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Further clinical and biochemical investigations established primary hyperparathyroidism (PHP) in at least 40 (32%) patients, an incidence of PHP of 89.6\u00b141.5 per 100,000 patients per year. The incidence of PHP in males and females was 31.5 and 124.2 per 100,000, respectively. The highest incidence was found in females &gt;66 years of age (268.8 per 100,000). Nineteen (48%) patients showed classical symptoms of PHP, 14 (35%) patients were minimally symptomatic, and 7 (17%) patients were asymptomatic. The incidence and symptomatology of PHP in Austria is nearly the same as in other countries. Because of the multiple actions of parathyroid hormone in the body, PHP can cause debilitating symptoms but too often it remains undiagnosed clinically. Routine calcium determinations are very important and PHP must always be considered in the differential diagnosis, especially in minimally symptomatic patients.<\/jats:p>","DOI":"10.1007\/bf02067385","type":"journal-article","created":{"date-parts":[[2005,8,13]],"date-time":"2005-08-13T21:45:46Z","timestamp":1123969546000},"page":"777-782","source":"Crossref","is-referenced-by-count":13,"title":["Primary hyperparathyroidism in Austria: Results of an 8\u2010year prospective study"],"prefix":"10.1002","volume":"16","author":[{"given":"Bruno","family":"Niederle","sequence":"first","affiliation":[{"name":"Department of Surgery I Ludwig Bolizmann Institute for Clinical Endocrinology Department of Internal Medicine II University of Vienna Medical School Austria"},{"name":"Department of Internal Medicine Krankenhaus Waidhofen\/Thaya Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ludwig","family":"Stamm","sequence":"additional","affiliation":[{"name":"Department of Surgery I Ludwig Bolizmann Institute for Clinical Endocrinology Department of Internal Medicine II University of Vienna Medical School Austria"},{"name":"Department of Internal Medicine Krankenhaus Waidhofen\/Thaya Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Friedrich","family":"L\u00e4ngle","sequence":"additional","affiliation":[{"name":"Department of Surgery I Ludwig Bolizmann Institute for Clinical Endocrinology Department of Internal Medicine II University of Vienna Medical School Austria"},{"name":"Department of Internal Medicine Krankenhaus Waidhofen\/Thaya Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edith","family":"Schubert","sequence":"additional","affiliation":[{"name":"Department of Surgery I Ludwig Bolizmann Institute for Clinical Endocrinology Department of Internal Medicine II University of Vienna Medical School Austria"},{"name":"Department of Internal Medicine Krankenhaus Waidhofen\/Thaya Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Woloszczuk","sequence":"additional","affiliation":[{"name":"Department of Surgery I Ludwig Bolizmann Institute for Clinical Endocrinology Department of Internal Medicine II University of Vienna Medical School Austria"},{"name":"Department of Internal Medicine Krankenhaus Waidhofen\/Thaya Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rudolf","family":"Prager","sequence":"additional","affiliation":[{"name":"Department of Surgery I Ludwig Bolizmann Institute for Clinical Endocrinology Department of Internal Medicine II University of Vienna Medical School Austria"},{"name":"Department of Internal Medicine Krankenhaus Waidhofen\/Thaya Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1992,7]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"1343","article-title":"Therapeutische Versuche bei Ostitis fibrosa generalisata Exstirpation eines Epithelk\u00f6rperchentumors","volume":"38","author":"Mandl F.","year":"1925","journal-title":"Wien. klin. 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