw-Hill, 1991, pp 1417\u20131421","edition":"12th ed."},{"key":"BF02065431_CR26","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1001\/jama.1980.03310180047034","volume":"244","author":"RS Muther","year":"1980","unstructured":"Muther RS, Bennett WM: Effects of dimethyl sulfoxide on renal function in man. JAMA 244:2081\u20132083, 1980","journal-title":"JAMA"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02065431.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02065431\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02065431","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,15]],"date-time":"2021-07-15T15:36:32Z","timestamp":1626363392000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02065431"}},"subtitle":["A piglet model study"],"short-title":[],"issued":{"date-parts":[[1995,2]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1995,2]]}},"alternative-id":["BF02065431"],"URL":"https:\/\/doi.org\/10.1007\/bf02065431","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,2]]}}}