{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T13:45:18Z","timestamp":1780580718118,"version":"3.54.1"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[1996,6,1]],"date-time":"1996-06-01T00:00:00Z","timestamp":833587200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digest Dis Sci"],"published-print":{"date-parts":[[1996,6]]},"DOI":"10.1007\/bf02088230","type":"journal-article","created":{"date-parts":[[2005,8,14]],"date-time":"2005-08-14T04:43:55Z","timestamp":1123994635000},"page":"1145-1149","source":"Crossref","is-referenced-by-count":58,"title":["Safety of first trimester exposure to histamine H2 blockers"],"prefix":"10.1007","volume":"41","author":[{"given":"Laura A.","family":"Magee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilda","family":"Inocencion","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laveena","family":"Kamboj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frances","family":"Rosetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gideon","family":"Koren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"issue":"10","key":"BF02088230_CR1","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1056\/NEJM199409083311007","volume":"331","author":"CE Pope","year":"1994","unstructured":"Pope CE: Acid-reflux disorders. N Engl J Med 331(10):656\u2013660, 1994","journal-title":"N Engl J Med"},{"key":"BF02088230_CR2","unstructured":"Advertising supplement. Warner Wellcome Consumer Healthcare, Glaxo, January 1995"},{"key":"BF02088230_CR3","volume-title":"Goodman and Gilman's The Pharmacological Basis of Therapeutics","year":"1990","unstructured":"Goodman Gilman A, Rall TW, Nies AS, Taylor P (eds): Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed. New York, McGraw-Hill, 1990","edition":"8th ed."},{"key":"BF02088230_CR4","volume-title":"Drugs in Pregnancy and Lactation","author":"GG Briggs","year":"1994","unstructured":"Briggs GG, Freeman RK, Yaffe SJ: Drugs in Pregnancy and Lactation, 4th ed. Baltimore, Williams and Wilkins, 1994","edition":"4th ed."},{"issue":"215","key":"BF02088230_CR5","first-page":"253","volume":"54","author":"DG Colin Jones","year":"1985","unstructured":"Colin Jones DG, Langman MJS, Lawson DH, Vessey MP: Post-marketing surveillance of the safety of cimetidine: Twelve-month morbidity report. Q J Med 54(215):253\u2013268, 1985","journal-title":"Q J Med"},{"key":"BF02088230_CR6","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S0140-6736(89)90058-5","volume":"1","author":"PD Knott","year":"1989","unstructured":"Knott PD, Thorpe SS, Lamont CAR: Congenital renal dysgenesis possibly due to captopril. Lancet 1:451, 1989","journal-title":"Lancet"},{"issue":"2","key":"BF02088230_CR7","first-page":"91","volume":"19","author":"GR Corazza","year":"1982","unstructured":"Corazza GR, Gasbarrini G, DiNisio Q, Zulli P: Cimetidine (Tagamet) in peptic ulcer therapy during pregnancy: a report of three cases. Clin Trials J 19(2):91\u201392, 1982","journal-title":"Clin Trials J"},{"key":"BF02088230_CR8","first-page":"87","volume":"134","author":"G Glade","year":"1980","unstructured":"Glade G, Saccar CL, Pereira GR: Cimetidine in pregnancy: Apparent transient liver impairment in the newborn. Am J Dis Child 134:87\u201388, 1980","journal-title":"Am J Dis Child"},{"issue":"4","key":"BF02088230_CR9","first-page":"130","volume":"16","author":"G Armentano","year":"1989","unstructured":"Armentano G, Bracco PL, DiSilverio C: Ranitidine in the treatment of reflux oesophagitis in pregnancy. Clin Exp Obstet Gynecol 16(4):130\u2013133, 1989","journal-title":"Clin Exp Obstet Gynecol"},{"key":"BF02088230_CR10","first-page":"1","volume":"22","author":"S Cipriani","year":"1983","unstructured":"Cipriani S, Conti R, Vella G: Ranitidina in pregnancy. Three case reports. Clin Eur 22:1, 1983 (in Spanish)","journal-title":"Clin Eur"},{"issue":"1","key":"BF02088230_CR11","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1055\/s-2007-999336","volume":"8","author":"G Koren","year":"1991","unstructured":"Koren G, Zemlickis DM: Outcome of pregnancy after first trimester exposure to H2 receptor antagonists. Am J Perinatol 8(1):37\u201338, 1991","journal-title":"Am J Perinatol"},{"key":"BF02088230_CR12","volume-title":"A Clinician's Guide","author":"Toxicology Maternal-Fetal","year":"1994","unstructured":"Maternal-Fetal Toxicology; A Clinician's Guide. New York, Marcel Dekker, 1994"},{"key":"BF02088230_CR13","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0022-3476(64)80188-8","volume":"64","author":"PM Marden","year":"1964","unstructured":"Marden PM, Smith DW, McDonald MJ: Congenital anomalies in the newborn infant, including minor variations. J Pediatr 64:357\u2013371, 1964","journal-title":"J Pediatr"},{"issue":"6","key":"BF02088230_CR14","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/S0022-3476(69)80224-6","volume":"74","author":"R Usher","year":"1969","unstructured":"Usher R, McLean F: Intrauterine growth of live-born caucasian infants at sea level: standards obtained from measurements in 7 dimensions of infants born between 25 and 44 weeks of gestation. J Pediatr 74(6):901\u2013910, 1969","journal-title":"J Pediatr"},{"key":"BF02088230_CR15","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/978-1-4899-0536-9_8","volume-title":"Early Identification of Children at Risk","author":"WK Frankenburg","year":"1985","unstructured":"Frankenburg WK: The Denver approach to early case finding.In Early Identification of Children at Risk. WK Frankenburg, RN Emde, JW Sullivan (eds). New York, Plenum Press, 1985, pp 135\u2013158"},{"key":"BF02088230_CR16","volume-title":"Statistical Methods for Rates and Proportions","author":"JL Fleiss","year":"1973","unstructured":"Fleiss JL: Statistical Methods for Rates and Proportions. New York, John Wiley & Sons, 1973"},{"key":"BF02088230_CR17","doi-asserted-by":"crossref","first-page":"366","DOI":"10.7326\/0003-4819-118-5-199303010-00008","volume":"118","author":"TH Baron","year":"1993","unstructured":"Baron TH, Ramirez B, Richter JE: Gastrointestinal motility disorders during pregnancy. Ann Intern Med 118:366\u2013375, 1993","journal-title":"Ann Intern Med"},{"key":"BF02088230_CR18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0002-9378(67)90122-6","volume":"98","author":"L de P Castro","year":"1967","unstructured":"Castro L de P: Reflux esophagitis as the cause of heartburn in pregnancy. Am J Obstet Gynecol 98:1\u201310, 1967","journal-title":"Am J Obstet Gynecol"},{"key":"BF02088230_CR19","volume-title":"Chemically Induced Birth Defects","author":"JL Schardein","year":"1985","unstructured":"Schardein JL: Chemically Induced Birth Defects. New York, Marcel Dekker, 1985"},{"key":"BF02088230_CR20","volume-title":"Congenital Abnormalities in Infancy","year":"1971","unstructured":"Normal AP (ed): Congenital Abnormalities in Infancy, 2nd ed. Oxford, Blackwell Scientific Publications, 1971","edition":"2nd ed."}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02088230.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02088230\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02088230","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,14]],"date-time":"2019-05-14T10:05:02Z","timestamp":1557828302000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02088230"}},"subtitle":["A prospective cohort study"],"short-title":[],"issued":{"date-parts":[[1996,6]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1996,6]]}},"alternative-id":["BF02088230"],"URL":"https:\/\/doi.org\/10.1007\/bf02088230","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,6]]}}}